ticlopidine has been researched along with Endotoxemia in 2 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of clopidogrel on clinical and clinicopathologic variables in healthy horses with experimentally induced endotoxemia." | 9.19 | Effects of clopidogrel on horses with experimentally induced endotoxemia. ( Brooks, MB; Cummings, KJ; Divers, TJ; Frye, AH; Fubini, SL; Ness, SL; Stokol, T; Watts, AE, 2014) |
| "To evaluate the effects of clopidogrel on clinical and clinicopathologic variables in healthy horses with experimentally induced endotoxemia." | 5.19 | Effects of clopidogrel on horses with experimentally induced endotoxemia. ( Brooks, MB; Cummings, KJ; Divers, TJ; Frye, AH; Fubini, SL; Ness, SL; Stokol, T; Watts, AE, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiers, D | 1 |
| van der Heijden, WA | 1 |
| van Ede, L | 1 |
| Gerretsen, J | 1 |
| de Mast, Q | 1 |
| van der Ven, AJ | 1 |
| El Messaoudi, S | 1 |
| Rongen, GA | 1 |
| Gomes, M | 1 |
| Kox, M | 1 |
| Pickkers, P | 1 |
| Riksen, NP | 1 |
| Watts, AE | 1 |
| Ness, SL | 1 |
| Divers, TJ | 1 |
| Fubini, SL | 1 |
| Frye, AH | 1 |
| Stokol, T | 1 |
| Cummings, KJ | 1 |
| Brooks, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin[NCT03869268] | Phase 4 | 72 participants (Actual) | Interventional | 2019-04-24 | Completed | ||
| Characterisation of a Novel Regimen of Very Low-dose Aspirin Combined With Rivaroxaban in Patients With Chronic Coronary Syndromes: WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?[NCT04990791] | Phase 4 | 48 participants (Anticipated) | Interventional | 2021-08-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ticlopidine and Endotoxemia
| Article | Year |
|---|---|
A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.
Topics: Adenosine; Administration, Intravenous; Adolescent; Adult; Aspirin; Cells, Cultured; Clopidogrel; Cy | 2017 |
A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.
Topics: Adenosine; Administration, Intravenous; Adolescent; Adult; Aspirin; Cells, Cultured; Clopidogrel; Cy | 2017 |
A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.
Topics: Adenosine; Administration, Intravenous; Adolescent; Adult; Aspirin; Cells, Cultured; Clopidogrel; Cy | 2017 |
A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.
Topics: Adenosine; Administration, Intravenous; Adolescent; Adult; Aspirin; Cells, Cultured; Clopidogrel; Cy | 2017 |
Effects of clopidogrel on horses with experimentally induced endotoxemia.
Topics: Analysis of Variance; Animals; Body Temperature; Clopidogrel; Endotoxemia; Female; Fibrinogen; Flow | 2014 |