Page last updated: 2024-11-05

ticlopidine and Hyperemia

ticlopidine has been researched along with Hyperemia in 3 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Research Excerpts

ExcerptRelevanceReference
"Clopidogrel reduces long-term ischemic events in patients with acute coronary syndrome or stable angina (SA) undergoing percutaneous coronary intervention (PCI)."7.77Relationship between peripheral arterial reactive hyperemia and residual platelet reactivity after 600 mg clopidogrel. ( Barbato, E; Bartunek, J; Cuisset, T; De Bruyne, B; Dierickx, K; Hamilos, M; Mangiacapra, F; Meeus, P; Muller, O; Ntalianis, A; Sarno, G; Trana, C; Wijns, W, 2011)
"Clopidogrel reduces long-term ischemic events in patients with acute coronary syndrome or stable angina (SA) undergoing percutaneous coronary intervention (PCI)."3.77Relationship between peripheral arterial reactive hyperemia and residual platelet reactivity after 600 mg clopidogrel. ( Barbato, E; Bartunek, J; Cuisset, T; De Bruyne, B; Dierickx, K; Hamilos, M; Mangiacapra, F; Meeus, P; Muller, O; Ntalianis, A; Sarno, G; Trana, C; Wijns, W, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dahmus, JD1
Bruning, RS1
Kenney, WL1
Alexander, LM1
Salimi, S1
Lewis, JP1
Yerges-Armstrong, LM1
Mitchell, BD1
Saeed, F1
O'Connell, JR1
Perry, JA1
Ryan, KA1
Shuldiner, AR1
Parsa, A1
Hamilos, M1
Muller, O1
Ntalianis, A1
Trana, C1
Bartunek, J1
Sarno, G1
Mangiacapra, F1
Dierickx, K1
Meeus, P1
Cuisset, T1
De Bruyne, B1
Wijns, W1
Barbato, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacogenomics of Anti-Platelet Interventions (The PAPI Study)[NCT00799396]Phase 4682 participants (Actual)Interventional2006-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in Platelet Function in Response to Clopidogrel

Baseline minus post clopidogrel/pre-aspirin platelet rich plasma (PRP) maximum aggregation. (NCT00799396)
Timeframe: Measured at baseline, and after clopidogrel treatment

Interventionpercentage of maximum aggregation change (Mean)
PRP ADP 20PRP Collagen 5
Overall Study38.5114.06

Changes in Platelet Function in Response to Clopidogrel Plus Aspirin

Baseline minus post clopidogrel/post-aspirin platelet rich plasma (PRP) maximum aggregation (NCT00799396)
Timeframe: Measured at baseline, and after clopidogrel plus aspirin treatment

Interventionpercentage of max aggregation change (Mean)
PRP ADP 20PRP Collagen 5
Overall Study41.2156.64

Trials

2 trials available for ticlopidine and Hyperemia

ArticleYear
Oral clopidogrel improves cutaneous microvascular function through EDHF-dependent mechanisms in middle-aged humans.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Aug-15, Volume: 305, Issue:4

    Topics: Administration, Oral; Analysis of Variance; Aspirin; Biological Factors; Blood Flow Velocity; Clopid

2013
Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation.
    Journal of the American Heart Association, 2016, 10-31, Volume: 5, Issue:11

    Topics: Adult; Aged; Clopidogrel; Cytochrome P-450 CYP2C19; Endothelium, Vascular; Female; Genotype; Healthy

2016

Other Studies

1 other study available for ticlopidine and Hyperemia

ArticleYear
Relationship between peripheral arterial reactive hyperemia and residual platelet reactivity after 600 mg clopidogrel.
    Journal of thrombosis and thrombolysis, 2011, Volume: 32, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Coronary Artery Disease; Endothelium, Vascular; Female;

2011