Page last updated: 2024-11-05

ticlopidine and Uremia

ticlopidine has been researched along with Uremia in 6 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Dialysis did not affect the antiplatelet effects of aspirin and clopidogrel in uremic patients with coronary heart disease."3.85Effect of Dialysis on Antiplatelet Drug Efficacy in Uremic Patients with Coronary Heart Disease. ( Fu, DL; Gao, YX; Li, XL; Liu, XF; Lu, HK; Peng, WH; Wang, Q; Wang, Y; Yang, P; Zhang, H; Zhao, TT; Zheng, JG, 2017)
"Ticlopidine was administered by gavage at a dose of 50 mg/kg/day starting 72 hr prior to hemodialysis and continuing throughout the period of hemodialysis (4 days)."1.26A comparison of ticlopidine and heparin on hemodialysis in dogs. ( Bush, H; Flamenbaum, W; Gross, ML; Hamburger, RJ; Weinger, R, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fu, DL1
Zhao, TT1
Peng, WH1
Yang, P1
Liu, XF1
Zhang, H1
Li, XL1
Wang, Y1
Zheng, JG1
Gao, YX1
Lu, HK1
Wang, Q1
Basra, SS1
Tsai, P1
Lakkis, NM1
Gross, ML1
Bush, H1
Weinger, R1
Hamburger, RJ1
Flamenbaum, W1
Milutinović, S1
Gasparović, V1
Milutinović, E1
Buturović-Ponikvar, J1
Caravaca, F1
López-Minguez, JR1
Arrobas, M1
Cubero, J1
Pizarro, JL1
Cid, MC1
Sanchez-Casado, E1
Miranda, MP1
Gröntoft, KC1
Larsson, R1
Mulec, H1
Weiss, LG1
Dickinson, JP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Platelet Aggregation and Adenosine Levels in Patients With Coronary Artery Disease and Chronic Kidney Dysfunction Taking Dual Antiplatelet Therapy With Aspirin and Clopidogrel or Ticagrelor[NCT03039205]Phase 290 participants (Actual)Interventional2017-11-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ticlopidine and Uremia

ArticleYear
Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.
    Journal of the American College of Cardiology, 2011, Nov-22, Volume: 58, Issue:22

    Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chronic Disease; Clinical Trials as Topic; Clopidogrel;

2011

Trials

3 trials available for ticlopidine and Uremia

ArticleYear
Ticlopidine improves dialysis clearance of solutes in uremic patients by reducing blood clotting in dialyser fibers.
    The International journal of artificial organs, 1993, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Coagulation; Creatinine; Double-Blind Method; Femal

1993
Haemodynamic changes induced by the correction of anaemia by erythropoietin: role of antiplatelet therapy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1995, Volume: 10, Issue:9

    Topics: Adult; Aged; Anemia; Aspirin; Dipyridamole; Erythropoietin; Female; Hemodynamics; Humans; Male; Midd

1995
Effects of ticlopidine in AV-fistula surgery in uremia. Fistula Study Group.
    Scandinavian journal of urology and nephrology, 1998, Volume: 32, Issue:4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis Implantation; Double-Blind Metho

1998

Other Studies

2 other studies available for ticlopidine and Uremia

ArticleYear
Effect of Dialysis on Antiplatelet Drug Efficacy in Uremic Patients with Coronary Heart Disease.
    Chinese medical journal, 2017, Aug-20, Volume: 130, Issue:16

    Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Platelet Aggregatio

2017
A comparison of ticlopidine and heparin on hemodialysis in dogs.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:6

    Topics: Animals; Anorexia; Diarrhea; Dogs; Heparin; Renal Dialysis; Thiophenes; Ticlopidine; Uremia

1982