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ticlopidine and Libman-Sacks Disease

ticlopidine has been researched along with Libman-Sacks Disease in 10 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"We examined the antithrombotic effect of ticlopidine on occlusive thrombi of small coronary arteries in (NZWxBXSB)F1 [(WxB)F1] male mice with myocardial infarction (MI) and systemic lupus erythematosus (SLE)."7.69Antithrombotic effect of ticlopidine on occlusive thrombi of small coronary arteries in (NZWxBXSB)F1 male mice with myocardial infarction and systemic lupus erythematosus. ( Fujiwara, H; Nakamura, Y; Shibata, Y; Suzuka, H; Tanaka, M; Yoshifusa, H, 1995)
"We examined the antithrombotic effect of ticlopidine on occlusive thrombi of small coronary arteries in (NZWxBXSB)F1 [(WxB)F1] male mice with myocardial infarction (MI) and systemic lupus erythematosus (SLE)."3.69Antithrombotic effect of ticlopidine on occlusive thrombi of small coronary arteries in (NZWxBXSB)F1 male mice with myocardial infarction and systemic lupus erythematosus. ( Fujiwara, H; Nakamura, Y; Shibata, Y; Suzuka, H; Tanaka, M; Yoshifusa, H, 1995)
"Hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP), and several other conditions are associated with TMA."2.44The thrombotic microangiopathies. ( Copelovitch, L; Kaplan, BS, 2008)
"Systemic lupus erythematosus is a chronic inflammatory disorder that predisposes to acute coronary thrombosis."1.37Effective management of acute coronary thrombosis in a young woman with lupus using aggressive medical therapy. ( Matthai, WH; Patel, PJ; Untereker, WJ, 2011)
"Ticlopidine hydrochloride is a platelet aggregation inhibitor that has been associated with thrombotic thrombocytopenic purpura, which is believed to be immune mediated."1.31Ticlopidine-induced lupus: a report of 4 cases. ( Berman, RS; Spiera, H; Spiera, RF; Werner, AJ, 2002)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yokoyama, T1
Usui, T1
Kiyama, K1
Nakashima, R1
Yukawa, N1
Kawabata, D1
Nojima, T1
Ohmura, K1
Fujii, T1
Mimori, T1
Duffau, P1
Seneschal, J1
Nicco, C1
Richez, C1
Lazaro, E1
Douchet, I1
Bordes, C1
Viallard, JF1
Goulvestre, C1
Pellegrin, JL1
Weil, B1
Moreau, JF1
Batteux, F1
Blanco, P1
Patel, PJ1
Matthai, WH1
Untereker, WJ1
Spiera, RF1
Berman, RS1
Werner, AJ1
Spiera, H1
Yang, CW1
Chen, YC1
Dunn, P1
Chang, MY1
Fang, JT1
Huang, CC1
Wang, L1
Erling, P1
Bengtsson, AA1
Truedsson, L1
Sturfelt, G1
Erlinge, D1
Ohtake, T1
Kobayashi, S1
Okamoto, K1
Oka, M1
Maesato, K1
Yasu, T1
Moriya, H1
Olivier, AC1
Hollman, JL1
Copelovitch, L1
Kaplan, BS1
Suzuka, H1
Fujiwara, H1
Tanaka, M1
Yoshifusa, H1
Nakamura, Y1
Shibata, Y1

Reviews

2 reviews available for ticlopidine and Libman-Sacks Disease

ArticleYear
Two cases of late-onset drug-induced lupus erythematosus caused by ticlopidine in elderly men.
    Modern rheumatology, 2010, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Autoantibodies; Histones; Humans; Lupus Erythematosus, Systemic; Mal

2010
The thrombotic microangiopathies.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:10

    Topics: Hematopoietic Stem Cell Transplantation; Hemolytic-Uremic Syndrome; HIV Infections; Humans; Lupus Er

2008

Trials

1 trial available for ticlopidine and Libman-Sacks Disease

ArticleYear
Thrombotic thrombocytopenic purpura (TTP): initial treatment with plasma exchange plus steroids and immunosuppressive agents for relapsing cases.
    Renal failure, 2003, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic; Bilirubin; Biomarkers; Combined Modal

2003

Other Studies

7 other studies available for ticlopidine and Libman-Sacks Disease

ArticleYear
Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus.
    Science translational medicine, 2010, Sep-01, Volume: 2, Issue:47

    Topics: Animals; Autoantibodies; Blood Platelets; CD40 Ligand; Clopidogrel; Dendritic Cells; Disease Models,

2010
Effective management of acute coronary thrombosis in a young woman with lupus using aggressive medical therapy.
    Cardiology, 2011, Volume: 118, Issue:1

    Topics: Adult; Aspirin; Clopidogrel; Coronary Thrombosis; Eptifibatide; Female; Fibrinolytic Agents; Heparin

2011
Ticlopidine-induced lupus: a report of 4 cases.
    Archives of internal medicine, 2002, Oct-28, Volume: 162, Issue:19

    Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Platelet Aggregation Inhibit

2002
Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosus.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:8

    Topics: Adolescent; Adult; Blood Platelets; Blotting, Western; Clopidogrel; Clusterin; Dimerization; Down-Re

2004
Ticlopidine-induced lupus with renal involvement.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:7

    Topics: Aged; Fibrinolytic Agents; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Lupus Erythematosus,

2006
Late in-stent thrombosis in a patient with systemic lupus erythematosus and hyperhomocysteinemia while on clopidogrel and aspirin.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Coagulation Disorders; Clopidogrel; Coronary Artery D

2006
Antithrombotic effect of ticlopidine on occlusive thrombi of small coronary arteries in (NZWxBXSB)F1 male mice with myocardial infarction and systemic lupus erythematosus.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:1

    Topics: Analysis of Variance; Animals; Antigen-Antibody Complex; Blood Urea Nitrogen; Coronary Disease; Coro

1995