tiletamine hydrochloride has been researched along with Alkaptonuria in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.65) | 18.2507 |
| 2000's | 4 (9.30) | 29.6817 |
| 2010's | 24 (55.81) | 24.3611 |
| 2020's | 13 (30.23) | 2.80 |
| Authors | Studies |
|---|---|
| Arslan Gulten, Z; Arslan, N; Aydogan, A; Bahceci, H; Eroglu Erkmen, S; Karalar Pekuz, OK; Ozturk, T; Teke Kisa, P; Uysal, S; Yuce Inel, T | 1 |
| Arnoux, JB; Bou-Gharios, G; Davison, AS; Gallagher, JA; Hughes, AT; Imrich, R; M, K; Milan, AM; Norman, BP; Olsson, B; Ranganath, LR; Rudebeck, M | 1 |
| Gonzalez-Lamuño, D; Puente, N; Riancho, JA | 1 |
| Ranganath, LR; Sireau, N | 1 |
| Bou-Gharios, G; Gallagher, JA; Hughes, AT; Hughes, JH; Jarvis, JC; Judd, S; Milan, AM; Ranganath, LR; Sutherland, H; Wilson, PJM | 1 |
| Davison, AS; Gallagher, JA; Hughes, AT; Milan, AM; Ranganath, LR; Sireau, N | 1 |
| Cooper, MS; Davison, AS; Deutz, NEP; Fitzgerald, R; Gallagher, JA; Ghane, P; Hughes, AT; Jarvis, JC; Khedr, M; Markinson, L; Milan, AM; Norman, BP; Psarelli, EE; Ranganath, LR; Sutherland, H | 1 |
| Häberle, J | 1 |
| Arnoux, JB; Braconi, D; Briggs, M; Bröijersén, A; Bygott, H; Cox, TF; Davison, AS; Dillon, JP; Fisher, M; FitzGerald, R; Gallagher, JA; Genovese, F; Glasova, H; Hall, AK; Hughes, AT; Hughes, JH; Imrich, R; Jarvis, JC; Khedr, M; Laan, D; Le Quan Sang, KH; Loftus, N; Luangrath, E; Lukáčová, O; Milan, AM; Mistry, A; Mlynáriková, V; Norman, BP; Olsson, B; Psarelli, EE; Ranganath, LR; Rhodes, NP; Rovenský, J; Rudebeck, M; Santucci, A; Scott, C; Sedláková, J; Shweihdi, E; Sireau, N; Stančík, R; Szamosi, J; Taylor, S; van Kan, C; Vinjamuri, S; Vrtíková, E; Webb, C; West, E; Záňová, E; Zatkova, A | 1 |
| Davidson, J; Gallagher, JA; Ranganath, LR; Vinjamuri, S | 1 |
| Gallagher, JA; Khedr, M; Ranganath, LR; Vinjamuri, S | 1 |
| Fisher, MF; Heseltine, T; Khedr, M; Ranganath, LR | 1 |
| Heiner-Fokkema, MR; van Spronsen, FJ; Wolffenbuttel, BHR | 1 |
| Davison, AS; Devine, J; Gallagher, JA; Harrold, JA; Hughes, AT; Hughes, G; J C G, H; Khedr, M; Milan, AM; Norman, BP; Ranganath, LR; Usher, J | 1 |
| Barton, GJ; Briggs, M; Cox, TF; Daroszewska, A; Davison, AS; Devine, JM; Dillon, JP; Fisher, M; Gallagher, JA; Griffin, R; Harrold, J; Hughes, AT; Hughes, G; Jarvis, JC; Jones, A; Judd, S; Khedr, M; Loftus, N; McCormick, M; Milan, AM; Psarelli, EE; Ranganath, LR; Sireau, N; Taylor, S; Usher, JL; Vinjamuri, S; West, E | 1 |
| Adam, D | 1 |
| Davison, AS; Gallagher, JA; Hughes, AT; Jarvis, JC; Milan, AM; Norman, BP; Ranganath, LR; Roberts, NB; Ross, GA; Sutherland, H | 1 |
| Curtis, SL; Gallagher, JA; Milan, AM; Norman, BP; Olsson, B; Ranganath, LR; Roberts, NB | 1 |
| Alqahtani, A; Blum, A; Feillet, F; Guéant, JL; Henn-Ménétré, S; Jeannesson, E; Merten, M; Renard, E; Sloboda, N; Wiedemann, A | 1 |
| Cox, TF; Davison, AS; Gallagher, JA; Hughes, AT; Khedr, M; Milan, AM; Psarelli, EE; Ranganath, LR; Rhodes, NP; Rovensky, J | 1 |
| Gallagher, JA; Jarvis, JC; Keenan, CM; Preston, AJ; Ranganath, LR; Sutherland, H; Taylor, AM; Williams, DP; Wilson, PJ; Wlodarski, B | 1 |
| Lock, E; Ranganath, LR; Timmis, O | 1 |
| Ayoob, H; Braconi, D; Briggs, MC; Bygott, H; Christensen, P; Cox, TF; Cronlund, A; Dutton, JJ; Fitzgerald, R; Gallagher, JA; Genovese, F; Hall, AK; Hughes, AT; Imrich, R; Jarvis, JC; Junestrand, C; Kullenberg, T; Laan, D; Le Quan Sang, KH; McCaffrey, J; Milan, AM; Nemethova, M; Olsson, B; Psarelli, EE; Ranganath, LR; Ross, G; Rovensky, J; Rudebeck, M; Santucci, A; Sireau, N; Svensson, L; Szamosi, J; Timmis, OG; van Kan, C; Zatkova, A | 1 |
| Christensen, P; Davison, AS; Dutton, JJ; Gallagher, JA; Hughes, AT; Milan, AM; Ranganath, LR; Ross, G | 1 |
| Barshop, BA; Gangoiti, JA; Gertsman, I; Nyhan, WL | 1 |
| Arnoux, JB; Brassier, A; de Lonlay, P; Dubois, S; Grisel, C; Job-Deslandre, C; Le Quan Sang, KH; Ranganath, L; Servais, A; Sireau, N; Wippf, J | 1 |
| Bukhari, M; Jackson, DJ; Mistry, JB; Taylor, AM | 1 |
| Gallagher, JA; Ranganath, LR; Timmis, OG | 1 |
| Davison, AS; Gallagher, JA; Milan, AM; Ranganath, LR | 1 |
| Bernardini, G; Botta, M; Braconi, D; Dreassi, E; Geminiani, M; Laschi, M; Manetti, F; Marzocchi, B; Millucci, L; Santucci, A | 1 |
| Knispel, JD; Leventhal, JS; McNiff, JM; Yin, ES | 1 |
| Curtis, S; Davison, AS; Devine, J; Gallagher, JA; Hughes, AT; Khedr, M; Milan, AM; Ranganath, LR; Usher, J | 1 |
| Anolik, R; Pomeranz, MK; Yancovitz, M | 1 |
| Bernardini, I; Bryant, J; Gahl, WA; Introne, WJ; Kayser, MA; Moylan, E; O'Brien, KE; Perry, MB; Reynolds, JC; Sachdev, V; Suwannarat, P; Troendle, J; Tsilou, E | 1 |
| Cox, TF; Ranganath, L | 1 |
| Cox, TF; Ranganath, LR | 1 |
| Cox, TM | 1 |
| Anderson, PD; Anikster, Y; Bernardini, I; Fitzpatrick, DL; Gahl, WA; Gerber, LH; Huizing, M; Introne, WJ; Murphey, MD; Perry, MB; Phornphutkul, C | 1 |
| Lorenzini, S; Mannoni, A; Selvi, E | 1 |
| Jaffe, IA; Keller, JM; Macaulay, W; Nercessian, OA | 1 |
| Bernardini, I; Gahl, WA; Gerber, LH; Kaiser-Kupfer, MI; O'Brien, K; Perry, MB; Rubin, BI; Sebring, N; Suwannarat, P; Tsilou, E | 1 |
| Anikster, Y; Gahl, WA; Nyhan, WL | 1 |
| Maeda, Y; Oda, K; Suzuki, T; Suzuki, Y; Yoshikawa, Y | 1 |
8 review(s) available for tiletamine hydrochloride and Alkaptonuria
| Article | Year |
|---|---|
Efficacy of Phenylalanine- and Tyrosine-Restricted Diet in Alkaptonuria Patients on Nitisinone Treatment: Case Series and Review of Literature.
Topics: Adult; Alkaptonuria; Cyclohexanones; Diet; Dietary Proteins; Female; Humans; Male; Middle Aged; Nitrobenzoates; Phenylalanine; Tyrosine | 2022 |
Clinical development innovation in rare diseases: overcoming barriers to successful delivery of a randomised clinical trial in alkaptonuria-a mini-review.
Topics: Alkaptonuria; Cyclohexanones; Homogentisic Acid; Humans; Multicenter Studies as Topic; Nitrobenzoates; Randomized Controlled Trials as Topic; Rare Diseases | 2023 |
Alkaptonuria - Many questions answered, further challenges beckon.
Topics: Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Homogentisic Acid; Humans; Mice; Nitrobenzoates; Tyrosine | 2020 |
Suitability of nitisinone for alkaptonuria.
Topics: Alkaptonuria; Cyclohexanones; Enzyme Inhibitors; Humans; Nitrobenzoates | 2020 |
The role of nitisinone in tyrosine pathway disorders.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Biomedical Research; Cyclohexanones; Enzyme Inhibitors; Humans; Nitrobenzoates; Off-Label Use; Tyrosinemias | 2014 |
Old treatments for new insights and strategies: proposed management in adults and children with alkaptonuria.
Topics: Adult; Age Factors; Alkaptonuria; Antioxidants; Child; Cyclohexanones; Humans; Nitrobenzoates; Ochronosis; Phenylalanine; Tyrosine | 2015 |
Acute fatal metabolic complications in alkaptonuria.
Topics: Acute Disease; Alkaptonuria; Cyclohexanones; Erythrocytes; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Metabolic Diseases; Nitrobenzoates; Oxidation-Reduction | 2016 |
New developments in ochronosis: review of the literature.
Topics: Alkaptonuria; Arthroplasty, Replacement; Cyclohexanones; Enzyme Inhibitors; Humans; Joint Diseases; Nitrobenzoates; Ochronosis | 2005 |
4 trial(s) available for tiletamine hydrochloride and Alkaptonuria
| Article | Year |
|---|---|
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial.
Topics: Adult; Aged; Alkaptonuria; Cyclohexanones; Drug Administration Schedule; Enzyme Inhibitors; Female; Homogentisic Acid; Humans; Internationality; Longitudinal Studies; Male; Middle Aged; Nitrobenzoates; Single-Blind Method; Treatment Outcome | 2020 |
Quantification of the flux of tyrosine pathway metabolites during nitisinone treatment of Alkaptonuria.
Topics: Adult; Alkaptonuria; Cyclohexanones; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Phenylalanine; Pigments, Biological; Tandem Mass Spectrometry; Tyrosine | 2019 |
Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid
Topics: Adult; Alkaptonuria; Cyclohexanones; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Research Design; Tyrosine | 2016 |
A 3-year randomized therapeutic trial of nitisinone in alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adult; Alkaptonuria; Cyclohexanones; Homogentisic Acid; Humans; Middle Aged; Nitrobenzoates; Prospective Studies; Tyrosine | 2011 |
31 other study(ies) available for tiletamine hydrochloride and Alkaptonuria
| Article | Year |
|---|---|
Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria.
Topics: Alkaptonuria; Brain Diseases, Metabolic, Inborn; Cyclohexanones; Homogentisic Acid; Humans; Nitrobenzoates; Phenylalanine; Phenylpropionates; Tyrosine; Tyrosinemias | 2022 |
[Alkaptonuria: Response to low-dose nitisinone in two patients with a new mutation].
Topics: Alkaptonuria; Cyclohexanones; Female; Humans; Male; Middle Aged; Mutation; Nitrobenzoates | 2022 |
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria.
Topics: Alkaptonuria; Animals; Cyclohexanones; Diet, Protein-Restricted; Female; Humans; Male; Mice; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias | 2020 |
Nitisinone causes acquired tyrosinosis in alkaptonuria.
Topics: Adult; Aged; Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Animals; Cyclohexanones; Female; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Nitrobenzoates; Phenylalanine; Tyrosine; Young Adult | 2020 |
Characterising the arthroplasty in spondyloarthropathy in a large cohort of eighty-seven patients with alkaptonuria.
Topics: Aged; Alkaptonuria; Arthroplasty; Cohort Studies; Cyclohexanones; Female; Humans; Linear Models; Male; Middle Aged; Nitrobenzoates; Ochronosis; Positron Emission Tomography Computed Tomography; Spondylarthropathies; United Kingdom | 2021 |
Characterizing the alkaptonuria joint and spine phenotype and assessing the effect of homogentisic acid lowering therapy in a large cohort of 87 patients.
Topics: Aged; Alkaptonuria; Cohort Studies; Cyclohexanones; Female; Homogentisic Acid; Humans; Joints; Linear Models; Male; Middle Aged; Nitrobenzoates; Ochronosis; Phenotype; Positron Emission Tomography Computed Tomography; Severity of Illness Index; Spine; United Kingdom | 2021 |
Evaluating the aortic stenosis phenotype before and after the effect of homogentisic acid lowering therapy: Analysis of a large cohort of eighty-one alkaptonuria patients.
Topics: Adult; Aged; Alkaptonuria; Aortic Valve Stenosis; Cohort Studies; Cyclohexanones; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitrobenzoates; Phenotype; Severity of Illness Index | 2021 |
Preventive use of nitisinone in alkaptonuria.
Topics: Alkaptonuria; Cyclohexanones; Humans; Nitrobenzoates; Tyrosine | 2021 |
Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone.
Topics: Adolescent; Adult; Aged; Alkaptonuria; Cyclohexanones; Depression; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nitrobenzoates; Tyrosine; Young Adult | 2018 |
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Cyclohexanones; Disease Progression; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Ochronosis; United Kingdom | 2018 |
A father's fight to help his sons - and fix clinical trials.
Topics: Adolescent; Alkaptonuria; Animals; Autopsy; Child; Clinical Trials as Topic; Compassionate Use Trials; Cyclohexanones; Disease Models, Animal; Disease Progression; Drug Approval; Endpoint Determination; Female; Homogentisic Acid; Humans; Infant; Male; Mice; National Health Programs; National Institutes of Health (U.S.); Nitrobenzoates; Observational Studies as Topic; Off-Label Use; Orphan Drug Production; Rare Diseases; Rats; Sample Size; Tyrosine; Tyrosinemias; United States; United States Food and Drug Administration | 2019 |
A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria.
Topics: Aged; Alkaptonuria; Animals; Chromatography, Liquid; Cyclohexanones; Databases, Chemical; Female; Gene Knockdown Techniques; Homogentisate 1,2-Dioxygenase; Humans; Male; Mass Spectrometry; Metabolome; Metabolomics; Mice; Middle Aged; Nitrobenzoates; Phenotype | 2019 |
Interference of hydroxyphenylpyruvic acid, hydroxyphenyllactic acid and tyrosine on routine serum and urine clinical chemistry assays; implications for biochemical monitoring of patients with alkaptonuria treated with nitisinone.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Cyclohexanones; Enzyme Inhibitors; Humans; Nitrobenzoates; Phenylpropionates; Phenylpyruvic Acids; Tyrosine | 2019 |
Efficacy of low dose nitisinone in the management of alkaptonuria.
Topics: Adult; Alkaptonuria; Child, Preschool; Cyclohexanones; Diet; Dose-Response Relationship, Drug; Female; Humans; Magnetic Resonance Spectroscopy; Male; Nitrobenzoates; Tyrosine; Young Adult | 2019 |
Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Chondrocytes; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Joint Diseases; Knee Joint; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrobenzoates; Ochronosis | 2014 |
Serum markers in alkaptonuria: simultaneous analysis of homogentisic acid, tyrosine and nitisinone by liquid chromatography tandem mass spectrometry.
Topics: Alkaptonuria; Biomarkers; Chromatography, Liquid; Cyclohexanones; Homogentisic Acid; Humans; Nitrobenzoates; Tandem Mass Spectrometry; Tyrosine | 2015 |
Perturbations of tyrosine metabolism promote the indolepyruvate pathway via tryptophan in host and microbiome.
Topics: Aldehydes; Alkaptonuria; Cell Line, Tumor; Cyclohexanones; Gastrointestinal Microbiome; Humans; Indoles; Mass Spectrometry; Metabolomics; Nitrobenzoates; Phenylpyruvic Acids; Symbiosis; Tryptophan; Tyrosine; Tyrosinemias | 2015 |
Osteoarticular cells tolerate short-term exposure to nitisinone-implications in alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Cell Line, Tumor; Chondrocytes; Cyclohexanones; Drug Evaluation, Preclinical; Humans; Nitrobenzoates; Osteoblasts | 2016 |
Progress in Alkaptonuria--are we near to an effective therapy?
Topics: Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Genetic Therapy; Humans; Mice; Nitrobenzoates; Ochronosis; Treatment Outcome | 2015 |
Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Cell Survival; Cyclohexanones; Dose-Response Relationship, Drug; Herbicides; Homogentisic Acid; Humans; Male; Molecular Structure; Nitrobenzoates; Rats; Rats, Wistar; Structure-Activity Relationship | 2016 |
A 54-year-old woman with arthritis and discoloration of the hands, ears, and sclerae.
Topics: Alkaptonuria; Arthroplasty, Replacement, Knee; Cyclohexanones; Diagnosis, Differential; Ear; Female; Hand; Humans; Middle Aged; Nitrobenzoates; Palliative Care; Pigmentation Disorders; Prognosis; Prosthesis Failure; Reoperation; Sclera; Severity of Illness Index | 2017 |
The effect of nitisinone on homogentisic acid and tyrosine: a two-year survey of patients attending the National Alkaptonuria Centre, Liverpool.
Topics: Adult; Aged; Alkaptonuria; Chromatography, Liquid; Cyclohexanones; Drug Administration Schedule; Enzyme Inhibitors; Female; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Longitudinal Studies; Male; Middle Aged; Monitoring, Physiologic; Nitrobenzoates; Tandem Mass Spectrometry; Tyrosine; United Kingdom | 2017 |
Alkaptonuria.
Topics: Aged; Alkaptonuria; Arthritis; Cyclohexanones; Female; Homogentisic Acid; Humans; Joint Diseases; Nitrobenzoates; Ochronosis; Pigmentation Disorders | 2010 |
A quantitative assessment of alkaptonuria: testing the reliability of two disease severity scoring systems.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Alkaptonuria; Causality; Cohort Studies; Comorbidity; Cyclohexanones; Female; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Hypertension; Male; Middle Aged; Nitrobenzoates; Ochronosis; Pain; Regression Analysis; Reproducibility of Results; Severity of Illness Index; Sex Distribution; Smoking; Surveys and Questionnaires | 2011 |
Natural history of alkaptonuria revisited: analyses based on scoring systems.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Adult; Aged; Aged, 80 and over; Alkaptonuria; Arthralgia; Arthritis; Cartilage, Articular; Causality; Cohort Studies; Comorbidity; Cyclohexanones; Disease Progression; Female; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Ochronosis; Pain; Surveys and Questionnaires | 2011 |
Alkaptonuria: treasure your exceptions.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Cyclohexanones; Humans; Nitrobenzoates; Therapies, Investigational | 2011 |
Natural history of alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Alkaptonuria; Child; Child, Preschool; Connective Tissue Diseases; Cyclohexanones; Dioxygenases; Disease Progression; DNA Mutational Analysis; Enzyme Inhibitors; Female; Heart Valve Diseases; Homogentisate 1,2-Dioxygenase; Humans; Joint Diseases; Kidney Calculi; Life Tables; Linear Models; Longitudinal Studies; Male; Middle Aged; Mutation; Nitrobenzoates; Oxygenases; Severity of Illness Index; Tyrosine | 2002 |
Alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Antioxidants; Ascorbic Acid; Benzoquinones; Cyclohexanones; Enzyme Inhibitors; Homogentisic Acid; Humans; Nitrobenzoates; Oxidation-Reduction | 2003 |
Use of nitisinone in patients with alkaptonuria.
Topics: Adult; Aged; Alkaptonuria; Cyclohexanones; Dietary Proteins; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Tyrosine | 2005 |
NTBC and alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Cyclohexanones; Enzyme Inhibitors; Humans; Nitrobenzoates; Tyrosine | 1998 |
A novel therapeutic trial of homogentisic aciduria in a murine model of alkaptonuria.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Homogentisic Acid; Mice; Mice, Mutant Strains; Nitrobenzoates | 1999 |