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ticlopidine and Ventricular Dysfunction, Left

ticlopidine has been researched along with Ventricular Dysfunction, Left in 15 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Research Excerpts

ExcerptRelevanceReference
"In the current era of early revascularization and routine use of dual antiplatelet therapy, the incremental benefit of warfarin to reduce the incidence of left ventricular thrombus (LVT) in patients with impaired left ventricular ejection fraction post anterior ST-elevation myocardial infarction (aSTEMI), remains uncertain."9.14Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: a randomized feasibility trial. ( Ahmad, M; Eikelboom, JW; Natarajan, MK; Salehian, O; Schwalm, JD, 2010)
"Participants in the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE) trials with HF, but not randomized to oral anticoagulation, were categorized as having preserved versus reduced ejection fraction."5.20Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure. ( Connolly, SJ; Hart, RG; Healey, JS; Hohnloser, SH; McAlister, FA; Pfeffer, MA; Sandhu, RK; Yuan, F; Yusuf, S, 2015)
"In the current era of early revascularization and routine use of dual antiplatelet therapy, the incremental benefit of warfarin to reduce the incidence of left ventricular thrombus (LVT) in patients with impaired left ventricular ejection fraction post anterior ST-elevation myocardial infarction (aSTEMI), remains uncertain."5.14Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: a randomized feasibility trial. ( Ahmad, M; Eikelboom, JW; Natarajan, MK; Salehian, O; Schwalm, JD, 2010)
"Chronic myocardial ischemia was induced using a minimally invasive model in 16 landrace pigs."1.37Gene therapy with iNOS enhances regional contractility and reduces delayed contrast enhancement in a model of postischemic congestive heart failure. ( Abegunewardene, N; Gori, T; Horstick, G; Kreitner, KF; Lehr, HA; Münzel, T; Schmidt, KH; Schreiber, LM; Vosseler, M, 2011)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's9 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lanzillo, C1
Di Roma, M1
Sciahbasi, A1
Minati, M1
Maresca, L1
Pendenza, G1
Romagnoli, E1
Summaria, F1
Patrizi, R1
Di Luozzo, M1
Preziosi, P1
Lioy, E1
Romeo, F1
Blancas Gómez-Casero, R1
Quintana Díaz, M1
Chana García, M1
Martín Parra, C1
López Matamala, B1
Estébanez Montiel, B1
Ballesteros Ortega, D1
Martínez González, O1
Vigil Escribano, D1
Prieto Valderrey, F1
Marina Martínez, L1
Castro Gallego, O1
Motovska, Z1
Ondrakova, M1
Doktorova, M1
Widimsky, P1
Sandhu, RK1
Hohnloser, SH1
Pfeffer, MA1
Yuan, F1
Hart, RG1
Yusuf, S1
Connolly, SJ1
McAlister, FA1
Healey, JS1
Nakashima, K1
Kirsch, ME1
Vermes, E1
Rosanval, O1
Loisance, D1
Schwalm, JD1
Ahmad, M1
Salehian, O1
Eikelboom, JW1
Natarajan, MK1
Lemesle, G1
Delhaye, C1
Abegunewardene, N1
Schmidt, KH1
Vosseler, M1
Kreitner, KF1
Schreiber, LM1
Lehr, HA1
Gori, T1
Münzel, T1
Horstick, G1
El-Menyar, A1
AlHabib, KF1
Al-Motarreb, A1
Hersi, A1
Al Faleh, H1
Asaad, N1
Al Saif, S1
Almahmeed, W1
Sulaiman, K1
Amin, H1
Al-Lawati, J1
Alsheikh-Ali, AA1
AlQahtani, A1
Al-Sagheer, NQ1
Singh, R1
Al Suwaidi, J1
Swiatkiewicz, I1
Kozinski, M1
Magielski, P1
Gierach, J1
Fabiszak, T1
Kubica, A1
Sukiennik, A1
Navarese, EP1
Odrowaz-Sypniewska, G1
Kubica, J1
Davutoglu, V1
Soydinc, S1
Sezen, Y1
Wienbergen, H1
Gitt, AK1
Schiele, R1
Juenger, C1
Heer, T1
Vogel, C1
Gottwik, M1
Senges, J1
Goldberg, SL1
Kuchulakanti, P1
Kapetanakis, EI1
Lew, R1
Rha, SW1
Cheneau, E1
Satler, LF1
Suddath, WO1
Pichard, AD1
Kent, KM1
Pakala, R1
Haile, E1
Corso, P1
Waksman, R1
Horwich, TB1
Fonarow, GC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Laboratory AntiPlatelet Efficacy and Clinical Outcome Registry[NCT02264912]2,016 participants (Actual)Observational [Patient Registry]2008-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ticlopidine and Ventricular Dysfunction, Left

ArticleYear
[Decreasing incidence of stent thrombosis].
    Annales de cardiologie et d'angeiologie, 2011, Volume: 60, Issue:6

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Drug Therap

2011
Prevention of heart failure.
    Current cardiology reports, 2002, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Ant

2002

Trials

2 trials available for ticlopidine and Ventricular Dysfunction, Left

ArticleYear
Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure.
    Stroke, 2015, Volume: 46, Issue:3

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopid

2015
Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: a randomized feasibility trial.
    Journal of thrombosis and thrombolysis, 2010, Volume: 30, Issue:2

    Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Embolism; Feasibility Studies

2010

Other Studies

11 other studies available for ticlopidine and Ventricular Dysfunction, Left

ArticleYear
Cardiac magnetic resonance detection of left ventricular thrombus in acute myocardial infarction.
    Acute cardiac care, 2013, Volume: 15, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Echocardiogra

2013
[Influence of the combination of antiplatelet agents on the occurrence of early left ventricular insufficiency in patients with acute coronary syndromes without persistent ST-segment elevation].
    Medicina clinica, 2014, Apr-07, Volume: 142, Issue:7

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; F

2014
Severe left ventricular systolic dysfunction is independently associated with high on-clopidogrel platelet reactivity.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Female; Humans

2014
Off-pump replacement of the INCOR implantable axial-flow pump.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:2

    Topics: Anticoagulants; Aspirin; Clopidogrel; Equipment Design; Heart-Assist Devices; Humans; Infusion Pumps

2009
Gene therapy with iNOS enhances regional contractility and reduces delayed contrast enhancement in a model of postischemic congestive heart failure.
    Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4

    Topics: Animals; Anticoagulants; Aspirin; Clopidogrel; Contrast Media; Coronary Angiography; Coronary Stenos

2011
Prior antiplatelet use and cardiovascular outcomes in patients presenting with acute coronary syndromes.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012, Apr-01, Volume: 12, Issue:2

    Topics: Acute Coronary Syndrome; Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug The

2012
Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Antihypertensive Agents; Aspirin; Biom

2012
Complete lysis of left ventricular giant thrombus with fibrinolytic therapy in clopidogrel resistant patient.
    Journal of thrombosis and thrombolysis, 2003, Volume: 15, Issue:1

    Topics: Clopidogrel; Drug Resistance; Electrocardiography; Female; Humans; Middle Aged; Thrombolytic Therapy

2003
Different treatments and outcomes of consecutive patients with non-ST-elevation myocardial infarction depending on initial electrocardiographic changes (results of the Acute Coronary Syndromes [ACOS] Registry).
    The American journal of cardiology, 2004, Jun-15, Volume: 93, Issue:12

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angioplasty, Balloon, Coronary; Angiotensin-Converti

2004
Why don't we practice evidence-based medicine?
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:1

    Topics: Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Evidence-Based M

2005
Impact of continued hospitalization in patients pre-treated with clopidogrel prior to coronary angiography and undergoing coronary artery bypass grafting.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:1

    Topics: Aged; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Female; Ho

2005