Page last updated: 2024-11-05

ticlopidine and Reperfusion Injury

ticlopidine has been researched along with Reperfusion Injury in 9 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
" In this study, we aimed to assess the effects of clopidogrel, an antithrombotic agent, on experimental ischemia-reperfusion model in rats."7.73Protective effects of clopidogrel on oxidant damage in a rat model of acute ischemia. ( Akbas, MH; Berki, KT; Bulbul, S; Kanko, M; Maral, H; Omay, O; Ozden, M; Yavuz, S, 2005)
" In this study, we aimed to assess the effects of clopidogrel, an antithrombotic agent, on experimental ischemia-reperfusion model in rats."3.73Protective effects of clopidogrel on oxidant damage in a rat model of acute ischemia. ( Akbas, MH; Berki, KT; Bulbul, S; Kanko, M; Maral, H; Omay, O; Ozden, M; Yavuz, S, 2005)
"Here we found that renal ischemia reperfusion injury in mice leads to increased platelet activation in immediate proximity of necrotic cell casts."1.46Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps. ( Dessing, MC; Emal, D; Florquin, S; Jansen, MP; Roelofs, JJ; Teske, GJ, 2017)
"Ischemia and reperfusion injury is a pathologic process with serious consequences, arising due to interruption of arterial blood flow."1.33Effect of clopidogrel on nitric oxide levels in an ischemia reperfusion model. ( Acil, C; Kanko, M; Maral, H; Ozden, M, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kwong, W1
Parker, JD1
Weisshaar, S1
Litschauer, B1
Eipeldauer, M1
Hobl, EL1
Wolzt, M1
Amagase, K1
Yoshida, Y1
Hara, D1
Murakami, T1
Takeuchi, K1
Silber, T1
Ziemann, U1
Ernemann, U1
Bischof, F1
Demirtas, S1
Karahan, O1
Yazıcı, S1
Guclu, O1
Calıskan, A1
Tezcan, O1
Kaplan, I1
Yavuz, C1
Jansen, MP1
Emal, D1
Teske, GJ1
Dessing, MC1
Florquin, S1
Roelofs, JJ1
Hu, H1
Batteux, F1
Chéreau, C1
Kavian, N1
Marut, W1
Gobeaux, C1
Borderie, D1
Dinh-Xuan, AT1
Weill, B1
Nicco, C1
Kanko, M2
Maral, H2
Akbas, MH1
Ozden, M2
Bulbul, S1
Omay, O1
Yavuz, S1
Berki, KT1
Acil, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double - Blind, Placebo - Controlled Trial to Investigate the Effect of Dapagliflozin on Ischemia Reperfusion Induced Endothelial Dysfunction of the Forearm Vasculature in Healthy Male Subjects[NCT05217654]Phase 132 participants (Anticipated)Interventional2022-02-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for ticlopidine and Reperfusion Injury

ArticleYear
The Effect of Clopidogrel on the Response to Ischemia Reperfusion.
    Journal of cardiovascular pharmacology and therapeutics, 2017, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Chemokine CCL5; Clopidogrel; Endothelium, Vascular; Female; Healthy V

2017
Ticagrelor mitigates ischaemia-reperfusion induced vascular endothelial dysfunction in healthy young males - a randomized, single-blinded study.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:12

    Topics: Adenosine; Administration, Oral; Adolescent; Adult; Austria; Blood Flow Velocity; Clopidogrel; Drug

2017

Other Studies

7 other studies available for ticlopidine and Reperfusion Injury

ArticleYear
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:1

    Topics: Animals; Aspirin; Azulenes; Benzoquinones; Clopidogrel; Gastric Mucosa; Gastrointestinal Hemorrhage;

2013
Analysis of periinterventional complications of intracranial angioplasty and stenting: a single center experience.
    European journal of radiology, 2014, Volume: 83, Issue:12

    Topics: Aged; Angioplasty; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Diabetes Complication

2014
Investigation of possible prophylactic, renoprotective, and cardioprotective effects of thromboprophylactic drugs against ischemia-reperfusion injury.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:3

    Topics: Animals; Anticoagulants; Aryldialkylphosphatase; Aspirin; Cardiotonic Agents; Clopidogrel; Dipeptida

2015
Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps.
    Kidney international, 2017, Volume: 91, Issue:2

    Topics: Animals; Blood Platelets; Cell Line; Clopidogrel; Disease Models, Animal; DNA; Epithelial Cells; Ext

2017
Clopidogrel protects from cell apoptosis and oxidative damage in a mouse model of renal ischaemia-reperfusion injury.
    The Journal of pathology, 2011, Volume: 225, Issue:2

    Topics: Animals; Apoptosis; Clopidogrel; Disease Models, Animal; Fluorescent Antibody Technique; Immunoblott

2011
Protective effects of clopidogrel on oxidant damage in a rat model of acute ischemia.
    The Tohoku journal of experimental medicine, 2005, Volume: 205, Issue:2

    Topics: Animals; Clopidogrel; Disease Models, Animal; Glutathione; Ischemia; Male; Malondialdehyde; Oxidants

2005
Effect of clopidogrel on nitric oxide levels in an ischemia reperfusion model.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:1

    Topics: Animals; Clopidogrel; Disease Models, Animal; Intubation, Gastrointestinal; Liver; Lung; Muscle, Ske

2006