ticlopidine has been researched along with Diarrhea in 27 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of 72 children with diarrhea associated hemolytic uremic syndrome, 88% were treated with platelet aggregation inhibitors (clopidogrel 56%, sulfinpyrazone 19%, dipyridamole 13%)." | 9.16 | Efficacy and safety of clopidogrel in children with diarrhea associated hemolytic uremic syndrome. ( Bakel, LA; Cadnapaphornchai, MA; Ford, D; Gao, D; Lum, G; Seltz, LB; Tiehen, J, 2012) |
| "The Ticlopidine Microangiopathy of Diabetes study (TIMAD), a randomized, double-masked, placebo-controlled trial, assessed the effect of this antiplatelet agent (ticlopidine hydrochloride) in reducing the progression of nonproliferative diabetic retinopathy in 435 patients followed up for 3 years." | 9.06 | Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group. ( , 1990) |
| "To describe ticlopidine related microscopic colitis and to assess the occurrence of apoptosis in the colon epithelium." | 7.70 | Ticlopidine induced colitis: a histopathological study including apoptosis. ( Berrebi, D; Dauge, MC; Flejou, JF; Peuchmaur, M; Potet, F; Sautet, A, 1998) |
| "Lymphocytic colitis is a chronic inflammatory colonic disease characterized by watery diarrhea and a dense infiltration of the colonic mucosa with lymphocytes." | 6.40 | Lymphocytic colitis, induced by ticlopidine. ( Bartz, KO; Feurle, GE; Schmitt-Gräff, A, 1999) |
| "Lymphocytic colitis is a clinico-pathological syndrome characterized by chronic diarrhea, normal endoscopy, diffuse colonic mucosal inflammatory changes." | 5.30 | [Ticlopidine-induced lymphocytic colitis]. ( Abd Alsamad, I; Chousterman, M; Cohen, C; Fléjou, JF; Hagege, H; Nahon, S; Rosa, I, 1999) |
| "Of 72 children with diarrhea associated hemolytic uremic syndrome, 88% were treated with platelet aggregation inhibitors (clopidogrel 56%, sulfinpyrazone 19%, dipyridamole 13%)." | 5.16 | Efficacy and safety of clopidogrel in children with diarrhea associated hemolytic uremic syndrome. ( Bakel, LA; Cadnapaphornchai, MA; Ford, D; Gao, D; Lum, G; Seltz, LB; Tiehen, J, 2012) |
| " Furthermore, the simpler dosing regimen, the absence of neutropenia, and the lower frequency of other side effects make it a safe alternative to ticlopidine." | 5.09 | Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation. ( Collins, M; Colombo, A; Iyer, S; Kreps, E; Maida, R; Moses, JW; Moussa, I; Oetgen, M; Roubin, G; Wang, X, 1999) |
| "The Ticlopidine Microangiopathy of Diabetes study (TIMAD), a randomized, double-masked, placebo-controlled trial, assessed the effect of this antiplatelet agent (ticlopidine hydrochloride) in reducing the progression of nonproliferative diabetic retinopathy in 435 patients followed up for 3 years." | 5.06 | Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group. ( , 1990) |
| "To describe ticlopidine related microscopic colitis and to assess the occurrence of apoptosis in the colon epithelium." | 3.70 | Ticlopidine induced colitis: a histopathological study including apoptosis. ( Berrebi, D; Dauge, MC; Flejou, JF; Peuchmaur, M; Potet, F; Sautet, A, 1998) |
| "Ticlopidine has not been formally compared with aspirin in patients with a completed stroke." | 2.67 | Ticlopidine versus aspirin for the prevention of recurrent stroke. Analysis of patients with minor stroke from the Ticlopidine Aspirin Stroke Study. ( Harbison, JW, 1992) |
| " Proton pump inhibitors cause few adverse effects with short-term use; however, long-term use has been scrutinized for appropriateness, drug-drug interactions, and the potential for adverse effects (e." | 2.48 | Reducing adverse effects of proton pump inhibitors. ( Ament, PW; Dicola, DB; James, ME, 2012) |
| "Lymphocytic colitis is a chronic inflammatory colonic disease characterized by watery diarrhea and a dense infiltration of the colonic mucosa with lymphocytes." | 2.40 | Lymphocytic colitis, induced by ticlopidine. ( Bartz, KO; Feurle, GE; Schmitt-Gräff, A, 1999) |
| "Ticlopidine is a potent inhibitor of platelet aggregation whose mechanism of action remains unknown." | 2.38 | [Severe diarrhea caused by Ticlid associated with disorders of small intestine motility]. ( Bruna, T; Colin, R; Denis, P; Ducrotté, P; Guédon, C; Lerebours, E, 1989) |
| "Lymphocytic colitis is a clinico-pathological syndrome characterized by chronic diarrhea, normal endoscopy, diffuse colonic mucosal inflammatory changes." | 1.30 | [Ticlopidine-induced lymphocytic colitis]. ( Abd Alsamad, I; Chousterman, M; Cohen, C; Fléjou, JF; Hagege, H; Nahon, S; Rosa, I, 1999) |
| "Ticlopidine was administered by gavage at a dose of 50 mg/kg/day starting 72 hr prior to hemodialysis and continuing throughout the period of hemodialysis (4 days)." | 1.26 | A comparison of ticlopidine and heparin on hemodialysis in dogs. ( Bush, H; Flamenbaum, W; Gross, ML; Hamburger, RJ; Weinger, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (18.52) | 18.7374 |
| 1990's | 16 (59.26) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soghomonyan, S | 1 |
| Abdel-Rasoul, M | 1 |
| Zuleta-Alarcon, A | 1 |
| Grants, I | 1 |
| Davila, V | 1 |
| Yu, J | 1 |
| Zhang, C | 1 |
| Whitaker, EE | 1 |
| Bergese, SD | 1 |
| Stoicea, N | 1 |
| Arsenescu, R | 1 |
| Christofi, FL | 1 |
| Seltz, LB | 1 |
| Bakel, LA | 1 |
| Tiehen, J | 1 |
| Gao, D | 1 |
| Cadnapaphornchai, MA | 1 |
| Lum, G | 1 |
| Ford, D | 1 |
| Ament, PW | 1 |
| Dicola, DB | 1 |
| James, ME | 1 |
| Jones, L | 1 |
| Griffin, S | 1 |
| Palmer, S | 1 |
| Main, C | 1 |
| Orton, V | 1 |
| Sculpher, M | 1 |
| Sudlow, C | 1 |
| Henderson, R | 1 |
| Hawkins, N | 1 |
| Riemsma, R | 1 |
| Giardina, MG | 1 |
| Matarazzo, M | 1 |
| Cacciatore, L | 1 |
| De Marco, F | 1 |
| Goyan, JE | 1 |
| Gross, ML | 1 |
| Bush, H | 1 |
| Weinger, R | 1 |
| Hamburger, RJ | 1 |
| Flamenbaum, W | 1 |
| Hoffman, HS | 1 |
| Butensky, MS | 1 |
| Valdés Oliveras, M | 1 |
| Barenys de Lacha, M | 1 |
| Abad Lacruz, A | 1 |
| Admetlla Falgueras, M | 1 |
| Fraga, MD | 1 |
| García, B | 1 |
| Agud, JL | 1 |
| Marco, J | 1 |
| de Juana, P | 1 |
| Cervero, M | 1 |
| Schmeck-Lindenau, HJ | 1 |
| Kurtz, W | 1 |
| Heine, M | 1 |
| Berrebi, D | 1 |
| Sautet, A | 1 |
| Flejou, JF | 2 |
| Dauge, MC | 1 |
| Peuchmaur, M | 1 |
| Potet, F | 1 |
| Brigot, C | 1 |
| Courillon-Mallet, A | 1 |
| Roucayrol, AM | 1 |
| Cattan, D | 1 |
| Swine, C | 1 |
| Cornette, P | 1 |
| Van Pee, D | 1 |
| Delos, M | 1 |
| Melange, M | 1 |
| Bouvet, C | 1 |
| Bellaiche, G | 1 |
| Slama, R | 1 |
| Auberger, E | 1 |
| Lachgar, T | 1 |
| Nury, B | 1 |
| Roche-Sicot, J | 1 |
| Moussa, I | 1 |
| Oetgen, M | 1 |
| Roubin, G | 1 |
| Colombo, A | 1 |
| Wang, X | 1 |
| Iyer, S | 1 |
| Maida, R | 1 |
| Collins, M | 1 |
| Kreps, E | 1 |
| Moses, JW | 1 |
| Rosa, I | 1 |
| Nahon, S | 1 |
| Cohen, C | 1 |
| Abd Alsamad, I | 1 |
| Hagege, H | 1 |
| Chousterman, M | 1 |
| Feurle, GE | 1 |
| Bartz, KO | 1 |
| Schmitt-Gräff, A | 1 |
| Borrás-Blasco, J | 1 |
| Navarro-Ruiz, A | 1 |
| Gutiérrez-Casbas, A | 1 |
| Matarredona-Catalá, J | 1 |
| González-Delgado, M | 1 |
| Harbison, JW | 1 |
| Rota Roca, MR | 1 |
| Castellote, J | 1 |
| Xiol, X | 1 |
| Sánchez Gili, M | 1 |
| Ruget, O | 1 |
| Burtin, P | 1 |
| Cérez, H | 1 |
| Calès, P | 1 |
| Boyer, J | 1 |
| Haynes, RB | 1 |
| Sandler, RS | 1 |
| Larson, EB | 1 |
| Pater, JL | 1 |
| Yatsu, FM | 1 |
| Chassany, O | 1 |
| Bacq, Y | 1 |
| Metman, EH | 1 |
| Gillion, JM | 1 |
| Dorval, ED | 1 |
| Jankowski, JM | 1 |
| Guédon, C | 1 |
| Bruna, T | 1 |
| Ducrotté, P | 1 |
| Lerebours, E | 1 |
| Denis, P | 1 |
| Colin, R | 1 |
4 reviews available for ticlopidine and Diarrhea
| Article | Year |
|---|---|
Reducing adverse effects of proton pump inhibitors.
Topics: Anemia, Iron-Deficiency; Clopidogrel; Clostridioides difficile; Critical Care; Diarrhea; Drug Intera | 2012 |
Clinical effectiveness and cost-effectiveness of clopidogrel and modified-release dipyridamole in the secondary prevention of occlusive vascular events: a systematic review and economic evaluation.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Delayed-Action Preparations; Diarrhea; Dipyridamole; Dr | 2004 |
Lymphocytic colitis, induced by ticlopidine.
Topics: Biopsy; Chronic Disease; Colitis; Colon; Colonoscopy; Diarrhea; Humans; Intestinal Mucosa; Lymphocyt | 1999 |
[Severe diarrhea caused by Ticlid associated with disorders of small intestine motility].
Topics: Aged; Aged, 80 and over; Diarrhea; Female; Gastrointestinal Motility; Humans; Intestine, Small; Male | 1989 |
4 trials available for ticlopidine and Diarrhea
| Article | Year |
|---|---|
Efficacy and safety of clopidogrel in children with diarrhea associated hemolytic uremic syndrome.
Topics: Adolescent; Child; Child, Preschool; Clopidogrel; Diarrhea; Female; Hemolytic-Uremic Syndrome; Human | 2012 |
Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Diarrhea; D | 1999 |
Ticlopidine versus aspirin for the prevention of recurrent stroke. Analysis of patients with minor stroke from the Ticlopidine Aspirin Stroke Study.
Topics: Adult; Aspirin; Cerebrovascular Disorders; Diarrhea; Double-Blind Method; Female; Humans; Male; Midd | 1992 |
Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group.
Topics: Adolescent; Adult; Aged; Diabetic Angiopathies; Diabetic Retinopathy; Diarrhea; Double-Blind Method; | 1990 |
19 other studies available for ticlopidine and Diarrhea
| Article | Year |
|---|---|
Clopidogrel IBS Patients Have Higher Incidence of Gastrointestinal Symptoms Influenced by Age and Gender.
Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Aged; Clopidogrel; Constipation; Databases, Factual; | 2017 |
Side effects of proton pump inhibitors.
Topics: Clopidogrel; Diarrhea; Drug Interactions; Gastroesophageal Reflux; Hip Fractures; Humans; Platelet A | 2012 |
Ticlopidine can cause chronic diarrhoea.
Topics: Aged; Anticoagulants; Chronic Disease; Diarrhea; Humans; Male; Thiophenes; Ticlopidine | 1984 |
Ticlopidine: quo vadis? Adverse reactions in man.
Topics: Anticoagulants; Aspirin; Diarrhea; Humans; Neutropenia; Product Surveillance, Postmarketing; Thiophe | 1984 |
A comparison of ticlopidine and heparin on hemodialysis in dogs.
Topics: Animals; Anorexia; Diarrhea; Dogs; Heparin; Renal Dialysis; Thiophenes; Ticlopidine; Uremia | 1982 |
Severe diarrhea with Ticlid therapy.
Topics: Aged; Chronic Disease; Diarrhea; Female; Humans; Severity of Illness Index; Ticlopidine | 1994 |
[Chronic diarrhea caused by ticlopidine].
Topics: Aged; Chronic Disease; Diarrhea; Female; Humans; Ticlopidine | 1993 |
Severe chronic diarrhea induced by ticlopidine.
Topics: Aged; Chronic Disease; Diarrhea; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 1996 |
[Lymphocytic colitis during ticlopidine therapy].
Topics: Aged; Colitis; Diarrhea; Female; Humans; Lymphocytes; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Ticlopidine induced colitis: a histopathological study including apoptosis.
Topics: Aged; Apoptosis; Chronic Disease; Colitis; Diarrhea; DNA Nucleotidylexotransferase; Female; Humans; | 1998 |
[Lymphocytic colitis and ticlopidine].
Topics: Adrenergic alpha-Antagonists; Aged; Captopril; Colitis; Diarrhea; Female; Humans; Hypertension; Isch | 1998 |
[Ticlopidine, diarrhea and lymphocytic colitis].
Topics: Aged; Aged, 80 and over; Colitis; Diabetes Complications; Diabetes Mellitus; Diarrhea; Female; Human | 1998 |
[Lymphocytic colitis and villous atrophy after treatment with ticlopidine].
Topics: Aged; Aged, 80 and over; Arteritis; Atrophy; Chronic Disease; Colitis; Diarrhea; Duodenum; Female; F | 1998 |
[Ticlopidine-induced lymphocytic colitis].
Topics: Aged; Biopsy; Chronic Disease; Colitis; Colon; Diarrhea; Fibrinolytic Agents; Humans; Male; Platelet | 1999 |
Multiple fixed-drug eruption and diarrhea with ticlopidine.
Topics: Diarrhea; Drug Eruptions; Humans; Male; Middle Aged; Stroke; Ticlopidine | 2002 |
[Severe chronic diarrhea caused by ticlopidine].
Topics: Cerebrovascular Disorders; Chronic Disease; Diarrhea; Humans; Male; Middle Aged; Ticlopidine | 1992 |
[Chronic diarrhea associated with villous atrophy and lymphocytic gastritis, caused by ticlopidine].
Topics: Aged; Atrophy; Chronic Disease; Diarrhea; Duodenum; Gastritis; Humans; Male; Ticlopidine | 1992 |
A critical appraisal of ticlopidine, a new antiplatelet agent. Effectiveness and clinical indications for prophylaxis of atherosclerotic events.
Topics: Arteriosclerosis; Cerebrovascular Disorders; Diarrhea; Female; Humans; Male; Neutropenia; Randomized | 1992 |
[Severe chronic diarrhea during treatment with ticlopidine].
Topics: Aged; Chronic Disease; Diarrhea; Humans; Male; Ticlopidine | 1989 |