ticlopidine has been researched along with Melanoma in 4 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A new platelet aggregation inhibitor compound, 5-(2-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-C]pyridine hydrochloride (ticlopidine), was examined for its inhibitory effects on blood-borne metastasis using three different rodent tumors (B16 melanoma, Lewis lung carcinoma, and rat ascites hepatoma, AH130)." | 3.66 | Effects of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (Ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis. ( Ishihara, M; Kinjo, M; Kohga, S; Ogawa, H; Tanaka, K; Tanaka, N, 1981) |
| "However, the number and size of lung metastases were reduced in treated animals when examined at the time of sacrifice." | 1.31 | Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model. ( Bergerat, JP; Cazenave, JP; Céraline, J; Chenard, MP; Deplanque, G; Klein-Soyer, C; Mah-Becherel, MC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Provost, P | 1 |
| Blocklet, D | 1 |
| Renard, M | 1 |
| Stoupel, E | 1 |
| Thoma, P | 1 |
| Vereecken, P | 1 |
| Bando, H | 1 |
| Yamashita, T | 1 |
| Tsubura, E | 1 |
| Kohga, S | 1 |
| Kinjo, M | 1 |
| Tanaka, K | 1 |
| Ogawa, H | 1 |
| Ishihara, M | 1 |
| Tanaka, N | 1 |
| Mah-Becherel, MC | 1 |
| Céraline, J | 1 |
| Deplanque, G | 1 |
| Chenard, MP | 1 |
| Bergerat, JP | 1 |
| Cazenave, JP | 1 |
| Klein-Soyer, C | 1 |
4 other studies available for ticlopidine and Melanoma
| Article | Year |
|---|---|
Cardiac masses in a patient with AJCC stage II melanoma: cautious interpretation of the magnetic resonance imaging.
Topics: Aged; Clopidogrel; Hematoma; Humans; Magnetic Resonance Imaging; Male; Mediastinal Diseases; Mediast | 2009 |
Effects of antiplatelet agents on pulmonary metastases.
Topics: Adenosine Diphosphate; Animals; Depression, Chemical; Diltiazem; Dipyridamole; Dose-Response Relatio | 1984 |
Effects of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (Ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis.
Topics: Animals; Cell Line; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Mic | 1981 |
Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Cell Division; Clopidogrel; Disease Models, Animal; Foot; G | 2002 |