Page last updated: 2024-11-05

ticlopidine and Heart Failure

ticlopidine has been researched along with Heart Failure in 59 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"By inhibiting prostaglandins, aspirin may be deleterious in heart failure (HF) and/or may counteract angiotensin-converting enzyme (ACE) inhibitor efficacy."9.12Effects of aspirin and clopidogrel on plasma brain natriuretic peptide in patients with heart failure receiving ACE inhibitors. ( Bergmann, JF; Cohen-Solal, A; Duboc, D; Fulla, Y; Mahé, I; Meune, C; Mouly, S; Simoneau, G; Wahbi, K; Weber, S, 2007)
"The benefits of taking of aspirin, clopidogrel, and warfarin in relation to cardiovascular mortality and re-hospitalization in chronic heart failure (HF) patients have been called into question."7.78Aspirin, clopidogrel, and warfarin use and outcomes in a cohort of 580 patients discharged after hospitalization for decompensated heart failure. ( Celikyurt, U; Ertaş, G; Kılıç, T; Kozdağ, G; Sahin, T; Ural, D; Yaymacı, M, 2012)
"We studied the association of clopidogrel with mortality in acute myocardial infarction (AMI) patients with heart failure (HF) not receiving percutaneous coronary intervention (PCI)."7.76Increased mortality associated with low use of clopidogrel in patients with heart failure and acute myocardial infarction not undergoing percutaneous coronary intervention: a nationwide study. ( Abildstrøm, SZ; Bonde, L; Bretler, DM; Fosbøl, EL; Gislason, GH; Hansen, PR; Kober, L; Olesen, J; Schramm, TK; Sorensen, R; Torp-Pedersen, C; Weeke, P, 2010)
"The ability of clopidogrel to inhibit platelet function in patients with congestive heart failure (CHF) was proved by the PLUTO-CHF trial."7.74Does heart failure etiology, New York Heart Association class, or ejection fraction affect the ability of clopidogrel to inhibit heightened platelet activity? ( Malinin, AI; O'Connor, CM; Oshrine, BR; Sane, DC; Serebruany, VL, 2007)
"Transient pancytopenia as an adverse hematologic reaction due to ticlopidine."7.73[Transient pancytopenia due to ticlopidine--a case report]. ( Barg, W; Biełous-Wilk, A; Chmielowicz, B; Grabowski, M; Kopec, A; Panaszek, B, 2005)
" Chronic use of mild platelet inhibitors could therefore represent an independent avenue to improve morbidity, mortality, and quality of life in this expanding population."6.71Effects of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: the Plavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) trial. ( Jerome, SD; Lowry, DR; Malinin, AI; Morgan, AW; O'connor, CM; Sane, DC; Serebruany, VL; Steinhubl, SR; Tanguay, JF, 2003)
"Our understanding of the pathogenesis of congestive heart failure (CHF) has improved remarkably in recent years."6.42Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel? ( Dzhanashvili, AI; Malinin, AI; O'Connor, CM; Sane, DC; Serebruany, VL, 2003)
" In conclusion, clopidogrel improved endothelial function and NO bioavailability in heart failure."5.37Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure. ( Bauersachs, J; Fraccarollo, D; Loch, E; Neuser, J; Pförtsch, S; Schäfer, A; Vogt, C, 2011)
"Participants in the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE) trials with HF, but not randomized to oral anticoagulation, were categorized as having preserved versus reduced ejection fraction."5.20Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure. ( Connolly, SJ; Hart, RG; Healey, JS; Hohnloser, SH; McAlister, FA; Pfeffer, MA; Sandhu, RK; Yuan, F; Yusuf, S, 2015)
"The relationships between Q waves that appear during the acute phase of ST-elevation myocardial infarction (STEMI), clinical characteristics, ST-segment resolution (STRes), and clopidogrel therapy in patients treated with fibrinolysis are not well described."5.19Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: observations from the CLARITY-TIMI 28 trial. ( Cannon, CP; Gibson, CM; Giugliano, RP; Morrow, DA; Sabatine, MS; Scirica, BM; Sloan, S; Waks, JW; Wiviott, SD, 2014)
"By inhibiting prostaglandins, aspirin may be deleterious in congestive heart failure (CHF) and/or partially counteract the efficacy of angiotensin-converting enzyme inhibitors (ACEI)."5.12Comparative effect of aspirin and clopidogrel on arterial function in CHF. ( Bergmann, JF; Champion, K; Duboc, D; Lévy, BI; Mahé, I; Meune, C; Mourad, JJ; Simoneau, G; Solal, AC; Weber, S, 2006)
"By inhibiting prostaglandins, aspirin may be deleterious in heart failure (HF) and/or may counteract angiotensin-converting enzyme (ACE) inhibitor efficacy."5.12Effects of aspirin and clopidogrel on plasma brain natriuretic peptide in patients with heart failure receiving ACE inhibitors. ( Bergmann, JF; Cohen-Solal, A; Duboc, D; Fulla, Y; Mahé, I; Meune, C; Mouly, S; Simoneau, G; Wahbi, K; Weber, S, 2007)
" In the last few years, cilostazol, a phosphodiesterase (PDE) 3 inhibitor, has been tested in the setting of acute coronary syndromes: it exerts not only anti-platelet actions, but also pleiotropic effects, including inhibition on neointimal hyperplasia, therefore preventing both stent restenosis and thrombosis."4.88Cilostazol and primary-PCI: mirage or good alternative? ( Crea, F; D'Amario, D; Porto, I, 2012)
" Due to previous atrial fibrillation and ischaemic heart disease, this patient was treated with both dabigatran and clopidogrel."3.88Left ventricular mural thrombus despite treatment with dabigatran and clopidogrel. ( Fredgart, M; Gill, S, 2018)
"We conducted a nested case-control study of Ontarians aged 66 years and older treated with clopidogrel between September 1 2003 and March 31 2013 following acute myocardial infarction."3.81A population-based study of the drug interaction between clopidogrel and angiotensin converting enzyme inhibitors. ( Cressman, AM; Fernandes, KA; Gomes, T; Juurlink, DN; Macdonald, EM; Mamdani, MM; Paterson, JM, 2015)
"The benefits of taking of aspirin, clopidogrel, and warfarin in relation to cardiovascular mortality and re-hospitalization in chronic heart failure (HF) patients have been called into question."3.78Aspirin, clopidogrel, and warfarin use and outcomes in a cohort of 580 patients discharged after hospitalization for decompensated heart failure. ( Celikyurt, U; Ertaş, G; Kılıç, T; Kozdağ, G; Sahin, T; Ural, D; Yaymacı, M, 2012)
"We studied the association of clopidogrel with mortality in acute myocardial infarction (AMI) patients with heart failure (HF) not receiving percutaneous coronary intervention (PCI)."3.76Increased mortality associated with low use of clopidogrel in patients with heart failure and acute myocardial infarction not undergoing percutaneous coronary intervention: a nationwide study. ( Abildstrøm, SZ; Bonde, L; Bretler, DM; Fosbøl, EL; Gislason, GH; Hansen, PR; Kober, L; Olesen, J; Schramm, TK; Sorensen, R; Torp-Pedersen, C; Weeke, P, 2010)
"The ability of clopidogrel to inhibit platelet function in patients with congestive heart failure (CHF) was proved by the PLUTO-CHF trial."3.74Does heart failure etiology, New York Heart Association class, or ejection fraction affect the ability of clopidogrel to inhibit heightened platelet activity? ( Malinin, AI; O'Connor, CM; Oshrine, BR; Sane, DC; Serebruany, VL, 2007)
"Transient pancytopenia as an adverse hematologic reaction due to ticlopidine."3.73[Transient pancytopenia due to ticlopidine--a case report]. ( Barg, W; Biełous-Wilk, A; Chmielowicz, B; Grabowski, M; Kopec, A; Panaszek, B, 2005)
" Chronic use of mild platelet inhibitors could therefore represent an independent avenue to improve morbidity, mortality, and quality of life in this expanding population."2.71Effects of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: the Plavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) trial. ( Jerome, SD; Lowry, DR; Malinin, AI; Morgan, AW; O'connor, CM; Sane, DC; Serebruany, VL; Steinhubl, SR; Tanguay, JF, 2003)
"Our understanding of the pathogenesis of congestive heart failure (CHF) has improved remarkably in recent years."2.42Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel? ( Dzhanashvili, AI; Malinin, AI; O'Connor, CM; Sane, DC; Serebruany, VL, 2003)
" In conclusion, clopidogrel improved endothelial function and NO bioavailability in heart failure."1.37Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure. ( Bauersachs, J; Fraccarollo, D; Loch, E; Neuser, J; Pförtsch, S; Schäfer, A; Vogt, C, 2011)
"Chronic myocardial ischemia was induced using a minimally invasive model in 16 landrace pigs."1.37Gene therapy with iNOS enhances regional contractility and reduces delayed contrast enhancement in a model of postischemic congestive heart failure. ( Abegunewardene, N; Gori, T; Horstick, G; Kreitner, KF; Lehr, HA; Münzel, T; Schmidt, KH; Schreiber, LM; Vosseler, M, 2011)
"Heart failure is a significant public health problem."1.36Antithrombotic therapies in patients with heart failure: hypothesis formulation from a research database. ( Burton, P; Cheng, M; Griffin, G; Lee, MS; Oppenheimer, L; Plotnikov, AN; Weinstein, R; Yuan, Z; Zhang, J; Zolynas, R, 2010)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.69)18.7374
1990's2 (3.39)18.2507
2000's24 (40.68)29.6817
2010's30 (50.85)24.3611
2020's2 (3.39)2.80

Authors

AuthorsStudies
Komiyama, M1
Agewall, S1
Hasegawa, K1
Marcano, AL1
Lugo, LM1
Besteiro, A1
Gomez-Lara, J1
Roura, G1
Fuentes, L1
Gracida, M1
Teruel, L1
Romaguera, R1
Sosa, SG1
Cequier, Á1
Gómez-Hospital, JA1
Comin-Colet, J1
Ferreiro, JL1
Shavadia, J1
Welsh, R1
Gershlick, A1
Zheng, Y1
Huber, K2
Halvorsen, S2
Steg, PG1
Van de Werf, F2
Armstrong, PW4
Consolo, F1
Pozzi, L1
Sferrazza, G1
Della Valle, P1
D'Angelo, A1
Slepian, MJ1
Pappalardo, F1
Fredgart, M1
Gill, S1
Gershlick, AH1
Goldstein, P1
Wilcox, R1
Danays, T1
Lambert, Y1
Sulimov, V1
Rosell Ortiz, F1
Ostojic, M2
Welsh, RC1
Carvalho, AC1
Nanas, J1
Arntz, HR1
Grajek, S1
Fresco, C1
Bluhmki, E1
Regelin, A1
Vandenberghe, K1
Bogaerts, K1
Hildemann, SK1
Schulz, C1
Fraccarollo, D2
Schöpp, C1
Flierl, U1
Wissel, K1
Pelisek, J1
Massberg, S1
Bauersachs, J2
Schäfer, A2
Waks, JW1
Sabatine, MS1
Cannon, CP1
Morrow, DA1
Gibson, CM1
Wiviott, SD1
Giugliano, RP1
Sloan, S1
Scirica, BM1
Maggioni, AP1
Sandhu, RK1
Hohnloser, SH1
Pfeffer, MA1
Yuan, F1
Hart, RG1
Yusuf, S1
Connolly, SJ1
McAlister, FA1
Healey, JS1
Pacholewicz, J1
Kuliczkowski, W1
Kaczmarski, J1
Zakliczyński, M1
Garbacz, M1
Zembala, M1
Serebruany, V1
Cressman, AM1
Macdonald, EM1
Fernandes, KA1
Gomes, T1
Paterson, JM1
Mamdani, MM1
Juurlink, DN1
Dias, A1
Franco, E1
Koshkelashvili, N1
Bhalla, V1
Pressman, GS1
Hebert, K1
Figueredo, VM1
Otoshi, T1
Kataoka, Y1
Nakagawa, A1
Otsuka, K1
Tomii, K1
Buck, J1
Kaboli, P1
Gage, BF1
Cram, P1
Vaughan Sarrazin, MS1
Ozmete, O1
Bali, C1
Ergenoglu, P1
Suner, HI1
Aribogan, A1
Ghodsizad, A1
Badiye, A1
Zeriouh, M1
Pae, W1
Koerner, MM1
Loebe, M1
Massie, BM2
Collins, JF2
Ammon, SE2
Cleland, JG3
Ezekowitz, M2
Jafri, SM2
Krol, WF2
O'Connor, CM5
Schulman, KA2
Teo, K2
Warren, SR1
Hoppe, UC2
Kan, LP1
Chu, KM1
Lin, GM1
Bonde, L1
Sorensen, R1
Fosbøl, EL1
Abildstrøm, SZ1
Hansen, PR1
Kober, L1
Schramm, TK1
Bretler, DM1
Weeke, P1
Olesen, J1
Torp-Pedersen, C1
Gislason, GH1
Serebruany, VL4
Ponikowski, P1
Ronco, C1
Anker, SD1
Yuan, Z1
Weinstein, R1
Zhang, J1
Cheng, M1
Griffin, G1
Zolynas, R1
Plotnikov, AN1
Lee, MS1
Oppenheimer, L1
Burton, P1
Pförtsch, S1
Loch, E1
Neuser, J1
Vogt, C1
Kukin, M1
Messerli, FH1
Awad, HH1
Zubaid, M1
Alsheikh-Ali, AA1
Al Suwaidi, J1
Anderson, FA1
Gore, JM1
Goldberg, RJ1
Kozdağ, G1
Yaymacı, M1
Ertaş, G1
Celikyurt, U1
Sahin, T1
Kılıç, T1
Ural, D1
Labos, C1
Dasgupta, K1
Nedjar, H1
Turecki, G1
Rahme, E1
Abegunewardene, N1
Schmidt, KH1
Vosseler, M1
Kreitner, KF1
Schreiber, LM1
Lehr, HA1
Gori, T1
Münzel, T1
Horstick, G1
Porto, I1
D'Amario, D1
Crea, F1
Stankovic, S1
Asanin, M1
Trifunovic, D1
Majkic-Singh, N1
Ignjatovic, S1
Mrdovic, I1
Matic, D1
Savic, L1
Marinkovic, J1
Vasiljevic, Z1
Hondo, T1
Matsumura, H1
Matsuda, K1
Iwamoto, A1
Eno, S1
Kimura, M1
Hess, CN1
Broderick, S1
Piccini, JP1
Alexander, KP1
Newby, LK1
Shaw, LK1
Mahaffey, KW1
Alexander, JH1
Peterson, ED1
Granger, CB1
Lopes, RD1
Han, YL1
Zhang, L1
Yang, LX1
Liu, HL1
Qu, P1
Li, WM1
Jiang, TM1
Li, SM1
Jing, QM1
Zhang, QY1
Xu, B1
Li, Y1
Gao, RL1
Turpie, AG1
Bahrmann, P1
Sigusch, HH1
Surber, R1
Figulla, HR1
Malinin, AI3
Dzhanashvili, AI1
Sane, DC3
Gerschutz, GP1
Bhatt, DL1
Kindsvater, S1
Leclerc, K1
Ward, J1
Fries, R1
Böhm, M1
Jessup, DB1
Coletti, AT1
Muhlestein, JB1
Barry, WH1
Shean, FC1
Whisenant, BK1
Jerome, SD1
Lowry, DR1
Morgan, AW1
Tanguay, JF1
Steinhubl, SR1
Califf, RM1
Packer, M1
Warren, S1
Garcia, S1
Canoniero, MJ1
Chirinos, JA1
de Marchena, E1
Salerno, T1
Ferreira, A1
Meune, C2
Mahé, I2
Solal, AC1
Lévy, BI1
Duboc, D2
Simoneau, G2
Champion, K1
Mourad, JJ1
Weber, S2
Bergmann, JF2
Verheugt, FW1
Grabowski, M1
Barg, W1
Biełous-Wilk, A1
Kopec, A1
Chmielowicz, B1
Panaszek, B1
Wahbi, K1
Fulla, Y1
Cohen-Solal, A1
Mouly, S1
de Silva, R1
Nikitin, NP1
Witte, KK1
Rigby, AS1
Loh, H1
Nicholson, A1
Bhandari, S1
Clark, AL1
Oshrine, BR1
Erdmann, E1
Recio-Mayoral, A1
Kaski, JC1
McMurray, JJ1
Horowitz, J1
van Veldhuisen, DJ1
Remme, WJ1
Kirsch, M1
Vermes, E1
Boval, B1
Drouet, L1
Loisance, D1
Ferguson, JJ1
Guazzi, M1
Horwich, TB1
Fonarow, GC1
Nuttall, A1
Smith, HJ1
Loveday, BE1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
STREAM (Strategic Reperfusion Early After Myocardial Infarction). Comparison of the Efficacy and Safety of a Strategy of Early Fibrinolytic Treatment With Tenecteplase and Additional Antiplatelet and Antithrombin Therapy Followed by Catheterisation Within[NCT00623623]Phase 31,899 participants (Actual)Interventional2008-03-01Completed
Analysis of the Platelet Activity State in Patients Implanted With Ventricular Assist Device (VAD)[NCT03255928]60 participants (Anticipated)Observational [Patient Registry]2017-06-29Recruiting
STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction[NCT02777580]Phase 4609 participants (Actual)Interventional2017-08-01Active, not recruiting
Dapagliflozin Effects on Mayor Adverse Cardiovascular Events in Patients With Acute Myocardial Infarction (DAPA-AMI). Randomized Clinical Trial[NCT04717986]188 participants (Actual)Interventional2021-01-26Completed
Reperfusion Strategies in ST Elevation Myocardial Infarction Network - Sao Paulo Registry.[NCT02090712]3,000 participants (Anticipated)Observational [Patient Registry]2010-01-31Enrolling by invitation
CSP #442 - Warfarin and Antiplatelet Therapy Study in Patients With Congestive Heart Failure (WATCH)[NCT00007683]Phase 31,587 participants (Anticipated)Interventional1998-10-31Completed
Comparative Study of Clinical Efficacy and Safety of Different Clopidogrel Salts in Patients With Cardiovascular Disease. A Multi-center Non-interventional Clinical Trial.[NCT02126982]1,500 participants (Actual)Observational2012-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Patients With All Cause Death and Non-fatal Stroke

This is a key secondary endpoint. The number of observed patients with all cause death and non-fatal stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)50
Primary PCI (Group B)43

Number of Patients With All Cause Death and Shock

This is a key secondary endpoint. The number of observed patients with all cause death and shock within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)59
Primary PCI (Group B)73

Number of Patients With All Cause Death and Shock and CHF

This is a key secondary endpoint. The number of observed patients with all cause death and shock and CHF within 30 days was reported. (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)100
Primary PCI (Group B)123

Number of Patients With All Cause Death and Shock and CHF and Reinfarction and Disabling Stroke

This is a key secondary endpoint. The number of observed patients with all cause death and shock and CHF and reinfarction and disabling stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)117
Primary PCI (Group B)135

Number of Patients With All Cause Death and Shock and Reinfarction

This is a key secondary endpoint. The number of observed patients with all cause death and shock and reinfarction within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)77
Primary PCI (Group B)85

Number of Patients With All Cause Mortality

This is a key secondary endpoint. The number of observed patients with all cause mortality within 30 days was reported. (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)43
Primary PCI (Group B)42

Number of Patients With All-cause Mortality, Cardiogenic Shock, Congestive Heart Failure and Recurrent Myocardial Infarction Within 30 Days for FAS.

The number of observed patients with all-cause mortality, cardiogenic shock, congestive heart failure (CHF) and recurrent myocardial infarction within 30 days was reported for full analysis set (FAS). (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)116
Primary PCI (Group B)135

Number of Patients With Cardiac Mortality

This is a key secondary endpoint. The number of observed patients with cardiac mortality within 30 days was reported. (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)31
Primary PCI (Group B)32

Number of Patients With Cardiogenic Shock

This is a key secondary endpoint. The number of observed patients with cardiogenic shock within 30 days was reported. (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)41
Primary PCI (Group B)56

Number of Patients With Congestive Heart Failure (CHF)

This is a key secondary endpoint. The number of observed patients with congestive heart failure (CHF) within 30 days was reported. (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)57
Primary PCI (Group B)72

Number of Patients With Intracranial Haemorrhage

This is a key secondary endpoint. The number of observed patients with intracranial haemorrhage within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)9
Primary PCI (Group B)2

Number of Patients With Ischaemic Stroke

This is a key secondary endpoint. The number of observed patients with ischaemic stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)6
Primary PCI (Group B)3

Number of Patients With Major Non-intracranial Bleeds Including Blood Transfusions

This is a key secondary endpoint. The number of observed patients with major non-intracranial bleeds including blood transfusions within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)61
Primary PCI (Group B)45

Number of Patients With Minor Non-intracranial Bleeds

This is a key secondary endpoint. The number of observed patients with minor non-intracranial bleeds within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)206
Primary PCI (Group B)191

Number of Patients With Recurrent Myocardial Infarction (Reinfarction)

This is a key secondary endpoint. The number of observed patients with recurrent myocardial infarction (reinfarction) within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)23
Primary PCI (Group B)21

Number of Patients With Rehospitalisation for Cardiac Reasons

This is a key secondary endpoint. The number of observed patients with rehospitalisation for cardiac reasons within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)45
Primary PCI (Group B)41

Number of Patients With Rehospitalisation for Non-cardiac Reasons

This is a key secondary endpoint. The number of observed patients with rehospitalisation for non-cardiac reasons within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)19
Primary PCI (Group B)11

Number of Patients With Serious Repeat Target Vessel Revascularization

This is a key secondary endpoint. The number of observed patients with serious repeat target vessel revascularization within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)1
Primary PCI (Group B)2

Number of Patients With Serious Resuscitated Ventricular Fibrillation

This is a key secondary endpoint. The number of observed patients with serious resuscitated ventricular fibrillation within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)32
Primary PCI (Group B)38

Number of Patients With Serious Resuscitated Ventricular Fibrillation in Association With Invasive Procedures

This is a key secondary endpoint. The number of observed patients with serious resuscitated ventricular fibrillation in association with invasive procedures (occurring at any time during catheterisation or urgent/elective PCI) within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)10
Primary PCI (Group B)29

Number of Patients With Total Disabling Stroke

This is a key secondary endpoint. The number of observed patients with total disabling stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)2
Primary PCI (Group B)0

Number of Patients With Total Fatal Stroke

This is a key secondary endpoint. The number of observed patients with total fatal stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)7
Primary PCI (Group B)4

Number of Patients With Total Non-disabling Stroke

This is a key secondary endpoint. The number of observed patients with total non-disabling stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)8
Primary PCI (Group B)1

Number of Patients With Total Non-intracranial Bleeds

This is a key secondary endpoint. The number of observed patients with total non-intracranial bleeds within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)267
Primary PCI (Group B)236

Number of Patients With Total Stroke (All Types)

This is a key secondary endpoint. The number of observed patients with total stroke (all types) within 30 days was reported (NCT00623623)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tenecteplase (Group A)15
Primary PCI (Group B)5

Reviews

6 reviews available for ticlopidine and Heart Failure

ArticleYear
Cilostazol and primary-PCI: mirage or good alternative?
    Current vascular pharmacology, 2012, Volume: 10, Issue:4

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arrhythmias, Cardiac; Aspirin; Cilostazol;

2012
State of the art--a journey through the world of antithrombotic therapy.
    Seminars in thrombosis and hemostasis, 2002, Volume: 28 Suppl 3

    Topics: Ambulatory Care; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Coronary Disease; Fibrinolytic A

2002
Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel?
    American heart journal, 2003, Volume: 145, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Thera

2003
[Update cardiology 2001/2002-part II. From unstable coronary syndrome to terminal heart failure].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Jun-15, Volume: 98, Issue:6

    Topics: Abciximab; Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Antibodies, Monoclonal; Ant

2003
[Cardiology 2007].
    Deutsche medizinische Wochenschrift (1946), 2007, Jun-22, Volume: 132, Issue:25-26

    Topics: Angioplasty, Balloon, Coronary; Cardiopulmonary Resuscitation; Cholesterol; Clopidogrel; Coronary Ar

2007
Prevention of heart failure.
    Current cardiology reports, 2002, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Ant

2002

Trials

12 trials available for ticlopidine and Heart Failure

ArticleYear
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction.
    The New England journal of medicine, 2013, Apr-11, Volume: 368, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination;

2013
Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: observations from the CLARITY-TIMI 28 trial.
    Clinical cardiology, 2014, Volume: 37, Issue:3

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Circulation; Coronary Thrombosis; Creatin

2014
Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure.
    Stroke, 2015, Volume: 46, Issue:3

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopid

2015
Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial.
    Circulation, 2009, Mar-31, Volume: 119, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chronic Disease; Clopidogrel; Death; Double-Blind Method; F

2009
Oral antiplatelet therapies have no effect on circulating levels of RANTES in patients with coronary artery disease.
    Die Pharmazie, 2002, Volume: 57, Issue:12

    Topics: Aged; Angina, Unstable; Chemokine CCL5; Chemokines; Clopidogrel; Coronary Artery Disease; Female; He

2002
The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study: to what extent should the results be generalizable?
    American heart journal, 2003, Volume: 145, Issue:4

    Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Heart Failure

2003
Effects of coadministration of aspirin or clopidogrel on exercise testing in patients with heart failure receiving angiotensin-converting enzyme inhibitors.
    The American journal of cardiology, 2003, Jun-01, Volume: 91, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Cros

2003
Effects of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: the Plavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) trial.
    American heart journal, 2003, Volume: 146, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Heart Failure; Humans

2003
Watching the WATCH trial: the role of sponsors and data monitoring committees.
    Journal of cardiac failure, 2004, Volume: 10, Issue:2

    Topics: Anticoagulants; Aspirin; Clinical Trials Data Monitoring Committees; Clopidogrel; Heart Failure; Hum

2004
The Warfarin and Antiplatelet Therapy in Heart Failure trial (WATCH): rationale, design, and baseline patient characteristics.
    Journal of cardiac failure, 2004, Volume: 10, Issue:2

    Topics: Adult; Aged; Anticoagulants; Aspirin; Clopidogrel; Embolism; Female; Heart Failure; Humans; Male; Mi

2004
Comparative effect of aspirin and clopidogrel on arterial function in CHF.
    International journal of cardiology, 2006, Jan-04, Volume: 106, Issue:1

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chi-Square Distribution; Clopidogrel; Doubl

2006
Effects of aspirin and clopidogrel on plasma brain natriuretic peptide in patients with heart failure receiving ACE inhibitors.
    European journal of heart failure, 2007, Volume: 9, Issue:2

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Aspirin; Clopidogrel; Female; Heart Fa

2007

Other Studies

41 other studies available for ticlopidine and Heart Failure

ArticleYear
Future of antithrombotic therapy for heart failure with coronary artery disease.
    European heart journal. Cardiovascular pharmacotherapy, 2022, 08-11, Volume: 8, Issue:5

    Topics: Clopidogrel; Coronary Artery Disease; Fibrinolytic Agents; Heart Failure; Humans; Ticlopidine

2022
Association of fractalkine with functional severity of heart failure and impact on clopidogrel efficacy in patients with ischemic heart disease.
    Thrombosis research, 2020, Volume: 196

    Topics: Blood Platelets; Chemokine CX3CL1; Clopidogrel; Coronary Artery Disease; Heart Failure; Humans; Plat

2020
Relationship Between Arterial Access and Outcomes in ST-Elevation Myocardial Infarction With a Pharmacoinvasive Versus Primary Percutaneous Coronary Intervention Strategy: Insights From the STrategic Reperfusion Early After Myocardial Infarction (STREAM)
    Journal of the American Heart Association, 2016, 06-13, Volume: 5, Issue:6

    Topics: Aged; Aspirin; Catheterization, Peripheral; Clopidogrel; Coronary Angiography; Enoxaparin; Female; F

2016
Which Antiplatelet Therapy in Patients With Left Ventricular Assist Device and Aspirin Allergy?
    The Annals of thoracic surgery, 2018, Volume: 105, Issue:2

    Topics: Aspirin; Clopidogrel; Drug Hypersensitivity; Drug Therapy, Combination; Heart Failure; Heart-Assist

2018
Left ventricular mural thrombus despite treatment with dabigatran and clopidogrel.
    BMJ case reports, 2018, May-30, Volume: 2018

    Topics: Aged, 80 and over; Anticoagulants; Antithrombins; Atrial Fibrillation; Clopidogrel; Dabigatran; Diag

2018
Fractalkine promotes platelet activation and vascular dysfunction in congestive heart failure.
    Thrombosis and haemostasis, 2014, Apr-01, Volume: 111, Issue:4

    Topics: Adenosine Diphosphate; Animals; Aorta; Cells, Cultured; Chemokine CX3CL1; Clopidogrel; CX3C Chemokin

2014
[Multination clinical trials: what is the relevance and what are the lessons from across-country differences?].
    Giornale italiano di cardiologia (2006), 2014, Volume: 15, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Americas; Benzazepines; Cardiovascular Agents; Cardiovascular Di

2014
Activated Hemostatic Biomarkers in Patients with Implanted Left Ventricle Assist Devices: Are Heparin and/or Clopidogrel Justified?
    Cardiology, 2015, Volume: 131, Issue:3

    Topics: Adult; Anticoagulants; Aspirin; Biomarkers; Clopidogrel; Drug Therapy, Combination; Fibrin Fibrinoge

2015
A population-based study of the drug interaction between clopidogrel and angiotensin converting enzyme inhibitors.
    British journal of clinical pharmacology, 2015, Volume: 80, Issue:4

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Case-Control Studies; Clopidogrel; Databases, Factua

2015
Antiplatelet therapy in Takotsubo cardiomyopathy: does it improve cardiovascular outcomes during index event?
    Heart and vessels, 2016, Volume: 31, Issue:8

    Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Heart Failure; Hospital Mortality; Hu

2016
Clinical Features and Outcomes of Diffuse Alveolar Hemorrhage During Antithrombotic Therapy: A Retrospective Cohort Study.
    Lung, 2016, Volume: 194, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Connective Tissue Diseases; Female

2016
Trends in antithrombotic therapy for atrial fibrillation: Data from the Veterans Health Administration Health System.
    American heart journal, 2016, Volume: 179

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Atrial Fibrillation; Clopidogrel; Dabigatran

2016
Resuscitation experience in a patient with left ventricular assist device.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Anesthesia, General; Anticoagulants; Capnography; Cardiopulmonary Resuscitation; Clopidogrel; Defibr

2016
Pump Thrombosis following HeartMate II Left Ventricular Assist Device Implantation in a Patient with Aspirin and Plavix Resistance.
    The heart surgery forum, 2016, 12-14, Volume: 19, Issue:6

    Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Heart Failure; Heart-Assist Devices; Humans; Male; Plat

2016
[Cardiology 2009].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:25-26

    Topics: Aryl Hydrocarbon Hydroxylases; Atrial Fibrillation; Cardiology; Cardiovascular Diseases; Clopidogrel

2009
Letter by Kan et al regarding Article, "randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart failure (WATCH) trial".
    Circulation, 2009, Nov-17, Volume: 120, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chronic Disease; Clopidogrel; Death; Double-Blind Method; F

2009
Increased mortality associated with low use of clopidogrel in patients with heart failure and acute myocardial infarction not undergoing percutaneous coronary intervention: a nationwide study.
    Journal of the American College of Cardiology, 2010, Mar-30, Volume: 55, Issue:13

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Denmark; Female; Heart Failure; Humans; Ma

2010
Clopidogrel and heart failure survival: missed opportunity or wrong turn?
    Journal of the American College of Cardiology, 2010, Mar-30, Volume: 55, Issue:13

    Topics: Clopidogrel; Denmark; Heart Failure; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors;

2010
Cardiorenal syndromes--recommendations from clinical practice guidelines: the cardiologist's view.
    Contributions to nephrology, 2010, Volume: 165

    Topics: Acute Disease; Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhib

2010
Antithrombotic therapies in patients with heart failure: hypothesis formulation from a research database.
    Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Cohor

2010
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure.
    Basic research in cardiology, 2011, Volume: 106, Issue:3

    Topics: Adenylyl Cyclases; Animals; Aorta; Blotting, Western; Clopidogrel; Endothelium, Vascular; Heart Fail

2011
Wireless pulmonary artery haemodynamic monitoring.
    Lancet (London, England), 2011, Jun-25, Volume: 377, Issue:9784

    Topics: Anticoagulants; Aspirin; Clopidogrel; Electrodes, Implanted; Equipment Design; Female; Heart Failure

2011
Comparison of characteristics, management practices, and outcomes of patients between the global registry and the gulf registry of acute coronary events.
    The American journal of cardiology, 2011, Nov-01, Volume: 108, Issue:9

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Aspiri

2011
Aspirin, clopidogrel, and warfarin use and outcomes in a cohort of 580 patients discharged after hospitalization for decompensated heart failure.
    Heart and vessels, 2012, Volume: 27, Issue:6

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Chi-Square Distribution; Ch

2012
Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Nov-08, Volume: 183, Issue:16

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Angioplasty; Anticoagulants; Antihypertensive Ag

2011
Gene therapy with iNOS enhances regional contractility and reduces delayed contrast enhancement in a model of postischemic congestive heart failure.
    Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4

    Topics: Animals; Anticoagulants; Aspirin; Clopidogrel; Contrast Media; Coronary Angiography; Coronary Stenos

2011
Time-dependent changes of myeloperoxidase in relation to in-hospital mortality in patients with the first anterior ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention.
    Clinical biochemistry, 2012, Volume: 45, Issue:7-8

    Topics: Aged; Angioplasty; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Chemical Analysis; Clo

2012
A case of acute coronary artery occlusion associated with very rapid onset heparin-induced thrombosis without thrombocytopenia.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:6

    Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Aspirin; Autoantibodies

2012
Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients.
    American heart journal, 2012, Volume: 164, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cor

2012
A new generation of biodegradable polymer-coated sirolimus-eluting stents for the treatment of coronary artery disease: final 5-year clinical outcomes from the CREATE study.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7

    Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; China; Clopidogrel; Coronary Artery Disea

2012
Elective coronary angiography and percutaneous coronary intervention during uninterrupted warfarin therapy.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2003, Volume: 60, Issue:2

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Atrial Fibrillation; Cardia

2003
Development of a score to predict the need for coronary artery bypass graft surgery in patients with non-ST segment elevation acute coronary syndromes.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:6

    Topics: Aged; Angina, Unstable; Clopidogrel; Coronary Artery Bypass; Heart Failure; Humans; Logistic Models;

2004
Antithrombotic therapy in heart failure.
    Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Clopidogrel; Drug Interactions; H

2006
[Transient pancytopenia due to ticlopidine--a case report].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Female; Fibrinolytic Agents; Heart Failure; Humans; Pancytopenia; Pneum

2005
Effects of applying a standardised management algorithm for moderate to severe renal dysfunction in patients with chronic stable heart failure.
    European journal of heart failure, 2007, Volume: 9, Issue:4

    Topics: Aged; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Creatinine; Female

2007
Does heart failure etiology, New York Heart Association class, or ejection fraction affect the ability of clopidogrel to inhibit heightened platelet activity?
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Drug Evaluation; Female; Heart Failure; H

2007
Clinical trials update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY.
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:6

    Topics: Abciximab; Acute Coronary Syndrome; Amides; Antibodies, Monoclonal; Benzazepines; Clinical Trials as

2007
[Four years of circulatory support with the INCOR axial pump from Berlin Heart].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100, Issue:11

    Topics: Clopidogrel; Coronary Thrombosis; Enoxaparin; Fibrinolytic Agents; Heart Failure; Heart-Assist Devic

2007
Meeting highlights. Highlights of the 48th scientific sessions of the American College of Cardiology.
    Circulation, 1999, Aug-10, Volume: 100, Issue:6

    Topics: Abciximab; Alanine; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibo

1999
Hemodynamic interaction of aspirin with enalapril.
    Circulation, 1999, Dec-21, Volume: 100, Issue:25

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Enalapril; Heart Failure; Hemodynamics; Humans; P

1999
A clinically relevant model of heart failure: effects of ticlopidine.
    Cardiovascular research, 1985, Volume: 19, Issue:4

    Topics: Animals; Blood Pressure; Coronary Circulation; Disease Models, Animal; Embolism; Female; Heart Failu

1985