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ticlopidine and Ischemic Attack, Transient

ticlopidine has been researched along with Ischemic Attack, Transient in 256 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
" The trial was halted after 84% of the anticipated number of patients had been enrolled because the data and safety monitoring board had determined that the combination of clopidogrel and aspirin was associated with both a lower risk of major ischemic events and a higher risk of major hemorrhage than aspirin alone at 90 days."9.27Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. ( Barsan, W; Conwit, RA; Easton, JD; Elm, JJ; Farrant, M; Johnston, SC; Kim, AS; Lindblad, AS; Palesch, YY, 2018)
"Rationale and aim Little is known about the safety and efficacy of the combination of ticagrelor and aspirin in acute ischemic stroke."9.24Effect of ticagrelor with clopidogrel on high on-treatment platelet reactivity in acute stroke or transient ischemic attack (PRINCE) trial: Rationale and design. ( Cao, Y; Chen, G; Chen, W; Li, H; Li, J; Li, X; Lin, Y; Liu, L; Meng, X; Pan, Y; Wang, D; Wang, Y; Wang, Z; Wu, J; Xu, Y; Zhang, G; Zhao, X, 2017)
"The aim of this study was to analyze the benefits and safety associated with the combination therapy of clopidogrel and aspirin among minor stroke or transient ischemic attack patients treated within 12 hours."9.22Treatment Effect of Clopidogrel Plus Aspirin Within 12 Hours of Acute Minor Stroke or Transient Ischemic Attack. ( Jing, J; Johnston, SC; Li, H; Li, Z; Liu, L; Meng, X; Pan, Y; Wang, C; Wang, D; Wang, X; Wang, Y; Xian, Y; Yang, X; Zhang, C; Zhao, X, 2016)
"Patients with acute minor ischemic stroke or transient ischemic attack in the trial were randomized to treatment with clopidogrel combined with aspirin or to aspirin alone."9.22Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack. ( Johnston, SC; Li, H; Lin, J; Lin, Y; Liu, L; Meng, X; Pan, Y; Wang, C; Wang, D; Wang, Y; Xu, J; Zhao, X, 2016)
"Dual clopidogrel-aspirin therapy was associated with a marked reduction in new strokes compared with the therapy of aspirin alone in patients with normal renal function (hazard ratio, 0."9.22Effect of Estimated Glomerular Filtration Rate Decline on the Efficacy and Safety of Clopidogrel With Aspirin in Minor Stroke or Transient Ischemic Attack: CHANCE Substudy (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events). ( Johnston, SC; Li, H; Liu, L; Meng, X; Pan, Y; Wang, C; Wang, D; Wang, Y; Wu, Y; Zhao, X; Zhou, Y, 2016)
"The Clopidogrel in High-risk patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial showed that the combined treatment of clopidogrel and aspirin decreases the 90-day risk of stroke without increasing hemorrhage in comparison with aspirin alone, but provided insufficient data to establish whether the benefit persisted over a longer period of time beyond the trial termination."9.20Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes. ( Johnston, SC; Li, H; Liu, L; Meng, X; Pan, Y; Wang, A; Wang, C; Wang, D; Wang, Y; Zhao, X, 2015)
"We compared the effect of clopidogrel plus aspirin vs aspirin alone on functional outcome and quality of life in the Clopidogrel in High-risk Patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial of aspirin-clopidogrel vs aspirin alone after acute minor stroke or TIA."9.20Effect of clopidogrel with aspirin on functional outcome in TIA or minor stroke: CHANCE substudy. ( Fang, J; Hu, B; Johnston, SC; Li, H; Liu, L; Meng, X; Wang, A; Wang, C; Wang, D; Wang, X; Wang, Y; Xian, Y; Zhao, X, 2015)
"To study whether Clopidogrel-Aspirin combined treatment for high risk transient ischaemic attack (TIA) or minor stroke results in increased number of lesions associated with anti-thrombotic cerebral haemorrhage or cerebral micro-bleeds (CMB) than aspirin alone treatment."9.20Combined clopidogrel-aspirin treatment for high risk TIA or minor stroke does not increase cerebral microbleeds. ( Wang, P; Wang, Y; Wang, Z; Xin, H; Xu, C, 2015)
"Among patients with TIA or minor stroke who can be treated within 24 hours after the onset of symptoms, the combination of clopidogrel and aspirin is superior to aspirin alone for reducing the risk of stroke in the first 90 days and does not increase the risk of hemorrhage."9.17Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. ( Cui, L; Dong, Q; Jia, J; Johnston, SC; Li, H; Li, Y; Liu, L; Meng, X; Wang, C; Wang, D; Wang, Y; Wang, Z; Xia, H; Xu, A; Zeng, J; Zhao, X, 2013)
"We evaluated treatment effects of ticagrelor versus clopidogrel in patients with acute coronary syndrome with and without a history of prior stroke or TIA in the PLATelet inhibition and patient Outcomes (PLATO) trial."9.16Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. ( Becker, RC; Husted, S; James, SK; Keltai, M; Khurmi, NS; Lopes, RD; Lopez-Sendon, JL; Mahaffey, KW; Maya, J; Morais, J; Nicolau, JC; Pais, P; Raev, D; Stevens, SR; Storey, RF, 2012)
"To determine the prevalence of platelet nonresponsiveness to aspirin treatment for secondary stroke prophylaxis, the authors studied consecutive patients during a 29-month period."9.13Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. ( Bates, V; Forrest, A; Gengo, FM; Gengo, MF; Hourihane, M; Rainka, M; Robson, M, 2008)
"The CAPRIE study showed the superiority of clopidogrel over acetylsalicylic acid (ASA) for reducing the combined risk of major atherothrombotic events in patients with recent myocardial infarction (MI), recent ischaemic stroke (IS) or established peripheral arterial disease."9.11Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH): study design and baseline data. ( Bogousslavsky, J; Brass, LM; Cimminiello, C; Csiba, L; Diener, HC; Kaste, M; Leys, D; Matias-Guiu, J; Rupprecht, HJ, 2004)
"Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) is a randomized, double-blind study in subjects with recently symptomatic > or =50% carotid stenosis."9.11Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial. ( Droste, DW; Kaps, M; Larrue, V; Lees, KR; Markus, HS; Ringelstein, EB; Siebler, M, 2005)
"To compare the efficacy and safety of two antiplatelet regimens, ticlopidine alone (200 mg daily) and ticlopidine (100 mg daily) plus aspirin (81 mg daily), in patients with ischemic stroke from the Tokai district of Japan."9.10Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke. ( Ito, E; Kuzuhara, S; Nakajima, M; Takahashi, A; Uchiyama, S; Yamamoto, H, 2003)
"The Swedish Ticlopidine Multicentre Study (STIMS) was a double-blind placebo-controlled trial designed to determine whether ticlopidine, a platelet antiaggregatory agent, reduces the incidence of myocardial infarction, stroke and transitory ischaemic attacks in patients with intermittent claudication."9.06Prevention of myocardial infarction and stroke in patients with intermittent claudication; effects of ticlopidine. Results from STIMS, the Swedish Ticlopidine Multicentre Study. ( Almgren, B; Bergqvist, D; Boberg, J; Boberg, M; Eriksson, I; Fagher, B; Janzon, L; Kjellström, T; Lindgärde, F; Persson, G, 1990)
"Optimal antiplatelet therapy after an ischemic stroke or transient ischemic attack while on aspirin is uncertain."8.95Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis. ( Hong, KS; Lee, M; Ovbiagele, B; Rao, NM; Saver, JL; Wu, YL, 2017)
"The association of genetic polymorphisms and clopidogrel efficacy in patients with ischemic stroke or transient ischemic attack (TIA) remains controversial."8.95Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis. ( Chen, W; Han, Y; Huang, L; Johnston, SC; Li, X; Liu, L; Pan, Y; Wang, G; Wang, Y; Xu, Y; Yang, Q; Yi, X; Zhang, Q; Zhao, X, 2017)
"Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel for 90 days was recommended as the secondary prevention of minor ischaemic strokes or transient ischaemic attacks (TIAs) in 2014."8.93Dual antiplatelet therapy after stroke or transient ischaemic attack - how long to treat? The duration of aspirin plus clopidogrel in stroke or transient ischaemic attack: a systematic review and meta-analysis. ( Chang, T; Ge, F; Guo, R; Li, M; Lin, H; Liu, Y; Ruan, Z, 2016)
"Compared with monotherapy, short-term aspirin in combination with clopidogrel is more effective as secondary prevention of stroke or TIA without increasing the risk of hemorrhagic stroke and major bleeding events."8.91Aspirin plus clopidogrel as secondary prevention after stroke or transient ischemic attack: a systematic review and meta-analysis. ( Li, J; Li, Y; Shang, X; Wang, C; Yan, C; Zhang, L; Zhang, Q; Zheng, M, 2015)
"The safety and efficacy of dual antiplatelet therapy (DAPT) with aspirin and clopidogrel in the setting of secondary stroke prevention are reviewed."8.91Dual antiplatelet therapy with clopidogrel and aspirin after ischemic stroke: A review of the evidence. ( Davis, KA; Dietrich, E; Miyares, MA, 2015)
"To present the systematic assessment on the efficacy and bleeding adverse events of dual-antiplatelet therapy with aspirin and clopidogrel versus aspirin-mono-antiplatelet therapy in patients with ischemic stroke or transient ischemic attack."8.91[Meta-analysis on the efficacy and adverse events of aspirin plus clopidogrel versus aspirin-monotherapy in patients with ischemic stroke or transient ischemic attack]. ( Gao, P; Hu, Y; Qian, J; Tang, X; Yang, C, 2015)
"Literature is scarce regarding the use of clopidogrel during pregnancy and the potential hazard to maternal and fetal health."8.90Successful gestation and delivery using clopidogrel for secondary stroke prophylaxis: a case report and literature review. ( Cuesta-Fernandez, A; Kayaleh, OR; Reilly, CR, 2014)
"Given the high risk of stroke after TIA (transient ischemia attack) or stroke and the adverse reaction of bleeding of antiplatelets, we undertook a meta-analysis, reviewed randomized controlled trials (RCTs) comparing aspirin plus clopidogrel with aspirin alone to determine the efficacy and adverse reaction of bleeding of the two protocols in the prevention of stroke."8.89The efficacy and adverse reaction of bleeding of clopidogrel plus aspirin as compared to aspirin alone after stroke or TIA: a systematic review. ( Hu, B; Huang, Y; Li, JY; Li, M; Mao, L; Xia, YP, 2013)
"Bleeding is the most common adverse reaction to aspirin and can lead to drug discontinuation or even be life-threatening in the secondary prevention of stroke or transient ischemic attack."8.12Effect of body weight on bleeding events of aspirin in ischemic stroke or transient ischemic attack patients. ( Cheng, J; Deng, X; Li, H; Ma, Y; Shi, T; Wang, X; Wu, Y; Zhang, Z; Zhu, Q, 2022)
"The relationship of CYP2C19 genotype and clinical efficacy in stroke or transient ischemic attack (TIA) patients treated with clopidogrel monotherapy or clopidogrel plus aspirin remains unknown."7.88Efficacy and safety of CYP2C19 genotype in stroke or transient ischemic attack patients treated with clopidogrel monotherapy or clopidogrel plus aspirin: Protocol for a systemic review and meta-analysis. ( Cui, M; Gu, ZC; Li, WY; Pan, MM; Yao, JC, 2018)
"Clopidogrel HTPR does not seem to be a major contributor to recurrent ischemic events in Danish ischemic stroke patients."7.88Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response. ( Jørgensen, NR; Rath, CL; Wienecke, T, 2018)
"Among patients in the CHAMPION trials with a prior cerebrovascular event at least 1 year before the percutaneous coronary intervention, the efficacy and bleeding profile of cangrelor compared with clopidogrel was similar to that in the overall trial."7.85Impact of Cerebrovascular Events Older Than One Year on Ischemic and Bleeding Outcomes With Cangrelor in Percutaneous Coronary Intervention. ( Bhatt, DL; Deliargyris, EN; Gibson, CM; Hamm, CW; Harrington, RA; Mahaffey, KW; Prats, J; Price, MJ; Sawlani, NN; Steg, PG; Stone, GW; White, HD, 2017)
"The objective of this study was to compare nonresponders (NR) and responders (R) to clopidogrel with respect to presence of microvascular and macrovascular pathology in a cohort of patients with recent minor ischemic stroke (IS) or transient ischemic attack (TIA)."7.81Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease. ( Gigante, B; Höeg Dembrower, K; Jörneskog, G; Laska, AC; Laurencikas, E; Lundström, A; von Arbin, M; Wallén, H, 2015)
"The relation between high on-treatment platelet reactivity (HPR), and the level of glucose intolerance and insulin resistance (IR) was studied in clopidogrel-treated patients with minor ischemic stroke or TIA."7.80Glucose intolerance and insulin resistance as predictors of low platelet response to clopidogrel in patients with minor ischemic stroke or TIA. ( Jörneskog, G; Laska, AC; Lundström, A; Von Arbin, M; Wallén, H, 2014)
"Japanese guidelines recommend aspirin 160-300 mg/day, starting within 48 h, for patients with acute cerebral infarction."7.80Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. ( Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T, 2014)
"Treatment with the combination of clopidogrel and aspirin taken soon after a transient ischemic attack (TIA) or minor stroke was shown to reduce the 90-day risk of stroke in a large trial in China, but the cost-effectiveness is unknown."7.80Cost-effectiveness of clopidogrel-aspirin versus aspirin alone for acute transient ischemic attack and minor stroke. ( Johnston, SC; Liu, G; Liu, L; Meng, X; Pan, Y; Wang, A; Wang, C; Wang, Y; Zhao, K; Zhao, X, 2014)
"To examine healthcare costs among patients hospitalized for transient ischemic attack or ischemic stroke (TIA/stroke) and prescribed aspirin plus extended-release dipyridamole (ASA-ERDP) or clopidogrel (CLOPID) within 30 days post-discharge using a retrospective claims database from a large US managed care organization."7.78One-year follow-up healthcare costs of patients hospitalized for transient ischemic attack or ischemic stroke and discharged with aspirin plus extended-release dipyridamole or clopidogrel. ( Burton, TM; Lacey, M; Lang, K; Liu, F; Monsalvo, ML; Sander, S; Yu, Y, 2012)
" In this study, the authors assess the incidence of stroke or transient ischemic attack (TIA) following discontinuation of a 6-week course of clopidogrel in patients with cerebral aneurysms treated with stent-assisted techniques."7.78Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques. ( Abel, TJ; Chalouhi, N; Hasan, DM; Jabbour, PM; Kung, DK; Rossen, JD; Thomas, J; Wassef, SN, 2012)
"Aspirin plus clopidogrel (A+C) may be more effective than aspirin only (AO) acutely after TIA and minor stroke, but the risk of bleeding in the acute phase is uncertain."7.76Preliminary evidence of a high risk of bleeding on aspirin plus clopidogrel in aspirin-naïve patients in the acute phase after TIA or minor ischaemic stroke. ( Buchan, AM; Chandratheva, A; Geraghty, OC; Kennedy, J; Marquardt, L; Rothwell, PM, 2010)
"The combination of aspirin and clopidogrel is indicated after acute coronary events and possibly for a short period after TIA or minor ischemic stroke."7.76Low risk of rebound events after a short course of clopidogrel in acute TIA or minor stroke. ( Chandratheva, A; Geraghty, OC; Paul, NL; Rothwell, PM, 2010)
"To report a case of ticlopidine-induced neutropenia occurring 18 days after discontinuation of the drug."7.69Delayed neutropenia with ticlopidine. ( Farver, DK; Hansen, LA, 1994)
" The number of patients with adverse events and bleeding complications, and their severity, were significantly greater in the triple therapy group (p<0."6.73A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility. ( Bath, PM; England, T; Gray, LJ; Sare, GM; Sprigg, N; Willmot, MR; Zhao, L, 2008)
" Although administration of antiplatelet agents has been confirmed to be one of the major approaches for secondary prevention of noncardioembolic stroke, the short-term or long-term use of aspirin plus clopidogrel for secondary stroke prevention remains to be controversial."6.52Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention. ( Chen, W; Wang, Y, 2015)
"Aspirin has been convincingly shown to reduce stroke and death in men with transient ischemic attacks (it may possibly be beneficial to women also), myocardial infarction and death in patients with unstable angina, thromboembolic complications associated with artificial heart valves in patients receiving oral anticoagulants (although gastrointestinal bleeding is prohibitive with this combination), and thrombotic occlusion of silicone rubber arteriovenous cannulae in uremic patients undergoing hemodialysis."6.15Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. ( Harker, LA, 1986)
"Minor stroke and transient ischemic attack are common disorders with high rate of subsequent disabling stroke."5.43High-Sensitive C-Reactive Protein Predicts Recurrent Stroke and Poor Functional Outcome: Subanalysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events Trial. ( Li, J; Lin, J; Liu, L; Meng, X; Wang, A; Wang, C; Wang, Y; Zhao, X, 2016)
" The trial was halted after 84% of the anticipated number of patients had been enrolled because the data and safety monitoring board had determined that the combination of clopidogrel and aspirin was associated with both a lower risk of major ischemic events and a higher risk of major hemorrhage than aspirin alone at 90 days."5.27Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. ( Barsan, W; Conwit, RA; Easton, JD; Elm, JJ; Farrant, M; Johnston, SC; Kim, AS; Lindblad, AS; Palesch, YY, 2018)
"Rationale and aim Little is known about the safety and efficacy of the combination of ticagrelor and aspirin in acute ischemic stroke."5.24Effect of ticagrelor with clopidogrel on high on-treatment platelet reactivity in acute stroke or transient ischemic attack (PRINCE) trial: Rationale and design. ( Cao, Y; Chen, G; Chen, W; Li, H; Li, J; Li, X; Lin, Y; Liu, L; Meng, X; Pan, Y; Wang, D; Wang, Y; Wang, Z; Wu, J; Xu, Y; Zhang, G; Zhao, X, 2017)
"The aim of this study was to compare aspirin plus clopidogrel with aspirin alone as antithrombotic treatment following transcatheter aortic valve replacement (TAVR) for the prevention of ischemic events, bleeding events, and death."5.24Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomi ( Al-Qoofi, F; Chamandi, C; Côté, M; Dumont, E; Garcia Del Blanco, B; Généreux, P; Maluenda, G; Masson, JB; Paradis, JM; Pelletier, M; Rodés-Cabau, J; Serra, V; Thoenes, M; Webb, JG; Welsh, RC, 2017)
"Clopidogrel is an antiplatelet agent recommended for secondary prevention of ischemic stroke (IS) and transient ischemic attack (TIA)."5.22The role of ( Bath, PM; Leach, M; McDermott, JH; Newman, WG; Sen, D; Smith, CJ, 2022)
"The aim of this study was to analyze the benefits and safety associated with the combination therapy of clopidogrel and aspirin among minor stroke or transient ischemic attack patients treated within 12 hours."5.22Treatment Effect of Clopidogrel Plus Aspirin Within 12 Hours of Acute Minor Stroke or Transient Ischemic Attack. ( Jing, J; Johnston, SC; Li, H; Li, Z; Liu, L; Meng, X; Pan, Y; Wang, C; Wang, D; Wang, X; Wang, Y; Xian, Y; Yang, X; Zhang, C; Zhao, X, 2016)
"Patients with acute minor ischemic stroke or transient ischemic attack in the trial were randomized to treatment with clopidogrel combined with aspirin or to aspirin alone."5.22Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack. ( Johnston, SC; Li, H; Lin, J; Lin, Y; Liu, L; Meng, X; Pan, Y; Wang, C; Wang, D; Wang, Y; Xu, J; Zhao, X, 2016)
"Dual clopidogrel-aspirin therapy was associated with a marked reduction in new strokes compared with the therapy of aspirin alone in patients with normal renal function (hazard ratio, 0."5.22Effect of Estimated Glomerular Filtration Rate Decline on the Efficacy and Safety of Clopidogrel With Aspirin in Minor Stroke or Transient Ischemic Attack: CHANCE Substudy (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events). ( Johnston, SC; Li, H; Liu, L; Meng, X; Pan, Y; Wang, C; Wang, D; Wang, Y; Wu, Y; Zhao, X; Zhou, Y, 2016)
"Participants in the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE) trials with HF, but not randomized to oral anticoagulation, were categorized as having preserved versus reduced ejection fraction."5.20Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure. ( Connolly, SJ; Hart, RG; Healey, JS; Hohnloser, SH; McAlister, FA; Pfeffer, MA; Sandhu, RK; Yuan, F; Yusuf, S, 2015)
"The Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events trial randomized minor ischemic stroke or TIA patients to antiplatelet therapy of clopidogrel plus aspirin or aspirin alone."5.20Glycated albumin predicts the effect of dual and single antiplatelet therapy on recurrent stroke. ( Li, J; Lin, J; Liu, L; Wang, A; Wang, C; Wang, D; Wang, Y; Zhao, X, 2015)
"The Clopidogrel in High-risk patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial showed that the combined treatment of clopidogrel and aspirin decreases the 90-day risk of stroke without increasing hemorrhage in comparison with aspirin alone, but provided insufficient data to establish whether the benefit persisted over a longer period of time beyond the trial termination."5.20Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes. ( Johnston, SC; Li, H; Liu, L; Meng, X; Pan, Y; Wang, A; Wang, C; Wang, D; Wang, Y; Zhao, X, 2015)
"We compared the effect of clopidogrel plus aspirin vs aspirin alone on functional outcome and quality of life in the Clopidogrel in High-risk Patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial of aspirin-clopidogrel vs aspirin alone after acute minor stroke or TIA."5.20Effect of clopidogrel with aspirin on functional outcome in TIA or minor stroke: CHANCE substudy. ( Fang, J; Hu, B; Johnston, SC; Li, H; Liu, L; Meng, X; Wang, A; Wang, C; Wang, D; Wang, X; Wang, Y; Xian, Y; Zhao, X, 2015)
"To study whether Clopidogrel-Aspirin combined treatment for high risk transient ischaemic attack (TIA) or minor stroke results in increased number of lesions associated with anti-thrombotic cerebral haemorrhage or cerebral micro-bleeds (CMB) than aspirin alone treatment."5.20Combined clopidogrel-aspirin treatment for high risk TIA or minor stroke does not increase cerebral microbleeds. ( Wang, P; Wang, Y; Wang, Z; Xin, H; Xu, C, 2015)
"We examined the efficacy and safety of dual antiplatelets in patients with transient ischemic attack or minor stroke, defined as National Institute of Health Stroke Scale scores 0-3, in a subgroup analysis of Clopidogrel plus aspirin versus Aspirin alone for Reducing embolization in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR) study."5.19Dual antiplatelets reduce microembolic signals in patients with transient ischemic attack and minor stroke: subgroup analysis of CLAIR study. ( Chen, C; Fu, J; Han, Z; Huang, Y; Lau, AY; Leung, TW; Markus, HS; Ratanakorn, D; Suwanwela, NC; Tan, KS; Wong, KS; Zhao, Y, 2014)
"Among patients with TIA or minor stroke who can be treated within 24 hours after the onset of symptoms, the combination of clopidogrel and aspirin is superior to aspirin alone for reducing the risk of stroke in the first 90 days and does not increase the risk of hemorrhage."5.17Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. ( Cui, L; Dong, Q; Jia, J; Johnston, SC; Li, H; Li, Y; Liu, L; Meng, X; Wang, C; Wang, D; Wang, Y; Wang, Z; Xia, H; Xu, A; Zeng, J; Zhao, X, 2013)
"The aim of POINT is to determine whether clopidogrel plus aspirin taken <12 h after transient ischemic attack or minor ischemic stroke symptom onset is more effective in preventing major ischemic vascular events at 90 days in the high-risk, and acceptably safe, compared with aspirin alone."5.17Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. ( Barsan, W; Battenhouse, H; Conwit, R; Dillon, C; Easton, JD; Elm, J; Farrant, M; Johnston, SC; Lindblad, A; Morgenstern, L; Palesch, Y; Poisson, SN, 2013)
" Patients were assessed at baseline [≤ 4 weeks of transient ischaemic attack (TIA) or ischaemic stroke], and at 14 days and ≥ 90 days after changing treatment from (i) no medication to aspirin monotherapy (N = 26) or (ii) aspirin to clopidogrel monotherapy (N = 22)."5.17High on-treatment platelet reactivity on commonly prescribed antiplatelet agents following transient ischaemic attack or ischaemic stroke: results from the Trinity Antiplatelet Responsiveness (TRAP) study. ( Collins, DR; Coughlan, T; Egan, B; Feeley, TM; Kinsella, JA; McCabe, DJ; Murphy, RP; O'Neill, D; Tierney, S; Tobin, WO, 2013)
"In the PLATelet inhibition and patient Outcomes (PLATO) study, 18 624 patients presenting with acute coronary syndromes randomly received ticagrelor (n=9333) or clopidogrel (n=9291)."5.17Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the PLATO Study. ( Angiolillo, DJ; Ardissino, D; Cannon, CP; Horrow, J; Husted, S; James, SK; Kohli, P; Maurer, G; Morais, J; Nicolau, JC; Oto, A; Reyes, E; Storey, RF; Wallentin, L, 2013)
"We evaluated treatment effects of ticagrelor versus clopidogrel in patients with acute coronary syndrome with and without a history of prior stroke or TIA in the PLATelet inhibition and patient Outcomes (PLATO) trial."5.16Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. ( Becker, RC; Husted, S; James, SK; Keltai, M; Khurmi, NS; Lopes, RD; Lopez-Sendon, JL; Mahaffey, KW; Maya, J; Morais, J; Nicolau, JC; Pais, P; Raev, D; Stevens, SR; Storey, RF, 2012)
"The clopidogrel plus aspirin for infarction reduction in acute stroke or transient ischaemic attack patients with large artery stenosis and microembolic signals (CLAIR) trial was a randomised, open-label, blinded-endpoint trial."5.14Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial. ( Chang, HM; Chen, C; Chollate, P; Fu, J; Han, Z; Hao, Q; Huang, YN; Koh, A; Markus, HS; Ratanakorn, D; Suwanwela, NC; Tan, KS; Wong, KS; Zhao, Y, 2010)
"The study will randomize 5,100 Chinese patients with acute TIA or minor stroke to receive a 3-month regimen of clopidogrel initiated with a loading dose of 300 mg followed by 75 mg/d, combined with aspirin 75 mg/d during the first 21 days, or a 3-month regimen of aspirin 75 mg/d alone."5.14Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event. ( Johnston, SC; Wang, Y, 2010)
"To determine the prevalence of platelet nonresponsiveness to aspirin treatment for secondary stroke prophylaxis, the authors studied consecutive patients during a 29-month period."5.13Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. ( Bates, V; Forrest, A; Gengo, FM; Gengo, MF; Hourihane, M; Rainka, M; Robson, M, 2008)
"Immediately after TIA or minor stroke, patients are at high risk of stroke, which might be reduced by using clopidogrel in addition to aspirin."5.12Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial. ( Buchan, AM; Demchuk, AM; Eliasziw, M; Hill, MD; Kennedy, J; Ryckborst, KJ, 2007)
"The CAPRIE study showed the superiority of clopidogrel over acetylsalicylic acid (ASA) for reducing the combined risk of major atherothrombotic events in patients with recent myocardial infarction (MI), recent ischaemic stroke (IS) or established peripheral arterial disease."5.11Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH): study design and baseline data. ( Bogousslavsky, J; Brass, LM; Cimminiello, C; Csiba, L; Diener, HC; Kaste, M; Leys, D; Matias-Guiu, J; Rupprecht, HJ, 2004)
"Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) is a randomized, double-blind study in subjects with recently symptomatic > or =50% carotid stenosis."5.11Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial. ( Droste, DW; Kaps, M; Larrue, V; Lees, KR; Markus, HS; Ringelstein, EB; Siebler, M, 2005)
"To compare the efficacy and safety of two antiplatelet regimens, ticlopidine alone (200 mg daily) and ticlopidine (100 mg daily) plus aspirin (81 mg daily), in patients with ischemic stroke from the Tokai district of Japan."5.10Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke. ( Ito, E; Kuzuhara, S; Nakajima, M; Takahashi, A; Uchiyama, S; Yamamoto, H, 2003)
"The Swedish Ticlopidine Multicentre Study (STIMS) was a double-blind placebo-controlled trial designed to determine whether ticlopidine, a platelet antiaggregatory agent, reduces the incidence of myocardial infarction, stroke and transitory ischaemic attacks in patients with intermittent claudication."5.06Prevention of myocardial infarction and stroke in patients with intermittent claudication; effects of ticlopidine. Results from STIMS, the Swedish Ticlopidine Multicentre Study. ( Almgren, B; Bergqvist, D; Boberg, J; Boberg, M; Eriksson, I; Fagher, B; Janzon, L; Kjellström, T; Lindgärde, F; Persson, G, 1990)
"For stroke prevention in elderly patients with IS or TIA, DAPT is superior to aspirin monotherapy but appears to be equivalent to clopidogrel monotherapy, and is accompanied by an increased risk of bleeding."4.98Efficacy and safety of dual antiplatelet therapy in the elderly for stroke prevention: a systematic review and meta-analysis. ( Ding, L; Peng, B, 2018)
"Optimal antiplatelet therapy after an ischemic stroke or transient ischemic attack while on aspirin is uncertain."4.95Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis. ( Hong, KS; Lee, M; Ovbiagele, B; Rao, NM; Saver, JL; Wu, YL, 2017)
"The association of genetic polymorphisms and clopidogrel efficacy in patients with ischemic stroke or transient ischemic attack (TIA) remains controversial."4.95Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis. ( Chen, W; Han, Y; Huang, L; Johnston, SC; Li, X; Liu, L; Pan, Y; Wang, G; Wang, Y; Xu, Y; Yang, Q; Yi, X; Zhang, Q; Zhao, X, 2017)
"Cilostazol was significantly more effective than aspirin and clopidogrel alone in the long-term prevention of serious vascular events in patients with prior non-cardioembolic ischaemic stroke or transient ischaemic attack."4.93Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis. ( Guo, ZN; Jin, H; Niu, PP; Xing, YQ; Yang, Y, 2016)
"Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel for 90 days was recommended as the secondary prevention of minor ischaemic strokes or transient ischaemic attacks (TIAs) in 2014."4.93Dual antiplatelet therapy after stroke or transient ischaemic attack - how long to treat? The duration of aspirin plus clopidogrel in stroke or transient ischaemic attack: a systematic review and meta-analysis. ( Chang, T; Ge, F; Guo, R; Li, M; Lin, H; Liu, Y; Ruan, Z, 2016)
"Compared with monotherapy, short-term aspirin in combination with clopidogrel is more effective as secondary prevention of stroke or TIA without increasing the risk of hemorrhagic stroke and major bleeding events."4.91Aspirin plus clopidogrel as secondary prevention after stroke or transient ischemic attack: a systematic review and meta-analysis. ( Li, J; Li, Y; Shang, X; Wang, C; Yan, C; Zhang, L; Zhang, Q; Zheng, M, 2015)
"The safety and efficacy of dual antiplatelet therapy (DAPT) with aspirin and clopidogrel in the setting of secondary stroke prevention are reviewed."4.91Dual antiplatelet therapy with clopidogrel and aspirin after ischemic stroke: A review of the evidence. ( Davis, KA; Dietrich, E; Miyares, MA, 2015)
"To present the systematic assessment on the efficacy and bleeding adverse events of dual-antiplatelet therapy with aspirin and clopidogrel versus aspirin-mono-antiplatelet therapy in patients with ischemic stroke or transient ischemic attack."4.91[Meta-analysis on the efficacy and adverse events of aspirin plus clopidogrel versus aspirin-monotherapy in patients with ischemic stroke or transient ischemic attack]. ( Gao, P; Hu, Y; Qian, J; Tang, X; Yang, C, 2015)
"In the overall population, dual antiplatelet therapy (DAPT) with aspirin and clopidogrel in comparison to aspirin monotherapy reduced the relative risk of total stroke by 20% (risk ratio [RR], 0."4.90Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis. ( Arrich, J; Gouya, G; Gurbel, PA; Huber, K; Pirker-Kees, A; Siller-Matula, JM; Verheugt, FW; Wolzt, M, 2014)
"Literature is scarce regarding the use of clopidogrel during pregnancy and the potential hazard to maternal and fetal health."4.90Successful gestation and delivery using clopidogrel for secondary stroke prophylaxis: a case report and literature review. ( Cuesta-Fernandez, A; Kayaleh, OR; Reilly, CR, 2014)
"Given the high risk of stroke after TIA (transient ischemia attack) or stroke and the adverse reaction of bleeding of antiplatelets, we undertook a meta-analysis, reviewed randomized controlled trials (RCTs) comparing aspirin plus clopidogrel with aspirin alone to determine the efficacy and adverse reaction of bleeding of the two protocols in the prevention of stroke."4.89The efficacy and adverse reaction of bleeding of clopidogrel plus aspirin as compared to aspirin alone after stroke or TIA: a systematic review. ( Hu, B; Huang, Y; Li, JY; Li, M; Mao, L; Xia, YP, 2013)
"Recurrent stroke risk did not differ between patients receiving dual-antiplatelet therapy and those receiving aspirin monotherapy (relative risk [RR], 0."4.89Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis. ( Hong, KS; Lee, M; Ovbiagele, B; Rao, NM; Saver, JL; Wu, YL, 2013)
"Low dose aspirin is effective in secondary stroke prevention."4.84Prevention of secondary stroke and transient ischaemic attack with antiplatelet therapy: the role of the primary care physician [corrected]. ( Kirshner, HS, 2007)
"The long-awaited results of the Management of Atherothrombosis with Clopidogrel in High-Risk Patients with Recent Transient Ischemic Attack (MATCH) study, a large-scale trial undertaken to evaluate the safety and efficacy of clopidogrel + aspirin for secondary prevention of stroke, have been published."4.83MATCH results: implications for the internist. ( Lutsep, HL, 2006)
"Using the key terms acute coronary syndrome, atherothrombosis, ischemic stroke, myocardial infarction, MI, peripheral arterial disease, TIA, transient ischemic attack, unstable angina,aspirin,ticlopidine,dipyridamole, and clopidogrel, we searched the MEDLINE database as well as the trial register of the Cochrane Groups to identify studies published from 1960 to August 2004."4.82Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease. ( Anand, SS; Tran, H, 2004)
" In the CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events) Trial, clopidogrel (clopidogrel bisulphate) was superior to acetylsalicylic acid (ASA) in reducing the combined risk of ischaemic stroke (IS), myocardial infarction (MI) or vascular death in patients with symptomatic atherosclerosis."4.81From CURE to MATCH: ADP receptor antagonists as the treatment of choice for high-risk atherothrombotic patients. ( Hacke, W, 2002)
"Aspirin is the treatment of first choice for long-term secondary prevention of vascular events in patients with confirmed non-cardioembolic ischaemic stroke or TIA."4.80Prevention of ischaemic stroke--antiplatelets. ( Brown, MM; McCabe, DJ, 2000)
"English-language articles published after 1977 and indexed in MEDLINE under the following Medical Subject Heading terms: anticoagulants, aspirin, dipyridamole, ticlopidine, or sulfinpyrazone, combined with cerebrovascular disorders."4.79Medical treatment for stroke prevention. ( Barnett, HJ; Feussner, JR; Matchar, DB; McCrory, DC, 1994)
"The CHANCE-2 study compared 3 weeks of aspirin-ticagrelor to aspirin-clopidogrel in CYP2C19 loss-of-function (LOF) allele carriers following a transient ischemic attack (TIA)/minor stroke and demonstrated a modestly lower risk of stroke recurrence with aspirin-ticagrelor."4.31Cost-effectiveness of testing for CYP2C19 loss-of-function carriers following transient ischemic attack/minor stroke: A Canadian perspective. ( Demchuk, AM; Jahn, B; Menon, BK; Micieli, A; Siebert, U; Singh, N, 2023)
"Bleeding is the most common adverse reaction to aspirin and can lead to drug discontinuation or even be life-threatening in the secondary prevention of stroke or transient ischemic attack."4.12Effect of body weight on bleeding events of aspirin in ischemic stroke or transient ischemic attack patients. ( Cheng, J; Deng, X; Li, H; Ma, Y; Shi, T; Wang, X; Wu, Y; Zhang, Z; Zhu, Q, 2022)
"We pooled individual patient data from 6 randomized clinical trials (CAPRIE [Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events], ESPS-2 [European Stroke Prevention Study-2], MATCH [Management of Atherothrombosis With Clopidogrel in High-Risk Patients], CHARISMA [Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance], ESPRIT [European/Australasian Stroke Prevention in Reversible Ischemia Trial], and PRoFESS [Prevention Regimen for Effectively Avoiding Second Strokes]) investigating antiplatelet therapy in the subacute or chronic phase after noncardioembolic transient ischemic attack or stroke."4.02Balancing Benefits and Risks of Long-Term Antiplatelet Therapy in Noncardioembolic Transient Ischemic Attack or Stroke. ( Algra, A; Bath, PM; Csiba, L; Diener, HC; Greving, JP; Hacke, W; Hilkens, NA; Kappelle, LJ; Koudstaal, PJ; Leys, D; Mas, JL; Sacco, RL, 2021)
"The relationship of CYP2C19 genotype and clinical efficacy in stroke or transient ischemic attack (TIA) patients treated with clopidogrel monotherapy or clopidogrel plus aspirin remains unknown."3.88Efficacy and safety of CYP2C19 genotype in stroke or transient ischemic attack patients treated with clopidogrel monotherapy or clopidogrel plus aspirin: Protocol for a systemic review and meta-analysis. ( Cui, M; Gu, ZC; Li, WY; Pan, MM; Yao, JC, 2018)
"Clopidogrel HTPR does not seem to be a major contributor to recurrent ischemic events in Danish ischemic stroke patients."3.88Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response. ( Jørgensen, NR; Rath, CL; Wienecke, T, 2018)
"From January 2014 to September 2014, a single center continuously enrolled patients with minor ischemic stroke or high-risk TIA and gave them antiplatelet therapy consisting of aspirin with clopidogrel."3.85The association between high on-treatment platelet reactivity and early recurrence of ischemic events after minor stroke or TIA. ( Cao, Y; Dong, K; Liu, L; Rao, Z; Wang, A; Wang, F; Wang, Y; Zhao, X; Zheng, H, 2017)
"Among patients in the CHAMPION trials with a prior cerebrovascular event at least 1 year before the percutaneous coronary intervention, the efficacy and bleeding profile of cangrelor compared with clopidogrel was similar to that in the overall trial."3.85Impact of Cerebrovascular Events Older Than One Year on Ischemic and Bleeding Outcomes With Cangrelor in Percutaneous Coronary Intervention. ( Bhatt, DL; Deliargyris, EN; Gibson, CM; Hamm, CW; Harrington, RA; Mahaffey, KW; Prats, J; Price, MJ; Sawlani, NN; Steg, PG; Stone, GW; White, HD, 2017)
"Aspirin and clopidogrel are both acceptable antiplatelet options for the secondary prevention of noncardioembolic ischemic stroke."3.85Antiplatelet Strategies and Outcomes in Patients with Noncardioembolic Ischemic Stroke from a Real-World Study with a Five-Year Follow-Up. ( Dai, H; He, P; Li, W; Lin, H; Ping, Y; Xu, H, 2017)
"The objective of this study was to compare nonresponders (NR) and responders (R) to clopidogrel with respect to presence of microvascular and macrovascular pathology in a cohort of patients with recent minor ischemic stroke (IS) or transient ischemic attack (TIA)."3.81Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease. ( Gigante, B; Höeg Dembrower, K; Jörneskog, G; Laska, AC; Laurencikas, E; Lundström, A; von Arbin, M; Wallén, H, 2015)
"The relation between high on-treatment platelet reactivity (HPR), and the level of glucose intolerance and insulin resistance (IR) was studied in clopidogrel-treated patients with minor ischemic stroke or TIA."3.80Glucose intolerance and insulin resistance as predictors of low platelet response to clopidogrel in patients with minor ischemic stroke or TIA. ( Jörneskog, G; Laska, AC; Lundström, A; Von Arbin, M; Wallén, H, 2014)
"A retrospective review of all patients with stroke and transient ischemic attack (TIA) tested for the clopidogrel CYP2C19 genotype was performed, with a collection of data including race/ethnicity, CYP2C19 status, and the presence of recurrent vascular events."3.80Reduced clopidogrel metabolism in a multiethnic population: prevalence and rates of recurrent cerebrovascular events. ( Barazangi, N; Chen, C; Jaramillo, V; Rose, J; Spokoyny, I; Tong, D; Wong, C, 2014)
"Japanese guidelines recommend aspirin 160-300 mg/day, starting within 48 h, for patients with acute cerebral infarction."3.80Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. ( Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T, 2014)
" Platelet reactivity was assessed in 18 patients with ischemic stroke/transient ischemic attack (TIA) 7 days (D7) and 90 days (D90) after prescription of clopidogrel, using four methods: light transmission aggregometry with 5 μmol/l ADP (LTA-ADP), vasodilator-stimulated phosphoprotein (VASP), Verify Now P2Y12 and platelet function analyzer (PFA) P2Y."3.80High on-treatment platelet reactivity in patients with ischemic cerebrovascular disease: assessment of prevalence and stability over time using four platelet function tests. ( Arroyo, AB; Bernal, A; Guiú, IS; Iniesta, JA; Jover, E; Lozano, ML; Martínez, C; Rivera, J; Rodríguez, JM; Vicente, V, 2014)
"Treatment with the combination of clopidogrel and aspirin taken soon after a transient ischemic attack (TIA) or minor stroke was shown to reduce the 90-day risk of stroke in a large trial in China, but the cost-effectiveness is unknown."3.80Cost-effectiveness of clopidogrel-aspirin versus aspirin alone for acute transient ischemic attack and minor stroke. ( Johnston, SC; Liu, G; Liu, L; Meng, X; Pan, Y; Wang, A; Wang, C; Wang, Y; Zhao, K; Zhao, X, 2014)
"In patients with ischemic stroke or transient ischemic attack, 43% (n=128) and 35% (n=54) were nonresponders to aspirin and clopidogrel, respectively."3.78Clinical outcomes using a platelet function-guided approach for secondary prevention in patients with ischemic stroke or transient ischemic attack. ( Bakdash, S; Bhatt, DL; Depta, JP; Fowler, J; Katzan, I; Kottke-Marchant, K; Novak, E, 2012)
"To examine healthcare costs among patients hospitalized for transient ischemic attack or ischemic stroke (TIA/stroke) and prescribed aspirin plus extended-release dipyridamole (ASA-ERDP) or clopidogrel (CLOPID) within 30 days post-discharge using a retrospective claims database from a large US managed care organization."3.78One-year follow-up healthcare costs of patients hospitalized for transient ischemic attack or ischemic stroke and discharged with aspirin plus extended-release dipyridamole or clopidogrel. ( Burton, TM; Lacey, M; Lang, K; Liu, F; Monsalvo, ML; Sander, S; Yu, Y, 2012)
" In this study, the authors assess the incidence of stroke or transient ischemic attack (TIA) following discontinuation of a 6-week course of clopidogrel in patients with cerebral aneurysms treated with stent-assisted techniques."3.78Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques. ( Abel, TJ; Chalouhi, N; Hasan, DM; Jabbour, PM; Kung, DK; Rossen, JD; Thomas, J; Wassef, SN, 2012)
"Patients who have had a recent transient ischemic attack (TIA) are at high risk for subsequent stroke."3.77Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly. ( Adams, HP; Gordon, DL, 1991)
"Aspirin plus clopidogrel (A+C) may be more effective than aspirin only (AO) acutely after TIA and minor stroke, but the risk of bleeding in the acute phase is uncertain."3.76Preliminary evidence of a high risk of bleeding on aspirin plus clopidogrel in aspirin-naïve patients in the acute phase after TIA or minor ischaemic stroke. ( Buchan, AM; Chandratheva, A; Geraghty, OC; Kennedy, J; Marquardt, L; Rothwell, PM, 2010)
"The combination of aspirin and clopidogrel is indicated after acute coronary events and possibly for a short period after TIA or minor ischemic stroke."3.76Low risk of rebound events after a short course of clopidogrel in acute TIA or minor stroke. ( Chandratheva, A; Geraghty, OC; Paul, NL; Rothwell, PM, 2010)
"(1) For patients with acute coronary syndromes who have undergone percutaneous angioplasty and stenting, the best-assessed treatment for preventing relapses is a combination of aspirin and clopidogrel; (2) Prasugrel, an antiplatelet drug belonging the same chemical class as clopidogrel, is authorized in the EU for use in this indication; (3) Clinical evaluation is based on a randomized double-blind trial comparing prasugrel + aspirin versus clopidogrel + aspirin in 13 608 patients with acute coronary syndromes, half of whom were treated for at least 15 months."3.75Prasugrel: new drug. After angioplasty and stenting: continue to use aspirin + clopidogrel. ( , 2009)
"In acute ischemic stroke and transient ischemic attack (TIA), aspirin is recommended to all patients (except immediately following thrombolysis)."3.74[Antithrombotic therapy in ischemic stroke and transient ischemic attack]. ( Husted, SE; Overgaard, K; Poulsen, TS, 2007)
"Clopidogrel and dipyridamole-aspirin are used frequently after stroke or transient ischemic attack."3.74Trends in usage of alternative antiplatelet therapy after stroke and transient ischemic attack. ( Hills, NK; Johnston, SC, 2008)
"The rapid and significant decline of MES in our stroke and TIA patients suggests the possible efficacy of dual antiplatelet therapy with aspirin and clopidogrel in patients with MES and symptomatic large-artery occlusive disease."3.73Efficacy of dual antiplatelet therapy in cerebrovascular disease as demonstrated by a decline in microembolic signals. A report of eight cases. ( Chang, HM; Chen, CL; Esagunde, RU; Gan, HY; Lee, MP; Wong, KS; Wong, MC, 2006)
" The patient evolved with neutropenia induced by ticlopidine after 10 days of treatment."3.71Fibroelastoma of the mitral valve as a cause of transient ischemic stroke. ( Alessi, A; Bertolin Précoma, D; Fontoura, D; Gomes de Carvalho, R; Oliveira, LR; Zanis Neto, J; Zapparoli, M, 2001)
"Within a cross-sectional study, nested in a cohort we identified 931 patients with a recent ischemic stroke or TIA who were discharged with OAC or with one of the antiplatelet medications aspirin, clopidogrel, or the combination of aspirin and extended-release dipyridamole."3.71Current strategies of secondary prevention after a cerebrovascular event: the Vienna stroke registry. ( Lalouschek, W; Lang, W; Müllner, M, 2001)
"Compared with aspirin alone, use of the new antiplatelet regimens, including aspirin combined with dipyridamole and clopidogrel bisulfate, has been found to further reduce the risk of stroke and other vascular events in patients who have experienced stroke or transient ischemic attack."3.70Cost-effectiveness of new antiplatelet regimens used as secondary prevention of stroke or transient ischemic attack. ( Bounameaux, H; Gaspoz, JM; Sarasin, FP, 2000)
"To report a case of ticlopidine-induced neutropenia occurring 18 days after discontinuation of the drug."3.69Delayed neutropenia with ticlopidine. ( Farver, DK; Hansen, LA, 1994)
"The study aimed to investigate the impact of clopidogrel combined with proton pump inhibitors (PPI) pantoprazole treatment on the prognosis of patients with transient ischemic attack (TIA)."2.84Report: Impact of drug combination of clopidogrel and pantoprazole In the prognosis of patients with transient ischemic attack. ( Lu, M, 2017)
"The incidences of transient ischemic attack, stroke, or death at up to 30 days after CAS in the high-OTR patients were similar between groups 1 and 2 (P = ."2.79Antiplatelet effects of clopidogrel dose adjustment (75 mg/d vs 150 mg/d) after carotid stenting. ( Cayuela, A; González, A; Gonzalez-Marcos, JR; Mayol, A; Moniche, F; Montaner, J, 2014)
"In one patient a transient ischemic attack occurred."2.78High versus standard clopidogrel loading in patients undergoing carotid artery stenting prior to cardiac surgery to assess the number of microemboli detected with transcranial Doppler: results of the randomized IMPACT trial. ( Ackerstaff, RG; Breet, NJ; De Vries, JP; Deneer, VH; Elsenberg, EH; Hackeng, CM; Kelder, JC; Schonewille, WJ; Suttorp, MJ; Ten Berg, JM; Tromp, SC; Van Der Heyden, J; Van Neerven, D; Van Werkum, J; Vos, JA; Wolters, F, 2013)
"A cause other than paradoxical embolism was usually apparent in patients with recurrent neurologic events."2.77Closure or medical therapy for cryptogenic stroke with patent foramen ovale. ( Adams, H; Albers, GW; Felberg, R; Furlan, AJ; Herrmann, H; Kar, S; Landzberg, M; Massaro, J; Mauri, L; Raizner, A; Reisman, M; Wechsler, L, 2012)
" The number of patients with adverse events and bleeding complications, and their severity, were significantly greater in the triple therapy group (p<0."2.73A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility. ( Bath, PM; England, T; Gray, LJ; Sare, GM; Sprigg, N; Willmot, MR; Zhao, L, 2008)
"In these patients with type 2 diabetes and a history of TIA, patterns of platelet inhibition differed significantly according to whether treatment was with ER-DP+ASA or clopidogrel with or without ASA."2.73Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b ( Hanley, DF; Malinin, AI; Pokov, AN; Serebruany, VL, 2008)
"The subjects were 75 patients with cerebral ischemia and 26 control subjects."2.67Shear-induced platelet aggregation in cerebral ischemia. ( Fukuyama, M; Handa, M; Ikeda, Y; Itagaki, I; Maruyama, S; Uchiyama, S; Yamazaki, M, 1994)
"Ticlopidine was more effective than aspirin in both sexes."2.66A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. Ticlopidine Aspirin Stroke Study Group. ( Adams, HP; Anderson, S; Easton, JD; Hass, WK; Kamm, B; Molony, BA; Pryse-Phillips, W, 1989)
" The combination of clopidogrel and aspirin is not recommended for long-term use (more than two to three years) because of increased bleeding risk."2.55Recurrent Ischemic Stroke: Strategies for Prevention. ( Garcellano, M; Oza, R; Rundell, K, 2017)
" Although administration of antiplatelet agents has been confirmed to be one of the major approaches for secondary prevention of noncardioembolic stroke, the short-term or long-term use of aspirin plus clopidogrel for secondary stroke prevention remains to be controversial."2.52Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention. ( Chen, W; Wang, Y, 2015)
"These events, previously called apoplexy, are now called strokes."2.50Stroke: transient ischemic attack. ( Silver, B; Wulf Silver, R, 2014)
"Bleeding is potentially the most significant antiplatelet-associated side effect."2.47Review and management of side effects associated with antiplatelet therapy for prevention of recurrent cerebrovascular events. ( Guthrie, R, 2011)
"Aspirin has been shown to reduce the risk of recurrent strokes, and the combination of aspirin and dipyridamole has repeatedly been shown to outperform aspirin alone."2.46Current guidelines on antiplatelet agents for secondary prevention of noncardiogenic stroke: an evidence-based review. ( Fung, K; Simmons, BB; Yeo, A, 2010)
"In the past, transient ischemic attack (TIA) was defined as any sudden, focal cerebral ischemic event with neurological deficit lasting <24 hours."2.46[New clinical concept and therapeutic strategy for TIA]. ( Urabe, T, 2010)
"Stroke is a leading cause of death and the primary cause of serious, long-term disability in the United States."2.44Combination antiplatelet agents for secondary prevention of ischemic stroke. ( Saseen, JJ; Vande Griend, JP, 2008)
"Patients who have transient ischemic attack (TIA) or ischemic stroke are at a high risk of having a first or recurrent stroke."2.44Antiplatelet agents and randomized trials. ( Diener, HC, 2007)
"The short-term risk of stroke after transient ischemic attack (TIA) is about 10% to 20% in the first 3 months, with much of the risk front-loaded in the first week."2.43Stroke prevention. MATCHing therapy to the patient with TIA. ( Buchan, AM; Demchuk, AM; Hill, MD; Weir, NU, 2005)
"Six years later after a left cerebral transient ischemic attack aspirin was replaced by ticlopidine."2.41[Cholestatic hepatitis as a rare side effect of therapy with ticlopidine]. ( Auer, J; Berent, R; Haidenthaler, A; Hinterholzer, G; Höbling, W; Knoflach, P, 2000)
"Ticlopidine is a new antiplatelet agent with a distinct mechanism of action."2.38Ticlopidine and antiplatelet therapy. ( Flores-Runk, P; Raasch, RH, 1993)
"Strokes due to carotid artery stenosis differ in outcome from those due to cardiac embolism; the most benign group is that of lacunar strokes."2.38Outcome of transient ischaemic attacks and stroke. ( Norris, JW, 1991)
"Ticlopidine is a new prototype antiplatelet drug chemically unrelated to currently available agents."2.38Ticlopidine: a new antiplatelet agent for cerebrovascular disease. ( Fagan, SC; Miller, AJ; Robert, S, 1991)
"Hemorrhagic stroke is not the only complication of thrombolysis, ischemic stroke can occur even if it is an extremely rare complication."1.46Ischemic stroke complicating thrombolytic therapy with tenecteplase for ST elevation myocardial infarction: two case reports. ( Arous, S; Bentaoune, T; El Ghali Benouna, M; Habbal, R; Haboub, M, 2017)
"All the patients presented with carotid artery stenosis >70% (North American Symptomatic Carotid Endarterectomy Trial [NASCET] criteria), which was symptomatic in 42 patients (transient ischemic attack, n = 32; minor stroke, n = 10) and asymptomatic in 146."1.46Dual Antiplatelet Therapy Does Not Increase the Risk of Bleeding After Carotid Endarterectomy: Results of a Prospective Study. ( Calio', FG; Illuminati, G; Masci, F; Pizzardi, G; Ricco, JB; Schneider, F, 2017)
"The early recurrence of neurological symptoms (NR) after urgent aggressive best medical therapy (BMT) in symptomatic carotid stenosis is not well documented."1.43Risk of early recurrent stroke in symptomatic carotid stenosis after best medical therapy and before endarterectomy. ( Ellemann, K; Gottschalksen, B; Owen-Falkenberg, A; Shahidi, S, 2016)
"Minor stroke and transient ischemic attack are common disorders with high rate of subsequent disabling stroke."1.43High-Sensitive C-Reactive Protein Predicts Recurrent Stroke and Poor Functional Outcome: Subanalysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events Trial. ( Li, J; Lin, J; Liu, L; Meng, X; Wang, A; Wang, C; Wang, Y; Zhao, X, 2016)
"Clinical question Following transient ischemic attack or acute minor stroke, does the combination of clopidogrel and aspirin reduce the risk of stroke greater than aspirin alone? Article chosen Wang Y, Wang Y, Zhao X, et al."1.42Clopidogrel with aspirin versus aspirin alone in prevention of stroke following transient ischemic attack or acute minor stroke. ( Lang, E; Seadon, S, 2015)
"Treatment of intracranial fusiform aneurysms is complex and controversial, and is associated with high morbidity and mortality rates."1.39Using Leo Plus stent as flow diverter and endoluminal remodeling in endovascular treatment of intracranial fusiform aneurysms. ( Ageitos, M; Arias-Rivas, S; Blanco, M; Castiñeira-Mourenza, JA; Masso, A; Pumar, JM; Rodríguez-Yáñez, M; Vazquez-Herrero, F, 2013)
"Of a total of 4905 (transient ischemic attack/ischemic stroke, and ocular events) patients, 115 symptomatic patients underwent CEA, 42% within 14 days of the index event and 99% within 14 days of surgical referral."1.39Urgent best medical therapy may obviate the need for urgent surgery in patients with symptomatic carotid stenosis. ( Ellemann, K; Hjerpsted, U; Owen-Falkenberg, A; Rai, A; Shahidi, S, 2013)
"Intracranial arterial stenosis (IAS) is thought to be responsible for 8% of all ischemic stroke subtypes."1.37The role of transcranial Doppler embolic monitoring in the management of intracranial arterial stenosis. ( Derksen, C; Khan, K; Saqqur, M; Sebastian, J, 2011)
"Ischemic stroke was reported in 57."1.35[Secondary prevention with clopidogrel or acetylsalicylic acid after acute cerebrovascular event. Health services research study of private primary care specialists]. ( Diehm, C; Köfüncü, E; Pittrow, D; Sander, D; Schwertfeger, M, 2008)
"We report a patient who presented with transient ischemic attack (TIA) associated with stenosis of the accessory MCA ostium."1.35Transient ischemic attack associated with stenosis of accessory middle cerebral artery: a case report. ( Gao, F; Jiang, WJ, 2009)
"Ticlopidine was then started."1.35Agenesis of the right internal carotid artery and Klippel-Feil syndrome: case report. ( Arpaia, G; Beretta, S; Braga, M; Canovaro, P; Crespi, V; Ferrarini, M; Pederzoli, M, 2009)
"Transient ischemic attack is one of the most common causes of transient neurologic deficit."1.35Severe anemia associated with transient ischemic attacks involving vertebrobasilar circulation. ( Chen, IC; Hsiao, CT; Hsiao, KY; Lin, LJ; Shiao, CJ, 2008)
"Patients with transient ischemic attack (TIA) or ischemic stroke carry a risk of recurrent stroke of between 5% and 20% per year."1.33Secondary stroke prevention with antiplatelet drugs: have we reached the ceiling? ( Diener, HC, 2006)
"To report procedure-related complications and neurological adverse events of unprotected over-the-wire (OTW) and protected rapid exchange (RX) carotid artery stenting (CAS) in a single-center patient series during an 8-year period."1.33Procedure-related complications and early neurological adverse events of unprotected and protected carotid stenting: temporal trends in a consecutive patient series. ( Ahmadi, A; Amighi, J; Boltuch, J; Dick, P; Minar, E; Mlekusch, W; Sabeti, S; Schillinger, M; Schlager, O, 2005)
"Patients suffering from a transient ischemic attack (TIA) or ischemic stroke are at high risk of a recurrent stroke."1.32[Secondary prevention of stroke with antiplatelet drugs]. ( Diener, HC, 2004)
"Unfortunately, VBA transient ischemic attacks (TIAs) herald a lethal or devastating event within 5 years in 25 to 30% of patients."1.31Stent-assisted angioplasty of intracranial vertebrobasilar atherosclerosis: an initial experience. ( Barr, JD; Furlan, AJ; Katzan, I; Krieger, D; Markarian, GZ; Masaryk, TJ; Perl, J; Rasmussen, PA; Sila, C, 2000)
"Ticlopidine treatment was stopped, and a prolonged course of prednisone was necessary to treat the pulmonary and intestinal symptoms."1.31Ticlopidine-induced interstitial pulmonary disease: a case report. ( Cornella, F; Kaeser, P; Persoz, CF; Rochat, T, 2001)
"Ticlopidine has been reported as causing neutropenia and isolated thrombocytopenia."1.29Thrombotic thrombocytopenic purpura associated with ticlopidine. ( Chin-Yee, IH; Kovacs, MJ; Soong, PY, 1993)
"A trial was performed on thirty-two patients with cerebrovascular disease (transient ischaemic attack and stroke) to assess the effect of ticlopidine, a new inhibitor of platelet aggregation, on some platelet functions and coagulation, and its safety in long-term use (6 months)."1.27Effects of long-term ticlopidine treatment on platelet function and its tolerability in cerebrovascular disease. ( Carfagna, S; Carrieri, P; Fioretti, A; Indaco, A; Orefice, G, 1984)
"A patient is described in whom transient ischemic attacks (TIA) had some features - namely the presence of headache and the progressive onset of symptoms - unusual for an embolic phenomenon but suggestive of a migrainous event."1.26[Migraine or transient ischemic attacks in a patient with essential thrombocythaemia. Treatment with ticlopidine (author's transl)]. ( Bousser, J; Bousser, MG; Conard, J; Lecrubier, C, 1980)

Research

Studies (256)

TimeframeStudies, this research(%)All Research%
pre-199010 (3.91)18.7374
1990's31 (12.11)18.2507
2000's78 (30.47)29.6817
2010's132 (51.56)24.3611
2020's5 (1.95)2.80

Authors

AuthorsStudies
Micieli, A1
Singh, N1
Jahn, B1
Siebert, U1
Menon, BK1
Demchuk, AM3
Wang, X3
Zhu, Q1
Wu, Y2
Li, H9
Deng, X1
Cheng, J1
Zhang, Z1
Ma, Y1
Shi, T1
McDermott, JH1
Leach, M1
Sen, D1
Smith, CJ1
Newman, WG1
Bath, PM4
Pan, YS1
Wang, YJ1
Cole, JW1
Hilkens, NA1
Algra, A2
Diener, HC14
Csiba, L2
Hacke, W3
Kappelle, LJ1
Koudstaal, PJ1
Leys, D3
Mas, JL3
Sacco, RL2
Greving, JP1
Wang, Y37
Lin, Y3
Meng, X12
Chen, W4
Chen, G1
Wang, Z3
Wu, J1
Wang, D10
Li, J5
Cao, Y3
Xu, Y2
Zhang, G1
Li, X2
Pan, Y10
Liu, L16
Zhao, X16
Rao, Z2
Zheng, H3
Wang, F2
Wang, A9
Dong, K2
Rodés-Cabau, J1
Masson, JB1
Welsh, RC1
Garcia Del Blanco, B1
Pelletier, M1
Webb, JG1
Al-Qoofi, F1
Généreux, P1
Maluenda, G1
Thoenes, M1
Paradis, JM1
Chamandi, C1
Serra, V1
Dumont, E1
Côté, M1
Arous, S1
Haboub, M1
El Ghali Benouna, M1
Bentaoune, T1
Habbal, R1
Lu, M1
Lee, M2
Saver, JL2
Hong, KS2
Rao, NM2
Wu, YL2
Ovbiagele, B2
Zhang, J2
Sun, H1
Ming, T1
Liu, X1
Cong, Y1
Li, F1
Li, Z2
Oza, R1
Rundell, K1
Garcellano, M1
Woodhouse, LJ1
Appleton, JP1
Beridze, M1
Christensen, H1
Dineen, RA1
Duley, L1
England, TJ1
Flaherty, K1
Havard, D1
Heptinstall, S1
James, M1
Krishnan, K1
Markus, HS4
Montgomery, AA1
Pocock, SJ1
Randall, M1
Ranta, A1
Robinson, TG1
Scutt, P1
Venables, GS1
Sprigg, N2
Johnston, SC19
Easton, JD7
Farrant, M2
Barsan, W2
Conwit, RA1
Elm, JJ1
Kim, AS2
Lindblad, AS1
Palesch, YY1
Ding, L1
Peng, B1
Yao, JC1
Cui, M1
Pan, MM1
Gu, ZC1
Li, WY1
Rath, CL1
Jørgensen, NR1
Wienecke, T1
Borchard-Tuch, C1
Lau, AY2
Zhao, Y2
Chen, C4
Leung, TW2
Fu, J2
Huang, Y2
Suwanwela, NC2
Han, Z2
Tan, KS2
Ratanakorn, D2
Wong, KS4
Lundström, A2
Laska, AC2
Von Arbin, M2
Jörneskog, G2
Wallén, H2
Pumar, JM1
Arias-Rivas, S1
Rodríguez-Yáñez, M1
Blanco, M1
Ageitos, M1
Vazquez-Herrero, F1
Castiñeira-Mourenza, JA1
Masso, A1
Kono, K1
Shintani, A1
Yoshimura, R1
Okada, H1
Tanaka, Y1
Fujimoto, T1
Tomura, N1
Terada, T1
Shahidi, S2
Owen-Falkenberg, A2
Hjerpsted, U1
Rai, A1
Ellemann, K2
Zuurbier, SM1
Vermeer, SE1
Hilkens, PH1
Roos, YB1
Rongen, GA1
Hankey, GJ5
Wang, C13
Cui, L1
Jia, J1
Dong, Q1
Xu, A1
Zeng, J1
Li, Y2
Xia, H1
Li, M3
Li, JY1
Xia, YP1
Mao, L1
Hu, B2
Spokoyny, I1
Barazangi, N1
Jaramillo, V1
Rose, J1
Wong, C1
Tong, D1
Battenhouse, H1
Conwit, R1
Dillon, C1
Elm, J1
Lindblad, A1
Morgenstern, L1
Poisson, SN1
Palesch, Y1
Weimar, C2
Gorelick, PB1
Farooq, MU1
Kakkos, SK1
Tsolakis, IA1
Sharma, M1
Khandelwal, P1
Jeong, YH1
Hill, MD4
Derdeyn, CP3
Chimowitz, MI3
Lynn, MJ3
Fiorella, D3
Turan, TN3
Janis, LS3
Montgomery, J2
Nizam, A1
Lane, BF3
Lutsep, HL4
Barnwell, SL2
Waters, MF3
Hoh, BL3
Hourihane, JM2
Levy, EI2
Alexandrov, AV2
Harrigan, MR2
Chiu, D2
Klucznik, RP2
Clark, JM2
McDougall, CG2
Johnson, MD2
Pride, GL2
Lynch, JR1
Zaidat, OO2
Rumboldt, Z2
Cloft, HJ2
Gouya, G1
Arrich, J1
Wolzt, M1
Huber, K1
Verheugt, FW2
Gurbel, PA2
Pirker-Kees, A1
Siller-Matula, JM1
Gremmel, T1
Koppensteiner, R1
Ay, C1
Panzer, S1
Takahashi, S1
Mizuno, O1
Sakaguchi, T1
Yamada, T1
Inuyama, L1
Nomani, F1
Kamal, AK2
Füessl, HS1
González, A1
Moniche, F1
Cayuela, A1
Gonzalez-Marcos, JR1
Mayol, A1
Montaner, J1
Jover, E1
Rodríguez, JM1
Bernal, A1
Arroyo, AB1
Iniesta, JA1
Guiú, IS1
Martínez, C1
Vicente, V1
Lozano, ML1
Rivera, J1
Tobin, WO4
Kinsella, JA4
Kavanagh, GF2
O'Donnell, JS2
McGrath, RT1
Coughlan, T4
Collins, DR3
O'Neill, D4
Egan, B3
Tierney, S3
Feeley, TM3
Murphy, RP4
McCabe, DJ5
Reilly, CR1
Cuesta-Fernandez, A1
Kayaleh, OR1
Silver, B1
Wulf Silver, R1
Liu, G1
Zhao, K1
He, F1
Xia, C1
Zhang, JH1
Li, XQ1
Zhou, ZH1
Li, FP1
Li, W2
Lv, Y1
Chen, HS1
Hu, Z1
Yang, L1
Zhang, Q2
Zheng, M1
Zhang, L1
Shang, X1
Yan, C1
Szapáry, L1
Koltai, K1
Tibold, A1
Fehér, A1
Harang, G1
Pusch, G1
Fehér, G1
Sandhu, RK1
Hohnloser, SH1
Pfeffer, MA1
Yuan, F1
Hart, RG1
Yusuf, S1
Connolly, SJ1
McAlister, FA1
Healey, JS1
Lin, J4
Jickling, GC1
Liu, F2
Tantry, US1
Seadon, S1
Lang, E1
Alderazi, YJ1
Batchelder, A1
Hunter, J1
Cairns, V1
Sandford, R1
Munshi, A1
Naylor, AR1
Xian, Y2
Fang, J1
Gigante, B1
Höeg Dembrower, K1
Laurencikas, E1
Leng, X1
Pu, Y1
Jing, J3
Zou, X1
Soo, Y1
Cotsonis, GA1
Davis, KA1
Miyares, MA1
Dietrich, E1
Xu, C1
Wang, P1
Xin, H1
Gong, Y1
McDonough, CW1
Royster, AJ1
Sheehan, TO1
Burkley, B1
Langaee, TY1
Mocco, J1
Zuckerman, SL1
Mummareddy, N1
Stephens, ML1
Ingram, C1
Shaffer, CM1
Denny, JC1
Brilliant, MH1
Kitchner, TE1
Linneman, JG1
Roden, DM1
Johnson, JA1
Gottschalksen, B1
Yang, C1
Qian, J1
Tang, X1
Gao, P1
Hu, Y1
Niu, PP1
Guo, ZN1
Jin, H1
Xing, YQ1
Yang, Y1
Yang, X1
Zhang, C1
Ge, F1
Lin, H2
Liu, Y1
Guo, R1
Ruan, Z1
Chang, T1
Xu, J1
Buck, J1
Kaboli, P1
Gage, BF1
Cram, P1
Vaughan Sarrazin, MS1
Amarenco, P1
Čulić, V1
Landman, GW1
Kleefstra, N1
Zhou, Y1
Yi, X1
Han, Y1
Yang, Q1
Huang, L1
Wang, G1
Sawlani, NN1
Harrington, RA1
Stone, GW1
Steg, PG1
Gibson, CM1
Hamm, CW1
Price, MJ1
Prats, J1
Deliargyris, EN1
Mahaffey, KW2
White, HD1
Bhatt, DL3
Xu, H1
Ping, Y1
He, P1
Dai, H1
Sun, X1
Tong, X1
Lo, WT1
Mo, D1
Gao, F2
Ma, N1
Wang, B1
Miao, Z1
Illuminati, G1
Schneider, F1
Pizzardi, G1
Masci, F1
Calio', FG1
Ricco, JB1
Moris, D1
Bakoyiannis, C1
Avgerinos, E1
Ou, L1
Serebruany, VL2
Alberts, MJ3
Hanley, DF2
Gray, LJ1
England, T1
Willmot, MR1
Zhao, L1
Sare, GM1
Sander, D1
Schwertfeger, M1
Köfüncü, E1
Diehm, C1
Pittrow, D1
Vande Griend, JP1
Saseen, JJ1
Yu, SC1
Lam, WW1
Chan, AY1
Wong, LK1
Jiang, WJ1
Biller, J1
Braga, M1
Pederzoli, M1
Beretta, S1
Ferrarini, M1
Canovaro, P1
Arpaia, G1
Crespi, V1
Gomez, CR1
Qureshi, AI1
Sebastian, J1
Derksen, C1
Khan, K1
Saqqur, M1
Albanese, A1
Esposito, G1
Puca, A1
Tuttolomondo, A1
Tirpakova, B1
Di Giuda, D1
Maira, G1
Di Lazzaro, V1
Simmons, BB1
Yeo, A1
Fung, K1
Geraghty, OC2
Kennedy, J2
Chandratheva, A2
Marquardt, L1
Buchan, AM3
Rothwell, PM3
Chang, HM2
Huang, YN1
Chollate, P1
Koh, A1
Hao, Q1
Kaste, M2
Polydorou, AD1
Megaloikonomos, P1
Moutiris, JA1
Polydorou, V1
Antypa, E1
Testembasi, E1
Tziakouri, CH1
Palatianos, G1
Nikas, D1
Bolos, K1
Polydorou, A1
Meves, SH1
Overbeck, U1
Kaiser, A1
Krogias, C1
Neubauer, H1
Paul, NL1
Feldman, MJ1
Curinga, G1
Milner, SM1
Fischer, D1
Haentjes, J1
Klein, G1
Schieffer, B1
Drexler, H1
Meyer, GP1
Schaefer, A1
Kral, M1
Herzig, R1
Sanak, D1
Skoloudik, D1
Vlachova, I1
Bartkova, A1
Hlustik, P1
Kovacik, M1
Kanovsky, P1
Brennan, D1
Mak, KH1
Fox, KA1
Topol, EJ1
Charles, J1
Miller, G1
Meyers, JL1
Davis, KL1
Yu, YF1
Weber, R1
Röther, J1
Guthrie, R1
Vidal-Jordana, A1
Barroeta-Espar, I1
Sáinz Pelayo, MP1
Mateo, J1
Delgado-Mederos, R1
Martí-Fàbregas, J1
Squizzato, A1
Romualdi, E1
Dentali, F1
Ageno, W1
Chaturvedi, S1
Bhattacharya, P1
Torbey, MT1
Urabe, T2
Rosenberg, K1
Aw, D1
Sharma, JC1
Khan, M1
Acelajado, MC1
Oparil, S1
Asil, T1
Ir, N1
Karaduman, F1
Cagli, B1
Tuncel, S1
Furlan, AJ2
Reisman, M1
Massaro, J1
Mauri, L1
Adams, H1
Albers, GW1
Felberg, R1
Herrmann, H1
Kar, S1
Landzberg, M1
Raizner, A1
Wechsler, L1
James, SK2
Storey, RF2
Khurmi, NS1
Husted, S2
Keltai, M1
Maya, J1
Morais, J2
Lopes, RD1
Nicolau, JC2
Pais, P1
Raev, D1
Lopez-Sendon, JL1
Stevens, SR1
Becker, RC1
Depta, JP1
Fowler, J1
Novak, E1
Katzan, I3
Bakdash, S1
Kottke-Marchant, K1
Burton, TM1
Lacey, M1
Yu, Y1
Monsalvo, ML1
Lang, K1
Sander, S1
Rossen, JD1
Chalouhi, N1
Wassef, SN1
Thomas, J1
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Jabbour, PM1
Kung, DK1
Hasan, DM1
Cox, D1
Collins, R1
McGrath, RA1
Biscaglia, S1
Tebaldi, M1
Vranckx, P1
Campo, G1
Valgimigli, M1
Van Der Heyden, J1
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Tromp, SC1
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Suttorp, MJ1
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Van Neerven, D1
Schonewille, WJ1
Wolters, F1
Ten Berg, JM1
Kohli, P1
Wallentin, L1
Reyes, E1
Horrow, J1
Angiolillo, DJ1
Ardissino, D1
Maurer, G1
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Cannon, CP1
Ito, E1
Takahashi, A1
Yamamoto, H1
Kuzuhara, S1
Uchiyama, S2
Nakajima, M1
Georgiadis, D1
Michel, P1
Bogousslavsky, J4
Baumgartner, RW1
Elkind, MS1
Brass, LM1
Cimminiello, C1
Matias-Guiu, J1
Rupprecht, HJ1
Nácul, FE1
de Moraes, E1
Penido, C1
Paiva, RB1
Méier-Neto, JG1
Moonis, M1
Fisher, M1
Moore, M1
Power, M1
Einecke, D1
Frey, JL1
Tran, H1
Anand, SS1
Weir, NU1
Eikelboom, JW1
Droste, DW1
Kaps, M1
Larrue, V1
Lees, KR1
Siebler, M2
Ringelstein, EB1
Biondi, A1
Katz, JM1
Vallabh, J1
Segal, AZ1
Gobin, YP1
Gebel, JM1
Fahey, CD1
Bernstein, RA1
Nitschmann, S1
Hartung, HP1
Boltuch, J1
Sabeti, S1
Amighi, J1
Dick, P1
Mlekusch, W1
Schlager, O1
Ahmadi, A1
Minar, E1
Schillinger, M1
Bezerra, DC1
Esagunde, RU1
Lee, MP1
Gan, HY1
Wong, MC1
Chen, CL1
Tulsyan, N1
Ouriel, K1
Kashyap, VS1
Calvet, D1
Touzé, E1
Wallaschofski, H1
Lohmann, T1
Hild, E1
Kobsar, A1
Siegemund, A1
Spilcke-Liss, E1
Hentschel, B1
Stumpf, C1
Daniel, WG1
Garlichs, CD1
Eigenthaler, M1
Cordonnier, C1
Gorelick, P2
Sechenova, O1
Hennekens, CH1
Sylaja, PN1
Liao, JK1
de Borst, GJ1
Hilgevoord, AA1
van der Mee, M1
Moll, FL1
van de Pavoordt, HD1
Macdonald, S1
Fintel, DJ1
Kirshner, HS1
Ryckborst, KJ1
Eliasziw, M1
Overgaard, K1
Poulsen, TS1
Husted, SE1
Weinberger, J1
Müller-Schunk, S1
Linn, J1
Peters, N1
Spannagl, M1
Deisenberg, M1
Brückmann, H1
Mayer, TE1
Gengo, FM1
Rainka, M1
Robson, M1
Gengo, MF1
Forrest, A1
Hourihane, M1
Bates, V1
Adams, RJ1
Albers, G1
Benavente, O1
Furie, K1
Goldstein, LB1
Halperin, J1
Harbaugh, R1
Kelly-Hayes, M1
Kenton, EJ1
Marks, M1
Schwamm, LH1
Hills, NK1
Malinin, AI1
Pokov, AN1
Hsiao, KY1
Hsiao, CT1
Lin, LJ1
Shiao, CJ1
Chen, IC1
Asensio Moreno, C1
Arias Jiménez, JL1
Aramburu Bodas, O1
Ortega Calvo, M1
Pérez Cano, R1
Nielsen, AA1
Veien, KT1
Jørgensen, LG1
Buck, TC1
Brandslund, I1
Christensen, C1
Skliut, M1
Jamieson, DG1
Boysen, G1
Ono, H1
Mizukami, M1
Kitamura, K1
Kikuchi, H1
Tohgi, H2
Gent, M1
Ellis, D1
Carrieri, P1
Orefice, G1
Fioretti, A1
Indaco, A1
Carfagna, S1
Bousser, MG1
Conard, J1
Lecrubier, C1
Bousser, J1
Farver, DK1
Hansen, LA1
Iwamoto, T1
Kubo, H1
Takasaki, M1
Matchar, DB1
McCrory, DC1
Barnett, HJ1
Feussner, JR1
Komiya, T1
Kudo, M1
Mizuno, Y1
Yamazaki, M1
Maruyama, S1
Handa, M1
Ikeda, Y1
Fukuyama, M1
Itagaki, I1
Weiller, C1
Brey, RL1
Oster, G1
Huse, DM1
Lacey, MJ1
Epstein, AM1
Macko, R1
Kovacs, MJ1
Soong, PY1
Chin-Yee, IH1
Flores-Runk, P1
Raasch, RH1
Nurhussein, MA1
Bellavance, A1
Rindone, JP1
Bryan, G1
Jimenez Moreno, FJ1
Junquera Florez, F1
Nuvias Casals, J1
Castells Fuste, L1
Gonzalez Fernandez, A1
Catella-Lawson, F1
FitzGerald, GA1
Chesney, CM1
Forbes, CD1
Pizzulli, L1
Lüderitz, B1
Brigot, C1
Courillon-Mallet, A1
Roucayrol, AM1
Cattan, D1
Leavey, SF1
Weinberg, J1
Rasmussen, PA1
Perl, J1
Barr, JD1
Markarian, GZ1
Sila, C1
Krieger, D1
Masaryk, TJ1
Sudlow, CL1
Dunbabin, DW1
Berent, R1
Hinterholzer, G1
Höbling, W1
Auer, J1
Haidenthaler, A1
Knoflach, P1
Sarasin, FP1
Gaspoz, JM1
Bounameaux, H1
Brown, MM1
Persoz, CF1
Cornella, F1
Kaeser, P1
Rochat, T1
Alessi, A1
Gomes de Carvalho, R1
Bertolin Précoma, D1
Fontoura, D1
Oliveira, LR1
Zanis Neto, J1
Zapparoli, M1
Lalouschek, W1
Lang, W1
Müllner, M1
Shukla, V1
Goertler, M1
Blaser, T1
Krueger, S1
Hofmann, K1
Baeumer, M1
Wallesch, CW1
Wilterdink, JL1
Norris, JW1
Adams, HP2
Gordon, DL1
Robert, S1
Miller, AJ1
Fagan, SC1
Warlow, C1
Janzon, L1
Bergqvist, D1
Boberg, J1
Boberg, M1
Eriksson, I1
Lindgärde, F1
Persson, G1
Almgren, B1
Fagher, B1
Kjellström, T1
Hass, WK1
Pryse-Phillips, W1
Molony, BA1
Anderson, S1
Kamm, B1
Mirsen, TR1
Hachinski, VC1
Fujita, K1
Yamashita, H1
Masumura, M1
Ehara, K1
Tamaki, N1
Matsumoto, S1
Harker, LA1
Murakami, M1

Clinical Trials (38)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Open-label, Active-Controlled and Blinded-Endpoint Trial Comparing the Antiplatelet Effects of Ticagrelor Plus Aspirin Versus Clopidogrel Plus Aspirin in Chinese Patients With High-risk Transient Ischemic Attack or Minor Stroke.[NCT02506140]Phase 2/Phase 3675 participants (Actual)Interventional2015-08-31Completed
Aspirin Versus Aspirin + ClopidogRel as Antithrombotic Treatment Following Transcatheter Aortic Valve Implantation With the Edwards Valve. A Randomized Study (the ARTE Trial)[NCT02640794]Phase 4222 participants (Actual)Interventional2015-01-31Completed
Aspirin Versus Aspirin + ClopidogRel as Antithrombotic Treatment Following Transcatheter Aortic Valve Implantation With the Edwards SAPIEN XT Valve. A Randomized Pilot Study (the ARTE Trial)[NCT01559298]Phase 4178 participants (Actual)Interventional2012-03-31Completed
Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial[NCT00991029]Phase 34,881 participants (Actual)Interventional2010-05-28Terminated (stopped due to The trial was halted by the DSMB.)
Trial of PCSK9 Inhibition in Patients With Acute Stroke and Symptomatic Intracranial Atherosclerosis - a Prospective, Randomized, Open-label, Blinded End-point Study With High-resolution MR Vessel Wall Imaging[NCT05001984]Phase 260 participants (Anticipated)Interventional2021-08-01Recruiting
Early Intensive Medical Therapy for the Prevention of Early Neurological Deterioration in Branch Atheromatous Disease[NCT04824911]Phase 2424 participants (Anticipated)Interventional2021-03-23Recruiting
Comparison of Clopidogrel-based Antiplatelet Therapy Versus Warfarin as Secondary Prevention Strategy for AntiPhospholipid Syndrome-related STROKE (APS-STROKE)[NCT05995600]Phase 4400 participants (Anticipated)Interventional2023-12-31Not yet recruiting
Genotype Guided Antiplatelet Therapy In Ischemic Stroke[NCT05763862]350 participants (Anticipated)Interventional2023-04-24Recruiting
A REAl-life Study on Short-term Dual Antiplatelet Treatment in Patients With Ischemic Stroke or Transient Ischemic Attack[NCT05476081]1,067 participants (Anticipated)Observational [Patient Registry]2021-02-03Recruiting
China Registry of Non-disabling Ischemic Cerebrovascular Events: A Prospective Multi-center, National Registry Trail[NCT03079674]10,000 participants (Anticipated)Observational [Patient Registry]2017-06-01Not yet recruiting
Antiplatelet Therapy in Acute Mild-Moderate Ischemic Stroke (ATAMIS): a Parallel Randomized, Open-label, Multicenter, Prospective Study[NCT02869009]Phase 33,000 participants (Actual)Interventional2016-11-30Completed
Randomized,Double-blind Trial Comparing the Effects of a 3-month Clopidogrel Regimen,Combined With ASA During the First 21days,Versus ASA Alone for the Acute Treatment of TIA or Minor Stroke[NCT00979589]Phase 35,100 participants (Actual)Interventional2009-12-31Completed
Efficacy of Drug-Eluting Vertebral Artery Stenting Treatment for Atherosclerotic Vertebral Arteries Stenosis in Real-World Clinical Observations: a Prospective, Multicenter, Open-access, Single-arm Clinical Study[NCT05644314]144 participants (Anticipated)Interventional2022-05-01Recruiting
Stenting vs. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis[NCT00576693]Phase 3451 participants (Actual)Interventional2008-10-31Completed
Stroke Imaging Package Study of Intracranial Atherosclerosis[NCT03719820]550 participants (Anticipated)Observational [Patient Registry]2018-11-14Recruiting
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging[NCT05907629]300 participants (Anticipated)Observational2023-12-30Not yet recruiting
Evolocumab Added to Statin Therapy in Patients With Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS)---a Pilot Study[NCT05741086]Phase 380 participants (Anticipated)Interventional2023-04-15Recruiting
China Angioplasty & Stenting for Symptomatic Intracranial Severe Stenosis (CASSISS): a New, Prospective, Multi-center, Randomized Controlled Trial in China[NCT01763320]Phase 3380 participants (Actual)Interventional2014-03-05Completed
Carotid Stenosis Management During COVID-19 Era - Best Medical Intervention Alone (CASCOM Pilot Study): A Prospective Observational Study[NCT04947046]120 participants (Anticipated)Observational2020-03-11Recruiting
A Multicenter Prospective observationaL Study to evAluate the effecT of Clopidogrel on the prEvention of Major vascuLar Events According to the gEnotype of Cytochrome P450 2C19 in Ischemic Stroke paTients; PLATELET Study[NCT04072705]2,927 participants (Actual)Observational2019-09-20Completed
Correlation Between Bleeding Complication and Treatment Failure on P2Y12 Inhibitors and Its Predictions Based on Cipherome's Pharmacogenomic Technology[NCT04580602]200 participants (Actual)Observational2020-10-07Completed
Antithrombotic Therapy After Left Atrial Appendage Occlusion: Double Antiplatelet Therapy vs Apixaban[NCT05632445]Phase 4160 participants (Actual)Interventional2019-05-01Completed
Intracranial Stenting in Non-acute Symptomatic Ischemic Stroke: an Open-label, Randomised Controlled Trial[NCT05063630]300 participants (Anticipated)Interventional2019-05-01Recruiting
Clinical Registration Trial of Intracranial Stenting for Patients With Symptomatic Intracranial Artery Stenosis:A Prospective Multi-center, Registry Trial[NCT01994161]840 participants (Anticipated)Observational [Patient Registry]2012-12-31Recruiting
Wingspan One Year Vascular Imaging Events and Neurologic Outcomes (WOVEN)[NCT04221984]129 participants (Actual)Observational [Patient Registry]2019-11-12Completed
Registry of Emergent Large veSsel oCclUsion duE to IntraCranial AtherosclerosiS[NCT05403593]600 participants (Anticipated)Observational [Patient Registry]2021-12-15Recruiting
Secondary Prevention of Small Subcortical Strokes (SPS3) Trial[NCT00059306]Phase 33,020 participants (Actual)Interventional2003-02-28Completed
A Prospective, Multi-center, Randomized Controlled Study to Evaluate the Safety and Efficacy of the Maurora® Sirolimus-Eluting Stent Versus the Apollo Stent in Intracranial Atherosclerotic Stenosis(Maurora ICAS Trial)[NCT05719883]156 participants (Anticipated)Interventional2023-02-20Recruiting
Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)[NCT00004732]2,502 participants (Actual)Interventional2000-12-31Completed
Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial: a Prospective, Randomized, Open-labelled, Blinded End-point Trial (DREAM-PRIDE)[NCT04948749]792 participants (Anticipated)Interventional2021-07-02Recruiting
The Effect of Early Administration of PCSK9 Inhibitor, Alirocumab to Acute Ischemic Stroke Patients Associated With Atherosclerosis on the Stroke Prognosis and Lipid Profile, a Single Center Study, Registry Based, Pragmatic, Prospective Trial[NCT06083961]Phase 4200 participants (Anticipated)Interventional2023-10-15Not yet recruiting
A Prospective, Multicenter, Randomized Controlled Trial to Evaluate the Safety and Efficacy of the STARFlex® Septal Closure System Versus Best Medical Therapy in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism [NCT00201461]Phase 2/Phase 3900 participants (Anticipated)Interventional2003-06-30Active, not recruiting
A Randomised, Double-blind, Parallel Group, Phase 3, Efficacy and Safety Study of Ticagrelor Compared With Clopidogrel for Prevention of Vascular Events in Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS) [PLATO- a Study of PLATelet Inh[NCT00391872]Phase 318,624 participants (Actual)Interventional2006-10-31Completed
Does the Magnitude of Platelet Inhibition Inversely Correlate With the Number of TCD-detected Microemboli in Asymptomatic Patients Undergoing Carotid Artery Stenting Prior to Cardiac Surgery Who Are Being Pre-treated With 300 mg or 600 mg Loading Dose of [NCT01146301]Phase 40 participants Interventional2008-03-31Completed
Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Phase II, Multicentre; Randomised, Dose-finding, Double-blind and Placebo Controlled Superiority Study With Parallel Groups[NCT01645306]Phase 2158 participants (Actual)Interventional2013-03-08Completed
Fast Assessment of Stroke and Transient Ischemic Attack to Prevent Early Recurrence (FASTER)[NCT00109382]Phase 2/Phase 3500 participants (Anticipated)Interventional2003-05-31Completed
Improvements of Hand Function in Chronic Stroke Related to Upper Arm Anesthesia[NCT00006414]12 participants Observational2000-10-31Completed
Induction of Mucosal Tolerance to E-Selectin for the Secondary Prevention of Stroke[NCT00012454]Phase 260 participants Interventional2001-03-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Composite of Ischemic Stroke, Myocardial Infarction, Death From Ischemic Vascular Causes, or Major Hemorrhage

Secondary efficacy outcome: Number of participants with ischemic stroke, myocardial infarction, death from ischemic vascular causes, or major hemorrhage (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel141
Placebo167

Composite of Ischemic Stroke, Myocardial Infarction, or Death From Ischemic Vascular Causes

Primary efficacy outcome: Number of Participants with Ischemic Stroke, Myocardial Infarction, or Death From Ischemic Vascular Causes (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel121
Placebo160

Death From Any Cause

Other safety outcome: Number of Participants with Death from any cause (NCT00991029)
Timeframe: up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel18
Placebo12

Death From Ischemic Vascular Causes

Secondary efficacy outcome: Number of participants with Death from ischemic vascular causes (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel6
Placebo4

Hemorrhagic Stroke

Other safety outcome: Number of participants with Hemorrhagic stroke (NCT00991029)
Timeframe: up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel5
Placebo3

Ischemic or Hemorrhagic Stroke

Secondary efficacy outcome: Number of participants with Ischemic or hemorrhagic stroke (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel116
Placebo156

Ischemic Stroke

Secondary efficacy outcome:Number of participants with Ischemic stroke (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel112
Placebo155

Major Hemorrhage

Primary safety outcome: Number of Participants with major hemorrhage (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel23
Placebo10

Major Hemorrhage Other Than Intracranial Hemorrhage

Other safety outcome: Number of Participants with Major hemorrhage other than intracranial hemorrhage (NCT00991029)
Timeframe: up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel17
Placebo7

Minor Hemorrhage

Other safety outcome:Number of Participants with Minor hemorrhage (NCT00991029)
Timeframe: up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel40
Placebo13

Myocardial Infarction

Secondary efficacy outcome: Number of participants with Myocardial infarction (NCT00991029)
Timeframe: Up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel10
Placebo7

Other Symptomatic Intracranial Hemorrhage

Other safety outcome: Number of participants with other symptomatic intracranial hemorrhage (NCT00991029)
Timeframe: up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel2
Placebo0

Symptomatic Intracerebral Hemorrhage

Other safety outcome: Number of participants with Symptomatic intracerebral hemorrhage (NCT00991029)
Timeframe: up to 90 days

InterventionParticipants (Count of Participants)
Clopidogrel2
Placebo2

Any Stroke or Death Within 30 Days of Enrollment or Any Revascularization Procedure OR an Ischemic Stroke in the Territory of the Symptomatic Intracranial Artery Beyond 30 Days After Enrollment.

Any stroke (ischemic, parenchymal brain hemorrhage, subarachnoid or intraventricular hemorrhage) or death within 30 days after enrollment OR any stroke (ischemic, parenchymal brain hemorrhage, subarachnoid or intraventricular hemorrhage) or death within 30 days of any revascularization procedure of the qualifying symptomatic intracranial artery done during follow-up, OR an ischemic stroke in the territory of the symptomatic intracranial artery from day 31 after study entry to completion of follow-up. (NCT00576693)
Timeframe: Mean length of follow-up was 2.4 years

Interventionparticipants (Number)
Intensive Medical Management Plus Stenting52
Intensive Medical Management Alone34

Any Periprocedural Stroke, Myocardial Infarction, or Death During a 30-day Peri-procedural Period, and Postprocedural Ipsilateral Stroke Thereafter, up to 4-years.

The primary aim of CREST is to assess if the efficacy of CAS differs from that of CEA in preventing stroke, myocardial infarction and death during a 30-day peri-procedural period, or ipsilateral stroke over the follow-up period in patients with symptomatic (>=50%) or asymptomatic (>=60%) extracranial carotid stenosis. Four-year follow-up, proportions reflecting the absolute efficacy of carotid-artery stenting (CAS) over that of carotid endarterectomy (CEA) were based on Kaplan-Meier survival estimates at the end of the 4 years. (NCT00004732)
Timeframe: 30 days and 4 years

InterventionPercentage (Mean)
Carotid-Artery Stenting7.2
Carotid Endarterectomy6.8

Differential Efficacy of CAS and CEA in Male and Female Participants in the Primary Endpoint (Any Periprocedural Stroke, Myocardial Infarction, or Death or Postprocedural Ipsilateral Stroke).

4-year follow-up, proportions reflecting the absolute efficacy of carotid-artery stenting (CAS) over that of carotid endarterectomy (CEA) were based on Kaplan-Meier survival estimates at the end of the 4 years. (NCT00004732)
Timeframe: 4 years

,
InterventionPercentage (Mean)
MenWomen
Carotid Endarterectomy6.86.7
Carotid-Artery Stenting6.28.9

Participants With Any Event From the Composite of All-cause Mortality, MI, and Stroke

Participants with death from any cause, MI, or stroke. If no event, censoring occurs at the earliest of patient withdrawal of consent or date of scheduled withdrawal from therapy. ITT analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR901
CLOPIDOGREL1065

Participants With Any Event From the Composite of Death From Vascular Causes, MI (Including Silent), Stroke, Recurrent Ischemia, Transient Ischemic Attack (TIA) and Other Arterial Thrombotic Events.

Participants with death from vascular causes, MI, stroke, recurrent ischemia, or other thrombotic events. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT analysis of whole population. Events were adjudicated. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR1290
CLOPIDOGREL1456

Participants With Any Event From the Composite of Death From Vascular Causes, MI, and Stroke for the Subgroup of Patients With Intent for Invasive Management at Randomization

Participants with death from vascular causes, MI, or stroke. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT analysis of intent for invasive management population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR569
CLOPIDOGREL668

Participants With Any Event From the Composite of Death From Vascular Causes, Myocardial Infarction (MI), and Stroke

Participants with death from vascular causes, MI, or stroke. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. Intention To Treat (ITT) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR864
CLOPIDOGREL1014

Participants With Any Major Bleeding Event

Participants with major (fatal/life-threatening or other) bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR961
CLOPIDOGREL929

Participants With Coronary Artery Bypass Graft (CABG) Major Bleeding

Participants with a major CABG-related bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. All CABG surgeries were submitted for adjudication by an endpoint committee as potential bleeds. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR619
CLOPIDOGREL654

Participants With Coronary Artery Bypass Graft (CABG) Major Fatal/Life-threatening Bleeding

Number of participants with a major fatal/life-threatening CABG-related bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. All CABG surgeries were submitted for adjudication by an endpoint committee as potential bleeds. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR329
CLOPIDOGREL341

Participants With Death From Any Cause

Participants with death from any cause. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR399
CLOPIDOGREL506

Participants With Death From Vascular Causes

Participants with death from vascular causes. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR353
CLOPIDOGREL442

Participants With Major or Minor Bleeding

Participants with major (fatal/life-threatening or other) or minor bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR1339
CLOPIDOGREL1215

Participants With MI Event

Participants with MI event. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR504
CLOPIDOGREL593

Participants With Non-CABG (Coronary Artery Bypass Graft) Related Major Bleeding

Participants with non CABG related major (fatal/life-threatening or other) bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR362
CLOPIDOGREL306

Participants With Non-procedural Major Bleeding

Participants with non-procedural major bleed by a study protocol scale based on need for treatment, number of transfusions, hemoglobin decrease, and other factors. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: First dosing up to 12 months

InterventionParticipants (Number)
TICAGRELOR235
CLOPIDOGREL180

Participants With Stroke

Participants with stroke. If no event, censoring occurs at the earliest of patient withdrawal consent or date of scheduled withdrawal from therapy. ITT (intention to treat) analysis of whole population. Events were adjudicated by an endpoint committee. (NCT00391872)
Timeframe: Randomization up to 12 months

InterventionParticipants (Number)
TICAGRELOR125
CLOPIDOGREL106

Participants With Ventricular Pauses of Greater Than or Equal to 3 Seconds in Patients Monitored by Holter 24 Hour ECG Recorders for 1 Week at 1 Month Following Randomization

Number of participants who were observed to have at least 1 ventricular pause of at least 3 seconds. Population is all patients who were observed over 2 week-long periods. Pauses were flagged algorithmically and confirmed by TIMI cardiologists. (NCT00391872)
Timeframe: 1-week period following randomization

InterventionParticipants (Number)
TICAGRELOR21
CLOPIDOGREL16

Participants With Ventricular Pauses of Greater Than or Equal to 3 Seconds in Patients Monitored by Holter 24-hour ECG Recorders for 1 Week Following Randomization

Number of participants who were observed to have at least 1 ventricular pause of at least 3 seconds. Population is all patients who were observed over 2 week-long periods. Pauses were flagged algorithmically and confirmed by Thrombolysis in Myocardial Infarction (TIMI) group cardiologists. (NCT00391872)
Timeframe: 1-week period following randomization

InterventionParticipants (Number)
TICAGRELOR84
CLOPIDOGREL51

Anti-Drug Antibodies

"Anti-drug antibodies were measured at baseline and 3 month after IMP application.~Number of patients with positive anti-drug antibodies compared to baseline are counted." (NCT01645306)
Timeframe: 3 month (+/- 1 month) after IMP application

InterventionParticipants (Count of Participants)
Placebo0
40 mg Revacept0
120 mg Revacept0

Any Clinical Event

patients with any stroke & TIA, myocardial infarction & percutaneous coronary intervention (PCI), death or bleeding within one year (365 days) after IMP application. (NCT01645306)
Timeframe: 365 days after IMP application

InterventionNumber of Events (Number)
Placebo19
40 mg Revacept15
120 mg Revacept10

Major Bleedings

patients with major bleedings occuring within 90 days after IMP application (NCT01645306)
Timeframe: 90 days after IMP application

InterventionParticipants (Count of Participants)
Placebo5
40 mg Revacept6
120 mg Revacept4

New DWI Lesion(s)

The number of new diffusion weighted imaging (DWI) lesion(s) reported. (1 day after intervention compared to baseline). (NCT01645306)
Timeframe: 1 day post intervention

InterventionNumber of new lesions (Mean)
Placebo1.2
40 mg Revacept1.0
120 mg Revacept0.6

Patients With Any Stroke or Transient Ischemic Attack (TIA)

patients with any stroke or TIA occuring within 90 days after IMP application. (NCT01645306)
Timeframe: 90 days after IMP application

InterventionParticipants (Count of Participants)
Placebo6
40 mg Revacept6
120 mg Revacept4

Participants With Adverse Events (AEs)

All adverse events were assessed during complete study period (~ 1 year after IMP application). (NCT01645306)
Timeframe: ~ 365 days after IMP application (whole study period)

,,
Interventionparticipants (Number)
patients with adverse eventspatients with drug related AEspatients with serious AEspatients with drug related serious AEspatients with AE with fatal outcome events
120 mg Revacept3221501
40 mg Revacept41101740
Placebo3541710

Reviews

65 reviews available for ticlopidine and Ischemic Attack, Transient

ArticleYear
The role of
    Expert review of clinical pharmacology, 2022, Volume: 15, Issue:7

    Topics: Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Humans; Ischemic Attack, Transient; Ischemic Stroke

2022
[Optimal antiplatelet strategy in patients with high-risk transient ischemic attack and minor ischemic stroke].
    Zhonghua nei ke za zhi, 2019, Sep-01, Volume: 58, Issue:9

    Topics: Brain Ischemia; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopi

2019
Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis.
    Stroke, 2017, Volume: 48, Issue:9

    Topics: Adenosine; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Plat

2017
Recurrent Ischemic Stroke: Strategies for Prevention.
    American family physician, 2017, Oct-01, Volume: 96, Issue:7

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; P

2017
Efficacy and safety of dual antiplatelet therapy in the elderly for stroke prevention: a systematic review and meta-analysis.
    European journal of neurology, 2018, Volume: 25, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Intracranial Hemorrhages;

2018
[Secondary prevention with clopidogrel after TIA or stroke].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:25

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; N

2013
The efficacy and adverse reaction of bleeding of clopidogrel plus aspirin as compared to aspirin alone after stroke or TIA: a systematic review.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Aspirin; Bleeding Time; Clopidogrel; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggreg

2013
Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis.
    Annals of internal medicine, 2013, Oct-01, Volume: 159, Issue:7

    Topics: Anticoagulants; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Human

2013
Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis.
    Stroke, 2014, Volume: 45, Issue:2

    Topics: Adenosine; Aged; Aspirin; Cerebral Hemorrhage; Cerebrovascular Disorders; Clopidogrel; Cohort Studie

2014
Successful gestation and delivery using clopidogrel for secondary stroke prophylaxis: a case report and literature review.
    Archives of gynecology and obstetrics, 2014, Volume: 290, Issue:3

    Topics: Adult; Clopidogrel; Delivery, Obstetric; Female; Humans; Infant, Newborn; Ischemic Attack, Transient

2014
Stroke: transient ischemic attack.
    FP essentials, 2014, Volume: 420

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Clopidogrel; Diffusion Magnetic Resonance I

2014
Aspirin plus clopidogrel as secondary prevention after stroke or transient ischemic attack: a systematic review and meta-analysis.
    Cerebrovascular diseases (Basel, Switzerland), 2015, Volume: 39, Issue:1

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Pla

2015
P2Y12 receptor inhibitors for secondary prevention of ischemic stroke.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:8

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggre

2015
Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention.
    Current cardiology reports, 2015, Volume: 17, Issue:10

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Gastrointestinal Hemorrhag

2015
Dual antiplatelet therapy with clopidogrel and aspirin after ischemic stroke: A review of the evidence.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Oct-01, Volume: 72, Issue:19

    Topics: Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic

2015
[Meta-analysis on the efficacy and adverse events of aspirin plus clopidogrel versus aspirin-monotherapy in patients with ischemic stroke or transient ischemic attack].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2015, Volume: 36, Issue:12

    Topics: Aspirin; Clopidogrel; Databases, Factual; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic At

2015
Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis.
    BMJ open, 2016, Mar-17, Volume: 6, Issue:3

    Topics: Aspirin; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hemorrhage; Humans; Ische

2016
Dual antiplatelet therapy after stroke or transient ischaemic attack - how long to treat? The duration of aspirin plus clopidogrel in stroke or transient ischaemic attack: a systematic review and meta-analysis.
    European journal of neurology, 2016, Volume: 23, Issue:6

    Topics: Aspirin; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrenc

2016
Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis.
    Circulation, 2017, Jan-03, Volume: 135, Issue:1

    Topics: Alleles; Clopidogrel; Cytochrome P-450 CYP2C19; Databases, Factual; Genotype; Humans; Ischemic Attac

2017
Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis.
    Circulation, 2017, Jan-03, Volume: 135, Issue:1

    Topics: Alleles; Clopidogrel; Cytochrome P-450 CYP2C19; Databases, Factual; Genotype; Humans; Ischemic Attac

2017
Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis.
    Circulation, 2017, Jan-03, Volume: 135, Issue:1

    Topics: Alleles; Clopidogrel; Cytochrome P-450 CYP2C19; Databases, Factual; Genotype; Humans; Ischemic Attac

2017
Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis.
    Circulation, 2017, Jan-03, Volume: 135, Issue:1

    Topics: Alleles; Clopidogrel; Cytochrome P-450 CYP2C19; Databases, Factual; Genotype; Humans; Ischemic Attac

2017
Combination antiplatelet agents for secondary prevention of ischemic stroke.
    Pharmacotherapy, 2008, Volume: 28, Issue:10

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combinat

2008
Antiplatelet therapy in ischemic stroke: variability in clinical trials and its impact on choosing the appropriate therapy.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Brain Ischemia; Clinical Trials as Topic;

2009
Current guidelines on antiplatelet agents for secondary prevention of noncardiogenic stroke: an evidence-based review.
    Postgraduate medicine, 2010, Volume: 122, Issue:2

    Topics: American Heart Association; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; I

2010
Oral antiplatelet therapy in stroke prevention. Minireview.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2010, Volume: 154, Issue:3

    Topics: Administration, Oral; Aspirin; Clopidogrel; Dipyridamole; Drug Combinations; Humans; Ischemic Attack

2010
Secondary prevention in the acute and early chronic phase after ischaemic stroke and transient ischaemic attacks with antiplatelet drugs--is antiplatelet monotherapy still reasonable?
    International journal of clinical practice, 2011, Volume: 65, Issue:5

    Topics: Abciximab; Acute Disease; Antibodies, Monoclonal; Aspirin; Chronic Disease; Clopidogrel; Delayed-Act

2011
Review and management of side effects associated with antiplatelet therapy for prevention of recurrent cerebrovascular events.
    Advances in therapy, 2011, Volume: 28, Issue:6

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Headache; Hemorrhage; Humans; Ischemi

2011
Antithrombotic management for transient ischemic attack and ischemic stroke (other than atrial fibrillation).
    Current atherosclerosis reports, 2011, Volume: 13, Issue:4

    Topics: Adenosine; Aryl Hydrocarbon Hydroxylases; Brain Ischemia; Cilostazol; Clinical Trials as Topic; Clop

2011
Statins for acute ischemic stroke.
    The Cochrane database of systematic reviews, 2011, Aug-10, Issue:8

    Topics: Atorvastatin; Cause of Death; Clopidogrel; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reduct

2011
New insights in antiplatelet therapy for patients with ischemic stroke.
    The neurologist, 2011, Volume: 17, Issue:5

    Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; I

2011
[New clinical concept and therapeutic strategy for TIA].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Diffusion Magnetic Resonance Imaging; Humans; Ischemic Attac

2010
Antiplatelets in secondary stroke prevention: should clopidogrel be the first choice?
    Postgraduate medical journal, 2012, Volume: 88, Issue:1035

    Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Ischemia; Ischemic Attack, Transient; Platelet Aggregati

2012
[Treatment of acute stroke -- an overview].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9

    Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Brain Edema; Case-Control Studies; Cereb

2003
The role of warfarin and aspirin in secondary prevention of stroke.
    Current cardiology reports, 2004, Volume: 6, Issue:2

    Topics: Anticoagulants; Aspirin; Clopidogrel; Heart Septal Defects, Atrial; Humans; Ischemic Attack, Transie

2004
Antiplatelet treatment for secondary prevention of acute ischemic stroke and transient ischemic attacks: mechanisms, choices and possible emerging patterns of use.
    Expert review of cardiovascular therapy, 2003, Volume: 1, Issue:4

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dipyridamole; Drug Combinations; Human

2003
The results of MATCH: light or heat?
    The Lancet. Neurology, 2004, Volume: 3, Issue:11

    Topics: Aspirin; Clopidogrel; Controlled Clinical Trials as Topic; Drug Therapy, Combination; Humans; Ischem

2004
Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease.
    JAMA, 2004, Oct-20, Volume: 292, Issue:15

    Topics: Administration, Oral; Angina Pectoris; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopido

2004
Stroke prevention. MATCHing therapy to the patient with TIA.
    Postgraduate medicine, 2005, Volume: 117, Issue:1

    Topics: Aspirin; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrenc

2005
Adding aspirin to clopidogrel after TIA and ischemic stroke: benefits do not match risks.
    Neurology, 2005, Apr-12, Volume: 64, Issue:7

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Drug Synergism; Drug Therapy, Combination; Humans; Ischemic At

2005
Emerging drugs in peripheral arterial disease.
    Expert opinion on emerging drugs, 2006, Volume: 11, Issue:1

    Topics: Administration, Oral; Anticoagulants; Arterial Occlusive Diseases; Arteries; Aspirin; Clopidogrel; D

2006
[Adding aspirin to clopidogrel in secondary prevention of ischemic stroke: no significant benefits. Results of the Match study].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:4 Pt 2

    Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Hemorrhage;

2006
MATCH results: implications for the internist.
    The American journal of medicine, 2006, Volume: 119, Issue:6

    Topics: Aspirin; Atherosclerosis; Clopidogrel; Controlled Clinical Trials as Topic; Double-Blind Method; Dru

2006
Evolving perspectives on clopidogrel in the treatment of ischemic stroke.
    Journal of cardiovascular pharmacology and therapeutics, 2006, Volume: 11, Issue:4

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggreg

2006
Current management of transient ischemic attack.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7, Issue:1

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Humans; Ischemic Attack, T

2007
Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?
    Circulation, 2007, Mar-27, Volume: 115, Issue:12

    Topics: Aspirin; Atherosclerosis; Cilostazol; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Dipyr

2007
[What should be done after the first TIA?].
    MMW Fortschritte der Medizin, 2007, May-21, Volume: 149 Suppl 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopi

2007
Antiplatelet therapy in cerebrovascular disease: implications of Management of Artherothrombosis with Clopidogrel in High-risk Patients and the Clopidogrel for High Artherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance studies' resu
    Clinical cardiology, 2007, Volume: 30, Issue:12

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Embolism, C

2007
Prevention of secondary stroke and transient ischaemic attack with antiplatelet therapy: the role of the primary care physician [corrected].
    International journal of clinical practice, 2007, Volume: 61, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Therapy, Combination; Family P

2007
Antiplatelet agents and randomized trials.
    Reviews in neurological diseases, 2007,Fall, Volume: 4, Issue:4

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; P

2007
Update on antiplatelet agents, including MATCH, CHARISMA, and ESPRIT.
    Current cardiology reports, 2008, Volume: 10, Issue:1

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Dipyridamole; Female; Humans; Ischemi

2008
Medical treatment for stroke prevention.
    Annals of internal medicine, 1994, Jul-01, Volume: 121, Issue:1

    Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocard

1994
[Ticlopidine. Secondary prevention of ischemic cerebral infarct].
    Der Internist, 1993, Volume: 34, Issue:12

    Topics: Adult; Aged; Cerebral Infarction; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female

1993
Ticlopidine and antiplatelet therapy.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:9

    Topics: Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Interactions; Hum

1993
Confusion in reperfusion. Problems in the clinical development of antithrombotic drugs.
    Circulation, 1997, Feb-18, Volume: 95, Issue:4

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Cerebrovascular Disorders; Drug Therapy, Combination; Fi

1997
Antiplatelet drugs in secondary prevention of stroke.
    International journal of clinical practice, 1998, Volume: 52, Issue:2

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Huma

1998
Thrombotic thrombocytopenic purpura associated with ticlopidine therapy.
    Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:4

    Topics: Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inh

1997
Thienopyridines or aspirin to prevent stroke and other serious vascular events in patients at high risk of vascular disease? A systematic review of the evidence from randomized trials.
    Stroke, 2000, Volume: 31, Issue:7

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhib

2000
[Cholestatic hepatitis as a rare side effect of therapy with ticlopidine].
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:7

    Topics: Aged; Atrial Fibrillation; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Cholestasis; Chro

2000
Prevention of ischaemic stroke--antiplatelets.
    British medical bulletin, 2000, Volume: 56, Issue:2

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Ischemic Attack, Transient; Pl

2000
Stroke prevention: antiplatelet and antithrombolytic therapy.
    Haemostasis, 2000, Volume: 30 Suppl 3

    Topics: Anticoagulants; Aspirin; Brain Damage, Chronic; Carotid Stenosis; Clinical Trials as Topic; Clopidog

2000
From CURE to MATCH: ADP receptor antagonists as the treatment of choice for high-risk atherothrombotic patients.
    Cerebrovascular diseases (Basel, Switzerland), 2002, Volume: 13 Suppl 1

    Topics: Angina, Unstable; Aspirin; Clopidogrel; Drug Therapy, Combination; Heparin; Humans; Intracranial Art

2002
Outcome of transient ischaemic attacks and stroke.
    Drugs, 1991, Volume: 42 Suppl 5

    Topics: Aged; Carotid Stenosis; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Middle Aged;

1991
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly.
    Clinics in geriatric medicine, 1991, Volume: 7, Issue:3

    Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Fem

1991
Ticlopidine: a new antiplatelet agent for cerebrovascular disease.
    Pharmacotherapy, 1991, Volume: 11, Issue:4

    Topics: Cerebrovascular Disorders; Clinical Trials as Topic; Drug Interactions; Female; Humans; Ischemic Att

1991
Ticlopidine, a new antithrombotic drug: but is it better than aspirin for longterm use?
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:3

    Topics: Aspirin; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocardial Infarction; Rando

1990
Transient ischemic attacks and stroke.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1988, Jun-15, Volume: 138, Issue:12

    Topics: Aspirin; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Risk Factors; Ticlopidine

1988
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986

Trials

55 trials available for ticlopidine and Ischemic Attack, Transient

ArticleYear
Effect of ticagrelor with clopidogrel on high on-treatment platelet reactivity in acute stroke or transient ischemic attack (PRINCE) trial: Rationale and design.
    International journal of stroke : official journal of the International Stroke Society, 2017, Volume: 12, Issue:3

    Topics: Adenosine; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Hetero

2017
Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomi
    JACC. Cardiovascular interventions, 2017, 07-10, Volume: 10, Issue:13

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Balloon Valvuloplasty; Canada; Clopidogrel; Drug The

2017
Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomi
    JACC. Cardiovascular interventions, 2017, 07-10, Volume: 10, Issue:13

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Balloon Valvuloplasty; Canada; Clopidogrel; Drug The

2017
Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomi
    JACC. Cardiovascular interventions, 2017, 07-10, Volume: 10, Issue:13

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Balloon Valvuloplasty; Canada; Clopidogrel; Drug The

2017
Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomi
    JACC. Cardiovascular interventions, 2017, 07-10, Volume: 10, Issue:13

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Balloon Valvuloplasty; Canada; Clopidogrel; Drug The

2017
Report: Impact of drug combination of clopidogrel and pantoprazole In the prognosis of patients with transient ischemic attack.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Chi-Square Distribution; China; Cl

2017
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.
    Lancet (London, England), 2018, 03-03, Volume: 391, Issue:10123

    Topics: Acute Disease; Aged; Aspirin; Brain Ischemia; Clopidogrel; Denmark; Dipyridamole; Drug Therapy, Comb

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female;

2018
Dual antiplatelets reduce microembolic signals in patients with transient ischemic attack and minor stroke: subgroup analysis of CLAIR study.
    International journal of stroke : official journal of the International Stroke Society, 2014, Volume: 9 Suppl A100

    Topics: Adult; Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; I

2014
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; F

2013
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.
    International journal of stroke : official journal of the International Stroke Society, 2013, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug The

2013
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
    Lancet (London, England), 2014, Jan-25, Volume: 383, Issue:9914

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-

2014
Antiplatelet effects of clopidogrel dose adjustment (75 mg/d vs 150 mg/d) after carotid stenting.
    Journal of vascular surgery, 2014, Volume: 60, Issue:2

    Topics: Aged; Angioplasty; Blood Platelets; Carotid Artery Diseases; Clopidogrel; Female; Humans; Ischemic A

2014
Clopidogrel plus aspirin versus aspirin alone for preventing early neurological deterioration in patients with acute ischemic stroke.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; M

2015
Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure.
    Stroke, 2015, Volume: 46, Issue:3

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopid

2015
Glycated albumin predicts the effect of dual and single antiplatelet therapy on recurrent stroke.
    Neurology, 2015, Mar-31, Volume: 84, Issue:13

    Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Glyc

2015
Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
    Circulation, 2015, Jul-07, Volume: 132, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studie

2015
Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
    Circulation, 2015, Jul-07, Volume: 132, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studie

2015
Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
    Circulation, 2015, Jul-07, Volume: 132, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studie

2015
Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
    Circulation, 2015, Jul-07, Volume: 132, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studie

2015
Effect of clopidogrel with aspirin on functional outcome in TIA or minor stroke: CHANCE substudy.
    Neurology, 2015, Aug-18, Volume: 85, Issue:7

    Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ischemic

2015
Dual antiplatelet therapy in stroke and ICAS: Subgroup analysis of CHANCE.
    Neurology, 2015, Sep-29, Volume: 85, Issue:13

    Topics: Aged; Aspirin; Clopidogrel; Constriction, Pathologic; Double-Blind Method; Drug Therapy, Combination

2015
Does the Stenting Versus Aggressive Medical Therapy Trial Support Stenting for Subgroups With Intracranial Stenosis?
    Stroke, 2015, Volume: 46, Issue:11

    Topics: Angioplasty; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Constriction, Patholo

2015
Combined clopidogrel-aspirin treatment for high risk TIA or minor stroke does not increase cerebral microbleeds.
    Neurological research, 2015, Volume: 37, Issue:11

    Topics: Aged; Aspirin; Cerebral Cortex; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Female;

2015
Treatment Effect of Clopidogrel Plus Aspirin Within 12 Hours of Acute Minor Stroke or Transient Ischemic Attack.
    Journal of the American Heart Association, 2016, Mar-21, Volume: 5, Issue:3

    Topics: Aged; Aspirin; Chi-Square Distribution; China; Clopidogrel; Disease Progression; Double-Blind Method

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
    JAMA, 2016, Jul-05, Volume: 316, Issue:1

    Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Co

2016
Effect of Estimated Glomerular Filtration Rate Decline on the Efficacy and Safety of Clopidogrel With Aspirin in Minor Stroke or Transient Ischemic Attack: CHANCE Substudy (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events).
    Stroke, 2016, Volume: 47, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Comorbidity; Drug Therapy, Combi

2016
Association of multiple infarctions and ICAS with outcomes of minor stroke and TIA.
    Neurology, 2017, Mar-14, Volume: 88, Issue:11

    Topics: Aged; Aspirin; Brain; Brain Infarction; Brain Ischemia; Clopidogrel; Female; Humans; Image Processin

2017
Impact of Glycemic Control on Efficacy of Clopidogrel in Transient Ischemic Attack or Minor Stroke Patients With
    Stroke, 2017, Volume: 48, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Double-Blind Method; Female; Glycated Serum Al

2017
Prasugrel in the poststroke cohort of the TRITON Trial: the clear and present danger.
    Cerebrovascular diseases (Basel, Switzerland), 2008, Volume: 26, Issue:1

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Doubl

2008
A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility.
    PloS one, 2008, Aug-06, Volume: 3, Issue:8

    Topics: Aged; Aspirin; Blood Pressure; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Drug Tolerance;

2008
Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:5

    Topics: Adult; Aged; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Drug Therapy, Combina

2010
Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Humans; Intention to Treat Ana

2010
Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Humans; Intention to Treat Ana

2010
Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Humans; Intention to Treat Ana

2010
Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Humans; Intention to Treat Ana

2010
Effect of clopidogrel plus ASA vs. ASA early after TIA and ischaemic stroke: a substudy of the CHARISMA trial.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:1

    Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Hu

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
    The New England journal of medicine, 2011, Sep-15, Volume: 365, Issue:11

    Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up St

2011
Closure or medical therapy for cryptogenic stroke with patent foramen ovale.
    The New England journal of medicine, 2012, Mar-15, Volume: 366, Issue:11

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Co

2012
Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack.
    Circulation, 2012, Jun-12, Volume: 125, Issue:23

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Brain Ischemia; Clopidogrel; Female; Humans; Intracranial

2012
High on-treatment platelet reactivity on commonly prescribed antiplatelet agents following transient ischaemic attack or ischaemic stroke: results from the Trinity Antiplatelet Responsiveness (TRAP) study.
    European journal of neurology, 2013, Volume: 20, Issue:2

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Cross-Over Studies; Female; Humans; Ischemic Attack, Tr

2013
High versus standard clopidogrel loading in patients undergoing carotid artery stenting prior to cardiac surgery to assess the number of microemboli detected with transcranial Doppler: results of the randomized IMPACT trial.
    The Journal of cardiovascular surgery, 2013, Volume: 54, Issue:3

    Topics: Aged; Cardiac Surgical Procedures; Carotid Stenosis; Clopidogrel; Dose-Response Relationship, Drug;

2013
Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the PLATO Study.
    Circulation, 2013, Feb-12, Volume: 127, Issue:6

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aged, 80 and over; Clopidogrel; Female; Humans; Ischemic A

2013
Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:9

    Topics: Adult; Aged; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ischemic Attac

2003
Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH): study design and baseline data.
    Cerebrovascular diseases (Basel, Switzerland), 2004, Volume: 17, Issue:2-3

    Topics: Arteriosclerosis; Aspirin; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inh

2004
Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Embolism;

2005
Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Embolism;

2005
Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Embolism;

2005
Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Embolism;

2005
Antiplatelets in stroke prevention: the MATCH trial. Some answers, many questions and countless perspectives.
    Cerebrovascular diseases (Basel, Switzerland), 2005, Volume: 20 Suppl 2

    Topics: Age Factors; Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Drug Therapy, Combination; Femal

2005
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2007, Volume: 34, Issue:2

    Topics: Aged; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dextrans; Dipyri

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Femal

2007
Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:3

    Topics: Age Factors; Aged; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel

2008
Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Biomarkers; Clopidogrel; Diabetes Mell

2008
Ticlopidine: quo vadis? Subarachnoid hemorrhage.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Clinical Trials as Topic; Double-Blind Method; Humans; Intracranial Aneurysm; Ischem

1984
The effect of ticlopidine on TIA compared with aspirin: a double-blind, twelve-month follow-up study.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; I

1984
Canadian American ticlopidine study (cats) in thromboembolic stroke.
    Agents and actions. Supplements, 1984, Volume: 15

    Topics: Anticoagulants; Clinical Trials as Topic; Follow-Up Studies; Humans; Intracranial Embolism and Throm

1984
Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease. Assessment by platelet aggregation testing.
    Stroke, 1994, Volume: 25, Issue:12

    Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Infarction; Collagen; Drug Monitoring; Female; Follow

1994
Shear-induced platelet aggregation in cerebral ischemia.
    Stroke, 1994, Volume: 25, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; beta-Thromboglobulin; Brain Ischemia; Cerebral Infarction;

1994
Efficacy of ticlopidine and aspirin for prevention of reversible cerebrovascular ischemic events. The Ticlopidine Aspirin Stroke Study.
    Stroke, 1993, Volume: 24, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cerebrovascular Disorders; Double-Blind Method; Female; Fol

1993
Cessation of embolic signals after antithrombotic prevention is related to reduced risk of recurrent arterioembolic transient ischaemic attack and stroke.
    Journal of neurology, neurosurgery, and psychiatry, 2002, Volume: 72, Issue:3

    Topics: Aged; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Intracranial Emb

2002
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly.
    Clinics in geriatric medicine, 1991, Volume: 7, Issue:3

    Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Fem

1991
Ticlopidine, a new antithrombotic drug: but is it better than aspirin for longterm use?
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:3

    Topics: Aspirin; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocardial Infarction; Rando

1990
Prevention of myocardial infarction and stroke in patients with intermittent claudication; effects of ticlopidine. Results from STIMS, the Swedish Ticlopidine Multicentre Study.
    Journal of internal medicine, 1990, Volume: 227, Issue:5

    Topics: Aged; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Intermittent Claudication; Ischem

1990
A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. Ticlopidine Aspirin Stroke Study Group.
    The New England journal of medicine, 1989, Aug-24, Volume: 321, Issue:8

    Topics: Aspirin; Cerebrovascular Disorders; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; M

1989
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986
[Pathophysiology and treatment of thrombosis. (2) The effect of ticlopidine on TIA compared with aspirin. A double-blind, 12-month and open 24-month follow-up study].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1987, Volume: 76, Issue:1

    Topics: Aspirin; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; Ischemic Attack,

1987

Other Studies

139 other studies available for ticlopidine and Ischemic Attack, Transient

ArticleYear
Cost-effectiveness of testing for CYP2C19 loss-of-function carriers following transient ischemic attack/minor stroke: A Canadian perspective.
    International journal of stroke : official journal of the International Stroke Society, 2023, Volume: 18, Issue:4

    Topics: Aspirin; Canada; Clopidogrel; Cost-Benefit Analysis; Cytochrome P-450 CYP2C19; Humans; Ischemic Atta

2023
Effect of body weight on bleeding events of aspirin in ischemic stroke or transient ischemic attack patients.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:10

    Topics: Aspirin; Body Weight; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, T

2022
    Neurology, 2021, 01-05, Volume: 96, Issue:1

    Topics: Clopidogrel; Humans; Ischemic Attack, Transient; Precision Medicine; Stroke; Ticlopidine

2021
Balancing Benefits and Risks of Long-Term Antiplatelet Therapy in Noncardioembolic Transient Ischemic Attack or Stroke.
    Stroke, 2021, Volume: 52, Issue:10

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Intracranial Hemorrhages; Isc

2021
The association between high on-treatment platelet reactivity and early recurrence of ischemic events after minor stroke or TIA.
    Neurological research, 2017, Volume: 39, Issue:8

    Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Ischem

2017
Ischemic stroke complicating thrombolytic therapy with tenecteplase for ST elevation myocardial infarction: two case reports.
    Journal of medical case reports, 2017, Jun-11, Volume: 11, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Electrocardiography; Fibrinolytic Agents; Heparin; Humans; Ischemic Atta

2017
High On-Treatment Platelet Reactivity to Adenosine Diphosphate Predicts Ischemic Events of Minor Stroke and Transient Ischemic Attack.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:10

    Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Platelets; Brain Ischemia; Clopidogrel; Drug Resi

2017
Association between platelet function and recurrent ischemic vascular events after TIA and minor stroke
.
    International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:10

    Topics: Alleles; Aspirin; Blood Coagulation Tests; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; F

2017
Efficacy and safety of CYP2C19 genotype in stroke or transient ischemic attack patients treated with clopidogrel monotherapy or clopidogrel plus aspirin: Protocol for a systemic review and meta-analysis.
    Medicine, 2018, Volume: 97, Issue:24

    Topics: Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Genotype; Humans; Ischemi

2018
Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:10

    Topics: Aged; Clopidogrel; Denmark; Drug Resistance; Female; Humans; Ischemic Attack, Transient; Male; Medic

2018
[In process].
    Medizinische Monatsschrift fur Pharmazeuten, 2017, Volume: 40, Issue:6

    Topics: Clopidogrel; Cytochrome P-450 CYP2C19; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhi

2017
New opportunities to optimize antithrombotic therapy for secondary stroke prevention.
    International journal of stroke : official journal of the International Stroke Society, 2019, Volume: 14, Issue:3

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Ischemic Attack, Trans

2019
Glucose intolerance and insulin resistance as predictors of low platelet response to clopidogrel in patients with minor ischemic stroke or TIA.
    Platelets, 2014, Volume: 25, Issue:2

    Topics: Aged; Blood Glucose; Blood Platelets; Clopidogrel; Female; Glucose Intolerance; Humans; Insulin Resi

2014
Using Leo Plus stent as flow diverter and endoluminal remodeling in endovascular treatment of intracranial fusiform aneurysms.
    Journal of neurointerventional surgery, 2013, Volume: 5 Suppl 3

    Topics: Adult; Aged; Anesthesia, General; Aneurysm; Angiography, Digital Subtraction; Aspirin; Blepharoptosi

2013
Triple antiplatelet therapy with addition of cilostazol to aspirin and clopidogrel for Y-stent-assisted coil embolization of cerebral aneurysms.
    Acta neurochirurgica, 2013, Volume: 155, Issue:8

    Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Embolization, Therapeutic;

2013
Urgent best medical therapy may obviate the need for urgent surgery in patients with symptomatic carotid stenosis.
    Stroke, 2013, Volume: 44, Issue:8

    Topics: Adult; Ambulatory Care; Carotid Stenosis; Clopidogrel; Disease Management; Drug Therapy, Combination

2013
[Clopidogrel plus acetylsalicylic acid: a deadly combination].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:25

    Topics: Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Preventi

2013
Dual antiplatelet therapy in acute transient ischemic attack and minor stroke.
    The New England journal of medicine, 2013, Jul-04, Volume: 369, Issue:1

    Topics: Clopidogrel; Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stro

2013
Early dual therapy for Chinese adults with TIA.
    BMJ (Clinical research ed.), 2013, Jul-03, Volume: 347

    Topics: Aspirin; China; Clopidogrel; Drug Therapy, Combination; Female; Humans; Intracranial Hemorrhages; Is

2013
Reduced clopidogrel metabolism in a multiethnic population: prevalence and rates of recurrent cerebrovascular events.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Cerebrovascular Disorders; Clopidogrel; Cytochrome P-450 CYP2C19; Dru

2014
Stroke: a new CHANCE for combination antiplatelet therapy?
    Nature reviews. Neurology, 2013, Volume: 9, Issue:10

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
Aspirin plus clopidogrel in acute minor ischaemic stroke or transient ischaemic attack is superior to aspirin alone for stroke risk reduction: CHANCE trial.
    Evidence-based medicine, 2014, Volume: 19, Issue:2

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2014
Clopidogrel with aspirin in minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, 10-03, Volume: 369, Issue:14

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
Clopidogrel with aspirin in minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, 10-03, Volume: 369, Issue:14

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
Clopidogrel with aspirin in minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, 10-03, Volume: 369, Issue:14

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
Clopidogrel with aspirin in minor stroke or transient ischemic attack.
    The New England journal of medicine, 2013, 10-03, Volume: 369, Issue:14

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
ACP Journal Club. Adding clopidogrel to aspirin after TIA or minor ischemic stroke reduced stroke without increasing bleeding.
    Annals of internal medicine, 2013, Oct-15, Volume: 159, Issue:8

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
Residual thrombin generation potential is inversely linked to the occurrence of atherothrombotic events in patients with peripheral arterial disease.
    European journal of clinical investigation, 2014, Volume: 44, Issue:3

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Blood Platelets; Cardiovascular Diseases; Clopidogrel

2014
Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan.
    Advances in therapy, 2014, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Dipyridamole

2014
LOAD: a pilot study of the safety of loading of aspirin & clopidogrel in acute ischaemic stroke and transient ischaemic attack. Is the loading dose of aspirin and clopidogrel a good alternative for patients with acute ischaemic stroke and TIA? How this wi
    JPMA. The Journal of the Pakistan Medical Association, 2013, Volume: 63, Issue:10

    Topics: Aspirin; Brain Ischemia; Female; Humans; Ischemic Attack, Transient; Male; Ticlopidine

2013
[Not Available].
    MMW Fortschritte der Medizin, 2013, Nov-07, Volume: 155, Issue:19

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2013
High on-treatment platelet reactivity in patients with ischemic cerebrovascular disease: assessment of prevalence and stability over time using four platelet function tests.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2014, Volume: 25, Issue:6

    Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Cell Adhesion Molecules; Cells, Cul

2014
Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
    Journal of neurology, 2014, Volume: 261, Issue:7

    Topics: Adult; Aged; Aspirin; Clopidogrel; Dipyridamole; Enzyme-Linked Immunosorbent Assay; Female; Humans;

2014
Cost-effectiveness of clopidogrel-aspirin versus aspirin alone for acute transient ischemic attack and minor stroke.
    Journal of the American Heart Association, 2014, Jun-05, Volume: 3, Issue:3

    Topics: Aspirin; China; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; H

2014
Does clopidogrel with aspirin after acute minor stroke or transient ischemic attack increase the risk of cerebral hemorrhage?
    Chinese medical journal, 2014, Volume: 127, Issue:18

    Topics: Aspirin; Cerebral Hemorrhage; Clopidogrel; Humans; Ischemic Attack, Transient; Male; Middle Aged; Ti

2014
[Clopidogrel resistance in cerebrovascular disease -- results of one-year follow-up].
    Orvosi hetilap, 2015, Jan-11, Volume: 156, Issue:2

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; C-Reactive Protein; Clopidogrel; Drug Resistance; Female

2015
Comment: TIA response to antiplatelets stratified by glycated albumin.
    Neurology, 2015, Mar-31, Volume: 84, Issue:13

    Topics: Aspirin; Clopidogrel; Female; Humans; Ischemic Attack, Transient; Male; Stroke; Ticlopidine

2015
Clopidogrel with aspirin versus aspirin alone in prevention of stroke following transient ischemic attack or acute minor stroke.
    CJEM, 2015, Volume: 17, Issue:3

    Topics: Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidi

2015
Dual antiplatelet therapy for TIA reduces subsequent disability: A CHANCE to improve outcomes?
    Neurology, 2015, Aug-18, Volume: 85, Issue:7

    Topics: Aspirin; Female; Humans; Ischemic Attack, Transient; Male; Outcome Assessment, Health Care; Platelet

2015
Dual Antiplatelet Therapy Prior to Expedited Carotid Surgery Reduces Recurrent Events Prior to Surgery without Significantly Increasing Peri-operative Bleeding Complications.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2015, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Stenosis; Clopidogrel; Drug A

2015
Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:10

    Topics: Aged; Blood Glucose; Carotid Artery Diseases; Cerebral Small Vessel Diseases; Clopidogrel; Cohort St

2015
CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.
    Journal of neurosurgery, 2016, Volume: 124, Issue:6

    Topics: Aged; Aspirin; Carboxylic Ester Hydrolases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Gene Freq

2016
Risk of early recurrent stroke in symptomatic carotid stenosis after best medical therapy and before endarterectomy.
    International journal of stroke : official journal of the International Stroke Society, 2016, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Carotid Arteries; Carotid Stenosis; Clopidogrel; Endarterectomy, C

2016
High-Sensitive C-Reactive Protein Predicts Recurrent Stroke and Poor Functional Outcome: Subanalysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events Trial.
    Stroke, 2016, Volume: 47, Issue:8

    Topics: Aged; Aspirin; C-Reactive Protein; Clopidogrel; Drug Therapy, Combination; Female; Humans; Incidence

2016
Trends in antithrombotic therapy for atrial fibrillation: Data from the Veterans Health Administration Health System.
    American heart journal, 2016, Volume: 179

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Atrial Fibrillation; Clopidogrel; Dabigatran

2016
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
    The New England journal of medicine, 2016, 10-06, Volume: 375, Issue:14

    Topics: Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibit

2016
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
    The New England journal of medicine, 2016, 10-06, Volume: 375, Issue:14

    Topics: Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibit

2016
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
    The New England journal of medicine, 2016, 10-06, Volume: 375, Issue:14

    Topics: Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibit

2016
Impact of Cerebrovascular Events Older Than One Year on Ischemic and Bleeding Outcomes With Cangrelor in Percutaneous Coronary Intervention.
    Circulation. Cardiovascular interventions, 2017, Volume: 10, Issue:1

    Topics: Adenosine Monophosphate; Aged; Brain Ischemia; Chi-Square Distribution; Clopidogrel; Coronary Artery

2017
Antiplatelet Strategies and Outcomes in Patients with Noncardioembolic Ischemic Stroke from a Real-World Study with a Five-Year Follow-Up.
    Translational stroke research, 2017, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; China; Clopidogrel; Drug Therapy, Combination; Female; Foll

2017
Risk Factors of Subacute Thrombosis After Intracranial Stenting for Symptomatic Intracranial Arterial Stenosis.
    Stroke, 2017, Volume: 48, Issue:3

    Topics: Adult; Aged; Aspirin; Clopidogrel; Constriction, Pathologic; Female; Humans; Ischemic Attack, Transi

2017
Dual Antiplatelet Therapy Does Not Increase the Risk of Bleeding After Carotid Endarterectomy: Results of a Prospective Study.
    Annals of vascular surgery, 2017, Volume: 40

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Asymptomatic Diseases; Carotid Stenosis; Clopidogr

2017
Letter by Moris et al Regarding Article, "Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)".
    Stroke, 2017, Volume: 48, Issue:4

    Topics: Adenosine; Aspirin; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Tic

2017
Response by Wang and Johnston to Letter Regarding Article, "Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcom
    Stroke, 2017, Volume: 48, Issue:4

    Topics: Adenosine; Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregat

2017
Secondary stroke prevention with antiplatelet drugs: have we reached the ceiling?
    International journal of stroke : official journal of the International Stroke Society, 2006, Volume: 1, Issue:1

    Topics: Age Factors; Aged; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combi

2006
[Secondary prevention with clopidogrel or acetylsalicylic acid after acute cerebrovascular event. Health services research study of private primary care specialists].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:36

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Comorbidity; Cross-Sectional Studies; Female;

2008
Would self-expanding stent occlude middle cerebral artery perforators?
    Stroke, 2009, Volume: 40, Issue:5

    Topics: Adult; Aged; Angioplasty; Aspirin; Clopidogrel; Female; Follow-Up Studies; Humans; Infarction, Middl

2009
Transient ischemic attack associated with stenosis of accessory middle cerebral artery: a case report.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:7

    Topics: Aphasia; Aspirin; Cerebral Angiography; Clopidogrel; Constriction, Pathologic; Humans; Hypertension;

2009
Agenesis of the right internal carotid artery and Klippel-Feil syndrome: case report.
    Spine, 2009, Sep-15, Volume: 34, Issue:20

    Topics: Abnormalities, Multiple; Brain; Carotid Artery, Internal; Female; Humans; Ischemic Attack, Transient

2009
Medical treatment of patients with intracranial atherosclerotic disease.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2009, Volume: 19 Suppl 1

    Topics: Anticoagulants; Aspirin; Atherosclerosis; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Emb

2009
Prasugrel: new drug. After angioplasty and stenting: continue to use aspirin + clopidogrel.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogr

2009
The role of transcranial Doppler embolic monitoring in the management of intracranial arterial stenosis.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2011, Volume: 21, Issue:2

    Topics: Angiography, Digital Subtraction; Aspirin; Atorvastatin; Blood Flow Velocity; Cerebral Angiography;

2011
Positional brain ischemia with MCA occlusion successfully treated with extra-intracranial bypass.
    Cerebrovascular diseases (Basel, Switzerland), 2010, Volume: 29, Issue:4

    Topics: Aspirin; Cerebral Revascularization; Clopidogrel; Humans; Infarction, Middle Cerebral Artery; Ischem

2010
Preliminary evidence of a high risk of bleeding on aspirin plus clopidogrel in aspirin-naïve patients in the acute phase after TIA or minor ischaemic stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2010, Volume: 29, Issue:5

    Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fol

2010
Time matters for reducing risk of stroke.
    The Lancet. Neurology, 2010, Volume: 9, Issue:5

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Risk; Stroke; T

2010
Carotid angioplasty in asymptomatic patients undergoing CABG surgery.
    International angiology : a journal of the International Union of Angiology, 2010, Volume: 29, Issue:3

    Topics: Aged; Angioplasty, Balloon; Anticoagulants; Carotid Stenosis; Clopidogrel; Coronary Angiography; Cor

2010
[Switching from clopidogrel hydrogen sulfate to clopidogrel besylate. Impaired antiplatelet effect in patients with ischemic stroke].
    Der Nervenarzt, 2010, Volume: 81, Issue:8

    Topics: Aged; Cerebral Infarction; Clopidogrel; Drug Resistance; Humans; Ischemic Attack, Transient; Male; N

2010
Low risk of rebound events after a short course of clopidogrel in acute TIA or minor stroke.
    Neurology, 2010, Jun-08, Volume: 74, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic A

2010
Clopidogrel and burns: platelet replacement therapy may not prevent postoperative bleeding.
    Burns : journal of the International Society for Burn Injuries, 2010, Volume: 36, Issue:7

    Topics: Aged; Burns; Clopidogrel; Epinephrine; Hemostatics; Humans; Ischemic Attack, Transient; Male; Platel

2010
Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism: procedural and follow-up results after implantation of the Amplatzer®-occluder device.
    Journal of interventional cardiology, 2011, Volume: 24, Issue:1

    Topics: Aspirin; Cardiac Catheterization; Clopidogrel; Echocardiography, Transesophageal; Embolism, Paradoxi

2011
TIAs - management in general practice.
    Australian family physician, 2010, Volume: 39, Issue:11

    Topics: Anticoagulants; Antihypertensive Agents; Aspirin; Atorvastatin; Clopidogrel; Dipyridamole; Dopamine

2010
Stroke and transient ischemic attack in the long-term care setting: patient characteristics, medication treatment, and length of stay.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2011, Volume: 26, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; Clopidogrel; Databases, Factual; Drug Administration Schedu

2011
[Intracerebral hemorrhage in anticoagulated patients: what do we do afterwards?].
    Neurologia (Barcelona, Spain), 2012, Volume: 27, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Cerebral Hemorrhage; Clopidogrel; Female; Follow-Up Studies; Humans;

2012
Medical management trumps stenting for intracranial arterial stenosis.
    The American journal of nursing, 2011, Volume: 111, Issue:12

    Topics: Angioplasty; Aspirin; Cerebral Arteries; Clopidogrel; Combined Modality Therapy; Constriction, Patho

2011
My patient just had a transient ischaemic attack. Can I predict his risk for stroke? Is stroke inevitable or preventable?
    JPMA. The Journal of the Pakistan Medical Association, 2011, Volume: 61, Issue:7

    Topics: Aspirin; Clopidogrel; Evidence-Based Medicine; Humans; Ischemic Attack, Transient; Middle Aged; Plat

2011
Antiplatelet therapy for transient ischemic attack.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Clopidogrel; Cognition Disorders;

2012
Combined antithrombotic treatment with aspirin and clopidogrel for patients with capsular warning syndrome: a case report.
    The neurologist, 2012, Volume: 18, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Internal Capsule; Intracranial Thrombosis; Ischemic Atta

2012
Beware of novel antiplatelet therapy in acute coronary syndrome patients with previous stroke.
    Circulation, 2012, Jun-12, Volume: 125, Issue:23

    Topics: Acute Coronary Syndrome; Adenosine; Clopidogrel; Female; Humans; Ischemic Attack, Transient; Male; S

2012
Clinical outcomes using a platelet function-guided approach for secondary prevention in patients with ischemic stroke or transient ischemic attack.
    Stroke, 2012, Volume: 43, Issue:9

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Fem

2012
One-year follow-up healthcare costs of patients hospitalized for transient ischemic attack or ischemic stroke and discharged with aspirin plus extended-release dipyridamole or clopidogrel.
    Journal of medical economics, 2012, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Clopidogrel; Delayed-Action Preparations; Drug Therap

2012
Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques.
    Journal of neurosurgery, 2012, Volume: 117, Issue:5

    Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Drug Therapy, Combina

2012
Prevalence of ex vivo high on-treatment platelet reactivity on antiplatelet therapy after transient ischemic attack or ischemic stroke on the PFA-100(®) and VerifyNow(®).
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2013, Volume: 22, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Aspirin, Dipyridamole Drug Combination; Blood Platelets; Br

2013
Longitudinal assessment of thrombin generation potential in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
    Journal of neurology, 2013, Volume: 260, Issue:2

    Topics: Adult; Aged; Aspirin; Clopidogrel; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Longitu

2013
Effects of pre-hospital clopidogrel administration on early and late residual platelet reactivity in ST-segment elevation myocardial infarction patients undergoing primary intervention.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:1

    Topics: Aged; Belgium; Blood Platelets; Clopidogrel; Coronary Thrombosis; Drug Administration Schedule; Emer

2013
Aspirin therapy should be first-line treatment in secondary prevention of stroke--against.
    Stroke, 2002, Volume: 33, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug

2002
[PRoFESS study presented. Change in secondary prevention].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Aspirin, Dipyridamole Drug Combination; Benzimida

2003
[Dual platelet inhibition with clopidogrel and ASS. Who profits from the combination?].
    MMW Fortschritte der Medizin, 2003, Jul-10, Volume: 145, Issue:27-28

    Topics: Acute Disease; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Cyclooxygenase Inhi

2003
Massive nasal bleeding and hemodynamic instability associated with clopidogrel.
    Pharmacy world & science : PWS, 2004, Volume: 26, Issue:1

    Topics: Clopidogrel; Deamino Arginine Vasopressin; Epistaxis; Female; Hemodynamics; Hemostatics; Humans; Isc

2004
Perioperative hemorrhage and combined clopidogrel and aspirin therapy.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Combinations; Endarterectomy, Carotid; Female; G

2004
[Secondary prevention of TIA and stroke. How much must thrombocytes not be inhibited?].
    MMW Fortschritte der Medizin, 2004, Jun-10, Volume: 146, Issue:24

    Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Hemo

2004
[For which patient ASS, clopidogrel or dipyridamole? (interview by Dr. Med. Dirk Einecke)].
    MMW Fortschritte der Medizin, 2004, Jun-10, Volume: 146, Issue:24

    Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Com

2004
[Clopidogrel protection is not increased further by ASS!].
    Praxis, 2004, Aug-25, Volume: 93, Issue:35

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ische

2004
[Secondary prevention of stroke with antiplatelet drugs].
    Medizinische Klinik (Munich, Germany : 1983), 2004, Aug-15, Volume: 99 Suppl 1

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack,

2004
Is clopidogrel the antiplatelet drug of choice for high-risk patients with stroke/TIA?: Yes.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:6

    Topics: Clinical Trials as Topic; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhi

2005
Is clopidogrel the antiplatelet drug of choice for high-risk patients with stroke/TIA?: No.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:6

    Topics: Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inh

2005
Progressive symptomatic carotid dissection treated with multiple stents.
    Stroke, 2005, Volume: 36, Issue:9

    Topics: Angiography; Angioplasty; Anticoagulants; Aspirin; Blood Vessel Prosthesis Implantation; Carotid Art

2005
Secondary stroke prevention with antiplatelet therapy with emphasis on the cardiac patient: a neurologist's view.
    Journal of the American College of Cardiology, 2005, Sep-06, Volume: 46, Issue:5

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Ther

2005
Oral clopidogrel load in aspirin-resistant capsular warning syndrome.
    Neurocritical care, 2005, Volume: 2, Issue:2

    Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female

2005
[Cerebral secondary prevention--clopidogrel alone or in combination with ASS].
    Der Internist, 2005, Volume: 46, Issue:11

    Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Huma

2005
Procedure-related complications and early neurological adverse events of unprotected and protected carotid stenting: temporal trends in a consecutive patient series.
    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 2005, Volume: 12, Issue:5

    Topics: Aged; Aspirin; Blood Vessel Prosthesis Implantation; Carotid Artery, Internal; Carotid Stenosis; Clo

2005
Efficacy of dual antiplatelet therapy in cerebrovascular disease as demonstrated by a decline in microembolic signals. A report of eight cases.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 21, Issue:4

    Topics: Aged; Aspirin; Cerebrovascular Disorders; China; Clopidogrel; Drug Therapy, Combination; Embolism; F

2006
Enhanced platelet activation by prolactin in patients with ischemic stroke.
    Thrombosis and haemostasis, 2006, Volume: 96, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Female; Humans; Ischemic Attack, Tran

2006
[Prevention of vascular events after transient ischemic attack or cerebral infarct].
    La Revue du praticien, 2006, Sep-15, Volume: 56, Issue:13

    Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug

2006
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2007, Volume: 34, Issue:2

    Topics: Aged; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dextrans; Dipyri

2007
[Antithrombotic therapy in ischemic stroke and transient ischemic attack].
    Ugeskrift for laeger, 2007, Oct-01, Volume: 169, Issue:40

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents;

2007
Antiplatelet agents for stroke prevention following transient ischemic attack.
    Southern medical journal, 2008, Volume: 101, Issue:1

    Topics: Angioplasty, Balloon; Aspirin; Carotid Artery Diseases; Clopidogrel; Dipyridamole; Drug Therapy, Com

2008
Prediction and prevention of stroke in patients with symptomatic carotid stenosis: the high-risk period and the high-risk patient.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2008, Volume: 35, Issue:3

    Topics: Aspirin; Carotid Stenosis; Clopidogrel; Endarterectomy, Carotid; Humans; Ischemic Attack, Transient;

2008
Monitoring of clopidogrel-related platelet inhibition: correlation of nonresponse with clinical outcome in supra-aortic stenting.
    AJNR. American journal of neuroradiology, 2008, Volume: 29, Issue:4

    Topics: Adult; Aged; Basilar Artery; Carotid Artery, Internal; Clopidogrel; Constriction, Pathologic; Drug M

2008
Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack.
    Stroke, 2008, Volume: 39, Issue:5

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Combinations; Dru

2008
Trends in usage of alternative antiplatelet therapy after stroke and transient ischemic attack.
    Stroke, 2008, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Prescrip

2008
Severe anemia associated with transient ischemic attacks involving vertebrobasilar circulation.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anemia; Clopidogrel; Diagnosis, Differential; Electrocardio

2008
[Transient ischemic attack associated with a calcinosis cerebri syndrome].
    Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1

    Topics: Aged; Brain Diseases; Calcinosis; Clopidogrel; Dysarthria; Humans; Ischemic Attack, Transient; Magne

2008
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
    Ugeskrift for laeger, 2008, Mar-31, Volume: 170, Issue:14

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin;

2008
[Emergency treatment of transient cerebral ischemia].
    Ugeskrift for laeger, 2008, Apr-21, Volume: 170, Issue:17

    Topics: Aspirin; Clopidogrel; Emergency Treatment; Humans; Ischemic Attack, Transient; Platelet Aggregation

2008
Effects of long-term ticlopidine treatment on platelet function and its tolerability in cerebrovascular disease.
    The Journal of international medical research, 1984, Volume: 12, Issue:5

    Topics: Adult; Aged; Anticoagulants; Blood Coagulation Tests; Blood Platelets; Cerebrovascular Disorders; Fe

1984
[Migraine or transient ischemic attacks in a patient with essential thrombocythaemia. Treatment with ticlopidine (author's transl)].
    Annales de medecine interne, 1980, Volume: 131, Issue:2

    Topics: Blood Platelets; Humans; Ischemic Attack, Transient; Male; Middle Aged; Migraine Disorders; Platelet

1980
[Stroke: new perspectives in prevention. Scientific symposium, 24 April 1993, Frankfurt].
    Der Nervenarzt, 1993, Volume: 64, Issue:7 Suppl

    Topics: Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Prog

1993
Delayed neutropenia with ticlopidine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12

    Topics: Aged; Blood Cell Count; Female; Humans; Ischemic Attack, Transient; Neutropenia; Pneumonia; Ticlopid

1994
Platelet activation in the cerebral circulation in different subtypes of ischemic stroke and Binswanger's disease.
    Stroke, 1995, Volume: 26, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cardiovascular Diseases; Cerebral Angiography; Cerebrovascu

1995
Does ticlopidine prevent reversible cerebrovascular ischemic events in women?
    Stroke, 1994, Volume: 25, Issue:4

    Topics: Aspirin; Female; Humans; Ischemic Attack, Transient; Ticlopidine

1994
Guidelines for medical treatment for stroke prevention. American College of Physicians.
    Annals of internal medicine, 1994, Jul-01, Volume: 121, Issue:1

    Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocard

1994
Cost-effectiveness of ticlopidine in preventing stroke in high-risk patients.
    Stroke, 1994, Volume: 25, Issue:6

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Cohort Studies; Cost-Benefit Analysis; Decision Support Te

1994
Ticlopidine hydrochloride and prevention of stroke.
    The Western journal of medicine, 1993, Volume: 159, Issue:2

    Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Ischemic Attack, Trans

1993
Thrombotic thrombocytopenic purpura associated with ticlopidine.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:9

    Topics: Aged; Humans; Ischemic Attack, Transient; Male; Purpura, Thrombotic Thrombocytopenic; Ticlopidine

1993
Ticlopidine-induced prolonged cholestasis.
    Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:12

    Topics: Aged; Aged, 80 and over; Cholestasis; Humans; Ischemic Attack, Transient; Male; Ticlopidine

1993
Phenytoin toxicity associated with ticlopidine administration.
    Archives of internal medicine, 1996, May-27, Volume: 156, Issue:10

    Topics: Aged; Drug Interactions; Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Male; Phenytoin; T

1996
[Thrombotic thrombocytopenic purpura associated with ticlopidine].
    Anales de medicina interna (Madrid, Spain : 1984), 1996, Volume: 13, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Ischemic Attack, Transient; Platelet Aggregation In

1996
The role of antiplatelet therapy in stroke prevention.
    Tennessee medicine : journal of the Tennessee Medical Association, 1997, Volume: 90, Issue:11

    Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Ischemic Attack, Transient; Pl

1997
Secondary prevention of stroke--new trials.
    Scottish medical journal, 1998, Volume: 43, Issue:1

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Dr

1998
[Secondary prevention of recurrent transient ischemic attacks].
    Der Internist, 1998, Volume: 39, Issue:4

    Topics: Anticoagulants; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ischemic At

1998
[Lymphocytic colitis and ticlopidine].
    Gastroenterologie clinique et biologique, 1998, Volume: 22, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Captopril; Colitis; Diarrhea; Female; Humans; Hypertension; Isch

1998
Stent-assisted angioplasty of intracranial vertebrobasilar atherosclerosis: an initial experience.
    Journal of neurosurgery, 2000, Volume: 92, Issue:5

    Topics: Abciximab; Adult; Aged; Angiography; Angioplasty; Antibodies, Monoclonal; Anticoagulants; Aspirin; B

2000
Cost-effectiveness of new antiplatelet regimens used as secondary prevention of stroke or transient ischemic attack.
    Archives of internal medicine, 2000, Oct-09, Volume: 160, Issue:18

    Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Decision Trees; Dipyridamole; Drug Therapy, Combi

2000
Ticlopidine-induced interstitial pulmonary disease: a case report.
    Chest, 2001, Volume: 119, Issue:6

    Topics: Aged; Female; Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Lung Diseases, Interstitial;

2001
Fibroelastoma of the mitral valve as a cause of transient ischemic stroke.
    Arquivos brasileiros de cardiologia, 2001, Volume: 77, Issue:1

    Topics: Adult; Female; Fibroma; Heart Neoplasms; Heart Valve Diseases; Humans; Ischemic Attack, Transient; M

2001
Current strategies of secondary prevention after a cerebrovascular event: the Vienna stroke registry.
    Stroke, 2001, Dec-01, Volume: 32, Issue:12

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation;

2001
Clopidogrel(TM): an alternative to acetylsalicylic acid and ticlopidine in antiplatelet therapy?
    Issues in emerging health technologies, 1999, Issue:6

    Topics: Arteriosclerosis; Canada; Cost-Benefit Analysis; Drug Evaluation; Heart Diseases; Humans; Ischemic A

1999
Vascular event rates in patients with atherosclerotic cerebrovascular disease.
    Archives of neurology, 1992, Volume: 49, Issue:8

    Topics: Age Factors; Aged; Carotid Stenosis; Cerebrovascular Disorders; Epidemiologic Methods; Humans; Intra

1992
[The effects of ticlopidine and nicardipine on the prevention of symptomatic vasospasm after aneurysmal rupture].
    No shinkei geka. Neurological surgery, 1988, Volume: 16, Issue:6

    Topics: Adult; Aged; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; N

1988