ticlopidine has been researched along with Hip Fractures in 34 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
| Excerpt | Relevance | Reference |
|---|---|---|
| " the pharmacokinetics of clopidogrel do not allow for bleeding time to return to normal until the drug has been discontinued for five days." | 7.78 | Operative treatment of hip fractures in patients on clopidogrel: a case-control study. ( Chaput, CD; Patel, KV; Probe, RA; Wallace, HC, 2012) |
| "Of 1381 patients admitted with hip fractures, 114 were receiving regular clopidogrel therapy with a median age of 83." | 7.77 | Perioperative management of clopidogrel therapy: the effects on in-hospital cardiac morbidity in older patients with hip fractures. ( Collyer, TC; Corcoran, T; Kilshaw, L; Reynolds, HC; Truyens, E, 2011) |
| "To assess the outcomes of patients with acute proximal hip fractures who were taking Clopidogrel." | 7.75 | The management of patients with hip fractures who are taking Clopidogrel. ( Gonski, PN; Sim, W, 2009) |
| " The aim of this study was to ascertain whether it is necessary to stop clopidogrel preoperatively to avoid postoperative complications following hip hemiarthroplasty surgery in patients with intracapsular hip fracture." | 3.79 | Is discontinuation of clopidogrel necessary for intracapsular hip fracture surgery? Analysis of 102 hemiarthroplasties. ( Hossain, FS; Koch, L; Rambani, R; Ribee, H, 2013) |
| " the pharmacokinetics of clopidogrel do not allow for bleeding time to return to normal until the drug has been discontinued for five days." | 3.78 | Operative treatment of hip fractures in patients on clopidogrel: a case-control study. ( Chaput, CD; Patel, KV; Probe, RA; Wallace, HC, 2012) |
| "Of 1381 patients admitted with hip fractures, 114 were receiving regular clopidogrel therapy with a median age of 83." | 3.77 | Perioperative management of clopidogrel therapy: the effects on in-hospital cardiac morbidity in older patients with hip fractures. ( Collyer, TC; Corcoran, T; Kilshaw, L; Reynolds, HC; Truyens, E, 2011) |
| "To assess the outcomes of patients with acute proximal hip fractures who were taking Clopidogrel." | 3.75 | The management of patients with hip fractures who are taking Clopidogrel. ( Gonski, PN; Sim, W, 2009) |
| "Early surgery appears safe for patients with hip fracture though there may be a small increase in the rate of blood transfusion." | 2.52 | Is early hip fracture surgery safe for patients on clopidogrel? Systematic review, meta-analysis and meta-regression. ( Doleman, B; Moppett, IK, 2015) |
| " Proton pump inhibitors cause few adverse effects with short-term use; however, long-term use has been scrutinized for appropriateness, drug-drug interactions, and the potential for adverse effects (e." | 2.48 | Reducing adverse effects of proton pump inhibitors. ( Ament, PW; Dicola, DB; James, ME, 2012) |
| " Despite the widespread usage and favorable safety profile, much attention has focused recently on potential adverse events associated with use." | 2.46 | Safety of proton pump inhibitors: current evidence for osteoporosis and interaction with antiplatelet agents. ( Johnson, DA, 2010) |
| "Early hip fracture surgery is safe for elderly patients within 5 days of clopidogrel withdrawal, without increased perioperative blood loss, transfusion requirement, complications, and mortality compared with patients not taking antiplatelet drugs." | 1.62 | Safety of early surgery for geriatric hip fracture patients taking clopidogrel: a retrospective case-control study of 120 patients in China. ( Li, B; Wang, G; Wu, XB; Yang, MH; Yao, DC; Zhang, P; Zhang, WC; Zhou, Y; Zhu, SW, 2021) |
| "Postoperative complications were similar in the 2 groups." | 1.46 | Poor prognosis after surgery for intertrochanteric fracture in elderly patients with clopidogrel treatment: A cohort study. ( Chen, X; Liu, Z; Ren, J; Sun, T; Wang, J; Wang, X; Zhang, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 26 (76.47) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Tescione, M | 1 |
| Vadalà, E | 1 |
| Marano, G | 1 |
| Battaglia, E | 1 |
| Bruni, A | 1 |
| Garofalo, E | 1 |
| Longhini, F | 1 |
| Rovida, S | 1 |
| Polimeni, N | 1 |
| Squillaci, R | 1 |
| Lascala, S | 1 |
| Franco, G | 1 |
| Labate, D | 1 |
| Caracciolo, M | 1 |
| Macheda, S | 1 |
| Yang, MH | 1 |
| Li, B | 1 |
| Yao, DC | 1 |
| Zhou, Y | 1 |
| Zhang, WC | 1 |
| Wang, G | 1 |
| Zhang, P | 1 |
| Zhu, SW | 1 |
| Wu, XB | 1 |
| Pailleret, C | 1 |
| Ait Hamou, Z | 1 |
| Rosencher, N | 2 |
| Samama, CM | 1 |
| Eyraud, V | 1 |
| Chilot, F | 1 |
| Baillard, C | 1 |
| Zhang, J | 1 |
| Chen, X | 1 |
| Wang, J | 1 |
| Liu, Z | 1 |
| Wang, X | 1 |
| Ren, J | 1 |
| Sun, T | 1 |
| Hossain, FS | 1 |
| Rambani, R | 1 |
| Ribee, H | 1 |
| Koch, L | 1 |
| Wallace, HC | 1 |
| Probe, RA | 1 |
| Chaput, CD | 1 |
| Patel, KV | 1 |
| Lee, T | 1 |
| Lee, R | 1 |
| Callender, R | 1 |
| Altamirano, A | 1 |
| Tezino, T | 1 |
| Pivalizza, EG | 1 |
| Cattano, D | 1 |
| Al Khudairy, A | 1 |
| Al-Hadeedi, O | 1 |
| Sayana, MK | 1 |
| Galvin, R | 1 |
| Quinlan, JF | 1 |
| Ariyaratnam, P | 1 |
| McLean, LA | 1 |
| Kotidis, K | 1 |
| Loubani, M | 1 |
| Manaqibwala, MI | 1 |
| Butler, KA | 1 |
| Sagebien, CA | 1 |
| Sood, A | 1 |
| Trinh, QD | 1 |
| Doleman, B | 1 |
| Moppett, IK | 1 |
| Zehir, S | 1 |
| Zehir, R | 1 |
| Sarak, T | 1 |
| Purushothaman, B | 2 |
| Webb, M | 1 |
| Weusten, A | 1 |
| Bonczek, S | 1 |
| Ramaskandhan, J | 1 |
| Nanu, A | 1 |
| Mattesi, L | 1 |
| Noailles, T | 1 |
| Rouvillain, JL | 1 |
| Johansen, A | 1 |
| White, J | 1 |
| Turk, A | 1 |
| Sim, W | 1 |
| Gonski, PN | 1 |
| Johnson, DA | 1 |
| Haidar, R | 1 |
| Taher, AT | 1 |
| Chechik, O | 2 |
| Thein, R | 1 |
| Fichman, G | 1 |
| Haim, A | 1 |
| Tov, TB | 1 |
| Steinberg, EL | 1 |
| Scholl, S | 1 |
| Dellon, ES | 1 |
| Shaheen, NJ | 1 |
| Collyer, TC | 1 |
| Reynolds, HC | 1 |
| Truyens, E | 1 |
| Kilshaw, L | 1 |
| Corcoran, T | 1 |
| Maheshwari, R | 1 |
| Acharya, M | 1 |
| Monda, M | 1 |
| Pandey, R | 1 |
| Amar, E | 1 |
| Khashan, M | 1 |
| Kadar, A | 1 |
| Rosenblatt, Y | 1 |
| Maman, E | 1 |
| Collinge, CA | 1 |
| Kelly, KC | 1 |
| Little, B | 1 |
| Weaver, T | 1 |
| Schuster, RD | 1 |
| Ament, PW | 1 |
| Dicola, DB | 1 |
| James, ME | 1 |
| Wordsworth, DR | 1 |
| Halsey, T | 1 |
| Griffiths, R | 1 |
| Parker, MJ | 1 |
| Feely, MA | 1 |
| Mabry, TM | 1 |
| Lohse, CM | 1 |
| Sems, SA | 1 |
| Mauck, KF | 1 |
| Inman, DS | 1 |
| Michla, Y | 1 |
| Partington, PF | 1 |
| Harty, JA | 1 |
| McKenna, P | 1 |
| Moloney, D | 1 |
| D'Souza, L | 1 |
| Masterson, E | 1 |
| Lavelle, WF | 1 |
| Demers Lavelle, EA | 1 |
| Uhl, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Platelet Aggregometry to Drive the Surgical Timing in Elderlies With Hip Fracture and Receiving Clopidogrel.[NCT04642209] | 9 participants (Anticipated) | Observational | 2020-12-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for ticlopidine and Hip Fractures
| Article | Year |
|---|---|
Is early hip fracture surgery safe for patients on clopidogrel? Systematic review, meta-analysis and meta-regression.
Topics: Aged; Aged, 80 and over; Anticoagulants; Blood Transfusion; Clopidogrel; Contraindications; Cross-Se | 2015 |
Discontinuation of Plavix
Topics: Blood Loss, Surgical; Clopidogrel; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Postopera | 2016 |
Safety of proton pump inhibitors: current evidence for osteoporosis and interaction with antiplatelet agents.
Topics: Clopidogrel; Cytochrome P-450 Enzyme System; Drug Interactions; Evidence-Based Medicine; Hip Fractur | 2010 |
Reducing adverse effects of proton pump inhibitors.
Topics: Anemia, Iron-Deficiency; Clopidogrel; Clostridioides difficile; Critical Care; Diarrhea; Drug Intera | 2012 |
30 other studies available for ticlopidine and Hip Fractures
| Article | Year |
|---|---|
Platelet aggregometry for hip fracture surgery in patients treated with clopidogrel: a pilot study.
Topics: Adenosine Diphosphate; Blood Platelets; Clopidogrel; Hip Fractures; Humans; Pilot Projects; Platelet | 2022 |
Safety of early surgery for geriatric hip fracture patients taking clopidogrel: a retrospective case-control study of 120 patients in China.
Topics: Aged; Case-Control Studies; Clopidogrel; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Ret | 2021 |
A retrospective comparison between delayed and early hip fracture surgery in patients taking clopidogrel: same total bleeding but different timing of blood transfusion.
Topics: Aged; Aged, 80 and over; Blood Transfusion; Clopidogrel; Female; Fracture Fixation, Internal; Hemiar | 2017 |
Poor prognosis after surgery for intertrochanteric fracture in elderly patients with clopidogrel treatment: A cohort study.
Topics: Aged; Blood Loss, Surgical; Blood Transfusion; Cardiovascular Diseases; China; Clopidogrel; Cohort S | 2017 |
Is discontinuation of clopidogrel necessary for intracapsular hip fracture surgery? Analysis of 102 hemiarthroplasties.
Topics: Aged; Aged, 80 and over; Blood Transfusion; Clopidogrel; Comorbidity; Databases, Factual; Female; He | 2013 |
Operative treatment of hip fractures in patients on clopidogrel: a case-control study.
Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Case-Control Studies; Clopidogrel; | 2012 |
Ask the doctors. I recently had a drug-eluting stent placed in one of my coronary arteries after an episode of severe chest pain. My doctor told me I had to take Plavix every day. Now I feel perfectly fine-except for my right hip. I need a hip replace
Topics: Anticoagulants; Clopidogrel; Coronary Disease; Health Behavior; Hip Fractures; Humans; Platelet Aggr | 2013 |
Is it possible? Predicting complications and morbidity in surgical patients on clopidogrel therapy with Thrombelastography Platelet Mapping.
Topics: Female; Hemorrhage; Hip Fractures; Humans; Male; Postoperative Complications; Ticlopidine | 2014 |
Withholding clopidogrel for 3 to 6 versus 7 days or more before surgery in hip fracture patients.
Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Clopidogrel; Female; Hemorrhage; Hip Fractures; Human | 2013 |
Thromboelastography platelet mapping for surgical patients: lessons from cardiac surgery.
Topics: Female; Hemorrhage; Hip Fractures; Humans; Male; Postoperative Complications; Ticlopidine | 2014 |
Complications of hip fracture surgery on patients receiving clopidogrel therapy.
Topics: Aged; Aged, 80 and over; Clopidogrel; Female; Hemiarthroplasty; Hip Fractures; Humans; Male; Platele | 2014 |
Perioperative aspirin: to give or not to give?
Topics: Aspirin; Blood Transfusion; Coronary Artery Bypass; Coronary Disease; Female; Fibrinolytic Agents; H | 2014 |
Early surgery is feasible in patients with hip fractures who are on clopidogrel therapy.
Topics: Aged; Aged, 80 and over; Blood Transfusion; Clopidogrel; Female; Femoral Neck Fractures; Hip Fractur | 2015 |
Decision making on timing of surgery for hip fracture patients on clopidogrel.
Topics: Aged, 80 and over; Blood Transfusion; Clopidogrel; Contraindications; Decision Making; Female; Hemog | 2016 |
Clopidogrel therapy--implications for hip fracture surgery.
Topics: Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Drug Administration Schedule; Follow-Up Studie | 2008 |
The management of patients with hip fractures who are taking Clopidogrel.
Topics: Aged; Aged, 80 and over; Clopidogrel; Female; Hip Fractures; Humans; Male; Middle Aged; Platelet Agg | 2009 |
How long should we delay hip fracture surgery for elderly patients on clopidogrel?
Topics: Aged; Clopidogrel; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2011 |
The effect of clopidogrel and aspirin on blood loss in hip fracture surgery.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Drug Therapy | 2011 |
Treatment of GERD and proton pump inhibitor use in the elderly: practical approaches and frequently asked questions.
Topics: Adenocarcinoma; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aspirin; Barrett Esop | 2011 |
Perioperative management of clopidogrel therapy: the effects on in-hospital cardiac morbidity in older patients with hip fractures.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Blood Transfusion; Clopidogrel; Female; Hip Fractu | 2011 |
Factors influencing mortality in patients on antiplatelet agents presenting with proximal femoral fractures.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cerebrovascular Disorders; Clopidogrel; Com | 2011 |
In support of early surgery for hip fractures sustained by elderly patients taking clopidogrel: a retrospective study.
Topics: Aged, 80 and over; Clopidogrel; Female; Hip Fractures; Humans; Male; Platelet Aggregation; Platelet | 2012 |
The effects of clopidogrel (Plavix) and other oral anticoagulants on early hip fracture surgery.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies; | 2012 |
Side effects of proton pump inhibitors.
Topics: Clopidogrel; Diarrhea; Drug Interactions; Gastroesophageal Reflux; Hip Fractures; Humans; Platelet A | 2012 |
Clopidogrel has no effect on mortality from hip fracture.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Aspirin; Bl | 2013 |
Safety of clopidogrel in hip fracture surgery.
Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Case-Control Studies; Clopidogrel; Cohort Studies; Fe | 2013 |
Perioperative management of trauma patients admitted on clopidogrel (Plavix). A survey of orthopaedic departments across the United Kingdom.
Topics: Clinical Protocols; Clopidogrel; Drug Administration Schedule; Evidence-Based Medicine; Health Care | 2007 |
Anti-platelet agents and surgical delay in elderly patients with hip fractures.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Hip Fractures; Humans; Male; Platelet Aggrega | 2007 |
Operative delay for orthopedic patients on clopidogrel (plavix): a complete lack of consensus.
Topics: Adult; Clopidogrel; Emergency Treatment; Female; Fracture Fixation, Internal; Health Care Surveys; H | 2008 |
Anti-platelet agents and surgical delay in elderly patients with hip fractures.
Topics: Aged; Aspirin; Bleeding Time; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Hip Fractures; Hum | 2008 |