ticlopidine has been researched along with Hepatitis B, Chronic in 4 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Hepatitis B, Chronic: INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Built on these observations, a recent preclinical study took advantage of a previously established hepatitis B virus (HBV) transgenic mouse model of immune-mediated chronic hepatitis that progresses to hepatocellular carcinoma (HCC), to demonstrate that clinically achievable doses of the anti-platelet drugs aspirin and clopidogrel - administered continuously after the onset of liver disease - can prevent hepatocarcinogenesis and greatly improve overall survival." | 3.79 | Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma. ( Guidotti, LG; Iannacone, M; Sitia, G, 2013) |
| "Recurrence of hepatocellular carcinoma (HCC) with unsatisfactory survival is common after surgical resection." | 1.43 | Antiplatelet Therapy is Associated with a Better Prognosis for Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma after Liver Resection. ( Chao, Y; Chen, CC; Chen, TJ; Hu, YW; Huang, YH; Huo, TI; Lee, PC; Lin, HC; Liu, CJ; Su, CW; Wu, JC; Yeh, CM, 2016) |
| "Treatment with aspirin and clopidogrel during the chronic phase of the disease diminished the number of intrahepatic HBV-specific CD8(+) T cells and HBV-nonspecific inflammatory cells, the severity of liver fibrosis, and the development of HCC." | 1.38 | Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. ( Aiolfi, R; Chisari, FV; Di Lucia, P; Esposito, A; Fiocchi, A; Guidotti, LG; Iannacone, M; Mainetti, M; Mingozzi, F; Ruggeri, ZM; Sitia, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sitia, G | 2 |
| Iannacone, M | 2 |
| Guidotti, LG | 2 |
| Lee, PC | 1 |
| Yeh, CM | 1 |
| Hu, YW | 1 |
| Chen, CC | 1 |
| Liu, CJ | 1 |
| Su, CW | 1 |
| Huo, TI | 1 |
| Huang, YH | 1 |
| Chao, Y | 1 |
| Chen, TJ | 1 |
| Lin, HC | 1 |
| Wu, JC | 1 |
| Aiolfi, R | 1 |
| Di Lucia, P | 1 |
| Mainetti, M | 1 |
| Fiocchi, A | 1 |
| Mingozzi, F | 1 |
| Esposito, A | 1 |
| Ruggeri, ZM | 1 |
| Chisari, FV | 1 |
| Greenhill, C | 1 |
4 other studies available for ticlopidine and Hepatitis B, Chronic
| Article | Year |
|---|---|
Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma.
Topics: Animals; Aspirin; Blood Platelets; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Proli | 2013 |
Antiplatelet Therapy is Associated with a Better Prognosis for Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma after Liver Resection.
Topics: Adult; Aged; Aspirin; Carcinoma, Hepatocellular; Clopidogrel; Disease-Free Survival; Female; Gastroi | 2016 |
Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.
Topics: Analysis of Variance; Animals; Aspirin; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Clopi | 2012 |
Hepatocellular carcinoma: could antiplatelet drugs be used to prevent HBV-associated hepatocellular carcinoma?
Topics: Animals; Carcinoma, Hepatocellular; Chemoprevention; Clopidogrel; Disease Models, Animal; Disease Pr | 2012 |