ticlopidine has been researched along with Metastase in 7 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To test whether disruption of platelet function with clopidogrel and aspirin would decrease the number of circulating tumor cells (CTCs) in patients with metastatic breast cancer, a randomized phase II study was performed." | 5.17 | A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancer. ( Eby, CS; Johnson, F; Lammers, PE; Naughton, MJ; Pluard, TJ; Roop, RP; Schneider, JG; Van Poznak, C; Weilbaecher, KN, 2013) |
| "In lay terms "cancers follow bleeding", which seems to be true for antithrombotic agents in general." | 2.52 | Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges. ( Cabrera-Fuentes, HA; Cherepanov, V; Kim, MH; Serebruany, VL, 2015) |
| "We observed that pancreatic cancer cell derived microparticles expressed TF, its inhibitor tissue factor pathway inhibitor (TFPI) as well as the integrins αvβ1 and αvβ3." | 1.42 | Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo. ( Darbousset, R; Dignat-George, F; Dubois, C; Mezouar, S; Panicot-Dubois, L, 2015) |
| "Aspirin use was also associated with reduced rates of distant metastases at 5 years (12." | 1.40 | Aspirin improves outcome in high risk prostate cancer patients treated with radiation therapy. ( Choe, KS; Chun, SG; Hannan, R; Jacobs, CD; Kim, DW; Lotan, Y; Pistenmaa, DA; Roehrborn, CG; Xie, XJ; Yan, J, 2014) |
| "However, the number and size of lung metastases were reduced in treated animals when examined at the time of sacrifice." | 1.31 | Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model. ( Bergerat, JP; Cazenave, JP; Céraline, J; Chenard, MP; Deplanque, G; Klein-Soyer, C; Mah-Becherel, MC, 2002) |
| "Pulmonary metastases with CT26 cells could be inhibited by induction of thrombocytopenia, and reconstituted by infusion of either murine or human platelets." | 1.27 | Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. ( Ambrogio, C; Coller, BS; Karpatkin, S; Pearlstein, E, 1988) |
| "Ticlopidine was administered orally at the selected dose (200 mg/kg/day), to the rodents using different dose schedules and the inhibitory effects on spontaneous lung metastases of the Lewis lung carcinoma were studied." | 1.27 | Effects of ticlopidine on metastasis production in mice bearing Lewis lung carcinoma. ( Carretero, F; de Castellarnau, C; Fabra, A; Martínez, E; Rutllant, ML; Sancho, MJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roop, RP | 1 |
| Naughton, MJ | 1 |
| Van Poznak, C | 1 |
| Schneider, JG | 1 |
| Lammers, PE | 1 |
| Pluard, TJ | 1 |
| Johnson, F | 1 |
| Eby, CS | 1 |
| Weilbaecher, KN | 1 |
| Jacobs, CD | 1 |
| Chun, SG | 1 |
| Yan, J | 1 |
| Xie, XJ | 1 |
| Pistenmaa, DA | 1 |
| Hannan, R | 1 |
| Lotan, Y | 1 |
| Roehrborn, CG | 1 |
| Choe, KS | 1 |
| Kim, DW | 1 |
| Mezouar, S | 1 |
| Darbousset, R | 1 |
| Dignat-George, F | 1 |
| Panicot-Dubois, L | 1 |
| Dubois, C | 1 |
| Serebruany, VL | 1 |
| Cherepanov, V | 1 |
| Cabrera-Fuentes, HA | 1 |
| Kim, MH | 1 |
| Mah-Becherel, MC | 1 |
| Céraline, J | 1 |
| Deplanque, G | 1 |
| Chenard, MP | 1 |
| Bergerat, JP | 1 |
| Cazenave, JP | 1 |
| Klein-Soyer, C | 1 |
| Karpatkin, S | 1 |
| Pearlstein, E | 1 |
| Ambrogio, C | 1 |
| Coller, BS | 1 |
| Fabra, A | 1 |
| de Castellarnau, C | 1 |
| Carretero, F | 1 |
| Martínez, E | 1 |
| Sancho, MJ | 1 |
| Rutllant, ML | 1 |
1 review available for ticlopidine and Metastase
| Article | Year |
|---|---|
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
Topics: Adenosine; Animals; Anticarcinogenic Agents; Aspirin; Blood Platelets; Carcinogenicity Tests; Clopid | 2015 |
1 trial available for ticlopidine and Metastase
| Article | Year |
|---|---|
A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancer.
Topics: Aspirin; Blood Platelets; Breast Neoplasms; Case-Control Studies; Clopidogrel; Drug Therapy, Combina | 2013 |
5 other studies available for ticlopidine and Metastase
| Article | Year |
|---|---|
Aspirin improves outcome in high risk prostate cancer patients treated with radiation therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chemoradiotherapy; Clopidogrel; Drug Screening Ass | 2014 |
Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo.
Topics: Animals; Blood Coagulation; Blotting, Western; Cell-Derived Microparticles; Clopidogrel; Disease Mod | 2015 |
Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Cell Division; Clopidogrel; Disease Models, Animal; Foot; G | 2002 |
Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Humans; Immunologic Techniques; Lung Neop | 1988 |
Effects of ticlopidine on metastasis production in mice bearing Lewis lung carcinoma.
Topics: Animals; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Platelet Aggregation; Ticlop | 1987 |