ticlopidine has been researched along with Coagulation Disorders, Blood in 14 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Many medications (warfarin, heparin, clopidogrel) or physiological factors (elevated International Normalized Ratio [INR], thrombocytopenia, uremia) increase the risk for bleeding." | 3.79 | The safety of thoracentesis in patients with uncorrected bleeding risk. ( Araujo, KL; Argento, AC; Murphy, TE; Pisani, MA; Puchalski, JT, 2013) |
| "Thrombosis or thromboembolism are significant concerns in companion animals and can be associated with cardiac, metabolic, neoplastic disease processes or can be one manifestation of inflammatory, infectious, and neoplastic disease conditions." | 2.48 | Antithrombotic therapy. ( Smith, SA, 2012) |
| " Nineteen out of them were treated with warfarin plus ticlopidine at a dosage enough to prolong the thrombo-test time to approximately 20% of normal value." | 1.27 | [Abnormalities of blood coagulation and effect of anticoagulant therapy in postoperative patients with lung cancer]. ( Inoue, H; Kawada, S; Koide, S; Ogawa, J; Shohtsu, A; Tsurumi, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Puchalski, JT | 1 |
| Argento, AC | 1 |
| Murphy, TE | 1 |
| Araujo, KL | 1 |
| Pisani, MA | 1 |
| Jy, W | 1 |
| Johansen, ME | 1 |
| Bidot, C | 1 |
| Horstman, LL | 1 |
| Ahn, YS | 1 |
| Nizarali, N | 1 |
| Rafique, S | 1 |
| Kawano-Castillo, J | 1 |
| Ward, E | 1 |
| Elliott, A | 1 |
| Wetzel, J | 1 |
| Hassler, A | 1 |
| McDonald, M | 1 |
| Parker, SA | 1 |
| Archeval-Lao, J | 1 |
| Tremont, C | 1 |
| Cai, C | 1 |
| Pivalizza, E | 1 |
| Rahbar, MH | 1 |
| Grotta, JC | 1 |
| Reusz, G | 1 |
| Langer, C | 1 |
| Hevessy, T | 1 |
| Csomós, Á | 1 |
| Pivalizza, EG | 1 |
| Melnikov, V | 1 |
| Guzman-Reyes, S | 1 |
| Marasigan, B | 1 |
| Batchelor, JS | 1 |
| Grayson, A | 1 |
| Smith, SA | 1 |
| Olivier, AC | 1 |
| Hollman, JL | 1 |
| Griffanti-Bartoli, F | 1 |
| Altomonte, F | 1 |
| Pitton, L | 1 |
| Armani, U | 1 |
| Piana, A | 1 |
| Ogawa, J | 1 |
| Tsurumi, T | 1 |
| Inoue, H | 2 |
| Koide, S | 1 |
| Kawada, S | 1 |
| Shohtsu, A | 1 |
| Harker, LA | 1 |
| Hatsuoka, M | 1 |
| Seiki, M | 1 |
| Sasaki, K | 1 |
| Kashii, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vacuum vs Manual Drainage During Unilateral Thoracentesis: A Randomized Trial[NCT03496987] | 100 participants (Actual) | Interventional | 2015-12-01 | Completed | |||
| Randomized, Controlled, Prospective Trial to Evaluate the Hemostatic Effect of Lyostypt® Versus Surgicel® in Arterial Bypass Anastomosis[NCT00837954] | Phase 4 | 32 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients who had procedure termination prior to complete evacuation of the pleural contents (usually as a result of refractory pain or another symptom that the patient perceived). (NCT03496987)
Timeframe: 5-20 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Manual Drainage | 1 |
| Vacuum Bottle Drainage | 8 |
"Difference in pain between pre-procedural pain and during drainage pain as measured as the difference between a pre-procedural NPSS pain score (range from 0 (no pain) to 10 (maximum pain)). This was asked again during drainage and the difference between the two was recorded. The values ranged from -10 to 10 (with a more negative number representing a decrease in pain and a more positive number representing an increase in pain)~The scale used is called The Numeric Pain Rating Scale. With ratings from 0-10. Zero is the least amount of pain experienced while 10 is the worst pain possible." (NCT03496987)
Timeframe: 5-20 minutes
| Intervention | Pre-post NPRS Pain Scale Score (Mean) |
|---|---|
| Manual Drainage | 0.53 |
| Vacuum Bottle Drainage | 1.43 |
Actual time of drainage in seconds for each patient. (NCT03496987)
Timeframe: 5-20 minutes
| Intervention | seconds (Mean) |
|---|---|
| Manual Drainage | 498.5 |
| Vacuum Bottle Drainage | 318.6 |
Volume of effusion drained (in mL) (NCT03496987)
Timeframe: <20 minutes
| Intervention | milliters (Mean) |
|---|---|
| Manual Drainage | 1023 |
| Vacuum Bottle Drainage | 1143 |
Clinical etiology of effusion (NCT03496987)
Timeframe: <7 days
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Malignant | Paramalignant | Heart Failure | Hepatic Hydrothorax | Post-Cardiothoracic Procedure | Parapneumonic | Unknown | |
| Manual Drainage | 13 | 7 | 7 | 3 | 13 | 3 | 3 |
| Vacuum Bottle Drainage | 8 | 2 | 8 | 5 | 17 | 2 | 8 |
Any complications that occur as a direct result of the procedure. We tracked patients for 7 days after the procedure to capture any complications (which is typical clinical practice) (NCT03496987)
Timeframe: <7 days
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Pneumothorax | Hemothorax | Clinically Significant Pulmonary Edema | |
| Manual Drainage | 0 | 0 | 0 |
| Vacuum Bottle Drainage | 3 | 1 | 1 |
3 reviews available for ticlopidine and Coagulation Disorders, Blood
| Article | Year |
|---|---|
A meta-analysis to determine the effect of preinjury antiplatelet agents on mortality in patients with blunt head trauma.
Topics: Aged; Anticoagulants; Aspirin; Blood Coagulation Disorders; Clopidogrel; Epidemiologic Methods; Head | 2013 |
Antithrombotic therapy.
Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation Disorders; Cat Diseases; Cats; Clopidogrel; Dog | 2012 |
Antiplatelet drugs in the management of patients with thrombotic disorders.
Topics: Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blood Coagulation Disorders; Blood Platelets | 1986 |
11 other studies available for ticlopidine and Coagulation Disorders, Blood
| Article | Year |
|---|---|
The safety of thoracentesis in patients with uncorrected bleeding risk.
Topics: Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation Disorders; Clopidogrel; Cohort Studies; D | 2013 |
Red cell-derived microparticles (RMP) as haemostatic agent.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation Disorders; Busulfan; Cell Separatio | 2013 |
Special Care Dentistry: Part 2. dental management of patients with drug-related acquired bleeding disorders.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplastic Age | 2013 |
Thrombelastography detects possible coagulation disturbance in patients with intracerebral hemorrhage with hematoma enlargement.
Topics: Aged; Blood Coagulation Disorders; Cerebral Hemorrhage; Clopidogrel; Data Interpretation, Statistica | 2014 |
[Ultrasound-guided central venous access in patients with uncorrected coagulopathy].
Topics: Adult; Aged; Anticoagulants; Blood Coagulation Disorders; Catheterization, Central Venous; Clopidogr | 2015 |
Thrombelastograph platelet mapping in a patient receiving antiplatelet therapy.
Topics: Aspirin; Blood Coagulation Disorders; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug | 2010 |
I've been taking aspirin daily for 25 years, and clopidogrel fro several years. In spite of this, I've had a number of heart attacks. You reported recently on people who can't benefit from aspirin, and I think I may be one of them. What should I do?
Topics: Aspirin; Blood Coagulation Disorders; Clopidogrel; Drug Resistance; Humans; Myocardial Infarction; P | 2004 |
Late in-stent thrombosis in a patient with systemic lupus erythematosus and hyperhomocysteinemia while on clopidogrel and aspirin.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Coagulation Disorders; Clopidogrel; Coronary Artery D | 2006 |
[Use of a new platelet aggregation inhibitor, ticlopidine, in hemodialysis].
Topics: Adult; Aged; Blood Coagulation Disorders; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged | 1979 |
[Abnormalities of blood coagulation and effect of anticoagulant therapy in postoperative patients with lung cancer].
Topics: Adult; Aged; Anticoagulants; beta-Thromboglobulin; Blood Coagulation Disorders; Female; Humans; Lung | 1986 |
Hemostatic effects of microfibrillar collagen hemostat (MCH) in experimental coagulopathy model and its mechanism of hemostasis.
Topics: Animals; Aspirin; Blood Coagulation Disorders; Cattle; Collagen; Dogs; Hemorrhage; Hemostatic Techni | 1986 |