ticlopidine and Complications of Diabetes Mellitus
ticlopidine has been researched along with Complications of Diabetes Mellitus in 66 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of dual antiplatelet therapy with aspirin and clopidogrel on the progression of native coronary artery disease after coronary artery bypass grafting are unknown." | 7.80 | Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial. ( Al-Atassi, T; Kulik, A; Le May, M; Ruel, M; Une, D; Voisine, P, 2014) |
| "Clopidogrel has been widely used to prevent recurrent ischemia in patients with acute coronary syndrome (ACS)." | 7.77 | Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome. ( Chung, HS; Han, JY; Kim, HJ; Kim, SR; Lee, SY; Park, KJ, 2011) |
| "635 Non ST Elevation Acute Coronary Syndrome (NSTE ACS) patients were included and received loading doses of 250 mg aspirin and 600 mg clopidogrel." | 7.75 | Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response. ( Alessi, MC; Bali, L; Bonnet, JL; Camoin, L; Cuisset, T; Frere, C; Juhan-Vague, I; Lambert, M; Morange, PE; Quilici, J, 2009) |
| "We evaluated the prevalence and mechanism of poor responsiveness to clopidogrel and prasugrel in coronary artery disease patients with and without diabetes." | 5.13 | Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. ( Brandt, JT; Braun, OO; Erlinge, D; Jakubowski, JA; James, S; Siegbahn, A; Sugidachi, A; Varenhorst, C; Wallentin, L; Winters, KJ, 2008) |
| "This study (Intracoronary Stenting and Antithrombotic Regimen: Is Abciximab a Superior Way to Eliminate Elevated Thrombotic Risk in Diabetics [ISAR-SWEET] Study) enrolled 701 diabetic patients with coronary artery disease who underwent an elective percutaneous coronary intervention after pretreatment with a 600-mg dose of clopidogrel >2 hours before the procedure: 351 patients were randomly assigned to abciximab and 350 patients to placebo." | 5.11 | Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel. ( Berger, PP; Bollwein, H; Dibra, A; Dirschinger, J; Dotzer, F; Kastrati, A; Mehilli, J; Pache, J; Schömig, A; Schühlen, H; von Beckerath, N, 2004) |
| " Platelet dysfunction has been implicated as a central contributor to the increased risk of coronary artery disease in patients with DM, and it is not surprising that the anti-platelet agent, clopidogrel, has been shown to have efficacy in both short and long term outcomes in patients with acute coronary syndrome and those undergoing percutaneous coronary intervention." | 4.87 | Variability of clopidogrel response in patients with type 2 diabetes mellitus. ( Banerjee, S; Hall, HM; McGuire, DK, 2011) |
| "A 62-year-old woman with hypertension, type 2 diabetes mellitus, hyperlipemia and coronary heart disease started taking clopidogrel, with no addition of any other new drugs." | 3.80 | Acquired pure red cell aplasia due to treatment with clopidogrel: first case report. ( Li, G; Li, ZQ; Yang, JD; Yang, QY, 2014) |
| "The effects of dual antiplatelet therapy with aspirin and clopidogrel on the progression of native coronary artery disease after coronary artery bypass grafting are unknown." | 3.80 | Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial. ( Al-Atassi, T; Kulik, A; Le May, M; Ruel, M; Une, D; Voisine, P, 2014) |
| "Clopidogrel has been widely used to prevent recurrent ischemia in patients with acute coronary syndrome (ACS)." | 3.77 | Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome. ( Chung, HS; Han, JY; Kim, HJ; Kim, SR; Lee, SY; Park, KJ, 2011) |
| "635 Non ST Elevation Acute Coronary Syndrome (NSTE ACS) patients were included and received loading doses of 250 mg aspirin and 600 mg clopidogrel." | 3.75 | Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response. ( Alessi, MC; Bali, L; Bonnet, JL; Camoin, L; Cuisset, T; Frere, C; Juhan-Vague, I; Lambert, M; Morange, PE; Quilici, J, 2009) |
| "Patients with ischemic stroke enrolled in the Management of Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) study underwent long-term prospective assessment of their modified Rankin Scale (mRS) score." | 3.74 | Rate, degree, and predictors of recovery from disability following ischemic stroke. ( Bego, G; Carita, P; Gabriel, S; Hakimi, Z; Hankey, GJ; Spiesser, J, 2007) |
| "Dorsal 1 cm2 skin wounds were excised on genetically diabetic 8-week to 12-week-old, Lep/r-db/db male mice, and wound healing kinetics were determined." | 1.37 | Poly-N-acetyl glucosamine fibers induce angiogenesis in ADP inhibitor-treated diabetic mice. ( Demcheva, M; Fischer, TH; Gennaoui, A; Matthews, JC; Orgill, DP; Pietramaggiori, G; Scherer, SS; Valeri, CR, 2011) |
| "Stent thrombosis is a rare but devastating complication of coronary stent implantation." | 1.35 | Stent thrombosis: a poor man's disease? ( Danenberg, HD; Lotan, C; Marincheva, G; Nassar, H; Varshitzki, B, 2009) |
Research
Studies (66)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.03) | 18.7374 |
| 1990's | 3 (4.55) | 18.2507 |
| 2000's | 32 (48.48) | 29.6817 |
| 2010's | 29 (43.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Baber, U | 1 |
| Bander, J | 1 |
| Karajgikar, R | 1 |
| Yadav, K | 1 |
| Hadi, A | 1 |
| Theodoropolous, K | 1 |
| Gukathasan, N | 1 |
| Roy, S | 1 |
| Sayeneni, S | 1 |
| Scott, SA | 1 |
| Kovacic, JC | 1 |
| Yu, J | 1 |
| Sartori, S | 1 |
| Mehran, R | 1 |
| Uribarri, J | 1 |
| Badimon, JJ | 1 |
| Muntner, P | 1 |
| Moreno, P | 1 |
| Kini, AS | 1 |
| Sharma, SK | 1 |
| Lee, SW | 2 |
| Lee, JY | 2 |
| Ahn, JM | 1 |
| Park, DW | 2 |
| Han, S | 1 |
| Park, YK | 1 |
| Lee, WS | 1 |
| Jang, JY | 1 |
| Kwon, CH | 1 |
| Park, GM | 1 |
| Cho, YR | 1 |
| Kim, WJ | 2 |
| Kang, SJ | 1 |
| Kim, YH | 2 |
| Lee, CW | 2 |
| Kim, JJ | 1 |
| Park, SW | 2 |
| Park, SJ | 2 |
| Li, G | 1 |
| Li, ZQ | 1 |
| Yang, QY | 1 |
| Yang, JD | 1 |
| Sabouret, P | 1 |
| Taiel-Sartral, M | 1 |
| Une, D | 1 |
| Al-Atassi, T | 1 |
| Kulik, A | 1 |
| Voisine, P | 1 |
| Le May, M | 1 |
| Ruel, M | 1 |
| Silber, T | 1 |
| Ziemann, U | 1 |
| Ernemann, U | 1 |
| Bischof, F | 1 |
| Kuliczkowski, W | 2 |
| Gasior, M | 2 |
| Pres, D | 2 |
| Kaczmarski, J | 2 |
| Laszowska, A | 1 |
| Szewczyk, M | 1 |
| Hawranek, M | 1 |
| Tajstra, M | 1 |
| Zeglen, S | 1 |
| Polonski, L | 2 |
| Serebruany, VL | 2 |
| Legrand, D | 1 |
| Barbato, E | 4 |
| Chenu, P | 1 |
| Magne, J | 1 |
| Vrolix, M | 1 |
| Wijns, W | 2 |
| Legrand, V | 1 |
| Bell, DS | 1 |
| Pan, Y | 1 |
| Jing, J | 1 |
| Li, H | 1 |
| Wang, Y | 2 |
| He, Y | 1 |
| Mangiacapra, F | 3 |
| Panaioli, E | 1 |
| Colaiori, I | 1 |
| Ricottini, E | 2 |
| Lauria Pantano, A | 1 |
| Pozzilli, P | 1 |
| Di Sciascio, G | 2 |
| Maeng, M | 1 |
| Jensen, LO | 1 |
| Kaltoft, A | 1 |
| Hansen, HH | 1 |
| Bøttcher, M | 1 |
| Lassen, JF | 1 |
| Thayssen, P | 1 |
| Krusell, LR | 1 |
| Rasmussen, K | 1 |
| Pedersen, L | 1 |
| Sørensen, HT | 1 |
| Johnsen, SP | 1 |
| Thuesen, L | 1 |
| Ang, L | 1 |
| Palakodeti, V | 1 |
| Khalid, A | 1 |
| Tsimikas, S | 1 |
| Idrees, Z | 1 |
| Tran, P | 1 |
| Clopton, P | 1 |
| Zafar, N | 1 |
| Bromberg-Marin, G | 1 |
| Keramati, S | 1 |
| Mahmud, E | 1 |
| Erlinge, D | 1 |
| Varenhorst, C | 1 |
| Braun, OO | 1 |
| James, S | 1 |
| Winters, KJ | 1 |
| Jakubowski, JA | 1 |
| Brandt, JT | 1 |
| Sugidachi, A | 1 |
| Siegbahn, A | 1 |
| Wallentin, L | 1 |
| Cairns, JA | 1 |
| Eikelboom, J | 1 |
| Siasos, G | 1 |
| Tousoulis, D | 1 |
| Stefanadis, C | 1 |
| Motovska, Z | 1 |
| Widimsky, P | 1 |
| Bonello-Palot, N | 1 |
| Armero, S | 1 |
| Paganelli, F | 1 |
| Mancini, J | 1 |
| De Labriolle, A | 1 |
| Bonello, C | 1 |
| Lévy, N | 1 |
| Maillard, L | 1 |
| Barragan, P | 1 |
| Dignat-George, F | 1 |
| Camoin-Jau, L | 1 |
| Bonello, L | 1 |
| Danenberg, HD | 1 |
| Marincheva, G | 1 |
| Varshitzki, B | 1 |
| Nassar, H | 1 |
| Lotan, C | 1 |
| Chun, KJ | 1 |
| Kim, HS | 1 |
| Yun, SC | 1 |
| Hong, MK | 1 |
| Rhee, KS | 1 |
| Chae, JK | 1 |
| Ko, JK | 1 |
| Park, JH | 1 |
| Lee, JH | 1 |
| Choi, SW | 1 |
| Jeong, JO | 1 |
| Seong, IW | 1 |
| Jon, S | 1 |
| Cho, YH | 1 |
| Lee, NH | 1 |
| Kim, JH | 2 |
| McClung, JA | 1 |
| Kruger, AL | 1 |
| Ferraris, A | 1 |
| Vanella, L | 1 |
| Tsenovoy, P | 1 |
| Weiss, MB | 1 |
| Abraham, NG | 1 |
| Morel, O | 2 |
| Kessler, L | 1 |
| Ohlmann, P | 2 |
| Bareiss, P | 1 |
| Patti, G | 1 |
| Peace, A | 1 |
| Gatto, L | 1 |
| Vizzi, V | 1 |
| D'Ambrosio, A | 1 |
| Muller, O | 1 |
| Peace, AJ | 1 |
| Park, KJ | 1 |
| Chung, HS | 1 |
| Kim, SR | 1 |
| Kim, HJ | 1 |
| Han, JY | 1 |
| Lee, SY | 1 |
| Greif, M | 1 |
| Carballo, S | 1 |
| Carballo, D | 1 |
| Keller, PF | 1 |
| Roffi, M | 1 |
| Scherer, SS | 1 |
| Pietramaggiori, G | 1 |
| Matthews, JC | 1 |
| Gennaoui, A | 1 |
| Demcheva, M | 1 |
| Fischer, TH | 1 |
| Valeri, CR | 1 |
| Orgill, DP | 1 |
| Hall, HM | 1 |
| Banerjee, S | 1 |
| McGuire, DK | 1 |
| Messinger-Rapport, BJ | 1 |
| Morley, JE | 1 |
| Thomas, DR | 1 |
| Gammack, JK | 1 |
| Saad, AA | 1 |
| Ismail, EA | 1 |
| Darwish, YW | 1 |
| Nasr, HA | 1 |
| Hassan, AR | 1 |
| Bedeer, I | 1 |
| Alfons, MA | 1 |
| Ferreiro, JL | 1 |
| Cequier, AR | 1 |
| Angiolillo, DJ | 2 |
| Linden, MD | 1 |
| Tran, H | 1 |
| Woods, R | 1 |
| Tonkin, A | 1 |
| Pugi, A | 1 |
| Borrone, G | 1 |
| Moschini, M | 1 |
| Lapi, F | 1 |
| Mugelli, A | 1 |
| Vannacci, A | 1 |
| El Ghannudi, S | 1 |
| Hess, S | 1 |
| Reydel, A | 1 |
| Crimizade, U | 1 |
| Jesel, L | 1 |
| Radulescu, B | 1 |
| Wiesel, ML | 1 |
| Gachet, C | 1 |
| Hess, CN | 1 |
| Broderick, S | 1 |
| Piccini, JP | 1 |
| Alexander, KP | 1 |
| Newby, LK | 1 |
| Shaw, LK | 1 |
| Mahaffey, KW | 1 |
| Alexander, JH | 1 |
| Peterson, ED | 1 |
| Granger, CB | 1 |
| Lopes, RD | 1 |
| Fihn, SD | 1 |
| Gardin, JM | 1 |
| Abrams, J | 1 |
| Berra, K | 1 |
| Blankenship, JC | 1 |
| Dallas, AP | 1 |
| Douglas, PS | 1 |
| Foody, JM | 1 |
| Gerber, TC | 1 |
| Hinderliter, AL | 1 |
| King, SB | 1 |
| Kligfield, PD | 1 |
| Krumholz, HM | 1 |
| Kwong, RY | 1 |
| Lim, MJ | 1 |
| Linderbaum, JA | 1 |
| Mack, MJ | 1 |
| Munger, MA | 1 |
| Prager, RL | 1 |
| Sabik, JF | 1 |
| Shaw, LJ | 1 |
| Sikkema, JD | 1 |
| Smith, CR | 1 |
| Smith, SC | 1 |
| Spertus, JA | 1 |
| Williams, SV | 1 |
| Ertorer, ME | 1 |
| Gokcel, A | 1 |
| Savaş, L | 1 |
| Kocak, R | 1 |
| Bhatt, DL | 1 |
| Marso, SP | 1 |
| Hirsch, AT | 1 |
| Ringleb, PA | 1 |
| Hacke, W | 1 |
| Topol, EJ | 2 |
| Locker, C | 1 |
| Mohr, R | 1 |
| Lev-Ran, O | 1 |
| Uretzky, G | 1 |
| Frimerman, A | 1 |
| Shaham, Y | 1 |
| Shapira, I | 1 |
| Mehilli, J | 2 |
| Kastrati, A | 3 |
| Schühlen, H | 1 |
| Dibra, A | 1 |
| Dotzer, F | 1 |
| von Beckerath, N | 2 |
| Bollwein, H | 1 |
| Pache, J | 1 |
| Dirschinger, J | 1 |
| Berger, PP | 1 |
| Schömig, A | 3 |
| Schnell, O | 1 |
| Standl, E | 1 |
| Popma, JJ | 1 |
| Leon, MB | 1 |
| Moses, JW | 1 |
| Holmes, DR | 1 |
| Cox, N | 1 |
| Fitzpatrick, M | 1 |
| Douglas, J | 1 |
| Lambert, C | 1 |
| Mooney, M | 1 |
| Yakubov, S | 1 |
| Kuntz, RE | 1 |
| Hankey, GJ | 2 |
| Katayama, T | 1 |
| Nakashima, H | 1 |
| Takagi, C | 1 |
| Honda, Y | 1 |
| Suzuki, S | 1 |
| Iwasaki, Y | 1 |
| Yano, K | 1 |
| Fernandez-Ortiz, A | 1 |
| Bernardo, E | 1 |
| Ramírez, C | 1 |
| Sabaté, M | 1 |
| Jimenez-Quevedo, P | 1 |
| Hernández, R | 1 |
| Moreno, R | 1 |
| Escaned, J | 1 |
| Alfonso, F | 1 |
| Bañuelos, C | 1 |
| Costa, MA | 1 |
| Bass, TA | 1 |
| Macaya, C | 1 |
| Késmárky, G | 1 |
| Fehér, G | 1 |
| Koltai, K | 1 |
| Horváth, B | 1 |
| Tóth, K | 1 |
| Sibbing, D | 1 |
| von Beckerath, O | 1 |
| Fuchs, I | 1 |
| Frossard, M | 1 |
| Spiel, A | 1 |
| Riedmüller, E | 1 |
| Laggner, AN | 1 |
| Jilma, B | 1 |
| Münzel, TF | 1 |
| Post, F | 1 |
| Lepor, NE | 1 |
| Grinius, V | 1 |
| Navickas, R | 1 |
| Unikas, R | 1 |
| Spiesser, J | 1 |
| Hakimi, Z | 1 |
| Bego, G | 1 |
| Carita, P | 1 |
| Gabriel, S | 1 |
| Iijima, R | 1 |
| Ndrepepa, G | 1 |
| Bruskina, O | 1 |
| Schulz, S | 1 |
| Ahn, Y | 1 |
| Jeong, MH | 1 |
| Jeong, JW | 1 |
| Kim, KH | 1 |
| Ahn, TH | 1 |
| Kang, WC | 1 |
| Park, CG | 1 |
| Chae, IH | 1 |
| Nam, CW | 1 |
| Hur, SH | 1 |
| Bae, JH | 1 |
| Kim, KY | 1 |
| Oh, SK | 1 |
| Beyar, R | 1 |
| Nikolsky, E | 1 |
| Cuisset, T | 1 |
| Frere, C | 1 |
| Quilici, J | 1 |
| Morange, PE | 1 |
| Camoin, L | 1 |
| Bali, L | 1 |
| Lambert, M | 1 |
| Juhan-Vague, I | 1 |
| Alessi, MC | 1 |
| Bonnet, JL | 1 |
| Grotta, J | 1 |
| Swine, C | 1 |
| Cornette, P | 1 |
| Van Pee, D | 1 |
| Delos, M | 1 |
| Melange, M | 1 |
| Lincoff, AM | 1 |
| Califf, RM | 1 |
| Moliterno, DJ | 1 |
| Ellis, SG | 1 |
| Ducas, J | 1 |
| Kramer, JH | 1 |
| Kleiman, NS | 1 |
| Cohen, EA | 1 |
| Booth, JE | 1 |
| Sapp, SK | 1 |
| Cabot, CF | 1 |
| Nair, GV | 1 |
| Davis, CJ | 1 |
| McKenzie, ME | 1 |
| Lowry, DR | 1 |
| Brouwer, MA | 1 |
| Verheugt, FW | 1 |
| Horwich, TB | 1 |
| Fonarow, GC | 1 |
| Bonnetblanc, JM | 1 |
| Julia, A | 1 |
| Rigaud, M | 1 |
| Bokarev, IN | 1 |
| Velikov, VK | 1 |
| Zelenchuk, NM | 1 |
| Iarovaia, LD | 1 |
| Polunin, GS | 1 |
Clinical Trials (8)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Preoperative FFR on Arterial Bypass Graft Functionality: Towards a New CABG Paradigm[NCT02527044] | 120 participants (Anticipated) | Interventional | 2015-11-30 | Active, not recruiting | |||
| Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial): Does Clopidogrel Prevent Saphenous Vein Graft Disease After Coronary Bypass?[NCT00228423] | Phase 2 | 113 participants (Actual) | Interventional | 2006-05-31 | Completed | ||
| Randomized,Double-blind Trial Comparing the Effects of a 3-month Clopidogrel Regimen,Combined With ASA During the First 21days,Versus ASA Alone for the Acute Treatment of TIA or Minor Stroke[NCT00979589] | Phase 3 | 5,100 participants (Actual) | Interventional | 2009-12-31 | Completed | ||
| The Role of Multiple Electrode Aggregometry in Detection of Clopidogrel Resistance in Diabetic Patients With Coronary Artery Disease and Prediction of Clinical Outcomes. A Comparative-method, Non Interventional, Single Center Study.[NCT01991093] | 280 participants (Actual) | Observational | 2014-06-30 | Completed | |||
| Routine Or Selective Stress Testing After Revascularization: ROSSTAR Trial RCT Outline[NCT03067402] | 1,100 participants (Anticipated) | Interventional | 2017-03-20 | Not yet recruiting | |||
| Register of Cardiovascular Complications Among People Living With HIV[NCT02453919] | 800 participants (Anticipated) | Observational [Patient Registry] | 2010-02-28 | Recruiting | |||
| Non-randomized, Open-label, Historical Control, Single Group Assignment Trial of a Reduced Dose of Unfractionated Heparin in Patients Undergoing Percutaneous Coronary Interventions[NCT00735280] | Phase 4 | 2,505 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| ABILITY Diabetes Global[NCT04236609] | 3,050 participants (Actual) | Interventional | 2020-06-15 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Incidence of Major Adverse Coronary Events Within One Year Following Surgery
(NCT00228423)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| 75mg Clopidogrel | 4 |
| Placebo | 5 |
Incidence of Major Bleeding Events Within One Year Following Surgery
(NCT00228423)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| 75mg Clopidogrel | 1 |
| Placebo | 0 |
Vein Graft Angiographic Patency
Postoperative angiogram 12 months post-CABG (NCT00228423)
Timeframe: One year following surgery
| Intervention | percentage (Number) |
|---|---|
| 75mg Clopidogrel | 94.3 |
| Placebo | 93.2 |
Vein Graft Intimal Area
IVUS imaging 12 months post-CABG, and the average intimal area in the proximal 40 mm of one vein graft per patient will be assessed (NCT00228423)
Timeframe: One year following surgery
| Intervention | mm (Mean) |
|---|---|
| 75mg Clopidogrel | 4.1 |
| Placebo | 4.5 |
Reviews
14 reviews available for ticlopidine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
New antiplatelet agents in the treatment of acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Clinical Trials as Topic; Clopidogrel; | 2014 |
Improving outcomes in patients undergoing percutaneous coronary intervention: role of prasugrel.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Dia | 2009 |
Diabetes and the platelet: toward new therapeutic paradigms for diabetic atherothrombosis.
Topics: Acute Coronary Syndrome; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; Diabetes Complications; D | 2010 |
Variability of clopidogrel response in patients with type 2 diabetes mellitus.
Topics: Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Monito | 2011 |
Oral antiplatelet therapy in patients with diabetes mellitus and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Cilostazol; Clopidogrel; Diabetes Complicati | 2010 |
High platelet reactivity and antiplatelet therapy resistance.
Topics: Aged; Biological Availability; Blood Platelets; Clopidogrel; Cyclooxygenase 1; Diabetes Complication | 2012 |
Comparison of bilateral thoracic artery grafting with percutaneous coronary interventions in diabetic patients.
Topics: Abciximab; Aged; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspir | 2004 |
[Cardiovascular risk in diabetes--diagnostic and therapeutic aspects].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Mon | 2004 |
Secondary prevention of recurrent stroke.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Endarterectomy; Endarterecto | 2005 |
[Pathogenesis and therapy of the acute coronary syndrome: differentiated advantage of glycoprotein IIb/IIIa receptor antagonists for high-risk patients].
Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Disease; Coronary Thrombosis; Diabetes Complic | 2006 |
Impact of chronic kidney disease and diabetes on percutaneous coronary intervention outcomes.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Cardiovascular Diseases; Clinical | 2006 |
[Stents in interventional cardiology].
Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Clop | 2007 |
Aspirin in patients with coronary artery disease: is it simply irresistible?
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Benzamidines; Clinical Trials as Topic; Clopidogrel; Cor | 2001 |
Prevention of heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Ant | 2002 |
Trials
13 trials available for ticlopidine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Comparison of dual versus triple antiplatelet therapy after drug-eluting stent according to stent length (from the pooled analysis of DECLARE trials).
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Diabetes Compl | 2013 |
The STIB score: a simple clinical test to predict clopidogrel resistance.
Topics: Aged; Angina, Stable; Angioplasty, Balloon, Coronary; Belgium; Biomarkers; Blood Platelets; Body Mas | 2015 |
Abnormal glucose regulation increases stroke risk in minor ischemic stroke or TIA.
Topics: Aged; Aspirin; Blood Glucose; Brain Ischemia; Clopidogrel; Diabetes Complications; Double-Blind Meth | 2016 |
Clopidogrel Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients Treated With Percutaneous Coronary Intervention: Results of the CLOTILDIA Study (Clopidogrel High Dose Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients).
Topics: Adenosine; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2; | 2016 |
Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.
Topics: Adult; Aged; Clopidogrel; Comorbidity; Coronary Artery Disease; Diabetes Complications; Double-Blind | 2008 |
Comparison of Triple antiplatelet therapy and dual antiplatelet therapy in patients at high risk of restenosis after drug-eluting stent implantation (from the DECLARE-DIABETES and -LONG Trials).
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Diabete | 2010 |
Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Endpoi | 2002 |
Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clopidogrel; Coronary Arter | 2004 |
Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries.
Topics: Aged; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Coronary Restenosis; Coronary S | 2004 |
Diabetes mellitus and platelet function after administration of aspirin and a single 600 mg dose of clopidogrel.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; | 2006 |
Relationship between platelet count and 30-day clinical outcomes after percutaneous coronary interventions. Pooled analysis of four ISAR trials.
Topics: Abciximab; Acute Coronary Syndrome; Aged; Angiography; Angioplasty, Balloon, Coronary; Antibodies, M | 2007 |
Randomized comparison of cilostazol vs clopidogrel after drug-eluting stenting in diabetic patients--clilostazol for diabetic patients in drug-eluting stent (CIDES) trial.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Rest | 2008 |
Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Combined Modality Therapy; Corona | 1999 |
Other Studies
39 other studies available for ticlopidine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Combined and independent impact of diabetes mellitus and chronic kidney disease on residual platelet reactivity.
Topics: Aged; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Female; Humans; Kidney Diseases; Male; | 2013 |
Acquired pure red cell aplasia due to treatment with clopidogrel: first case report.
Topics: Clopidogrel; Coronary Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hy | 2014 |
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C | 2014 |
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C | 2014 |
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C | 2014 |
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C | 2014 |
Analysis of periinterventional complications of intracranial angioplasty and stenting: a single center experience.
Topics: Aged; Angioplasty; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Diabetes Complication | 2014 |
Aspirin 'resistance': impact on no-reflow, platelet and inflammatory biomarkers in diabetics after ST-segment elevation myocardial infarction.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Diabetes Complications; Drug Resistance; Female; Humans; Inf | 2015 |
Aspirin in the prevention of cardiovascular events in patients with diabetes.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Drug Admin | 2016 |
Comparison of stent thrombosis, myocardial infarction, and mortality following drug-eluting versus bare-metal stent coronary intervention in patients with diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Denmark; Diabetes Complications; Drug-Eluting Stents; Female; Humans; Ma | 2008 |
Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel.
Topics: Aged; Body Mass Index; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Female; Fibrino | 2008 |
The pursuit of clinically relevant measures of platelet function after antiplatelet drug therapy.
Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Humans; Piperazines; | 2008 |
Multiple mechanisms affect the clopidogrel response.
Topics: Biomarkers; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Diabetes Complicat | 2009 |
Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Body Mass Index; Clopidogrel; C | 2009 |
Stent thrombosis: a poor man's disease?
Topics: Acute Disease; Aged; Angioplasty, Balloon, Coronary; Chi-Square Distribution; Clopidogrel; Cohort St | 2009 |
Usefulness of clopidogrel to protect against diabetes-induced vascular damage.
Topics: Adult; Aged; Cell Count; Clopidogrel; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelial | 2010 |
Comparison of platelet reactivity and periprocedural outcomes in patients with versus without diabetes mellitus and treated with clopidogrel and percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Case-Control Studies; Clopidogrel; Cohort Studies; Coronary St | 2010 |
Lack of correlation between platelet reactivity and glycaemic control in type 2 diabetes mellitus patients treated with aspirin and clopidogrel.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Blood Glucose; Blood Platelets; Clopidogrel; Diab | 2011 |
Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Asian People | 2011 |
Effects of platelet and inflammatory system activation on outcomes in diabetic patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Diabetes Complicati | 2011 |
[Specificities of diabetes in acute coronary syndromes].
Topics: Acute Coronary Syndrome; Algorithms; Angioplasty; Anti-Inflammatory Agents, Non-Steroidal; Clopidogr | 2011 |
Poly-N-acetyl glucosamine fibers induce angiogenesis in ADP inhibitor-treated diabetic mice.
Topics: Acetylglucosamine; Animals; Clopidogrel; Diabetes Complications; Male; Mice; Mice, Inbred C57BL; Nan | 2011 |
Clinical update on nursing home medicine: 2011.
Topics: Anti-Ulcer Agents; Anticoagulants; Atrial Fibrillation; Clopidogrel; Clostridioides difficile; Delir | 2011 |
Platelet function profile post-clopidogrel therapy in patients with type 2 diabetes undergoing coronary stent implantation.
Topics: Aged; Clopidogrel; Coronary Vessels; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Huma | 2012 |
An unusual case of systolic hypertension associated with ticlopidine treatment.
Topics: Aged, 80 and over; Blood Pressure; Cardiology; Carotid Arteries; Diabetes Complications; Female; Gas | 2012 |
The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus patients with acute coronary syndrome is not related to glycaemic control: roles of white blood cell count and body weight.
Topics: Acute Coronary Syndrome; Aged; Body Weight; Clopidogrel; Diabetes Complications; Diabetes Mellitus; | 2012 |
Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients.
Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cor | 2012 |
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight | 2012 |
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight | 2012 |
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight | 2012 |
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight | 2012 |
Ticlopidine-induced marrow aplasia treated with cyclosporine.
Topics: Bone Marrow Diseases; Cyclosporine; Diabetes Complications; Diabetes Mellitus; Humans; Male; Middle | 2002 |
[Even when walking yet does not cause any pain, peripheral arterial occlusive disease costs life years].
Topics: Arterial Occlusive Diseases; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Humans; | 2003 |
Clinical outcomes and left ventricular function in diabetic patients with acute myocardial infarction treated by primary coronary angioplasty.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Dia | 2005 |
Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Fema | 2006 |
Viscosity, hemostasis and inflammation in atherosclerotic heart diseases.
Topics: Aged; Aspirin; Blood Viscosity; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Diabetes Compl | 2006 |
Platelet function in patients with acute coronary syndrome (ACS) predicts recurrent ACS.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aspirin; Clopidogrel; Coronary Disease; Diabetes Complic | 2006 |
Rate, degree, and predictors of recovery from disability following ischemic stroke.
Topics: Aged; Brain Ischemia; Causality; Clopidogrel; Cohort Studies; Diabetes Complications; Disability Eva | 2007 |
Drug-eluting versus bare-metal stents: when and for whom?
Topics: Angioplasty, Balloon, Coronary; Canada; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; D | 2008 |
Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Arachidonic Acid; Aspirin; Body Mass Index; Cell Adhesio | 2009 |
Is aspirin effective in preventing strokes in diabetic patients?
Topics: Aspirin; Cerebrovascular Disorders; Diabetes Complications; Humans; Ticlopidine | 1993 |
[Ticlopidine, diarrhea and lymphocytic colitis].
Topics: Aged; Aged, 80 and over; Colitis; Diabetes Complications; Diabetes Mellitus; Diarrhea; Female; Human | 1998 |
Oral anticoagulation for acute coronary syndromes.
Topics: Administration, Oral; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Clopi | 2002 |
Antithrombotic agents in necrobiosis lipoidica.
Topics: Adolescent; Adult; Diabetes Complications; Female; Fibrinolytic Agents; Humans; Necrobiosis Lipoidic | 1986 |
[Effect of ticlopidine on hemostasis in patients with diabetic microangiopathy].
Topics: Adolescent; Adult; Diabetes Complications; Diabetic Retinopathy; Female; Hemostasis; Humans; Male; M | 1988 |