Page last updated: 2024-11-05

ticlopidine and Dyspepsia

ticlopidine has been researched along with Dyspepsia in 4 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Dyspepsia: Impaired digestion, especially after eating.

Research Excerpts

ExcerptRelevanceReference
"To assess the impact of prophylactic omeprazole with background dual anti-platelet therapy on patient-reported symptoms of dyspepsia compared to placebo."9.20The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M, 2015)
"To assess the impact of prophylactic omeprazole with background dual anti-platelet therapy on patient-reported symptoms of dyspepsia compared to placebo."5.20The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M, 2015)
"Randomized patients with available aspirin dosing information in COGENT (N = 3,752) were divided into "low-dose" (≤ 100 mg) and "high-dose" (>100 mg) aspirin groups."2.82Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Hsieh, WH; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; Schnitzer, TJ; Shook, TL; Vaduganathan, M, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vardi, M1
Cryer, BL2
Cohen, M2
Lanas, A2
Schnitzer, TJ2
Lapuerta, P2
Goldsmith, MA2
Laine, L2
Doros, G2
Liu, Y2
McIntosh, AI1
Cannon, CP2
Bhatt, DL2
Vaduganathan, M1
Hsieh, WH1
Shook, TL1
Jones, L1
Griffin, S1
Palmer, S1
Main, C1
Orton, V1
Sculpher, M1
Sudlow, C1
Henderson, R1
Hawkins, N1
Riemsma, R1
Stiefelhagen, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease[NCT00557921]Phase 35,000 participants (Anticipated)Interventional2007-12-31Terminated (stopped due to Terminated by Sponsor)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ticlopidine and Dyspepsia

ArticleYear
Clinical effectiveness and cost-effectiveness of clopidogrel and modified-release dipyridamole in the secondary prevention of occlusive vascular events: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2004, Volume: 8, Issue:38

    Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Delayed-Action Preparations; Diarrhea; Dipyridamole; Dr

2004

Trials

2 trials available for ticlopidine and Dyspepsia

ArticleYear
The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug The

2015
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
    Journal of the American College of Cardiology, 2016, Apr-12, Volume: 67, Issue:14

    Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia;

2016

Other Studies

1 other study available for ticlopidine and Dyspepsia

ArticleYear
[Gastroenterology in family practice. Updates for your "stomach patient"].
    MMW Fortschritte der Medizin, 2006, Jun-01, Volume: 148, Issue:22

    Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Dyspepsia; Esophagitis, Peptic; Family Practice; Heartburn;

2006