Page last updated: 2024-11-05

ticlopidine and Diabetic Nephropathies

ticlopidine has been researched along with Diabetic Nephropathies in 8 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We sought to assess the impact of renal function on platelet reactivity in patients with diabetes mellitus (DM) and coronary artery disease on aspirin and clopidogrel therapy."3.76Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy. ( Alfonso, F; Angiolillo, DJ; Bass, TA; Bernardo, E; Capodanno, D; Fernandez-Ortiz, A; Ferreiro, JL; Jimenez-Quevedo, P; Macaya, C; Sabaté, M; Ueno, M; Vivas, D, 2010)
"We present a case report of thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) developing in a kidney/pancreas transplant recipient after the initiation of treatment with clopidogrel for symptomatic coronary artery disease."1.31Clopidogrel-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in a kidney/pancreas transplant recipient. ( Chinnakotla, S; Fidler, ME; Hammeke, MD; Leone, JP; Tarantolo, S, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozyalvacli, ME1
Uyeturk, U1
Halicioglu, S1
Kargı, E1
Dasgupta, A1
Steinhubl, SR1
Bhatt, DL1
Berger, PB1
Shao, M1
Mak, KH1
Fox, KA1
Montalescot, G1
Weber, MA1
Haffner, SM1
Dimas, AP1
Steg, PG1
Topol, EJ1
Angiolillo, DJ1
Bernardo, E1
Capodanno, D1
Vivas, D1
Sabaté, M1
Ferreiro, JL1
Ueno, M1
Jimenez-Quevedo, P1
Alfonso, F1
Bass, TA1
Macaya, C1
Fernandez-Ortiz, A1
Igaki, N1
Matsuda, T1
Yatani, H1
Kawaguchi, T1
Kida, A1
Yanase, K1
Moriguchi, R1
Sakai, M1
Tamada, F1
Goto, T1
Nyberg, G1
Larsson, O1
Westberg, NG1
Aurell, M1
Jagenburg, R1
Blohmé, G1
Chinnakotla, S1
Leone, JP1
Fidler, ME1
Hammeke, MD1
Tarantolo, S1
Lang, J1
Cao, H1
Wei, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pragmatic Randomized Controlled Trial Comparing Treatment Effectiveness of Guideline Indicated Anti-platelet Therapy for Acute Coronary Syndrome in Patients With Chronic Kidney Disease[NCT03150667]Phase 4220 participants (Anticipated)Interventional2017-04-10Recruiting
Platelet Reactivity in Patients With Chronic Kidney Disease Receiving Adjunctive Cilostazol Compared to a High-maintenance Dose of Clopidogrel[NCT01328470]Phase 485 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for ticlopidine and Diabetic Nephropathies

ArticleYear
Clinical outcomes of patients with diabetic nephropathy randomized to clopidogrel plus aspirin versus aspirin alone (a post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance [CHARISMA] tri
    The American journal of cardiology, 2009, May-15, Volume: 103, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Diabetic Nephropathies; Drug

2009
[Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1998, Volume: 18, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Diabetic Nephropathies; Drugs, Chinese Herbal; Female; Ginsenos

1998

Other Studies

6 other studies available for ticlopidine and Diabetic Nephropathies

ArticleYear
Recommendations on the Clinical Use of Compound Danshen Dripping Pills.
    Chinese medical journal, 2017, Apr-20, Volume: 130, Issue:8

    Topics: Angina Pectoris; Aspirin; Camphanes; Clopidogrel; Coronary Disease; Diabetes Mellitus; Diabetic Neph

2017
Spontaneous renal parenchymal hematoma associated with clopidogrel in a patient with diabetic nephropathy.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:2

    Topics: Aged; Clopidogrel; Diabetic Nephropathies; Hematoma; Humans; Kidney Diseases; Male; Platelet Aggrega

2015
Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy.
    Journal of the American College of Cardiology, 2010, Mar-16, Volume: 55, Issue:11

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Diabe

2010
Deep venous thrombosis, myocardial infarction, and occlusion of vascular access associated with heparin-induced thrombocytopenia in a diabetic hemodialysis patient.
    Clinical and experimental nephrology, 2003, Volume: 7, Issue:4

    Topics: Anticoagulants; Catheters, Indwelling; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fi

2003
A platelet aggregation inhibitor--ticlopidine--in diabetic nephropathy: a randomized double blind study.
    Clinical nephrology, 1984, Volume: 21, Issue:3

    Topics: Adult; Creatinine; Diabetic Nephropathies; Double-Blind Method; Drug Evaluation; Female; Glomerular

1984
Clopidogrel-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in a kidney/pancreas transplant recipient.
    Transplantation, 2000, Aug-15, Volume: 70, Issue:3

    Topics: Adult; Clopidogrel; Coronary Disease; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathie

2000