Page last updated: 2024-08-23

ticrynafen and Acute Liver Injury, Drug-Induced

ticrynafen has been researched along with Acute Liver Injury, Drug-Induced in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (48.72)	18.7374
1990's	11 (28.21)	18.2507
2000's	2 (5.13)	29.6817
2010's	7 (17.95)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Hattori, C; Jindo, T; Kai, K; Kataoka, H; Manabe, S; Masubuchi, N; Mori, K; Nishiya, T	1
Hattori, C; Jindo, T; Kataoka, H; Kato, M; Manabe, S; Maru, C; Mori, K; Nishiya, T; Suzuki, T; Tanaka, Y	1
Bergue, A; Eugène, C; Patriarche, C; Quevauvilliers, J	1
Homberg, JC	1
Abuaf, N; Andre, C; Homberg, JC	1
Darnis, F; Homberg, JC; Lafay, JP; Legendre, C; Poupon, R	1
Beg, M; Maass, AR; Snow, IB; Stote, RM	1
Beltaos, E; Chang, WW; Kirchner, JP; Manier, JW	1
O'Reilly, RA	1
Lobeck, H; Schumacher, R	1
André, C; Berthelot, P; Dhumeaux, D; Métreau, JM; Pariente, EA; Zafrani, ES	1
Beaugrand, M; Ferrier, JP; Gavillon, C	1
Bauch, W	1
Lakin, M	1
Abuaf, N; Bodin, F; Darnis, F; Homberg, JC; Petit, J; Poupon, R	1
Manns, MP; Straub, P; Van Pelt, FN	1
Beaune, P; Belloc, C; Bourdi, M; Gautier, JC; Guengerich, FP; Valadon, P	1
André, C; Beaune, PH; Lecoeur, S	1
Beaune, PH; Belloc, C; Gauffre, A; Gautier, JC; Lecoeur, S	1
Ballet, F; Bonierbale, E; Dansette, P; Le Breton, FP; Le Roy, M; Mansuy, D; Maratrat, M; Pessayre, D; Robin, MA	1
Beaune, PH; Belloc, C; Bourdi, M; Dansette, P; Gauffre, A; Lecoeur, S; Mansuy, D	1
Mansuy, D	2
Beaune, PH; Lecoeur, S	1
Wolfe, SM	1
Arbeille-Brassard, B; Chavanne, D; Groussin, P; Medelsi, M; Renard, JP; Royere, D	1
Biour, M; Chazouilleres, O; Giral, P; Housset, C; Poujol, A; Poupon, R	1
Pohl, LR	1
Neuberger, J; Williams, R	1
Amar, C; Beaune, P; Dansette, PM; Finck, M; Homberg, JC; Kiffel, L; Leroux, JP; Mansuy, D	1
Chousterman, M; Lam, X; Lebrec, D; Lechevalier, L	1

Reviews

7 review(s) available for ticrynafen and Acute Liver Injury, Drug-Induced

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Autoimmunity induced by drugs. Immunological characteristics and etiopathogenic hypotheses]. Presse medicale (Paris, France : 1983), 1984, Dec-15, Volume: 13, Issue:45 Topics: Animals; Autoimmune Diseases; Cardiac Glycosides; Chemical and Drug Induced Liver Injury; Drug Combinations; Humans; Iproniazid; Lymphocytes; Methimazole; Methyldopa; Penicillamine; Plant Extracts; Pyrazoles; T-Lymphocytes; Ticrynafen	1984
Molecular basis of drug-induced immunological liver injury. Seminars in liver disease, 1995, Volume: 15, Issue:3 Topics: Animals; Antibody Formation; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug-Related Side Effects and Adverse Reactions; Halothane; Haptens; Humans; Liver; Liver Diseases; Ticrynafen	1995
Anti-cytochrome P450 autoantibodies in drug-induced disease. European journal of haematology. Supplementum, 1996, Volume: 60 Topics: Autoantibodies; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dihydralazine; Humans; Ticrynafen	1996
Molecular structure and hepatotoxicity: compared data about two closely related thiophene compounds. Journal of hepatology, 1997, Volume: 26 Suppl 2 Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Diuretics; Humans; Liver; Stereoisomerism; Ticrynafen	1997
Immunotoxicology of the liver: adverse reactions to drugs. Journal of hepatology, 1997, Volume: 26 Suppl 2 Topics: Animals; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersensitivity; Halothane; Humans; Immunity; Ticrynafen	1997
Drug-induced allergic hepatitis. Seminars in liver disease, 1990, Volume: 10, Issue:4 Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Hepatitis, Alcoholic; Humans; Liver; Ticrynafen	1990

Other Studies

32 other study(ies) available for ticrynafen and Acute Liver Injury, Drug-Induced

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
The crucial protective role of glutathione against tienilic acid hepatotoxicity in rats. Toxicology and applied pharmacology, 2008, Oct-15, Volume: 232, Issue:2 Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutathione; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Ticrynafen	2008
Involvement of cytochrome P450-mediated metabolism in tienilic acid hepatotoxicity in rats. Toxicology letters, 2008, Dec-15, Volume: 183, Issue:1-3 Topics: Administration, Oral; Animals; Antihypertensive Agents; Apoptosis; Bile; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Gene Expression Profiling; Glutamate-Cysteine Ligase; Glutathione; Heme Oxygenase-1; Liver; Liver Diseases; Male; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tandem Mass Spectrometry; Ticrynafen; Up-Regulation	2008
[Tienilic acid as a likely cause of "auto immune" active hepatitis (author's transl)]. La Nouvelle presse medicale, 1980, Jun-21, Volume: 9, Issue:27 Topics: Aged; Anthraquinones; Autoimmune Diseases; Cathartics; Chemical and Drug Induced Liver Injury; Dioctyl Sulfosuccinic Acid; Drug Therapy, Combination; Female; Glycolates; Humans; Liver; Male; Middle Aged; Ticrynafen; Transaminases	1980
A new anti-liver-kidney microsome antibody (anti-LKM2) in tienilic acid-induced hepatitis. Clinical and experimental immunology, 1984, Volume: 55, Issue:3 Topics: Adolescent; Adult; Aged; Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Fluorescent Antibody Technique; Glycolates; Humans; Kidney; Liver Diseases; Male; Mice; Microsomes; Microsomes, Liver; Middle Aged; Rats; Retrospective Studies; Ticrynafen	1984
[Hepatic lesions associated with antimicrosomal antibodies of the liver and kidney (type 2) and the taking of tienilic acid. A study of 37 cases]. Gastroenterologie clinique et biologique, 1983, Volume: 7, Issue:5 Topics: Adult; Aged; Antibodies; Chemical and Drug Induced Liver Injury; Female; Glycolates; Humans; Jaundice; Kidney; Liver; Male; Microsomes; Microsomes, Liver; Middle Aged; Recurrence; Retrospective Studies; Ticrynafen; Time Factors	1983
Pharmacokinetics and mode of action of tienilic acid. Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:1-2 Topics: Acute Kidney Injury; Animals; Bile; Blood Pressure; Chemical and Drug Induced Liver Injury; Dogs; Female; Glycolates; Humans; Kidney; Kinetics; Male; Mice; Rats; Sex Factors; Ticrynafen; Tissue Distribution; Uric Acid	1982
Hepatotoxicity associated with ticrynafen--a uricosuric diuretic. The American journal of gastroenterology, 1982, Volume: 77, Issue:6 Topics: Adult; Chemical and Drug Induced Liver Injury; Glycolates; Humans; Liver; Liver Function Tests; Male; Ticrynafen; Uricosuric Agents	1982
Ticrynafen-racemic warfarin interaction: hepatotoxic or stereoselective? Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:3 Topics: Adult; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Interactions; Glycolates; Humans; Hypoprothrombinemias; Male; Prothrombin Time; Stereoisomerism; Ticrynafen; Warfarin	1982
[Cholestatic hepatitis with tienilic acid]. Die Medizinische Welt, 1981, Mar-20, Volume: 32, Issue:12 Topics: Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Glycolates; Humans; Male; Middle Aged; Ticrynafen	1981
[Tienilic acid can induce acute hepatitis, chronic hepatitis and cirrhosis. A report of three cases (author's transl)]. Gastroenterologie clinique et biologique, 1981, Volume: 5, Issue:5 Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Glycolates; Humans; Liver Cirrhosis; Middle Aged; Ticrynafen	1981
[Chronic hepatitis with elevated level of endoplasmic anti-reticulum antibodies: alpha-methyldopa or tienilic acid?]. Gastroenterologie clinique et biologique, 1981, Volume: 5, Issue:8-9 Topics: Chemical and Drug Induced Liver Injury; Female; Glycolates; Humans; Methyldopa; Ticrynafen	1981
Ticrynafen recalled. FDA drug bulletin, 1980, Volume: 10, Issue:1 Topics: Chemical and Drug Induced Liver Injury; Glycolates; Humans; Ticrynafen; United States	1980
[For instance Selacryn]. Die Medizinische Welt, 1980, Feb-15, Volume: 31, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Germany, West; Glycolates; Kidney Diseases; Legislation, Drug; Ticrynafen; United States	1980
Jogger's liver. The New England journal of medicine, 1980, 09-04, Volume: 303, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Hepatitis; Humans; Jogging; Male; Running; Ticrynafen	1980
[Tienilic acid-induced hepatitis associated with liver/kidney microsomal antibody (author's transl)]. La Nouvelle presse medicale, 1980, Jun-21, Volume: 9, Issue:27 Topics: Acute Disease; Adult; Autoantibodies; Chemical and Drug Induced Liver Injury; Chronic Disease; Endoplasmic Reticulum; Female; Glycolates; Humans; Kidney; Liver; Male; Microsomes; Microsomes, Liver; Middle Aged; Ticrynafen; Transaminases	1980
Immunotoxicology and expression of human cytochrome P450 in microorganisms. Toxicology, 1993, Oct-05, Volume: 82, Issue:1-3 Topics: Amino Acid Sequence; Animals; Autoantibodies; Bacteria; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dihydralazine; Humans; Microsomes, Liver; Molecular Sequence Data; Rabbits; Saccharomyces cerevisiae; Ticrynafen	1993
Tienilic acid-induced autoimmune hepatitis: anti-liver and-kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9. Molecular pharmacology, 1996, Volume: 50, Issue:2 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Autoantibodies; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Epitope Mapping; Humans; Infant; Rabbits; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Ticrynafen	1996
Use of heterologous expression systems to study autoimmune drug-induced hepatitis. Methods in enzymology, 1996, Volume: 272 Topics: Autoantibodies; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Escherichia coli; Gene Expression; Humans; In Vitro Techniques; Models, Biological; Recombinant Proteins; Saccharomyces cerevisiae; Ticrynafen	1996
Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera. The Journal of clinical investigation, 1996, Sep-15, Volume: 98, Issue:6 Topics: Alkylation; Animals; Autoantibodies; Biological Transport, Active; Cell Membrane; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Flow Cytometry; Immunoblotting; Liver; Male; Microscopy, Confocal; Microsomes, Liver; Precipitin Tests; Rats; Rats, Sprague-Dawley; Ticrynafen	1996
The marketing of a drug. Health & medicine : journal of the Health and Medicine Policy Research Group, 1982,Spring, Volume: 1, Issue:2 Topics: Chemical and Drug Induced Liver Injury; Drug Industry; Drug-Related Side Effects and Adverse Reactions; Humans; Hypertension; Jurisprudence; Product Surveillance, Postmarketing; Risk; Ticrynafen; United States; United States Food and Drug Administration	1982
[Cytolytic hepatitis, role of tienilic acid]. Medecine & chirurgie digestives, 1979, Volume: 8, Issue:5 Topics: Aged; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Glycolates; Humans; Jaundice; Male; Ticrynafen	1979
Fulminant hepatitis due to tienilic acid. Lancet (London, England), 1991, Oct-05, Volume: 338, Issue:8771 Topics: Chemical and Drug Induced Liver Injury; Humans; Hypertension; Male; Middle Aged; Ticrynafen	1991
Formation of reactive metabolites and appearance of anti-organelle antibodies in man. Advances in experimental medicine and biology, 1991, Volume: 283 Topics: Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Humans; Mitochondria, Liver; Monoamine Oxidase; Organelles; Ticrynafen; Xenobiotics	1991
Immune mechanisms in tienilic acid associated hepatotoxicity. Gut, 1989, Volume: 30, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antibody-Dependent Cell Cytotoxicity; Chemical and Drug Induced Liver Injury; Female; Glycolates; Humans; Male; Middle Aged; Ticrynafen	1989
Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug. Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:2 Topics: Adult; Autoantibodies; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Female; Glycolates; Humans; Hydroxylation; Kidney Transplantation; Microsomes, Liver; Ticrynafen	1987
[Fulminating hepatitis caused by tienilic acid]. Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:3 Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Glycolates; Humans; Ticrynafen	1987