ticlopidine has been researched along with Diabetic Retinopathy in 11 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Ticlopidine Microangiopathy of Diabetes study (TIMAD), a randomized, double-masked, placebo-controlled trial, assessed the effect of this antiplatelet agent (ticlopidine hydrochloride) in reducing the progression of nonproliferative diabetic retinopathy in 435 patients followed up for 3 years." | 9.06 | Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group. ( , 1990) |
| "The Ticlopidine Microangiopathy of Diabetes study (TIMAD), a randomized, double-masked, placebo-controlled trial, assessed the effect of this antiplatelet agent (ticlopidine hydrochloride) in reducing the progression of nonproliferative diabetic retinopathy in 435 patients followed up for 3 years." | 5.06 | Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group. ( , 1990) |
| "Ticlopidine, a thienopyridine that prevents the progression of diabetic retinopathy in humans, was recently shown to increase nitric oxide (NO) production in human neutrophils." | 3.72 | Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. ( Arrebola, M; De La Cruz, P; de la Cuesta, FS; González-Correa, A; Martinez-Cerdán, E; Moreno, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, JS | 1 |
| Mahmoud, TH | 1 |
| De La Cruz, P | 1 |
| Arrebola, M | 1 |
| González-Correa, A | 1 |
| Martinez-Cerdán, E | 1 |
| Moreno, A | 1 |
| de la Cuesta, FS | 1 |
| Sun, W | 1 |
| Gerhardinger, C | 1 |
| Dagher, Z | 1 |
| Hoehn, T | 1 |
| Lorenzi, M | 1 |
| Mirouze, J | 1 |
| Fujie, K | 1 |
| Fujie, Y | 1 |
| Rubtsova, AL | 1 |
| Ametov, AS | 1 |
| Strakhov, VV | 1 |
| Smolenskiĭ, VS | 1 |
| Bokarev, IN | 2 |
| Velikov, VK | 2 |
| Zelenchuk, NM | 2 |
| Frolova, AI | 1 |
| Iarovaia, LD | 1 |
| Polunin, GS | 1 |
4 trials available for ticlopidine and Diabetic Retinopathy
| Article | Year |
|---|---|
Ticlopidine in the secondary prevention of early diabetes-related microangiopathy: protocol of a multicenter therapeutic study (TIMAD study).
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Anticoagulants; Brain Ischemia; Clinical Trials as T | 1984 |
[The use of ticlid in diabetic retinopathy].
Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Humans; Insulin; Male; M | 1997 |
Clinical study of ticlopidine in diabetic retinopathy. Belgian Ticlopidine Retinopathy Study Group (BTRS).
Topics: Adolescent; Adult; Aged; Diabetic Retinopathy; Double-Blind Method; Drug Tolerance; Female; Fluoresc | 1992 |
Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group.
Topics: Adolescent; Adult; Aged; Diabetic Angiopathies; Diabetic Retinopathy; Diarrhea; Double-Blind Method; | 1990 |
7 other studies available for ticlopidine and Diabetic Retinopathy
| Article | Year |
|---|---|
Recommendations on the Clinical Use of Compound Danshen Dripping Pills.
Topics: Angina Pectoris; Aspirin; Camphanes; Clopidogrel; Coronary Disease; Diabetes Mellitus; Diabetic Neph | 2017 |
Anticoagulation and clinically significant postoperative vitreous hemorrhage in diabetic vitrectomy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Diabetic Retinopathy; Female; Humans; Incidence; Intraoperativ | 2011 |
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Clopidogrel; Diabetes Mellitus, Experim | 2003 |
Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; | 2005 |
[Effects of ticlopidine on blood circulation and thrombin-induced platelet aggregation in experimental diabetic rats- and it's efficacy for remedy of diabetic retinopathy (author's transl)].
Topics: Animals; Blood Circulation; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Platelet Ag | 1981 |
[Effect of ticlopidine on the course of diabetic microangiopathy].
Topics: Adult; Conjunctiva; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fema | 1988 |
[Effect of ticlopidine on hemostasis in patients with diabetic microangiopathy].
Topics: Adolescent; Adult; Diabetes Complications; Diabetic Retinopathy; Female; Hemostasis; Humans; Male; M | 1988 |