Page last updated: 2024-11-05

ticlopidine and Kidney Diseases

ticlopidine has been researched along with Kidney Diseases in 29 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"In acute coronary syndrome patients with chronic kidney disease, ticagrelor compared with clopidogrel significantly reduces ischemic end points and mortality without a significant increase in major bleeding but with numerically more non-procedure-related bleeding."9.14Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial. ( Aylward, P; Buck, KK; Budaj, A; Cannon, CP; Cornel, JH; Harrington, RA; Horrow, J; James, S; Katus, H; Keltai, M; Lewis, BS; Parikh, K; Storey, RF; Szummer, K; Wallentin, L; Wojdyla, D, 2010)
"Although aspirin-clopidogrel combination is more useful for acute coronary syndrome (ACS), the renal safety of this combination had not been established."7.83Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome. ( Baber, M; HamidAkash, MS; Hussain, SB; Irfan, M; Qadir, MI; Rehman, A, 2016)
"Our aim was to identify risk factors for acute gastrointestinal (GI) bleeding in patients with myocardial infarction (MI) who were prescribed clopidogrel following hospital discharge."7.80Risk factors for acute gastrointestinal bleeding following myocardial infarction in veteran patients who are prescribed clopidogrel. ( Cuschieri, JR; Drawz, P; Falck-Ytter, Y; Wong, RC, 2014)
" We report a case of a large renal hematoma following SWL that resulted in nephrectomy in a type 2 diabetic patient with primary hyperparathyroidism using clopidogrel due to coronary heart disease CHD."7.73Serious clopidogrel associated renal hematoma in a type 2 diabetic patient with primary hyperparathyroidism after extracorporeal shock wave lithotripsy. ( Agil, C; Akay, F; Akay, H; Bahceci, M; Tuzcu, A, 2005)
"Ticagrelor is a new antiplatelet agent that was pitted against clopidogrel in the Platelet Inhibition and Patient Outcomes (PLATO) trial."5.38Angiotensin receptor blockers worsen renal function and dyspnea on ticagrelor: a potential ticagrelor-angiotensin receptor blocker interaction? ( DiNicolantonio, JJ; Serebruany, VL, 2012)
"In acute coronary syndrome patients with chronic kidney disease, ticagrelor compared with clopidogrel significantly reduces ischemic end points and mortality without a significant increase in major bleeding but with numerically more non-procedure-related bleeding."5.14Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial. ( Aylward, P; Buck, KK; Budaj, A; Cannon, CP; Cornel, JH; Harrington, RA; Horrow, J; James, S; Katus, H; Keltai, M; Lewis, BS; Parikh, K; Storey, RF; Szummer, K; Wallentin, L; Wojdyla, D, 2010)
"The present review focuses on the roles of thromboxane A2 (TxA2) in arterial thrombosis, atherogenesis, vascular stent-related ischemic events and renal proteinuria."4.85Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases. ( Alberts, P; Bounameaux, H; Fontana, P; Mann, J; Sakariassen, KS; Sorensen, AS, 2009)
"Although aspirin-clopidogrel combination is more useful for acute coronary syndrome (ACS), the renal safety of this combination had not been established."3.83Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome. ( Baber, M; HamidAkash, MS; Hussain, SB; Irfan, M; Qadir, MI; Rehman, A, 2016)
"Our aim was to identify risk factors for acute gastrointestinal (GI) bleeding in patients with myocardial infarction (MI) who were prescribed clopidogrel following hospital discharge."3.80Risk factors for acute gastrointestinal bleeding following myocardial infarction in veteran patients who are prescribed clopidogrel. ( Cuschieri, JR; Drawz, P; Falck-Ytter, Y; Wong, RC, 2014)
" We report a case of a large renal hematoma following SWL that resulted in nephrectomy in a type 2 diabetic patient with primary hyperparathyroidism using clopidogrel due to coronary heart disease CHD."3.73Serious clopidogrel associated renal hematoma in a type 2 diabetic patient with primary hyperparathyroidism after extracorporeal shock wave lithotripsy. ( Agil, C; Akay, F; Akay, H; Bahceci, M; Tuzcu, A, 2005)
" A low postoperative dose of aprotinin in patients receiving clopidogrel is safe and has comparable effects regarding postoperative bleeding complications as a high dose."2.75Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study. ( Istad, R; Ringdal, MA; Tangen, G; Tølløfsrud, S; Øvrum, E; Øystese, R, 2010)
"Ticagrelor is a new antiplatelet agent that was pitted against clopidogrel in the Platelet Inhibition and Patient Outcomes (PLATO) trial."1.38Angiotensin receptor blockers worsen renal function and dyspnea on ticagrelor: a potential ticagrelor-angiotensin receptor blocker interaction? ( DiNicolantonio, JJ; Serebruany, VL, 2012)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.34)18.2507
2000's11 (37.93)29.6817
2010's15 (51.72)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qadir, MI1
Rehman, A1
HamidAkash, MS1
Irfan, M1
Baber, M1
Hussain, SB1
Baber, U1
Bander, J1
Karajgikar, R1
Yadav, K1
Hadi, A1
Theodoropolous, K1
Gukathasan, N1
Roy, S1
Sayeneni, S1
Scott, SA1
Kovacic, JC1
Yu, J1
Sartori, S1
Mehran, R1
Uribarri, J1
Badimon, JJ1
Muntner, P1
Moreno, P1
Kini, AS1
Sharma, SK1
Cuschieri, JR1
Drawz, P1
Falck-Ytter, Y1
Wong, RC1
Ozyalvacli, ME1
Uyeturk, U1
Halicioglu, S1
Kargı, E1
Guo, LZ1
Kim, MH1
Kim, TH1
Park, JS1
Jin, E1
Shim, CH1
Choi, SY1
Serebruany, VL2
Eusebi, LH1
Rabitti, S1
Artesiani, ML1
Gelli, D1
Montagnani, M1
Zagari, RM1
Bazzoli, F1
Sakariassen, KS1
Alberts, P1
Fontana, P1
Mann, J1
Bounameaux, H1
Sorensen, AS1
Øvrum, E1
Tangen, G1
Tølløfsrud, S1
Ringdal, MA1
Øystese, R1
Istad, R1
James, S1
Budaj, A1
Aylward, P1
Buck, KK1
Cannon, CP1
Cornel, JH1
Harrington, RA1
Horrow, J1
Katus, H1
Keltai, M1
Lewis, BS1
Parikh, K1
Storey, RF1
Szummer, K1
Wojdyla, D1
Wallentin, L1
Park, KW1
Park, JJ1
Jeon, KH1
Kang, SH1
Oh, IY1
Yang, HM1
Cho, HJ1
Lee, HY1
Kang, HJ1
Koo, BK1
Oh, BH1
Park, YB1
Kim, HS1
Hayashi, K1
Ohtsu, F1
Yano, R1
Sakakibara, J1
Goto, N1
Htun, P1
Fateh-Moghadam, S1
Bischofs, C1
Banya, W1
Müller, K1
Bigalke, B1
Stellos, K1
May, AE1
Flather, M1
Gawaz, M1
Geisler, T1
Basra, SS1
Tsai, P1
Lakkis, NM1
Woo, JS1
Kim, W1
Lee, SR1
Jung, KH1
Kim, WS1
Lew, JH1
Lee, TW1
Lim, CK1
Choi, YH1
Suh, SH1
Choi, JS1
Kim, CS1
Sim, DS1
Bae, EH1
Lim, SY1
Ma, SK1
Jeong, MH1
Kim, SW1
DiNicolantonio, JJ1
Fernandez, JS1
Sadaniantz, BT1
Sadaniantz, A1
Bahceci, M1
Tuzcu, A1
Akay, F1
Agil, C1
Akay, H1
Ohtake, T1
Kobayashi, S1
Okamoto, K1
Oka, M1
Maesato, K1
Yasu, T1
Moriya, H1
Otrock, ZK1
Sawaya, JI1
Zebian, RC1
Taher, AT1
de Silva, R1
Nikitin, NP1
Witte, KK1
Rigby, AS1
Loh, H1
Nicholson, A1
Bhandari, S1
Clark, AL1
Cleland, JG1
Dorval, JF1
Soulez, G1
Berry, C1
Bonan, R1
Tu, X1
Chen, X1
Xie, Y1
Shi, S1
Wang, J1
Chen, Y1
Li, J1
Vyas, S1
Roberti, I1
McCarthy, C1
Zauner, C1
Funk, GC1
Birnbacher, R1
Zoja, C3
Perico, N3
Remuzzi, G3
Bertani, T2
Bergamelli, A1
Pasini, M1
Morigi, M1
Dadan, J1
Belloni, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised, Double-blind, Parallel Group, Phase 3, Efficacy and Safety Study of Ticagrelor Compared With Clopidogrel for Prevention of Vascular Events in Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS) [PLATO- a Study of PLATelet Inh[NCT00391872]Phase 318,624 participants (Actual)Interventional2006-10-31Completed
Evaluation of Platelet Aggregation and Adenosine Levels in Patients With Coronary Artery Disease and Chronic Kidney Dysfunction Taking Dual Antiplatelet Therapy With Aspirin and Clopidogrel or Ticagrelor[NCT03039205]Phase 290 participants (Actual)Interventional2017-11-07Completed
DPP-4 Inhibitors in Patients With Type 2 Diabetes and Acute Myocardial Infarction:Effects on Platelet Function[NCT02377388]Phase 374 participants (Actual)Interventional2017-02-07Completed
Platelet Reactivity in Patients With Chronic Kidney Disease Receiving Adjunctive Cilostazol Compared to a High-maintenance Dose of Clopidogrel[NCT01328470]Phase 485 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Participants With Any Event From the Composite of All-cause Mortality, MI, and Stroke

Participants with death from any cause, MI, or stroke. If no event, censoring occurs at the earliest of patient withdrawal of consent or date of scheduled withdrawal from therapy. ITT analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR901
CLOPIDOGREL1065

Participants With Any Event From the Composite of Death From Vascular Causes, MI (Including Silent), Stroke, Recurrent Ischemia, Transient Ischemic Attack (TIA) and Other Arterial Thrombotic Events.

Participants with death from vascular causes, MI, stroke, recurrent ischemia, or other thrombotic events. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT analysis of whole population. Events were adjudicated. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR1290
CLOPIDOGREL1456

Participants With Any Event From the Composite of Death From Vascular Causes, MI, and Stroke for the Subgroup of Patients With Intent for Invasive Management at Randomization

Participants with death from vascular causes, MI, or stroke. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT analysis of intent for invasive management population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR569
CLOPIDOGREL668

Participants With Any Event From the Composite of Death From Vascular Causes, Myocardial Infarction (MI), and Stroke

Participants with death from vascular causes, MI, or stroke. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. Intention To Treat (ITT) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR864
CLOPIDOGREL1014

Participants With Any Major Bleeding Event

Participants with major (fatal/life-threatening or other) bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR961
CLOPIDOGREL929

Participants With Coronary Artery Bypass Graft (CABG) Major Bleeding

Participants with a major CABG-related bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. All CABG surgeries were submitted for adjudication by an endpoint committee as potential bleeds. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR619
CLOPIDOGREL654

Participants With Coronary Artery Bypass Graft (CABG) Major Fatal/Life-threatening Bleeding

Number of participants with a major fatal/life-threatening CABG-related bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. All CABG surgeries were submitted for adjudication by an endpoint committee as potential bleeds. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR329
CLOPIDOGREL341

Participants With Death From Any Cause

Participants with death from any cause. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR399
CLOPIDOGREL506

Participants With Death From Vascular Causes

Participants with death from vascular causes. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR353
CLOPIDOGREL442

Participants With Major or Minor Bleeding

Participants with major (fatal/life-threatening or other) or minor bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR1339
CLOPIDOGREL1215

Participants With MI Event

Participants with MI event. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR504
CLOPIDOGREL593

Participants With Non-CABG (Coronary Artery Bypass Graft) Related Major Bleeding

Participants with non CABG related major (fatal/life-threatening or other) bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR362
CLOPIDOGREL306

Participants With Non-procedural Major Bleeding

Participants with non-procedural major bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR235
CLOPIDOGREL180

Participants With Stroke

Participants with stroke. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR125
CLOPIDOGREL106

Participants With Ventricular Pauses of Greater Than or Equal to 3 Seconds in Patients Monitored by Holter 24 Hour ECG Recorders for 1 Week at 1 Month Following Randomization

Number of participants who were observed to have at least 1 ventricular pause of at least 3 seconds. Population is all patients who were observed over 2 week-long periods. Pauses were flagged algorithmically and confirmed by TIMI cardiologists. (NCT00391872)
Timeframe: 1-week period following randomization

InterventionParticipants (Number)
TICAGRELOR21
CLOPIDOGREL16

Participants With Ventricular Pauses of Greater Than or Equal to 3 Seconds in Patients Monitored by Holter 24-hour ECG Recorders for 1 Week Following Randomization

Number of participants who were observed to have at least 1 ventricular pause of at least 3 seconds. Population is all patients who were observed over 2 week-long periods. Pauses were flagged algorithmically and confirmed by Thrombolysis in Myocardial Infarction (TIMI) group cardiologists. (NCT00391872)
Timeframe: 1-week period following randomization

InterventionParticipants (Number)
TICAGRELOR84
CLOPIDOGREL51

Reviews

5 reviews available for ticlopidine and Kidney Diseases

ArticleYear
Proton pump inhibitors: Risks of long-term use.
    Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:7

    Topics: Calcium; Cardiovascular Diseases; Clopidogrel; Dementia; Drug Interactions; Fractures, Bone; Gastroi

2017
Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases.
    Future cardiology, 2009, Volume: 5, Issue:5

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Humans;

2009
Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.
    Journal of the American College of Cardiology, 2011, Nov-22, Volume: 58, Issue:22

    Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chronic Disease; Clinical Trials as Topic; Clopidogrel;

2011
Review of antithrombotic agents used for acute coronary syndromes in renal patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:3

    Topics: Acute Disease; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Fib

2003
Antiplatelet agents: effects on the progressive renal disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 17, Issue:5 Suppl 1

    Topics: Animals; Anticoagulants; Blood Platelets; Humans; Kidney; Kidney Diseases; Platelet Aggregation Inhi

1991

Trials

4 trials available for ticlopidine and Kidney Diseases

ArticleYear
Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study.
    Interactive cardiovascular and thoracic surgery, 2010, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aprotinin; Blood Transfusion; Cerebrovascular Disorders; Clopidogrel

2010
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
    Circulation, 2010, Sep-14, Volume: 122, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Fem

2010
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
    Circulation, 2010, Sep-14, Volume: 122, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Fem

2010
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
    Circulation, 2010, Sep-14, Volume: 122, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Fem

2010
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
    Circulation, 2010, Sep-14, Volume: 122, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Fem

2010
Platelet reactivity in patients with chronic kidney disease receiving adjunctive cilostazol compared with a high-maintenance dose of clopidogrel: results of the effect of platelet inhibition according to clopidogrel dose in patients with chronic kidney di
    American heart journal, 2011, Volume: 162, Issue:6

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Chronic Disease; Cilostazol; Clopidogrel; Coronary Arte

2011
Triple vs. dual antiplatelet therapy in patients with acute myocardial infarction and renal dysfunction.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:10

    Topics: Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Disease-Free Survival; Drug Therapy, Comb

2012

Other Studies

20 other studies available for ticlopidine and Kidney Diseases

ArticleYear
Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:6

    Topics: Acute Coronary Syndrome; Aspirin; Biomarkers; Blood Urea Nitrogen; Clopidogrel; Creatinine; Drug The

2016
Combined and independent impact of diabetes mellitus and chronic kidney disease on residual platelet reactivity.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:1

    Topics: Aged; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Female; Humans; Kidney Diseases; Male;

2013
Risk factors for acute gastrointestinal bleeding following myocardial infarction in veteran patients who are prescribed clopidogrel.
    Journal of digestive diseases, 2014, Volume: 15, Issue:4

    Topics: Acute Disease; Age Factors; Aged; Anticoagulants; Chronic Disease; Clopidogrel; Female; Gastrointest

2014
Spontaneous renal parenchymal hematoma associated with clopidogrel in a patient with diabetic nephropathy.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:2

    Topics: Aged; Clopidogrel; Diabetic Nephropathies; Hematoma; Humans; Kidney Diseases; Male; Platelet Aggrega

2015
Comparison of Three Tests to Distinguish Platelet Reactivity in Patients with Renal Impairment during Dual Antiplatelet Therapy.
    Nephron, 2016, Volume: 132, Issue:3

    Topics: Aged; Aspirin; Clopidogrel; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Hemorrhage;

2016
Clinical predictors of high posttreatment platelet reactivity to clopidogrel in Koreans.
    Cardiovascular therapeutics, 2012, Volume: 30, Issue:1

    Topics: Age Factors; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Asian People; Biomarkers; B

2012
[Risk factors and subjective symptoms of drug-induced leucopenia].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:1

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Autoimmune Dise

2011
Low responsiveness to clopidogrel increases risk among CKD patients undergoing coronary intervention.
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chronic Disease; Clopidogrel; Cohort Studies; Coronar

2011
Angiotensin receptor blockers worsen renal function and dyspnea on ticagrelor: a potential ticagrelor-angiotensin receptor blocker interaction?
    Clinical cardiology, 2012, Volume: 35, Issue:11

    Topics: Adenosine; Angiotensin II Type 1 Receptor Blockers; Clopidogrel; Drug Interactions; Dyspnea; Glomeru

2012
Serious clopidogrel associated renal hematoma in a type 2 diabetic patient with primary hyperparathyroidism after extracorporeal shock wave lithotripsy.
    Saudi medical journal, 2005, Volume: 26, Issue:6

    Topics: Clopidogrel; Diabetes Mellitus, Type 2; Hematoma; Humans; Hyperparathyroidism, Primary; Kidney Calcu

2005
Ticlopidine-induced lupus with renal involvement.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:7

    Topics: Aged; Fibrinolytic Agents; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Lupus Erythematosus,

2006
Spontaneous abdominal hematoma in a patient treated with clopidogrel and aspirin.
    Annals of hematology, 2006, Volume: 85, Issue:10

    Topics: Abdominal Cavity; Abdominal Pain; Aged; Aspirin; Clopidogrel; Hematoma; Humans; Kidney Diseases; Mal

2006
Effects of applying a standardised management algorithm for moderate to severe renal dysfunction in patients with chronic stable heart failure.
    European journal of heart failure, 2007, Volume: 9, Issue:4

    Topics: Aged; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Creatinine; Female

2007
Management of a spontaneous renal capsule hematoma following cardiac catheterization involving use of a platelet glycoprotein IIb/IIIa inhibitor: a case report.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Jun-01, Volume: 69, Issue:7

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Catheterization; Clopidogrel; Cor

2007
Anti-inflammatory renoprotective effect of clopidogrel and irbesartan in chronic renal injury.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biphenyl Compounds; Blood

2008
2007 Focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Jan-01, Volume: 71, Issue:1

    Topics: Acute Coronary Syndrome; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin;

2008
May-Thurner syndrome in a pediatric renal transplant recipient--case report and literature review.
    Pediatric transplantation, 2008, Volume: 12, Issue:6

    Topics: Adolescent; Clopidogrel; Creatinine; Edema; Female; Graft Survival; Humans; Iliac Vein; Kidney Disea

2008
Platelet aggregation inhibition with ticlopidine in the treatment of stroke.
    Intensive care medicine, 2001, Volume: 27, Issue:3

    Topics: Acute Disease; Critical Care; Drug Eruptions; Drug Monitoring; Gastrointestinal Diseases; Humans; Ki

2001
Effect of ticlopidine on the evolution of renal disease in rats with reduced renal mass.
    Contributions to nephrology, 1990, Volume: 81

    Topics: Adenosine Diphosphate; Animals; Bleeding Time; Kidney; Kidney Diseases; Male; Organ Size; Platelet A

1990
Ticlopidine prevents renal disease progression in rats with reduced renal mass.
    Kidney international, 1990, Volume: 37, Issue:3

    Topics: Animals; Biphenyl Compounds; Bleeding Time; Blood Pressure; Hematocrit; Heptanoic Acids; Infarction;

1990