ticlopidine has been researched along with Uremia in 6 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dialysis did not affect the antiplatelet effects of aspirin and clopidogrel in uremic patients with coronary heart disease." | 3.85 | Effect of Dialysis on Antiplatelet Drug Efficacy in Uremic Patients with Coronary Heart Disease. ( Fu, DL; Gao, YX; Li, XL; Liu, XF; Lu, HK; Peng, WH; Wang, Q; Wang, Y; Yang, P; Zhang, H; Zhao, TT; Zheng, JG, 2017) |
| "Ticlopidine was administered by gavage at a dose of 50 mg/kg/day starting 72 hr prior to hemodialysis and continuing throughout the period of hemodialysis (4 days)." | 1.26 | A comparison of ticlopidine and heparin on hemodialysis in dogs. ( Bush, H; Flamenbaum, W; Gross, ML; Hamburger, RJ; Weinger, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, DL | 1 |
| Zhao, TT | 1 |
| Peng, WH | 1 |
| Yang, P | 1 |
| Liu, XF | 1 |
| Zhang, H | 1 |
| Li, XL | 1 |
| Wang, Y | 1 |
| Zheng, JG | 1 |
| Gao, YX | 1 |
| Lu, HK | 1 |
| Wang, Q | 1 |
| Basra, SS | 1 |
| Tsai, P | 1 |
| Lakkis, NM | 1 |
| Gross, ML | 1 |
| Bush, H | 1 |
| Weinger, R | 1 |
| Hamburger, RJ | 1 |
| Flamenbaum, W | 1 |
| Milutinović, S | 1 |
| Gasparović, V | 1 |
| Milutinović, E | 1 |
| Buturović-Ponikvar, J | 1 |
| Caravaca, F | 1 |
| López-Minguez, JR | 1 |
| Arrobas, M | 1 |
| Cubero, J | 1 |
| Pizarro, JL | 1 |
| Cid, MC | 1 |
| Sanchez-Casado, E | 1 |
| Miranda, MP | 1 |
| Gröntoft, KC | 1 |
| Larsson, R | 1 |
| Mulec, H | 1 |
| Weiss, LG | 1 |
| Dickinson, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Platelet Aggregation and Adenosine Levels in Patients With Coronary Artery Disease and Chronic Kidney Dysfunction Taking Dual Antiplatelet Therapy With Aspirin and Clopidogrel or Ticagrelor[NCT03039205] | Phase 2 | 90 participants (Actual) | Interventional | 2017-11-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ticlopidine and Uremia
| Article | Year |
|---|---|
Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chronic Disease; Clinical Trials as Topic; Clopidogrel; | 2011 |
3 trials available for ticlopidine and Uremia
| Article | Year |
|---|---|
Ticlopidine improves dialysis clearance of solutes in uremic patients by reducing blood clotting in dialyser fibers.
Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Coagulation; Creatinine; Double-Blind Method; Femal | 1993 |
Haemodynamic changes induced by the correction of anaemia by erythropoietin: role of antiplatelet therapy.
Topics: Adult; Aged; Anemia; Aspirin; Dipyridamole; Erythropoietin; Female; Hemodynamics; Humans; Male; Midd | 1995 |
Effects of ticlopidine in AV-fistula surgery in uremia. Fistula Study Group.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis Implantation; Double-Blind Metho | 1998 |
2 other studies available for ticlopidine and Uremia
| Article | Year |
|---|---|
Effect of Dialysis on Antiplatelet Drug Efficacy in Uremic Patients with Coronary Heart Disease.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Platelet Aggregatio | 2017 |
A comparison of ticlopidine and heparin on hemodialysis in dogs.
Topics: Animals; Anorexia; Diarrhea; Dogs; Heparin; Renal Dialysis; Thiophenes; Ticlopidine; Uremia | 1982 |