Page last updated: 2024-11-05

ticlopidine and Complications of Diabetes Mellitus

ticlopidine has been researched along with Complications of Diabetes Mellitus in 66 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"The effects of dual antiplatelet therapy with aspirin and clopidogrel on the progression of native coronary artery disease after coronary artery bypass grafting are unknown."7.80Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial. ( Al-Atassi, T; Kulik, A; Le May, M; Ruel, M; Une, D; Voisine, P, 2014)
"Clopidogrel has been widely used to prevent recurrent ischemia in patients with acute coronary syndrome (ACS)."7.77Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome. ( Chung, HS; Han, JY; Kim, HJ; Kim, SR; Lee, SY; Park, KJ, 2011)
"635 Non ST Elevation Acute Coronary Syndrome (NSTE ACS) patients were included and received loading doses of 250 mg aspirin and 600 mg clopidogrel."7.75Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response. ( Alessi, MC; Bali, L; Bonnet, JL; Camoin, L; Cuisset, T; Frere, C; Juhan-Vague, I; Lambert, M; Morange, PE; Quilici, J, 2009)
"We evaluated the prevalence and mechanism of poor responsiveness to clopidogrel and prasugrel in coronary artery disease patients with and without diabetes."5.13Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. ( Brandt, JT; Braun, OO; Erlinge, D; Jakubowski, JA; James, S; Siegbahn, A; Sugidachi, A; Varenhorst, C; Wallentin, L; Winters, KJ, 2008)
"This study (Intracoronary Stenting and Antithrombotic Regimen: Is Abciximab a Superior Way to Eliminate Elevated Thrombotic Risk in Diabetics [ISAR-SWEET] Study) enrolled 701 diabetic patients with coronary artery disease who underwent an elective percutaneous coronary intervention after pretreatment with a 600-mg dose of clopidogrel >2 hours before the procedure: 351 patients were randomly assigned to abciximab and 350 patients to placebo."5.11Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel. ( Berger, PP; Bollwein, H; Dibra, A; Dirschinger, J; Dotzer, F; Kastrati, A; Mehilli, J; Pache, J; Schömig, A; Schühlen, H; von Beckerath, N, 2004)
" Platelet dysfunction has been implicated as a central contributor to the increased risk of coronary artery disease in patients with DM, and it is not surprising that the anti-platelet agent, clopidogrel, has been shown to have efficacy in both short and long term outcomes in patients with acute coronary syndrome and those undergoing percutaneous coronary intervention."4.87Variability of clopidogrel response in patients with type 2 diabetes mellitus. ( Banerjee, S; Hall, HM; McGuire, DK, 2011)
"A 62-year-old woman with hypertension, type 2 diabetes mellitus, hyperlipemia and coronary heart disease started taking clopidogrel, with no addition of any other new drugs."3.80Acquired pure red cell aplasia due to treatment with clopidogrel: first case report. ( Li, G; Li, ZQ; Yang, JD; Yang, QY, 2014)
"The effects of dual antiplatelet therapy with aspirin and clopidogrel on the progression of native coronary artery disease after coronary artery bypass grafting are unknown."3.80Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial. ( Al-Atassi, T; Kulik, A; Le May, M; Ruel, M; Une, D; Voisine, P, 2014)
"Clopidogrel has been widely used to prevent recurrent ischemia in patients with acute coronary syndrome (ACS)."3.77Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome. ( Chung, HS; Han, JY; Kim, HJ; Kim, SR; Lee, SY; Park, KJ, 2011)
"635 Non ST Elevation Acute Coronary Syndrome (NSTE ACS) patients were included and received loading doses of 250 mg aspirin and 600 mg clopidogrel."3.75Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response. ( Alessi, MC; Bali, L; Bonnet, JL; Camoin, L; Cuisset, T; Frere, C; Juhan-Vague, I; Lambert, M; Morange, PE; Quilici, J, 2009)
"Patients with ischemic stroke enrolled in the Management of Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) study underwent long-term prospective assessment of their modified Rankin Scale (mRS) score."3.74Rate, degree, and predictors of recovery from disability following ischemic stroke. ( Bego, G; Carita, P; Gabriel, S; Hakimi, Z; Hankey, GJ; Spiesser, J, 2007)
"Dorsal 1 cm2 skin wounds were excised on genetically diabetic 8-week to 12-week-old, Lep/r-db/db male mice, and wound healing kinetics were determined."1.37Poly-N-acetyl glucosamine fibers induce angiogenesis in ADP inhibitor-treated diabetic mice. ( Demcheva, M; Fischer, TH; Gennaoui, A; Matthews, JC; Orgill, DP; Pietramaggiori, G; Scherer, SS; Valeri, CR, 2011)
"Stent thrombosis is a rare but devastating complication of coronary stent implantation."1.35Stent thrombosis: a poor man's disease? ( Danenberg, HD; Lotan, C; Marincheva, G; Nassar, H; Varshitzki, B, 2009)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.03)18.7374
1990's3 (4.55)18.2507
2000's32 (48.48)29.6817
2010's29 (43.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baber, U1
Bander, J1
Karajgikar, R1
Yadav, K1
Hadi, A1
Theodoropolous, K1
Gukathasan, N1
Roy, S1
Sayeneni, S1
Scott, SA1
Kovacic, JC1
Yu, J1
Sartori, S1
Mehran, R1
Uribarri, J1
Badimon, JJ1
Muntner, P1
Moreno, P1
Kini, AS1
Sharma, SK1
Lee, SW2
Lee, JY2
Ahn, JM1
Park, DW2
Han, S1
Park, YK1
Lee, WS1
Jang, JY1
Kwon, CH1
Park, GM1
Cho, YR1
Kim, WJ2
Kang, SJ1
Kim, YH2
Lee, CW2
Kim, JJ1
Park, SW2
Park, SJ2
Li, G1
Li, ZQ1
Yang, QY1
Yang, JD1
Sabouret, P1
Taiel-Sartral, M1
Une, D1
Al-Atassi, T1
Kulik, A1
Voisine, P1
Le May, M1
Ruel, M1
Silber, T1
Ziemann, U1
Ernemann, U1
Bischof, F1
Kuliczkowski, W2
Gasior, M2
Pres, D2
Kaczmarski, J2
Laszowska, A1
Szewczyk, M1
Hawranek, M1
Tajstra, M1
Zeglen, S1
Polonski, L2
Serebruany, VL2
Legrand, D1
Barbato, E4
Chenu, P1
Magne, J1
Vrolix, M1
Wijns, W2
Legrand, V1
Bell, DS1
Pan, Y1
Jing, J1
Li, H1
Wang, Y2
He, Y1
Mangiacapra, F3
Panaioli, E1
Colaiori, I1
Ricottini, E2
Lauria Pantano, A1
Pozzilli, P1
Di Sciascio, G2
Maeng, M1
Jensen, LO1
Kaltoft, A1
Hansen, HH1
Bøttcher, M1
Lassen, JF1
Thayssen, P1
Krusell, LR1
Rasmussen, K1
Pedersen, L1
Sørensen, HT1
Johnsen, SP1
Thuesen, L1
Ang, L1
Palakodeti, V1
Khalid, A1
Tsimikas, S1
Idrees, Z1
Tran, P1
Clopton, P1
Zafar, N1
Bromberg-Marin, G1
Keramati, S1
Mahmud, E1
Erlinge, D1
Varenhorst, C1
Braun, OO1
James, S1
Winters, KJ1
Jakubowski, JA1
Brandt, JT1
Sugidachi, A1
Siegbahn, A1
Wallentin, L1
Cairns, JA1
Eikelboom, J1
Siasos, G1
Tousoulis, D1
Stefanadis, C1
Motovska, Z1
Widimsky, P1
Bonello-Palot, N1
Armero, S1
Paganelli, F1
Mancini, J1
De Labriolle, A1
Bonello, C1
Lévy, N1
Maillard, L1
Barragan, P1
Dignat-George, F1
Camoin-Jau, L1
Bonello, L1
Danenberg, HD1
Marincheva, G1
Varshitzki, B1
Nassar, H1
Lotan, C1
Chun, KJ1
Kim, HS1
Yun, SC1
Hong, MK1
Rhee, KS1
Chae, JK1
Ko, JK1
Park, JH1
Lee, JH1
Choi, SW1
Jeong, JO1
Seong, IW1
Jon, S1
Cho, YH1
Lee, NH1
Kim, JH2
McClung, JA1
Kruger, AL1
Ferraris, A1
Vanella, L1
Tsenovoy, P1
Weiss, MB1
Abraham, NG1
Morel, O2
Kessler, L1
Ohlmann, P2
Bareiss, P1
Patti, G1
Peace, A1
Gatto, L1
Vizzi, V1
D'Ambrosio, A1
Muller, O1
Peace, AJ1
Park, KJ1
Chung, HS1
Kim, SR1
Kim, HJ1
Han, JY1
Lee, SY1
Greif, M1
Carballo, S1
Carballo, D1
Keller, PF1
Roffi, M1
Scherer, SS1
Pietramaggiori, G1
Matthews, JC1
Gennaoui, A1
Demcheva, M1
Fischer, TH1
Valeri, CR1
Orgill, DP1
Hall, HM1
Banerjee, S1
McGuire, DK1
Messinger-Rapport, BJ1
Morley, JE1
Thomas, DR1
Gammack, JK1
Saad, AA1
Ismail, EA1
Darwish, YW1
Nasr, HA1
Hassan, AR1
Bedeer, I1
Alfons, MA1
Ferreiro, JL1
Cequier, AR1
Angiolillo, DJ2
Linden, MD1
Tran, H1
Woods, R1
Tonkin, A1
Pugi, A1
Borrone, G1
Moschini, M1
Lapi, F1
Mugelli, A1
Vannacci, A1
El Ghannudi, S1
Hess, S1
Reydel, A1
Crimizade, U1
Jesel, L1
Radulescu, B1
Wiesel, ML1
Gachet, C1
Hess, CN1
Broderick, S1
Piccini, JP1
Alexander, KP1
Newby, LK1
Shaw, LK1
Mahaffey, KW1
Alexander, JH1
Peterson, ED1
Granger, CB1
Lopes, RD1
Fihn, SD1
Gardin, JM1
Abrams, J1
Berra, K1
Blankenship, JC1
Dallas, AP1
Douglas, PS1
Foody, JM1
Gerber, TC1
Hinderliter, AL1
King, SB1
Kligfield, PD1
Krumholz, HM1
Kwong, RY1
Lim, MJ1
Linderbaum, JA1
Mack, MJ1
Munger, MA1
Prager, RL1
Sabik, JF1
Shaw, LJ1
Sikkema, JD1
Smith, CR1
Smith, SC1
Spertus, JA1
Williams, SV1
Ertorer, ME1
Gokcel, A1
Savaş, L1
Kocak, R1
Bhatt, DL1
Marso, SP1
Hirsch, AT1
Ringleb, PA1
Hacke, W1
Topol, EJ2
Locker, C1
Mohr, R1
Lev-Ran, O1
Uretzky, G1
Frimerman, A1
Shaham, Y1
Shapira, I1
Mehilli, J2
Kastrati, A3
Schühlen, H1
Dibra, A1
Dotzer, F1
von Beckerath, N2
Bollwein, H1
Pache, J1
Dirschinger, J1
Berger, PP1
Schömig, A3
Schnell, O1
Standl, E1
Popma, JJ1
Leon, MB1
Moses, JW1
Holmes, DR1
Cox, N1
Fitzpatrick, M1
Douglas, J1
Lambert, C1
Mooney, M1
Yakubov, S1
Kuntz, RE1
Hankey, GJ2
Katayama, T1
Nakashima, H1
Takagi, C1
Honda, Y1
Suzuki, S1
Iwasaki, Y1
Yano, K1
Fernandez-Ortiz, A1
Bernardo, E1
Ramírez, C1
Sabaté, M1
Jimenez-Quevedo, P1
Hernández, R1
Moreno, R1
Escaned, J1
Alfonso, F1
Bañuelos, C1
Costa, MA1
Bass, TA1
Macaya, C1
Késmárky, G1
Fehér, G1
Koltai, K1
Horváth, B1
Tóth, K1
Sibbing, D1
von Beckerath, O1
Fuchs, I1
Frossard, M1
Spiel, A1
Riedmüller, E1
Laggner, AN1
Jilma, B1
Münzel, TF1
Post, F1
Lepor, NE1
Grinius, V1
Navickas, R1
Unikas, R1
Spiesser, J1
Hakimi, Z1
Bego, G1
Carita, P1
Gabriel, S1
Iijima, R1
Ndrepepa, G1
Bruskina, O1
Schulz, S1
Ahn, Y1
Jeong, MH1
Jeong, JW1
Kim, KH1
Ahn, TH1
Kang, WC1
Park, CG1
Chae, IH1
Nam, CW1
Hur, SH1
Bae, JH1
Kim, KY1
Oh, SK1
Beyar, R1
Nikolsky, E1
Cuisset, T1
Frere, C1
Quilici, J1
Morange, PE1
Camoin, L1
Bali, L1
Lambert, M1
Juhan-Vague, I1
Alessi, MC1
Bonnet, JL1
Grotta, J1
Swine, C1
Cornette, P1
Van Pee, D1
Delos, M1
Melange, M1
Lincoff, AM1
Califf, RM1
Moliterno, DJ1
Ellis, SG1
Ducas, J1
Kramer, JH1
Kleiman, NS1
Cohen, EA1
Booth, JE1
Sapp, SK1
Cabot, CF1
Nair, GV1
Davis, CJ1
McKenzie, ME1
Lowry, DR1
Brouwer, MA1
Verheugt, FW1
Horwich, TB1
Fonarow, GC1
Bonnetblanc, JM1
Julia, A1
Rigaud, M1
Bokarev, IN1
Velikov, VK1
Zelenchuk, NM1
Iarovaia, LD1
Polunin, GS1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Preoperative FFR on Arterial Bypass Graft Functionality: Towards a New CABG Paradigm[NCT02527044]120 participants (Anticipated)Interventional2015-11-30Active, not recruiting
Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial): Does Clopidogrel Prevent Saphenous Vein Graft Disease After Coronary Bypass?[NCT00228423]Phase 2113 participants (Actual)Interventional2006-05-31Completed
Randomized,Double-blind Trial Comparing the Effects of a 3-month Clopidogrel Regimen,Combined With ASA During the First 21days,Versus ASA Alone for the Acute Treatment of TIA or Minor Stroke[NCT00979589]Phase 35,100 participants (Actual)Interventional2009-12-31Completed
The Role of Multiple Electrode Aggregometry in Detection of Clopidogrel Resistance in Diabetic Patients With Coronary Artery Disease and Prediction of Clinical Outcomes. A Comparative-method, Non Interventional, Single Center Study.[NCT01991093]280 participants (Actual)Observational2014-06-30Completed
Routine Or Selective Stress Testing After Revascularization: ROSSTAR Trial RCT Outline[NCT03067402]1,100 participants (Anticipated)Interventional2017-03-20Not yet recruiting
Register of Cardiovascular Complications Among People Living With HIV[NCT02453919]800 participants (Anticipated)Observational [Patient Registry]2010-02-28Recruiting
Non-randomized, Open-label, Historical Control, Single Group Assignment Trial of a Reduced Dose of Unfractionated Heparin in Patients Undergoing Percutaneous Coronary Interventions[NCT00735280]Phase 42,505 participants (Actual)Interventional2008-08-31Completed
ABILITY Diabetes Global[NCT04236609]3,050 participants (Actual)Interventional2020-06-15Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Major Adverse Coronary Events Within One Year Following Surgery

(NCT00228423)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
75mg Clopidogrel4
Placebo5

Incidence of Major Bleeding Events Within One Year Following Surgery

(NCT00228423)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
75mg Clopidogrel1
Placebo0

Vein Graft Angiographic Patency

Postoperative angiogram 12 months post-CABG (NCT00228423)
Timeframe: One year following surgery

Interventionpercentage (Number)
75mg Clopidogrel94.3
Placebo93.2

Vein Graft Intimal Area

IVUS imaging 12 months post-CABG, and the average intimal area in the proximal 40 mm of one vein graft per patient will be assessed (NCT00228423)
Timeframe: One year following surgery

Interventionmm (Mean)
75mg Clopidogrel4.1
Placebo4.5

Reviews

14 reviews available for ticlopidine and Complications of Diabetes Mellitus

ArticleYear
New antiplatelet agents in the treatment of acute coronary syndromes.
    Archives of cardiovascular diseases, 2014, Volume: 107, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Clinical Trials as Topic; Clopidogrel;

2014
Improving outcomes in patients undergoing percutaneous coronary intervention: role of prasugrel.
    Vascular health and risk management, 2009, Volume: 5, Issue:1

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Dia

2009
Diabetes and the platelet: toward new therapeutic paradigms for diabetic atherothrombosis.
    Atherosclerosis, 2010, Volume: 212, Issue:2

    Topics: Acute Coronary Syndrome; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; Diabetes Complications; D

2010
Variability of clopidogrel response in patients with type 2 diabetes mellitus.
    Diabetes & vascular disease research, 2011, Volume: 8, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Monito

2011
Oral antiplatelet therapy in patients with diabetes mellitus and acute coronary syndromes.
    Trends in cardiovascular medicine, 2010, Volume: 20, Issue:7

    Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Cilostazol; Clopidogrel; Diabetes Complicati

2010
High platelet reactivity and antiplatelet therapy resistance.
    Seminars in thrombosis and hemostasis, 2012, Volume: 38, Issue:2

    Topics: Aged; Biological Availability; Blood Platelets; Clopidogrel; Cyclooxygenase 1; Diabetes Complication

2012
Comparison of bilateral thoracic artery grafting with percutaneous coronary interventions in diabetic patients.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:2

    Topics: Abciximab; Aged; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspir

2004
[Cardiovascular risk in diabetes--diagnostic and therapeutic aspects].
    MMW Fortschritte der Medizin, 2004, Sep-02, Volume: 146, Issue:35-36

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Mon

2004
Secondary prevention of recurrent stroke.
    Stroke, 2005, Volume: 36, Issue:2

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Endarterectomy; Endarterecto

2005
[Pathogenesis and therapy of the acute coronary syndrome: differentiated advantage of glycoprotein IIb/IIIa receptor antagonists for high-risk patients].
    Deutsche medizinische Wochenschrift (1946), 2006, Nov-24, Volume: 131, Issue:47 Suppl 7

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Disease; Coronary Thrombosis; Diabetes Complic

2006
Impact of chronic kidney disease and diabetes on percutaneous coronary intervention outcomes.
    Reviews in cardiovascular medicine, 2006, Volume: 7 Suppl 4

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Cardiovascular Diseases; Clinical

2006
[Stents in interventional cardiology].
    Medicina (Kaunas, Lithuania), 2007, Volume: 43, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Clop

2007
Aspirin in patients with coronary artery disease: is it simply irresistible?
    Journal of thrombosis and thrombolysis, 2001, Volume: 11, Issue:2

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Benzamidines; Clinical Trials as Topic; Clopidogrel; Cor

2001
Prevention of heart failure.
    Current cardiology reports, 2002, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Ant

2002

Trials

13 trials available for ticlopidine and Complications of Diabetes Mellitus

ArticleYear
Comparison of dual versus triple antiplatelet therapy after drug-eluting stent according to stent length (from the pooled analysis of DECLARE trials).
    The American journal of cardiology, 2013, Dec-01, Volume: 112, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Diabetes Compl

2013
The STIB score: a simple clinical test to predict clopidogrel resistance.
    Acta cardiologica, 2015, Volume: 70, Issue:5

    Topics: Aged; Angina, Stable; Angioplasty, Balloon, Coronary; Belgium; Biomarkers; Blood Platelets; Body Mas

2015
Abnormal glucose regulation increases stroke risk in minor ischemic stroke or TIA.
    Neurology, 2016, Oct-11, Volume: 87, Issue:15

    Topics: Aged; Aspirin; Blood Glucose; Brain Ischemia; Clopidogrel; Diabetes Complications; Double-Blind Meth

2016
Clopidogrel Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients Treated With Percutaneous Coronary Intervention: Results of the CLOTILDIA Study (Clopidogrel High Dose Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients).
    Circulation, 2016, Sep-13, Volume: 134, Issue:11

    Topics: Adenosine; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2;

2016
Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Adult; Aged; Clopidogrel; Comorbidity; Coronary Artery Disease; Diabetes Complications; Double-Blind

2008
Comparison of Triple antiplatelet therapy and dual antiplatelet therapy in patients at high risk of restenosis after drug-eluting stent implantation (from the DECLARE-DIABETES and -LONG Trials).
    The American journal of cardiology, 2010, Jan-15, Volume: 105, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Diabete

2010
Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus.
    The American journal of cardiology, 2002, Sep-15, Volume: 90, Issue:6

    Topics: Aged; Aspirin; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Endpoi

2002
Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel.
    Circulation, 2004, Dec-14, Volume: 110, Issue:24

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clopidogrel; Coronary Arter

2004
Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries.
    Circulation, 2004, Dec-21, Volume: 110, Issue:25

    Topics: Aged; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Coronary Restenosis; Coronary S

2004
Diabetes mellitus and platelet function after administration of aspirin and a single 600 mg dose of clopidogrel.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel;

2006
Relationship between platelet count and 30-day clinical outcomes after percutaneous coronary interventions. Pooled analysis of four ISAR trials.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:4

    Topics: Abciximab; Acute Coronary Syndrome; Aged; Angiography; Angioplasty, Balloon, Coronary; Antibodies, M

2007
Randomized comparison of cilostazol vs clopidogrel after drug-eluting stenting in diabetic patients--clilostazol for diabetic patients in drug-eluting stent (CIDES) trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:1

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Rest

2008
Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators.
    The New England journal of medicine, 1999, Jul-29, Volume: 341, Issue:5

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Combined Modality Therapy; Corona

1999

Other Studies

39 other studies available for ticlopidine and Complications of Diabetes Mellitus

ArticleYear
Combined and independent impact of diabetes mellitus and chronic kidney disease on residual platelet reactivity.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:1

    Topics: Aged; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Female; Humans; Kidney Diseases; Male;

2013
Acquired pure red cell aplasia due to treatment with clopidogrel: first case report.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:2

    Topics: Clopidogrel; Coronary Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hy

2014
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
    Circulation, 2014, Sep-09, Volume: 130, Issue:11 Suppl 1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C

2014
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
    Circulation, 2014, Sep-09, Volume: 130, Issue:11 Suppl 1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C

2014
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
    Circulation, 2014, Sep-09, Volume: 130, Issue:11 Suppl 1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C

2014
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
    Circulation, 2014, Sep-09, Volume: 130, Issue:11 Suppl 1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; C

2014
Analysis of periinterventional complications of intracranial angioplasty and stenting: a single center experience.
    European journal of radiology, 2014, Volume: 83, Issue:12

    Topics: Aged; Angioplasty; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Diabetes Complication

2014
Aspirin 'resistance': impact on no-reflow, platelet and inflammatory biomarkers in diabetics after ST-segment elevation myocardial infarction.
    Cardiology, 2015, Volume: 131, Issue:1

    Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Diabetes Complications; Drug Resistance; Female; Humans; Inf

2015
Aspirin in the prevention of cardiovascular events in patients with diabetes.
    Postgraduate medicine, 2016, Volume: 128, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Drug Admin

2016
Comparison of stent thrombosis, myocardial infarction, and mortality following drug-eluting versus bare-metal stent coronary intervention in patients with diabetes mellitus.
    The American journal of cardiology, 2008, Jul-15, Volume: 102, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Denmark; Diabetes Complications; Drug-Eluting Stents; Female; Humans; Ma

2008
Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel.
    Journal of the American College of Cardiology, 2008, Sep-23, Volume: 52, Issue:13

    Topics: Aged; Body Mass Index; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Female; Fibrino

2008
The pursuit of clinically relevant measures of platelet function after antiplatelet drug therapy.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Humans; Piperazines;

2008
Multiple mechanisms affect the clopidogrel response.
    Journal of the American College of Cardiology, 2009, Mar-10, Volume: 53, Issue:10

    Topics: Biomarkers; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Diabetes Complicat

2009
Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2009, Dec-01, Volume: 104, Issue:11

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Body Mass Index; Clopidogrel; C

2009
Stent thrombosis: a poor man's disease?
    The Israel Medical Association journal : IMAJ, 2009, Volume: 11, Issue:9

    Topics: Acute Disease; Aged; Angioplasty, Balloon, Coronary; Chi-Square Distribution; Clopidogrel; Cohort St

2009
Usefulness of clopidogrel to protect against diabetes-induced vascular damage.
    The American journal of cardiology, 2010, Apr-01, Volume: 105, Issue:7

    Topics: Adult; Aged; Cell Count; Clopidogrel; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelial

2010
Comparison of platelet reactivity and periprocedural outcomes in patients with versus without diabetes mellitus and treated with clopidogrel and percutaneous coronary intervention.
    The American journal of cardiology, 2010, Sep-01, Volume: 106, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Case-Control Studies; Clopidogrel; Cohort Studies; Coronary St

2010
Lack of correlation between platelet reactivity and glycaemic control in type 2 diabetes mellitus patients treated with aspirin and clopidogrel.
    Journal of thrombosis and thrombolysis, 2011, Volume: 32, Issue:1

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Blood Glucose; Blood Platelets; Clopidogrel; Diab

2011
Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome.
    The Korean journal of laboratory medicine, 2011, Volume: 31, Issue:2

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Asian People

2011
Effects of platelet and inflammatory system activation on outcomes in diabetic patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
    Kardiologia polska, 2011, Volume: 69, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Diabetes Complicati

2011
[Specificities of diabetes in acute coronary syndromes].
    Revue medicale suisse, 2011, Jun-01, Volume: 7, Issue:297

    Topics: Acute Coronary Syndrome; Algorithms; Angioplasty; Anti-Inflammatory Agents, Non-Steroidal; Clopidogr

2011
Poly-N-acetyl glucosamine fibers induce angiogenesis in ADP inhibitor-treated diabetic mice.
    The Journal of trauma, 2011, Volume: 71, Issue:2 Suppl 1

    Topics: Acetylglucosamine; Animals; Clopidogrel; Diabetes Complications; Male; Mice; Mice, Inbred C57BL; Nan

2011
Clinical update on nursing home medicine: 2011.
    Journal of the American Medical Directors Association, 2011, Volume: 12, Issue:9

    Topics: Anti-Ulcer Agents; Anticoagulants; Atrial Fibrillation; Clopidogrel; Clostridioides difficile; Delir

2011
Platelet function profile post-clopidogrel therapy in patients with type 2 diabetes undergoing coronary stent implantation.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2012, Volume: 18, Issue:3

    Topics: Aged; Clopidogrel; Coronary Vessels; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Huma

2012
An unusual case of systolic hypertension associated with ticlopidine treatment.
    Journal of hypertension, 2012, Volume: 30, Issue:5

    Topics: Aged, 80 and over; Blood Pressure; Cardiology; Carotid Arteries; Diabetes Complications; Female; Gas

2012
The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus patients with acute coronary syndrome is not related to glycaemic control: roles of white blood cell count and body weight.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Body Weight; Clopidogrel; Diabetes Complications; Diabetes Mellitus;

2012
Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients.
    American heart journal, 2012, Volume: 164, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cor

2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
    Journal of the American College of Cardiology, 2012, Dec-18, Volume: 60, Issue:24

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight

2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
    Journal of the American College of Cardiology, 2012, Dec-18, Volume: 60, Issue:24

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight

2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
    Journal of the American College of Cardiology, 2012, Dec-18, Volume: 60, Issue:24

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight

2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
    Journal of the American College of Cardiology, 2012, Dec-18, Volume: 60, Issue:24

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight

2012
Ticlopidine-induced marrow aplasia treated with cyclosporine.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2002, Volume: 8, Issue:2

    Topics: Bone Marrow Diseases; Cyclosporine; Diabetes Complications; Diabetes Mellitus; Humans; Male; Middle

2002
[Even when walking yet does not cause any pain, peripheral arterial occlusive disease costs life years].
    MMW Fortschritte der Medizin, 2003, Apr-10, Volume: 145, Issue:15

    Topics: Arterial Occlusive Diseases; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Humans;

2003
Clinical outcomes and left ventricular function in diabetic patients with acute myocardial infarction treated by primary coronary angioplasty.
    International heart journal, 2005, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Dia

2005
Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease.
    Diabetes, 2006, Volume: 55, Issue:3

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Fema

2006
Viscosity, hemostasis and inflammation in atherosclerotic heart diseases.
    Clinical hemorheology and microcirculation, 2006, Volume: 35, Issue:1-2

    Topics: Aged; Aspirin; Blood Viscosity; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Diabetes Compl

2006
Platelet function in patients with acute coronary syndrome (ACS) predicts recurrent ACS.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aspirin; Clopidogrel; Coronary Disease; Diabetes Complic

2006
Rate, degree, and predictors of recovery from disability following ischemic stroke.
    Neurology, 2007, May-08, Volume: 68, Issue:19

    Topics: Aged; Brain Ischemia; Causality; Clopidogrel; Cohort Studies; Diabetes Complications; Disability Eva

2007
Drug-eluting versus bare-metal stents: when and for whom?
    The Journal of invasive cardiology, 2008, Volume: 20, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Canada; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; D

2008
Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response.
    Thrombosis research, 2009, Volume: 123, Issue:4

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Arachidonic Acid; Aspirin; Body Mass Index; Cell Adhesio

2009
Is aspirin effective in preventing strokes in diabetic patients?
    Stroke, 1993, Volume: 24, Issue:5

    Topics: Aspirin; Cerebrovascular Disorders; Diabetes Complications; Humans; Ticlopidine

1993
[Ticlopidine, diarrhea and lymphocytic colitis].
    Gastroenterologie clinique et biologique, 1998, Volume: 22, Issue:4

    Topics: Aged; Aged, 80 and over; Colitis; Diabetes Complications; Diabetes Mellitus; Diarrhea; Female; Human

1998
Oral anticoagulation for acute coronary syndromes.
    Circulation, 2002, Mar-19, Volume: 105, Issue:11

    Topics: Administration, Oral; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Clopi

2002
Antithrombotic agents in necrobiosis lipoidica.
    Acta dermato-venereologica, 1986, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Diabetes Complications; Female; Fibrinolytic Agents; Humans; Necrobiosis Lipoidic

1986
[Effect of ticlopidine on hemostasis in patients with diabetic microangiopathy].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Diabetes Complications; Diabetic Retinopathy; Female; Hemostasis; Humans; Male; M

1988
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