ticlopidine has been researched along with Circulatory Collapse in 2 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Shavadia, J | 1 |
Welsh, R | 1 |
Gershlick, A | 1 |
Zheng, Y | 1 |
Huber, K | 1 |
Halvorsen, S | 1 |
Steg, PG | 1 |
Van de Werf, F | 1 |
Armstrong, PW | 1 |
Elad, S | 1 |
Chackartchi, T | 1 |
Shapira, L | 1 |
Findler, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
STREAM (Strategic Reperfusion Early After Myocardial Infarction). Comparison of the Efficacy and Safety of a Strategy of Early Fibrinolytic Treatment With Tenecteplase and Additional Antiplatelet and Antithrombin Therapy Followed by Catheterisation Within[NCT00623623] | Phase 3 | 1,899 participants (Actual) | Interventional | 2008-03-01 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
This is a key secondary endpoint. The number of observed patients with all cause death and non-fatal stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 50 |
Primary PCI (Group B) | 43 |
This is a key secondary endpoint. The number of observed patients with all cause death and shock within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 59 |
Primary PCI (Group B) | 73 |
This is a key secondary endpoint. The number of observed patients with all cause death and shock and CHF within 30 days was reported. (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 100 |
Primary PCI (Group B) | 123 |
This is a key secondary endpoint. The number of observed patients with all cause death and shock and CHF and reinfarction and disabling stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 117 |
Primary PCI (Group B) | 135 |
This is a key secondary endpoint. The number of observed patients with all cause death and shock and reinfarction within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 77 |
Primary PCI (Group B) | 85 |
This is a key secondary endpoint. The number of observed patients with all cause mortality within 30 days was reported. (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 43 |
Primary PCI (Group B) | 42 |
The number of observed patients with all-cause mortality, cardiogenic shock, congestive heart failure (CHF) and recurrent myocardial infarction within 30 days was reported for full analysis set (FAS). (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 116 |
Primary PCI (Group B) | 135 |
This is a key secondary endpoint. The number of observed patients with cardiac mortality within 30 days was reported. (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 31 |
Primary PCI (Group B) | 32 |
This is a key secondary endpoint. The number of observed patients with cardiogenic shock within 30 days was reported. (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 41 |
Primary PCI (Group B) | 56 |
This is a key secondary endpoint. The number of observed patients with congestive heart failure (CHF) within 30 days was reported. (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 57 |
Primary PCI (Group B) | 72 |
This is a key secondary endpoint. The number of observed patients with intracranial haemorrhage within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 9 |
Primary PCI (Group B) | 2 |
This is a key secondary endpoint. The number of observed patients with ischaemic stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 6 |
Primary PCI (Group B) | 3 |
This is a key secondary endpoint. The number of observed patients with major non-intracranial bleeds including blood transfusions within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 61 |
Primary PCI (Group B) | 45 |
This is a key secondary endpoint. The number of observed patients with minor non-intracranial bleeds within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 206 |
Primary PCI (Group B) | 191 |
This is a key secondary endpoint. The number of observed patients with recurrent myocardial infarction (reinfarction) within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 23 |
Primary PCI (Group B) | 21 |
This is a key secondary endpoint. The number of observed patients with rehospitalisation for cardiac reasons within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 45 |
Primary PCI (Group B) | 41 |
This is a key secondary endpoint. The number of observed patients with rehospitalisation for non-cardiac reasons within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 19 |
Primary PCI (Group B) | 11 |
This is a key secondary endpoint. The number of observed patients with serious repeat target vessel revascularization within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 1 |
Primary PCI (Group B) | 2 |
This is a key secondary endpoint. The number of observed patients with serious resuscitated ventricular fibrillation within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 32 |
Primary PCI (Group B) | 38 |
This is a key secondary endpoint. The number of observed patients with serious resuscitated ventricular fibrillation in association with invasive procedures (occurring at any time during catheterisation or urgent/elective PCI) within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 10 |
Primary PCI (Group B) | 29 |
This is a key secondary endpoint. The number of observed patients with total disabling stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 2 |
Primary PCI (Group B) | 0 |
This is a key secondary endpoint. The number of observed patients with total fatal stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 7 |
Primary PCI (Group B) | 4 |
This is a key secondary endpoint. The number of observed patients with total non-disabling stroke within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 8 |
Primary PCI (Group B) | 1 |
This is a key secondary endpoint. The number of observed patients with total non-intracranial bleeds within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 267 |
Primary PCI (Group B) | 236 |
This is a key secondary endpoint. The number of observed patients with total stroke (all types) within 30 days was reported (NCT00623623)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Tenecteplase (Group A) | 15 |
Primary PCI (Group B) | 5 |
2 other studies available for ticlopidine and Circulatory Collapse
Article | Year |
---|---|
Relationship Between Arterial Access and Outcomes in ST-Elevation Myocardial Infarction With a Pharmacoinvasive Versus Primary Percutaneous Coronary Intervention Strategy: Insights From the STrategic Reperfusion Early After Myocardial Infarction (STREAM)
Topics: Aged; Aspirin; Catheterization, Peripheral; Clopidogrel; Coronary Angiography; Enoxaparin; Female; F | 2016 |
A critically severe gingival bleeding following non-surgical periodontal treatment in patients medicated with anti-platelet.
Topics: Aspirin; Clopidogrel; Drug Combinations; Female; Gingival Hemorrhage; Humans; Middle Aged; Periodont | 2008 |