Page last updated: 2024-11-05

ticlopidine and Pneumonia

ticlopidine has been researched along with Pneumonia in 15 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
" This study sought to characterize effects of clopidogrel on the incidence and severity of community-acquired pneumonia (CAP)."8.89Clopidogrel treatment and the incidence and severity of community acquired pneumonia in a cohort study and meta-analysis of antiplatelet therapy in pneumonia and critical illness. ( Abdel-Latif, A; Charnigo, R; Dunn, SP; Feola, DJ; Gross, AK; Li, Z; Martin, CA; Smyth, SS, 2013)
"A 65-year-old man, who had been given a diagnosis of angina pectoris, developed pneumonia 6 months after the initiation of clopidogrel to inhibit platelet aggregation."7.76[A case of drug-induced pneumonia caused by clopidogrel]. ( Hirata, K; Matsushita, H; Suzumura, T; Tamagaki, G; Watanabe, T; Yamada, S, 2010)
"Transient pancytopenia as an adverse hematologic reaction due to ticlopidine."7.73[Transient pancytopenia due to ticlopidine--a case report]. ( Barg, W; Biełous-Wilk, A; Chmielowicz, B; Grabowski, M; Kopec, A; Panaszek, B, 2005)
"To report a case of ticlopidine-induced neutropenia occurring 18 days after discontinuation of the drug."7.69Delayed neutropenia with ticlopidine. ( Farver, DK; Hansen, LA, 1994)
" We analysed adverse events (AEs) consistent with either pulmonary infection or sepsis, and subsequent mortality, in 18,421 PLATO patients treated with ticagrelor or clopidogrel."6.79Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study. ( Åsenblad, N; Becker, RC; Cannon, CP; Held, C; Husted, SE; James, SK; Siegbahn, A; Steg, PG; Storey, RF; Varenhorst, C; Wallentin, L; Ycas, J, 2014)
"Ticlopidine is an antiplatelet agent that has been proven efficacious in preventing vascular events in patients with a history of vasculopathy."5.30Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative. ( Armstrong, PW; Brown, NE; Gill, S; Majumdar, S, 1997)
" This study sought to characterize effects of clopidogrel on the incidence and severity of community-acquired pneumonia (CAP)."4.89Clopidogrel treatment and the incidence and severity of community acquired pneumonia in a cohort study and meta-analysis of antiplatelet therapy in pneumonia and critical illness. ( Abdel-Latif, A; Charnigo, R; Dunn, SP; Feola, DJ; Gross, AK; Li, Z; Martin, CA; Smyth, SS, 2013)
"Using a mouse model of intra-abdominal sepsis and acute lung injury, we investigated the role of the P2Y12 receptor in neutrophil migration and lung inflammation in P2Y12 null mice and in mice pretreated with the P2Y12 antagonist clopidogrel."3.83P2Y12 Receptor Modulates Sepsis-Induced Inflammation. ( Kilpatrick, LE; Kunapuli, SP; Liverani, E; Rico, MC; Tsygankov, AY, 2016)
"A 65-year-old man, who had been given a diagnosis of angina pectoris, developed pneumonia 6 months after the initiation of clopidogrel to inhibit platelet aggregation."3.76[A case of drug-induced pneumonia caused by clopidogrel]. ( Hirata, K; Matsushita, H; Suzumura, T; Tamagaki, G; Watanabe, T; Yamada, S, 2010)
"Transient pancytopenia as an adverse hematologic reaction due to ticlopidine."3.73[Transient pancytopenia due to ticlopidine--a case report]. ( Barg, W; Biełous-Wilk, A; Chmielowicz, B; Grabowski, M; Kopec, A; Panaszek, B, 2005)
"To report a case of ticlopidine-induced neutropenia occurring 18 days after discontinuation of the drug."3.69Delayed neutropenia with ticlopidine. ( Farver, DK; Hansen, LA, 1994)
" We analysed adverse events (AEs) consistent with either pulmonary infection or sepsis, and subsequent mortality, in 18,421 PLATO patients treated with ticagrelor or clopidogrel."2.79Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study. ( Åsenblad, N; Becker, RC; Cannon, CP; Held, C; Husted, SE; James, SK; Siegbahn, A; Steg, PG; Storey, RF; Varenhorst, C; Wallentin, L; Ycas, J, 2014)
" Proton pump inhibitors cause few adverse effects with short-term use; however, long-term use has been scrutinized for appropriateness, drug-drug interactions, and the potential for adverse effects (e."2.48Reducing adverse effects of proton pump inhibitors. ( Ament, PW; Dicola, DB; James, ME, 2012)
"Gastroesophageal reflux disease (GERD) affects 10% to 20% of the western world's population."1.42What are the precautions with proton pump inhibitor use for reflux disease? ( Mospan, CM, 2015)
"Ticlopidine is an antiplatelet agent that has been proven efficacious in preventing vascular events in patients with a history of vasculopathy."1.30Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative. ( Armstrong, PW; Brown, NE; Gill, S; Majumdar, S, 1997)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's2 (13.33)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Storey, RF1
James, SK1
Siegbahn, A1
Varenhorst, C1
Held, C1
Ycas, J1
Husted, SE1
Cannon, CP1
Becker, RC1
Steg, PG1
Åsenblad, N1
Wallentin, L1
Mospan, CM1
Otoshi, T1
Kataoka, Y1
Nakagawa, A1
Otsuka, K1
Tomii, K1
Liverani, E1
Rico, MC1
Tsygankov, AY1
Kilpatrick, LE1
Kunapuli, SP1
Eusebi, LH1
Rabitti, S1
Artesiani, ML1
Gelli, D1
Montagnani, M1
Zagari, RM1
Bazzoli, F1
Winning, J1
Reichel, J1
Eisenhut, Y1
Hamacher, J1
Kohl, M1
Deigner, HP1
Claus, RA1
Bauer, M1
Lösche, W1
Tamagaki, G1
Matsushita, H1
Suzumura, T1
Watanabe, T1
Yamada, S1
Hirata, K1
Madanick, RD1
Ament, PW1
Dicola, DB1
James, ME1
Gross, AK1
Dunn, SP1
Feola, DJ1
Martin, CA1
Charnigo, R1
Li, Z1
Abdel-Latif, A1
Smyth, SS1
Grabowski, M1
Barg, W1
Biełous-Wilk, A1
Kopec, A1
Chmielowicz, B1
Panaszek, B1
Farver, DK1
Hansen, LA1
Gill, S1
Majumdar, S1
Brown, NE1
Armstrong, PW1
Watanabe, M1
Machida, K1
Higashimoto, I1
Niina, K1
Kawabata, M1
Osame, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Institute of Emergency and Critical Care Medicine , School of Yang-Ming University[NCT01588886]9,000 participants (Actual)Observational2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for ticlopidine and Pneumonia

ArticleYear
Proton pump inhibitors: Risks of long-term use.
    Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:7

    Topics: Calcium; Cardiovascular Diseases; Clopidogrel; Dementia; Drug Interactions; Fractures, Bone; Gastroi

2017
Proton pump inhibitor side effects and drug interactions: much ado about nothing?
    Cleveland Clinic journal of medicine, 2011, Volume: 78, Issue:1

    Topics: Anemia, Iron-Deficiency; Anti-Ulcer Agents; Clopidogrel; Drug Interactions; Fractures, Spontaneous;

2011
Reducing adverse effects of proton pump inhibitors.
    American family physician, 2012, Jul-01, Volume: 86, Issue:1

    Topics: Anemia, Iron-Deficiency; Clopidogrel; Clostridioides difficile; Critical Care; Diarrhea; Drug Intera

2012
Clopidogrel treatment and the incidence and severity of community acquired pneumonia in a cohort study and meta-analysis of antiplatelet therapy in pneumonia and critical illness.
    Journal of thrombosis and thrombolysis, 2013, Volume: 35, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Clopidogrel; Cohort Studies; Community-Acquired Infections; Critical

2013
[Multiple pulmonary nodules due to ticlopidine-induced pneumonitis].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 1999, Volume: 37, Issue:10

    Topics: Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Pneumonia; Radiography, Thoracic; Solita

1999

Trials

1 trial available for ticlopidine and Pneumonia

ArticleYear
Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study.
    Platelets, 2014, Volume: 25, Issue:7

    Topics: Adenosine; Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet A

2014

Other Studies

9 other studies available for ticlopidine and Pneumonia

ArticleYear
What are the precautions with proton pump inhibitor use for reflux disease?
    JAAPA : official journal of the American Academy of Physician Assistants, 2015, Volume: 28, Issue:12

    Topics: Anemia, Iron-Deficiency; Clopidogrel; Community-Acquired Infections; Deficiency Diseases; Drug Inter

2015
Clinical Features and Outcomes of Diffuse Alveolar Hemorrhage During Antithrombotic Therapy: A Retrospective Cohort Study.
    Lung, 2016, Volume: 194, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Connective Tissue Diseases; Female

2016
P2Y12 Receptor Modulates Sepsis-Induced Inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:5

    Topics: Acute Lung Injury; Animals; Blood Platelets; Clopidogrel; Cytokines; Genetic Predisposition to Disea

2016
Anti-platelet drugs and outcome in severe infection: clinical impact and underlying mechanisms.
    Platelets, 2009, Volume: 20, Issue:1

    Topics: Adult; Aged; Animals; Cell Line; Clopidogrel; Female; Fibrin; Gene Expression Profiling; Hemodynamic

2009
[A case of drug-induced pneumonia caused by clopidogrel].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2010, Volume: 48, Issue:5

    Topics: Aged; Angina Pectoris; Clopidogrel; Humans; Male; Platelet Aggregation Inhibitors; Pneumonia; Ticlop

2010
Side effects of proton pump inhibitors.
    American family physician, 2012, Jul-01, Volume: 86, Issue:1

    Topics: Clopidogrel; Diarrhea; Drug Interactions; Gastroesophageal Reflux; Hip Fractures; Humans; Platelet A

2012
[Transient pancytopenia due to ticlopidine--a case report].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Female; Fibrinolytic Agents; Heart Failure; Humans; Pancytopenia; Pneum

2005
Delayed neutropenia with ticlopidine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12

    Topics: Aged; Blood Cell Count; Female; Humans; Ischemic Attack, Transient; Neutropenia; Pneumonia; Ticlopid

1994
Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Drug Resistance; Fatal Outcome; Female; Humans; Middle Aged; Neutr

1997