ticlopidine has been researched along with Infarct, Lacunar in 19 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among patients with recent lacunar strokes, the addition of clopidogrel to aspirin did not significantly reduce the risk of recurrent stroke and did significantly increase the risk of bleeding and death." | 9.16 | Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. ( Benavente, OR; Coffey, CS; Hart, RG; McClure, LA; Pearce, LA; Szychowski, JM, 2012) |
| "Among patients with recent lacunar strokes, the addition of clopidogrel to aspirin did not significantly reduce the risk of recurrent stroke and did significantly increase the risk of bleeding and death." | 5.16 | Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. ( Benavente, OR; Coffey, CS; Hart, RG; McClure, LA; Pearce, LA; Szychowski, JM, 2012) |
| "Clopidogrel combined with aspirin is routinely prescribed after coronary artery stenting, in patients with acute coronary syndromes, and recently to prevent stroke in patients with acute minor ischemic stroke and TIA." | 4.91 | Effect of addition of clopidogrel to aspirin on subdural hematoma: meta-analysis of randomized clinical trials. ( Bakheet, MF; Hart, RG; Pearce, LA, 2015) |
| "Patients with lacunar stroke and CMBs likely harbor a more advanced form of cerebral small vessel disease in need of efficacious therapeutic strategies." | 2.84 | Microbleeds in the Secondary Prevention of Small Subcortical Strokes Trial: Stroke, mortality, and treatment interactions. ( Anderson, DC; Bazan, C; Benavente, OR; Catanese, L; Hart, RG; Kase, CS; Marti-Fabregas, J; McClure, LA; Pearce, LA; Sharma, M; Shoamanesh, A, 2017) |
| "In patients with a recent lacunar stroke while taking ASA, the addition of clopidogrel did not result in reduction of vascular events vs continuing ASA only." | 2.79 | ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection? ( Anderson, DC; Benavente, OR; Côté, R; Hart, RG; McClure, LA; Talbert, RL; Zhang, Y, 2014) |
| "Among 1244 patients with lacunar stroke (mean age, 63." | 2.79 | C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study. ( Benavente, OR; Coffey, CS; Del Brutto, OH; Elkind, MS; Luna, JM; McClure, LA; Meyer, BC; Pettigrew, LC; Pretell, EJ; Roldan, A; Tapia, J; White, C; Zhang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 19 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shoamanesh, A | 1 |
| Pearce, LA | 8 |
| Bazan, C | 3 |
| Catanese, L | 1 |
| McClure, LA | 6 |
| Sharma, M | 3 |
| Marti-Fabregas, J | 1 |
| Anderson, DC | 6 |
| Kase, CS | 1 |
| Hart, RG | 9 |
| Benavente, OR | 10 |
| Wadiwala, MF | 1 |
| Kamal, AK | 1 |
| Opherk, C | 1 |
| Côté, R | 1 |
| Zhang, Y | 2 |
| Talbert, RL | 1 |
| Castilla-Guerra, L | 1 |
| Sacco, RL | 1 |
| Elkind, MS | 1 |
| Luna, JM | 1 |
| Coffey, CS | 3 |
| Roldan, A | 1 |
| Del Brutto, OH | 1 |
| Pretell, EJ | 1 |
| Pettigrew, LC | 1 |
| Meyer, BC | 1 |
| Tapia, J | 2 |
| White, C | 1 |
| Markun, S | 1 |
| Connolly, SJ | 1 |
| Palacio, S | 1 |
| Hillis, AE | 1 |
| Jacova, C | 1 |
| Bakheet, MF | 1 |
| Nakajima, M | 1 |
| Ohara, N | 1 |
| Field, TS | 4 |
| Asinger, RW | 1 |
| Smyth, NG | 1 |
| De, SK | 1 |
| Spence, JD | 1 |
| Rayner, BL | 1 |
| Odden, MC | 1 |
| Sawaya, BP | 1 |
| White, CL | 1 |
| Peralta, CA | 1 |
| Pergola, PE | 1 |
| Wilson, LK | 1 |
| Arauz, A | 1 |
| Benavente, O | 1 |
| Szychowski, JM | 1 |
| Diener, HC | 1 |
| Weber, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Low-dose Aspirin Therapy in Patients With Non-Cardioembolic Ischemic Stroke and Microbleeds[NCT04504864] | Phase 4 | 400 participants (Anticipated) | Interventional | 2020-10-01 | Recruiting | ||
| Secondary Prevention of Small Subcortical Strokes (SPS3) Trial[NCT00059306] | Phase 3 | 3,020 participants (Actual) | Interventional | 2003-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ticlopidine and Infarct, Lacunar
| Article | Year |
|---|---|
Effect of addition of clopidogrel to aspirin on subdural hematoma: meta-analysis of randomized clinical trials.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; | 2015 |
12 trials available for ticlopidine and Infarct, Lacunar
| Article | Year |
|---|---|
Microbleeds in the Secondary Prevention of Small Subcortical Strokes Trial: Stroke, mortality, and treatment interactions.
Topics: Aspirin; Cerebral Hemorrhage; Clopidogrel; Double-Blind Method; Female; Humans; Magnetic Resonance I | 2017 |
ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection?
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Double-Blind Method; Drug Therapy, Combination; Female; | 2014 |
C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study.
Topics: Aged; Antihypertensive Agents; Aspirin; Biomarkers; Blood Pressure; C-Reactive Protein; Clopidogrel; | 2014 |
Predictors of mortality in patients with lacunar stroke in the secondary prevention of small subcortical strokes trial.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged | 2014 |
Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial.
Topics: Aged; Aspirin; Blood Pressure; Clopidogrel; Cognition; Double-Blind Method; Drug Therapy, Combinatio | 2014 |
Vertebrobasilar ectasia in patients with lacunar stroke: the secondary prevention of small subcortical strokes trial.
Topics: Aged; Basilar Artery; Clopidogrel; Dilatation, Pathologic; Double-Blind Method; Female; Humans; Magn | 2015 |
Left Ventricular Geometry on Transthoracic Echocardiogram and Prognosis after Lacunar Stroke: The SPS3 Trial.
Topics: Aged; Aspirin; Clopidogrel; Echocardiography; Female; Heart Ventricles; Humans; Magnetic Resonance I | 2015 |
Achieved Blood Pressure and Outcomes in the Secondary Prevention of Small Subcortical Strokes Trial.
Topics: Aspirin; Blood Pressure; Blood Pressure Determination; Clopidogrel; Drug Therapy, Combination; Femal | 2016 |
Morphological classification of penetrating artery pontine infarcts and association with risk factors and prognosis: The SPS3 trial.
Topics: Antihypertensive Agents; Aspirin; Cerebral Infarction; Clopidogrel; Constriction, Pathologic; Double | 2016 |
[Branch atheromatous disease: prognosis and management. The SPS3 experience].
Topics: Aspirin; Basilar Artery; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Stroke, Lacun | 2011 |
Effects of clopidogrel added to aspirin in patients with recent lacunar stroke.
Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hem | 2012 |
Clopidogrel added to aspirin adds no benefit but bleeding risk in patients with recent lacunar stroke.
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combinati | 2013 |
6 other studies available for ticlopidine and Infarct, Lacunar
| Article | Year |
|---|---|
My patient had a small vessel stroke, are two antiplatelet agents better than one?
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggrega | 2013 |
[Not Available].
Topics: Aspirin; Female; Humans; Male; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine | 2013 |
Treating lacunar strokes occurring on aspirin: adding clopidogrel is not the simple solution.
Topics: Aspirin; Clopidogrel; Female; Humans; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; | 2014 |
[Adding clopidogrel after stroke while on aspirin-does not help, only hurts].
Topics: Aspirin; Female; Humans; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Stroke, Lacu | 2014 |
Blood pressure control after stroke: too little, too late, or too soon to tell?
Topics: Aspirin; Blood Pressure; Clopidogrel; Cognition; Female; Humans; Male; Platelet Aggregation Inhibito | 2014 |
J Curve and Cuff Artefact, and Diagnostic Inertia in Resistant Hypertension.
Topics: Aspirin; Blood Pressure; Female; Humans; Hypertension; Male; Secondary Prevention; Stroke, Lacunar; | 2016 |