ticlopidine has been researched along with Purpura, Thrombotic Thrombocytopenic in 92 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Purpura, Thrombotic Thrombocytopenic: An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of the most unusual causes of thrombotic thrombocytopenic purpura (TTP), a life-threatening disease, is ticlopidine hydrochloride, an antiplatelet agent used to prevent strokes in high-risk populations or following coronary artery stent placement." | 8.80 | Thrombotic thrombocytopenic purpura associated with ticlopidine in the setting of coronary artery stents and stroke prevention. ( Bennett, CL; Bennett, RH; Davidson, CJ; Feldman, MD; Raisch, DW; Weinberg, PD, 1999) |
| "A cerebral hemorrhage was the first sign of the thrombocytopenia." | 5.28 | Cerebral hemorrhage and thrombotic thrombocytopenic purpura during ticlopidine treatment: case report. ( Capra, R; Capucci, M; Ferremi, P; Fieni, F; Marcianò, N; Orlandini, A, 1992) |
| "Clinicians will be able to understand the safety profile of using different doses of clopidogrel and the incidence of bleeding when used alone or in combination with other antiplatelet agents." | 4.87 | The safety of clopidogrel. ( Kleiman, NS; Mangalpally, KK, 2011) |
| "One of the most unusual causes of thrombotic thrombocytopenic purpura (TTP), a life-threatening disease, is ticlopidine hydrochloride, an antiplatelet agent used to prevent strokes in high-risk populations or following coronary artery stent placement." | 4.80 | Thrombotic thrombocytopenic purpura associated with ticlopidine in the setting of coronary artery stents and stroke prevention. ( Bennett, CL; Bennett, RH; Davidson, CJ; Feldman, MD; Raisch, DW; Weinberg, PD, 1999) |
| "We report a 50-year-old man who presented with acute myocardial infarction and received clopidogrel therapy." | 3.77 | [Clopidogrel induced thrombotic thrombocytopenic purpura]. ( Coppérré, B; Hot, A; Karkowski, L; Lescampf, J; Ninet, J; Veyradier, A; Wolf, M, 2011) |
| "Our study shows that thrombotic thrombocytopenic purpura is a heterogeneous syndrome, and that features of the disease at presentation are strongly associated with the mechanisms of ADAMTS13 deficiency." | 2.82 | Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy. ( Azoulay, E; Benhamou, Y; Boisseau, P; Coppo, P; de Maistre, E; Delmas, Y; Galicier, L; Mariotte, E; Perez, P; Poullin, P; Provôt, F; Rondeau, E; Stepanian, A; Veyradier, A; Zouiti, F, 2016) |
| "Hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP), and several other conditions are associated with TMA." | 2.44 | The thrombotic microangiopathies. ( Copelovitch, L; Kaplan, BS, 2008) |
| "Ticlopidine is an antiplatelet agent that interferes with platelet membrane function by inhibiting adenosine diphosphate-induced platelet activation." | 2.43 | [Clinical features and laboratory findings of thrombotic thrombocytopenic purpura associated with ticlopidine]. ( Yagi, H, 2005) |
| "Drug-associated thrombotic thrombocytopenic purpura and hemolytic uremic syndrome (TTP/HUS) has been recognized for several years." | 2.43 | Drug-induced thrombotic microangiopathy. ( Bennett, C; Zakarija, A, 2005) |
| "Ticlopidine therapy is an important risk factor for TTP." | 2.41 | Thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. ( Baker, KR; Moake, JL, 2000) |
| "We describe a case of thrombotic thrombocytopenic purpura associated with the use of clopidogrel after percutaneous transluminal angioplasty and stent placement." | 2.41 | Thrombotic thrombocytopenic purpura associated with clopidogrel administration: case report and brief review. ( Ashley, I; Nara, W; Rosner, F, 2001) |
| "Ticlopidine is an antiplatelet agent that is used to reduce the occurrence of atherothrombotic arterial events." | 2.40 | Adverse haematological effects of ticlopidine. Prevention, recognition and management. ( Biller, J; Gent, M; Love, BB, 1998) |
| "Ticlopidine hydrochloride is an antiplatelet agent used for an increasing number of indications, including cerebrovascular disease, unstable angina, coronary artery stenting, and peripheral vascular bypass grafting." | 2.40 | Thrombotic thrombocytopenic purpura associated with ticlopidine use: a report of 3 cases and review of the literature. ( Chen, DK; Kim, JS; Sutton, DM, 1999) |
| "Thrombotic thrombocytopenic purpura is a rare complication of thienopyridine treatment." | 1.34 | Two mechanistic pathways for thienopyridine-associated thrombotic thrombocytopenic purpura: a report from the SERF-TTP Research Group and the RADAR Project. ( Bandarenko, N; Bennett, CL; Buffie, CG; Cursio, JF; Davidson, C; De Masi, D; Fujimura, Y; Kato, S; Kim, B; Kiss, JE; Kwaan, HC; Matsumoto, M; McKoy, JM; Ortel, TL; Pandey, DK; Raife, TJ; Raisch, DW; Sadler, JE; Sarode, R; Tevar, AD; Uemura, M; Yarnold, PR; Zakarija, A; Zheng, XL, 2007) |
| "We reported a Japanese first case of thrombotic thrombocytopenic purpura (TTP) induced by clopidogrel, a newly developed antithrombotic drug, marketed in May 2006 in Japan." | 1.34 | [Case of thrombotic thrombocytopenic purpura associated with clopidogrel]. ( Fujimura, Y; Fukusako, T; Matsuda, K; Omoto, M; Shinohara, K; Yamashita, H, 2007) |
| "A 69-year-old man of thrombotic thrombocytopenic purpura (TTP) associated with ticlopidine was reported." | 1.33 | [A case of ticlopidine-associated thrombotic thrombocytopenic purpura: special emphasis on diffusion weighted MRI]. ( Endo, K; Matsuda, N; Matsuda, T; Nishikata, R; Yamamoto, T; Yoshihara, A, 2006) |
| "Thrombotic thrombocytopenic purpura is a syndrome characterized by hemolytic anemia, thrombocytopenia, neurological symptoms, fever and renal dysfunction." | 1.32 | Thrombotic thrombocytopenic purpura associated with ticlopidine. ( Kandemir, G; Orhan, B; Oztürk, A; Türken, O; Yaylaci, M, 2003) |
| "Eleven cases of thrombotic thrombocytopenic purpura (TTP) associated with clopidogrel therapy have been published." | 1.31 | Thrombotic thrombocytopenic purpura associated with clopidogrel: further evaluation. ( Cohen, EA; Lanctôt, KL; Papastergiou, J; Paradiso-Hardy, FL, 2002) |
| "Only in a few case reports the thrombotic thrombocytopenic purpura was related to ticlopidine with a controversial discussion about this association." | 1.31 | [Thrombotic thrombocytopenic purpura (Moschkowitz-syndrome) caused by ticlopidine]. ( Chemnitz, JM; Diehl, V; Draube, A; Müller, R; Salameh, A; Scheid, C; Schulz, A; Söhngen, D, 2000) |
| "We present a case report of thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) developing in a kidney/pancreas transplant recipient after the initiation of treatment with clopidogrel for symptomatic coronary artery disease." | 1.31 | Clopidogrel-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in a kidney/pancreas transplant recipient. ( Chinnakotla, S; Fidler, ME; Hammeke, MD; Leone, JP; Tarantolo, S, 2000) |
| "A clinical diagnosis of thrombotic thrombocytopenic purpura (TTP) was made." | 1.30 | A case of dermatomyositis complicated by thrombotic thrombocytopenic purpura. ( Arase, S; Horie, T; Miyaoka, Y; Nameda, Y; Sano, N; Shigekiyo, T; Urano, Y, 1997) |
| "Instances of ticlopidine-associated thrombotic thrombocytopenic purpura were identified." | 1.30 | Thrombotic thrombocytopenic purpura associated with ticlopidine. A review of 60 cases. ( Bennett, CL; Green, D; Kwaan, HC; Rozenberg-Ben-Dror, K; Weinberg, PD; Yarnold, PR, 1998) |
| "Ticlopidine has been reported as causing neutropenia and isolated thrombocytopenia." | 1.29 | Thrombotic thrombocytopenic purpura associated with ticlopidine. ( Chin-Yee, IH; Kovacs, MJ; Soong, PY, 1993) |
| "A cerebral hemorrhage was the first sign of the thrombocytopenia." | 1.28 | Cerebral hemorrhage and thrombotic thrombocytopenic purpura during ticlopidine treatment: case report. ( Capra, R; Capucci, M; Ferremi, P; Fieni, F; Marcianò, N; Orlandini, A, 1992) |
| "In 2 ticlopidine was the only medication taken before TTP; in another, rechallenge with drugs other than ticlopidine that the patient had been taking did not produce relapse." | 1.28 | Thrombotic thrombocytopenic purpura related to ticlopidine. ( Bertrand, JC; Comtet, C; Page, Y; Tardy, B; Terrana, R; Zeni, F, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.26) | 18.7374 |
| 1990's | 29 (31.52) | 18.2507 |
| 2000's | 50 (54.35) | 29.6817 |
| 2010's | 9 (9.78) | 24.3611 |
| 2020's | 1 (1.09) | 2.80 |
| Authors | Studies |
|---|---|
| Ndulue, CN | 1 |
| Jisieike-Onuigbo, NN | 1 |
| Okwesa, NJ | 1 |
| Anyanor, A | 1 |
| Ozuemba, BC | 1 |
| Osakwe, N | 1 |
| Oguejiofor, F | 1 |
| Eze, H | 1 |
| Kalu, AO | 1 |
| Odenigbo, CU | 1 |
| Bennett, CL | 11 |
| Jacob, S | 2 |
| Dunn, BL | 2 |
| Georgantopoulos, P | 1 |
| Zheng, XL | 4 |
| Kwaan, HC | 8 |
| McKoy, JM | 5 |
| Magwood, JS | 1 |
| Qureshi, ZP | 2 |
| Bandarenko, N | 5 |
| Winters, JL | 3 |
| Raife, TJ | 5 |
| Carey, PM | 2 |
| Sarode, R | 5 |
| Kiss, JE | 4 |
| Danielson, C | 2 |
| Ortel, TL | 4 |
| Clark, WF | 2 |
| Ablin, RJ | 1 |
| Rock, G | 2 |
| Matsumoto, M | 7 |
| Fujimura, Y | 8 |
| Cavalli, G | 1 |
| Sallemi, C | 1 |
| Berti, A | 1 |
| Ferrari, B | 1 |
| Cairo, A | 1 |
| Pontiggia, S | 1 |
| Mancini, I | 1 |
| Masini, L | 1 |
| Peyvandi, F | 1 |
| Khodor, S | 1 |
| Castro, M | 1 |
| McNamara, C | 1 |
| Chaulagain, CP | 1 |
| Mariotte, E | 1 |
| Azoulay, E | 1 |
| Galicier, L | 1 |
| Rondeau, E | 1 |
| Zouiti, F | 1 |
| Boisseau, P | 1 |
| Poullin, P | 1 |
| de Maistre, E | 1 |
| Provôt, F | 1 |
| Delmas, Y | 1 |
| Perez, P | 1 |
| Benhamou, Y | 1 |
| Stepanian, A | 1 |
| Coppo, P | 1 |
| Veyradier, A | 2 |
| Ito, Y | 1 |
| Hashimoto, Y | 1 |
| Zakarija, A | 4 |
| Moake, JL | 4 |
| Pandey, DK | 4 |
| Yarnold, PR | 4 |
| Raisch, DW | 5 |
| Cursio, JF | 3 |
| Luu, TH | 1 |
| Richey, EA | 1 |
| Fisher, MJ | 1 |
| Tallman, MS | 1 |
| Wojciechowska, M | 1 |
| Grzywanowska-Łaniewska, I | 1 |
| Załeska-Zydlewska, I | 1 |
| Dłuzniewski, M | 1 |
| Yoshii, F | 1 |
| Mangalpally, KK | 1 |
| Kleiman, NS | 1 |
| Karkowski, L | 1 |
| Wolf, M | 1 |
| Lescampf, J | 1 |
| Coppérré, B | 1 |
| Ninet, J | 1 |
| Hot, A | 1 |
| Ishikawa, T | 1 |
| Makita, M | 1 |
| Saeki, K | 1 |
| Hara, Y | 1 |
| Yamamoto, K | 1 |
| Imajo, K | 1 |
| Barnato, SE | 1 |
| Weiss, I | 1 |
| Chen, H | 1 |
| Chen, F | 1 |
| Armstrong, JM | 1 |
| Paradiso-Hardy, FL | 1 |
| Papastergiou, J | 1 |
| Lanctôt, KL | 1 |
| Cohen, EA | 1 |
| Griffiths, C | 1 |
| Fisher, M | 1 |
| Evens, AM | 1 |
| Kaufman, DB | 1 |
| Türken, O | 1 |
| Oztürk, A | 1 |
| Orhan, B | 1 |
| Kandemir, G | 1 |
| Yaylaci, M | 1 |
| Yang, CW | 2 |
| Chen, YC | 2 |
| Dunn, P | 2 |
| Chang, MY | 2 |
| Fang, JT | 2 |
| Huang, CC | 2 |
| Majhail, NS | 1 |
| Lichtin, AE | 1 |
| Mauro, M | 2 |
| Zlatopolskiy, A | 1 |
| Laurence, J | 2 |
| Auerbach, A | 1 |
| Kim, B | 2 |
| Schmitt, BP | 1 |
| Davidson, CJ | 4 |
| Gorelick, PB | 1 |
| Jonas, S | 1 |
| Grieco, G | 1 |
| Manor, SM | 1 |
| Guillory, GS | 1 |
| Jain, SP | 1 |
| Andersohn, F | 1 |
| Hagmann, FG | 1 |
| Garbe, E | 1 |
| von Mach, MA | 1 |
| Eich, A | 1 |
| Weilemann, LS | 1 |
| Münzel, T | 1 |
| Yagi, H | 4 |
| Szułdrzyński, K | 1 |
| Dropiński, J | 1 |
| Szczeklik, W | 1 |
| Bennett, C | 1 |
| Oo, TH | 1 |
| Patel, TN | 1 |
| Kreindel, M | 1 |
| Lincoff, AM | 1 |
| Matsuda, N | 1 |
| Yoshihara, A | 1 |
| Nishikata, R | 1 |
| Matsuda, T | 1 |
| Endo, K | 1 |
| Yamamoto, T | 1 |
| Buffie, CG | 1 |
| Tevar, AD | 1 |
| De Masi, D | 1 |
| Davidson, C | 1 |
| Sadler, JE | 1 |
| Kato, S | 1 |
| Uemura, M | 1 |
| Copelovitch, L | 1 |
| Kaplan, BS | 1 |
| Takahashi, R | 1 |
| Fukusako, T | 1 |
| Yamashita, H | 1 |
| Omoto, M | 1 |
| Matsuda, K | 1 |
| Shinohara, K | 2 |
| Ishii, Y | 1 |
| Ebata, H | 1 |
| Satoh, K | 1 |
| Ueda, H | 1 |
| Harada, M | 1 |
| Mashiko, N | 1 |
| Nouno, R | 1 |
| Tanikawa, K | 1 |
| Hidaka, T | 1 |
| Kovacs, MJ | 1 |
| Soong, PY | 1 |
| Chin-Yee, IH | 1 |
| Franchimont, D | 1 |
| Frère, P | 1 |
| Lebrun, F | 1 |
| Fassotte, MF | 1 |
| D'Orio, V | 1 |
| Jimenez Moreno, FJ | 1 |
| Junquera Florez, F | 1 |
| Nuvias Casals, J | 1 |
| Castells Fuste, L | 1 |
| Gonzalez Fernandez, A | 1 |
| Kodama, K | 1 |
| Nomura, T | 1 |
| Yasui, K | 1 |
| Matsuo, T | 1 |
| Miyaoka, Y | 1 |
| Urano, Y | 1 |
| Nameda, Y | 1 |
| Shigekiyo, T | 1 |
| Horie, T | 1 |
| Sano, N | 1 |
| Arase, S | 1 |
| Ariyoshi, K | 1 |
| Ruirong, X | 1 |
| Kupfer, Y | 1 |
| Tessler, S | 1 |
| Sheffield, JV | 1 |
| Merrens, E | 1 |
| Weinberg, PD | 4 |
| Rozenberg-Ben-Dror, K | 1 |
| Green, D | 3 |
| Love, BB | 1 |
| Biller, J | 1 |
| Gent, M | 1 |
| Pinevich, AJ | 1 |
| Feldman, MD | 4 |
| Mukamal, KJ | 1 |
| Wu, B | 1 |
| McPhedran, P | 1 |
| Jamar, S | 1 |
| Vanderheyden, M | 1 |
| Janssens, L | 1 |
| Hermans, L | 1 |
| Jamar, R | 1 |
| Verstreken, G | 1 |
| Chen, DK | 1 |
| Kim, JS | 1 |
| Sutton, DM | 1 |
| Steinhubl, SR | 1 |
| Tan, WA | 1 |
| Foody, JM | 1 |
| Topol, EJ | 1 |
| Brown, DL | 1 |
| McCullough, PA | 2 |
| Marks, KR | 2 |
| Elangovan, L | 1 |
| Fabris, F | 1 |
| Luzzatto, G | 1 |
| Sartori, MT | 1 |
| Zanella, I | 1 |
| Girolami, A | 1 |
| Leavey, SF | 1 |
| Weinberg, J | 1 |
| Venegoni, M | 1 |
| Conforti, A | 1 |
| Cocci, A | 1 |
| Leone, R | 1 |
| Hernández, JA | 1 |
| Ribera, JM | 1 |
| Bosch, MA | 1 |
| Sancho, JM | 1 |
| Bennett, RH | 1 |
| Carlsson, J | 1 |
| Miketic, S | 1 |
| Bätge, R | 1 |
| Riedel, P | 1 |
| Rahlf, G | 1 |
| Tebbe, U | 1 |
| Baker, KR | 1 |
| Chemnitz, JM | 1 |
| Schulz, A | 1 |
| Salameh, A | 1 |
| Scheid, C | 1 |
| Müller, R | 1 |
| Draube, A | 1 |
| Diehl, V | 1 |
| Söhngen, D | 1 |
| SoRelle, R | 1 |
| Tsai, HM | 2 |
| Rice, L | 1 |
| Chow, TW | 1 |
| Connors, JM | 1 |
| Carwile, JM | 1 |
| Bell, WR | 1 |
| Tarantolo, SR | 1 |
| McCarthy, LJ | 1 |
| Hatfield, AJ | 1 |
| Wood, AJ | 1 |
| Sannes, MR | 1 |
| Modi, KS | 1 |
| Chinnakotla, S | 1 |
| Leone, JP | 1 |
| Fidler, ME | 1 |
| Hammeke, MD | 1 |
| Tarantolo, S | 1 |
| Sallière, D | 1 |
| Kassler-Taub, KB | 1 |
| Trontell, AE | 1 |
| Honig, PK | 1 |
| Brooker, JZ | 1 |
| Cheung, RT | 1 |
| Goldstein, MR | 1 |
| Hankey, GJ | 1 |
| Dunlop, H | 1 |
| Zauner, C | 1 |
| Funk, GC | 1 |
| Birnbacher, R | 1 |
| Kim, J | 1 |
| Costello, C | 1 |
| Nara, W | 1 |
| Ashley, I | 1 |
| Rosner, F | 1 |
| Reichenberger, F | 1 |
| Wirtz, H | 1 |
| Paschke, R | 1 |
| Sugio, Y | 1 |
| Okamura, T | 1 |
| Shimoda, K | 1 |
| Ishizashi, H | 2 |
| Niho, Y | 1 |
| Inaba, S | 1 |
| Orimo, S | 1 |
| Ozawa, E | 1 |
| Ellie, E | 1 |
| Durrieu, C | 1 |
| Besse, P | 1 |
| Julien, J | 1 |
| Gbipki-Benissan, G | 1 |
| Capra, R | 1 |
| Marcianò, N | 1 |
| Fieni, F | 1 |
| Capucci, M | 1 |
| Ferremi, P | 1 |
| Orlandini, A | 1 |
| Page, Y | 1 |
| Tardy, B | 2 |
| Zeni, F | 1 |
| Comtet, C | 1 |
| Terrana, R | 1 |
| Bertrand, JC | 2 |
| Vianelli, N | 1 |
| Bandini, G | 1 |
| Catani, L | 1 |
| Mattioli Belmonte, M | 1 |
| Gugliotta, L | 1 |
| del Zoppo, GJ | 1 |
| Billard, JL | 1 |
| Page, R | 1 |
| Vermesch-Vergnaud, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ADAMTS13-related Prognostic Factors in Adult and Pediatric Thrombotic Thrombocytopenic Purpura[NCT00426686] | 153 participants (Actual) | Observational | 2006-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
18 reviews available for ticlopidine and Purpura, Thrombotic Thrombocytopenic
| Article | Year |
|---|---|
Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008).
Topics: ADAM Proteins; ADAMTS13 Protein; Adverse Drug Reaction Reporting Systems; Animals; Autoantibodies; C | 2009 |
The safety of clopidogrel.
Topics: Acute Coronary Syndrome; Clopidogrel; Drug-Related Side Effects and Adverse Reactions; Hemorrhage; H | 2011 |
Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR).
Topics: Clopidogrel; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purpura, | 2012 |
Clopidogrel and thrombotic thrombocytopenic purpura: no clear case for causality.
Topics: Causality; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopeni | 2003 |
[Clinical features and laboratory findings of thrombotic thrombocytopenic purpura associated with ticlopidine].
Topics: ADAM Proteins; ADAMTS13 Protein; Autoantibodies; Biomarkers; Diagnosis, Differential; Humans; Metall | 2005 |
Drug-induced thrombotic microangiopathy.
Topics: ADAM Proteins; ADAMTS13 Protein; Antibiotics, Antineoplastic; Cyclosporine; Endothelium, Vascular; F | 2005 |
[Brain nerve symptoms due to thrombotic microangiopathy].
Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Aged; Aged, 80 and over; Cerebrovascular Disorders; Clopidog | 2007 |
The thrombotic microangiopathies.
Topics: Hematopoietic Stem Cell Transplantation; Hemolytic-Uremic Syndrome; HIV Infections; Humans; Lupus Er | 2008 |
[Drug-induced thrombotic thrombocytopenic purpura].
Topics: Antirheumatic Agents; Aspirin; Cyclosporine; Diagnosis, Differential; Humans; Immunosuppressive Agen | 2007 |
Adverse haematological effects of ticlopidine. Prevention, recognition and management.
Topics: Anemia, Aplastic; Cerebrovascular Disorders; Female; Humans; Male; Neutropenia; Platelet Aggregation | 1998 |
Thrombotic thrombocytopenic purpura associated with ticlopidine use: a report of 3 cases and review of the literature.
Topics: Aged; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thromb | 1999 |
Aspirin and ticlopidine after routine coronary stenting: the gold standard as of 1999.
Topics: Anemia, Aplastic; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Co | 1999 |
Thrombotic thrombocytopenic purpura associated with ticlopidine therapy.
Topics: Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inh | 1997 |
Thrombotic thrombocytopenic purpura associated with ticlopidine in the setting of coronary artery stents and stroke prevention.
Topics: Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; | 1999 |
Thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
Topics: Anti-Bacterial Agents; Child; Diagnosis, Differential; Erythropoietin; Hemolytic-Uremic Syndrome; Hu | 2000 |
Clopidogrel (Plavix): hematological reactions.
Topics: Aged; Aged, 80 and over; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibi | 2001 |
Thrombotic thrombocytopenic purpura associated with clopidogrel administration: case report and brief review.
Topics: Angioplasty, Balloon, Coronary; Clopidogrel; HIV Infections; Humans; Male; Middle Aged; Platelet Agg | 2001 |
Antiplatelet therapy in thrombotic thrombocytopenic purpura.
Topics: Aspirin; Blood Platelets; Dextrans; Dipyridamole; Epoprostenol; Humans; Microcirculation; Platelet A | 1987 |
2 trials available for ticlopidine and Purpura, Thrombotic Thrombocytopenic
| Article | Year |
|---|---|
Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy.
Topics: ADAMTS13 Protein; Adult; Autoantibodies; Autoimmune Diseases; Clopidogrel; Cohort Studies; Cross-Sec | 2016 |
Thrombotic thrombocytopenic purpura (TTP): initial treatment with plasma exchange plus steroids and immunosuppressive agents for relapsing cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic; Bilirubin; Biomarkers; Combined Modal | 2003 |
72 other studies available for ticlopidine and Purpura, Thrombotic Thrombocytopenic
| Article | Year |
|---|---|
Clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Renal In | 2023 |
Ticlopidine-associated ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in 22 persons in Japan: a report from the Southern Network on Adverse Reactions (SONAR).
Topics: ADAM Proteins; ADAMTS13 Protein; Enzyme Activation; Humans; Japan; Purpura, Thrombotic Thrombocytope | 2013 |
Aortic thrombosis secondary to clopidogrel-related thrombotic thrombocytopenic purpura.
Topics: Aged; Aorta, Abdominal; Aortic Diseases; Clopidogrel; Female; Humans; Platelet Aggregation Inhibitor | 2014 |
Congenital and acquired ADAMTS13 deficiency: Two mechanisms, one patient.
Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Autoantibodies; Environmental Exposure; Family Health; Femal | 2015 |
Clopidogrel-induced refractory thrombotic thrombocytopenic purpura successfully treated with rituximab.
Topics: ADAMTS13 Protein; Adult; Clopidogrel; Female; Humans; L-Lactate Dehydrogenase; Platelet Count; Purpu | 2016 |
[Is this case really the one of clopidogrel-associated thrombotic thrombocytopenic purpura?].
Topics: Clopidogrel; Humans; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 2008 |
[From gastroenteritis complicated by acute renal failure to... the Moschcowitz syndrome].
Topics: Acute Kidney Injury; Aged; Diagnosis, Differential; Gastroenteritis; Humans; Male; Plasmapheresis; P | 2009 |
[Clopidogrel-associated thrombotic thrombocytopenic purpura].
Topics: ADAM Proteins; ADAMTS13 Protein; Autoantibodies; Cerebral Infarction; Clopidogrel; Humans; Platelet | 2009 |
[Clopidogrel induced thrombotic thrombocytopenic purpura].
Topics: Clopidogrel; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Purp | 2011 |
[Clopidogrel-associated thrombotic thrombocytopenic purpura].
Topics: ADAM Proteins; Aged; Clopidogrel; Enzyme Activation; Humans; Male; Plasma Exchange; Platelet Aggrega | 2012 |
Thrombotic thrombocytopenic purpura associated with clopidogrel: further evaluation.
Topics: Bayes Theorem; Causality; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic | 2002 |
Abciximab-induced thrombocytopenia.
Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Clopidogrel; Diagnosis, Differential; Hemolytic-U | 2002 |
TTP/HUS occurring in a simultaneous pancreas/kidney transplant recipient after clopidogrel treatment: evidence of a nonimmunological etiology.
Topics: Calcineurin; Clopidogrel; Graft Rejection; Hemolytic-Uremic Syndrome; Humans; Kidney Transplantation | 2002 |
Thrombotic thrombocytopenic purpura associated with ticlopidine.
Topics: Cardiovascular Diseases; Female; Fibrinolytic Agents; Humans; Middle Aged; Plasmapheresis; Platelet | 2003 |
Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades.
Topics: Adult; Aged; Apoptosis; Cells, Cultured; Clopidogrel; Endothelium, Vascular; Epithelial Cells; Femal | 2004 |
Clopidogrel-associated TTP: an update of pharmacovigilance efforts conducted by independent researchers, pharmaceutical suppliers, and the Food and Drug Administration.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Causality; Clopidogrel; Fem | 2004 |
Editorial comment--an approach to the estimation of the risk of TTP during clopidogrel therapy.
Topics: Clopidogrel; Drug Utilization; Humans; Incidence; Platelet Aggregation Inhibitors; Product Surveilla | 2004 |
Clopidogrel-induced thrombotic thrombocytopenic purpura-hemolytic uremic syndrome after coronary artery stenting.
Topics: Clopidogrel; Coronary Disease; Hemolytic-Uremic Syndrome; Humans; Male; Middle Aged; Platelet Aggreg | 2004 |
Thrombotic thrombocytopenic purpura/haemolytic uraemic syndrome associated with clopidogrel: report of two new cases.
Topics: Adult; Aged; Angina Pectoris; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Hemolytic-Ure | 2004 |
Subacute coronary stent thrombosis in a patient developing clopidogrel associated thrombotic thrombocytopenic purpura.
Topics: Aged; Angina, Unstable; Blood Vessel Prosthesis; Clopidogrel; Coronary Restenosis; Coronary Stenosis | 2005 |
[Thrombotic thrombocytopenic purpura -- a rare complication associated with clopidogrel therapy. A case report].
Topics: Clopidogrel; Female; Hemolytic-Uremic Syndrome; Humans; Middle Aged; Platelet Aggregation Inhibitors | 2005 |
Clopidogrel-associated thrombotic thrombocytopenic purpura presenting with coronary artery thrombosis.
Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Thrombosis; Female; Humans; L-Lactate De | 2006 |
Use of ticlopidine and cilostazol after intracoronary drug-eluting stent placement in a patient with previous clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.
Topics: ADAM Proteins; ADAMTS1 Protein; Aged; Apoptosis; Aspirin; Autoantibodies; Cilostazol; Clopidogrel; C | 2006 |
[A case of ticlopidine-associated thrombotic thrombocytopenic purpura: special emphasis on diffusion weighted MRI].
Topics: ADAM Proteins; Aged; Brain; Diffusion Magnetic Resonance Imaging; Fibrinolytic Agents; Humans; Iofet | 2006 |
Two mechanistic pathways for thienopyridine-associated thrombotic thrombocytopenic purpura: a report from the SERF-TTP Research Group and the RADAR Project.
Topics: Adverse Drug Reaction Reporting Systems; Age Distribution; Aged; Analysis of Variance; Clopidogrel; | 2007 |
[Case of thrombotic thrombocytopenic purpura associated with clopidogrel].
Topics: Aged, 80 and over; Cerebral Infarction; Clopidogrel; Fatal Outcome; Female; Humans; Plasma Exchange; | 2007 |
[Case of thrombotic thrombocytopenic purpura. Successful treatment with ticlopidine].
Topics: Adult; Anticoagulants; Female; Humans; Purpura, Thrombotic Thrombocytopenic; Thiophenes; Ticlopidine | 1984 |
Thrombotic thrombocytopenic purpura associated with ticlopidine.
Topics: Aged; Humans; Ischemic Attack, Transient; Male; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 1993 |
[Clinical case of the month. Moskowitz syndrome in a patient treated with ticlopidine].
Topics: Female; Fibrinolytic Agents; Humans; Hypertension; Middle Aged; Purpura, Thrombotic Thrombocytopenic | 1996 |
[Thrombotic thrombocytopenic purpura associated with ticlopidine].
Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Ischemic Attack, Transient; Platelet Aggregation In | 1996 |
[Thrombotic thrombocytopenic purpura after administration of ticlopidine].
Topics: Humans; Male; Middle Aged; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thro | 1996 |
A case of dermatomyositis complicated by thrombotic thrombocytopenic purpura.
Topics: Anti-Inflammatory Agents; Dermatomyositis; Dipyridamole; Dyspnea; Epoprostenol; Fatal Outcome; Fever | 1997 |
Thrombotic thrombocytopenic purpura caused by ticlopidine, successfully treated by plasmapheresis.
Topics: Aged; Female; Humans; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocy | 1997 |
Ticlopidine and thrombotic thrombocytopenic purpura.
Topics: Adult; Angioplasty, Balloon, Coronary; Female; Humans; Middle Aged; Platelet Aggregation Inhibitors; | 1997 |
More about thrombotic thrombocytopenic purpura.
Topics: Humans; Platelet Transfusion; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 1998 |
Thrombotic thrombocytopenic purpura associated with ticlopidine. A review of 60 cases.
Topics: Adult; Aged; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Plasmapheresis; Platelet | 1998 |
Thrombotic thrombocytopenic purpura after stenting and ticlopidine.
Topics: Coronary Disease; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ret | 1998 |
Ticlopidine-associated thrombotic thrombocytopenic purpura.
Topics: Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 1998 |
Thrombotic thrombocytopenic purpura: a rare but potential life-threatening complication following ticlopidine administration.
Topics: Aged; Coronary Disease; Humans; Male; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Thro | 1998 |
Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting. EPISTENT Investigators. Evaluation of Platelet IIb/IIIa Inhibitor for Stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggrega | 1999 |
Absence of thrombotic thrombocytopenic purpura following coronary stenting in the ticlopidine era.
Topics: Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Retrospective Studies | 1999 |
Thrombotic thrombocytopenic purpura associated with ticlopidine use.
Topics: Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; | 1999 |
A paradoxical side-effect of antiaggregating treatment with ticlopidine: the Moschowitz syndrome.
Topics: Fibrinolytic Agents; Humans; Male; Middle Aged; Purpura, Thrombotic Thrombocytopenic; Thrombosis; Ti | 1999 |
Spontaneous reports of ticlopidine-associated thrombotic thrombocytopenic purpura from 2 Italian regions.
Topics: Fibrinolytic Agents; Humans; Italy; Platelet Aggregation Inhibitors; Product Surveillance, Postmarke | 1999 |
[Thrombotic thrombocytopenic purpura associated to ticlopidine].
Topics: Aged; Aged, 80 and over; Humans; Male; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thromboc | 1999 |
Ticlopidine and TTP after coronary stenting.
Topics: Angioplasty, Balloon; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Postoperative Compl | 1999 |
Ticlopidine and TTP after coronary stenting.
Topics: Angioplasty, Balloon; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Postoperative Compl | 1999 |
[Ticlopidine-associated thrombotic thrombocytopenic purpura (Morbus Moschcowitz)].
Topics: Aged; Brain Ischemia; Cerebral Infarction; Diagnosis, Differential; Fatal Outcome; Female; Humans; P | 2000 |
[Thrombotic thrombocytopenic purpura (Moschkowitz-syndrome) caused by ticlopidine].
Topics: Female; Humans; Middle Aged; Plasma; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Throm | 2000 |
Clopidogrel-associated thrombotic thrombocytopenic purpura identified.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ticlopid | 2000 |
Antibody inhibitors to von Willebrand factor metalloproteinase and increased binding of von Willebrand factor to platelets in ticlopidine-associated thrombotic thrombocytopenic purpura.
Topics: Aged; Aged, 80 and over; Autoantibodies; Blood Platelets; Case-Control Studies; Female; Humans; Immu | 2000 |
Thrombotic thrombocytopenic purpura associated with clopidogrel.
Topics: Adult; Aged; Clopidogrel; Fatal Outcome; Female; Humans; Male; Middle Aged; Plasma Exchange; Platele | 2000 |
Thrombotic thrombocytopenic purpura and clopidogrel--a need for new approaches to drug safety.
Topics: Adverse Drug Reaction Reporting Systems; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Produ | 2000 |
Acute renal failure and thrombocytopenia after ticlopidine--not necessarily thrombotic thrombocytopenic purpura.
Topics: Acute Kidney Injury; Aged; Coronary Disease; Diagnosis, Differential; Embolism, Cholesterol; Female; | 2000 |
Clopidogrel-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in a kidney/pancreas transplant recipient.
Topics: Adult; Clopidogrel; Coronary Disease; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathie | 2000 |
Clopidogrel and thrombotic thrombocytopenic purpura.
Topics: Clopidogrel; Drug Labeling; Humans; Platelet Aggregation Inhibitors; Product Surveillance, Postmarke | 2000 |
Clopidogrel and thrombotic thrombocytopenic purpura.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Product Surveillance, Postmarketing; Purpura, | 2000 |
Clopidogrel and thrombotic thrombocytopenic purpura.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ticlopid | 2000 |
Clopidogrel and thrombotic thrombocytopenic purpura.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Platelet Count; Purpura, Thrombotic Thrombocyt | 2000 |
Clopidogrel and thrombotic thrombocytopenic purpura.
Topics: Advertising; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Product Surveillance, Postmarketi | 2000 |
Clopidogrel and thrombotic thrombocytopenic purpura.
Topics: Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ticlopid | 2000 |
Platelet aggregation inhibition with ticlopidine in the treatment of stroke.
Topics: Acute Disease; Critical Care; Drug Eruptions; Drug Monitoring; Gastrointestinal Diseases; Humans; Ki | 2001 |
Role of transforming growth factor beta1 in microvascular endothelial cell apoptosis associated with thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome.
Topics: Apoptosis; Cell Cycle; Cell Lineage; Cells, Cultured; Coronary Vessels; Culture Media, Serum-Free; E | 2001 |
Clopidogrel and side effects.
Topics: Aged; Aged, 80 and over; Clopidogrel; Female; Humans; Platelet Aggregation Inhibitors; Purpura, Thro | 2001 |
Ticlopidine-Associated thrombotic thrombocytopenic purpura with an IgG-type inhibitor to von Willebrand factor-cleaving protease activity.
Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Arterial Occlusive Diseases; Autoantibodies; Humans; Immunog | 2001 |
Ticlopidine-induced thrombotic thrombocytopenic purpura: two case reports treated with plasma exchange plus steroids.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Dexamethasone; Fatal Outcome; Female; Humans; Pla | 2001 |
Simple plasma exchange reduced autoantibody to von Willebrand factor-cleaving protease in a Japanese man with ticlopidine-associated thrombotic thrombocytopenic purpura.
Topics: ADAM Proteins; ADAMTS13 Protein; Aged; Autoantibodies; Fibrinolytic Agents; Humans; Male; Metalloend | 2002 |
Thrombotic thrombocytopenic purpura associated with ticlopidine.
Topics: Aged; Humans; Male; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 1992 |
Cerebral hemorrhage and thrombotic thrombocytopenic purpura during ticlopidine treatment: case report.
Topics: Adult; Cerebral Hemorrhage; Combined Modality Therapy; Female; Humans; Plasma Exchange; Puerperal Di | 1992 |
Thrombotic thrombocytopenic purpura related to ticlopidine.
Topics: Aged; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Ne | 1991 |
Thrombotic thrombocytopenic purpura and ticlopidine.
Topics: Adult; Age Factors; Aged; Humans; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 1991 |
[Thrombocytopenic thrombotic purpura occurring in spite of antiaggregant treatment using ticlopidine].
Topics: Aged; Humans; L-Lactate Dehydrogenase; Male; Platelet Count; Purpura, Thrombotic Thrombocytopenic; T | 1989 |