ticlopidine has been researched along with Pancreatic Neoplasms in 2 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "ESSENTIALS: Cancer patients have a high rate of venous thrombosis (VT) but the underlying mechanisms are unknown." | 1.43 | Tissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice. ( Bergmeier, W; Boulaftali, Y; Cooley, BC; Dee, R; Fuentes, R; Geddings, JE; Getz, TM; Hisada, Y; Key, NS; Mackman, N; Whelihan, M; Wolberg, AS, 2016) |
| "We observed that pancreatic cancer cell derived microparticles expressed TF, its inhibitor tissue factor pathway inhibitor (TFPI) as well as the integrins αvβ1 and αvβ3." | 1.42 | Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo. ( Darbousset, R; Dignat-George, F; Dubois, C; Mezouar, S; Panicot-Dubois, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mezouar, S | 1 |
| Darbousset, R | 1 |
| Dignat-George, F | 1 |
| Panicot-Dubois, L | 1 |
| Dubois, C | 1 |
| Geddings, JE | 1 |
| Hisada, Y | 1 |
| Boulaftali, Y | 1 |
| Getz, TM | 1 |
| Whelihan, M | 1 |
| Fuentes, R | 1 |
| Dee, R | 1 |
| Cooley, BC | 1 |
| Key, NS | 1 |
| Wolberg, AS | 1 |
| Bergmeier, W | 1 |
| Mackman, N | 1 |
2 other studies available for ticlopidine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo.
Topics: Animals; Blood Coagulation; Blotting, Western; Cell-Derived Microparticles; Clopidogrel; Disease Mod | 2015 |
Tissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice.
Topics: Adenocarcinoma; Animals; Blood Platelets; Cell Line, Tumor; Cell-Derived Microparticles; Clopidogrel | 2016 |