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ticlopidine and Carotid Artery Thrombosis

ticlopidine has been researched along with Carotid Artery Thrombosis in 23 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Carotid Artery Thrombosis: Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to determine if orally-administered PD0348292, a direct specific factor Xa inhibitor, inhibits thrombosis following porcine carotid arterial injury comparably to aspirin or clopidogrel alone or in combination."3.74Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. ( Baxi, S; Karnicki, K; Leadley, RJ; McBane, RD; Peterson, T; Wysokinski, W, 2008)
"The efficacy of a postoperative treatment with Low molecular weight heparin (LMWH) vs Ticlopidine in controlling early thrombosis, intimal hyperplasia and growth of true endothelial cells in small prosthetic expanded polytetrafluoroethylene (ePTFE) grafts (4 mm) interposed in the carotid artery of sheep has been evaluated."3.69Pharmacological control of intimal hyperplasia in small diameter polytetrafluoroethylene grafts. An experimental study. ( Baccini, P; Bachi, V; Ceppa, P; Civalleri, D; Decian, F; Desalvo, P; Galleano, R; Lenti, E; Simoni, G, 1996)
"Dual treatment with aspirin (5 mg kg(-1) ) and clopidogel (0."1.43A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel. ( Chu, L; Desai, K; Gutstein, DE; Kurowski, S; Seiffert, D; Wang, X; Wu, W; Zhou, X, 2016)
"Furthermore, using a carotid artery thrombosis model, these agents prolonged the time for thrombotic occlusion in mice in vivo."1.40The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. ( Espinosa, EV; Karim, ZA; Khasawneh, FT; Lin, OA; Vemana, HP, 2014)
" We evaluated apixaban, a direct and highly selective factor Xa inhibitor, in combination with clinically relevant doses of aspirin and/or clopidogrel for prevention of arterial thrombosis in rabbits."1.35Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits. ( Crain, EJ; Watson, CA; Wong, PC, 2008)
"A 70-year-old male patient with 90% stenosis of the right carotid artery and total occlusion of the left carotid artery underwent right carotid stenting."1.34Carotid artery in-stent restenosis in a patient with contralateral total occlusion, resolved with drug-eluting stenting. ( Iancu, A; Lazar, A, 2007)
"Ioxaglate's effect was associated with a reduction in TW with ioxaglate versus saline (2."1.32In vivo comparative antithrombotic effects of ioxaglate and iohexol and interaction with the platelet antiaggregant clopidogrel. ( Burnett, R; Corot, C; Idee, JM; Labarthe, B, 2003)
"To examine whether the dosage of a platelet-suppressive agent at which an antithrombotic effect is adequate and bleeding tendency is not increased can be found, the antithrombotic effects, antiplatelet effects and bleeding times of ticlopidine and aspirin were investigated in the rat experimental thrombus formation model."1.29Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model. ( Kakishita, E; Oura, Y; Suehiro, A; Ueda, M, 1994)
"Most of cerebral infarctions were observed in the hemisphere, ipsilateral to the irradiated carotid artery."1.29Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits. ( Fujimura, M; Mikashima, H, 1993)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (30.43)18.2507
2000's9 (39.13)29.6817
2010's7 (30.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spasov, AA1
Kucheryavenko, AF1
Sirotenko, VS1
Gaidukova, KA1
Morkovnik, AS1
Anisimova, VA1
Divaeva, LN1
Kuz'menko, TA1
Yi, TY1
Chen, WH1
Wu, YM1
Zhang, MF1
Lin, DL1
Lin, XH1
Lin, OA1
Karim, ZA1
Vemana, HP1
Espinosa, EV1
Khasawneh, FT1
Köklü, E2
Arslan, Ş2
Yüksel, İÖ2
Bayar, N2
Koç, P1
Zhou, X1
Kurowski, S1
Wu, W1
Desai, K1
Chu, L1
Gutstein, DE1
Seiffert, D1
Wang, X1
Wong, PC2
Watson, CA2
Crain, EJ2
Cohen, JE1
Leker, RR1
Rosenberg, S1
Arkadir, D1
Itshayek, E1
Labarthe, B1
Idee, JM1
Burnett, R1
Corot, C1
Lorrain, J1
Lechaire, I1
Gauffeny, C1
Masson, R1
Roome, N1
Herault, JP1
O'Connor, SE1
Schaeffer, P1
Herbert, JM2
Hong, TT1
Huang, J1
Driscoll, E1
Lucchesi, BR1
Hill, SL1
Brozyna, W1
Jiang, X1
Hua, J1
Bostwick, JS1
Ogletree, ML1
Schumacher, WA2
Rehfuss, R1
Iancu, A1
Lazar, A1
Hassan, AE1
Zacharatos, H1
Suri, MF1
Qureshi, AI1
Karnicki, K1
Leadley, RJ1
Baxi, S1
Peterson, T1
Wysokinski, W1
McBane, RD1
Bernat, A1
Mares, AM1
Defreyn, G1
Maffrand, JP1
Suehiro, A1
Oura, Y1
Ueda, M1
Kakishita, E1
Steinbacher, TE1
Heran, CL1
Megill, JR1
Durham, SK1
Freund, M1
Mantz, F1
Nicolini, P1
Gachet, C1
Mulvihill, J1
Meyer, L1
Beretz, A1
Cazenave, JP1
Fujimura, M1
Mikashima, H1
Simoni, G1
Galleano, R1
Civalleri, D1
Decian, F1
Desalvo, P1
Ceppa, P1
Baccini, P1
Lenti, E1
Bachi, V1
De Clerck, F1
Van Gorp, L1
Beetens, J1
Verheyen, A1
Janssen, PA1

Reviews

2 reviews available for ticlopidine and Carotid Artery Thrombosis

ArticleYear
Extensive mobile thrombus of the internal carotid artery: a case report, treatment options, and a review of the literature.
    The American surgeon, 2005, Volume: 71, Issue:10

    Topics: Anticoagulants; Carotid Artery Thrombosis; Carotid Artery, Internal; Carotid Stenosis; Cerebral Angi

2005
Drug evaluation of clopidogrel in patients with ischemic stroke.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:16

    Topics: Animals; Carotid Artery Thrombosis; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized

2007

Trials

1 trial available for ticlopidine and Carotid Artery Thrombosis

ArticleYear
Another Endovascular Therapy Strategy for Acute Tandem Occlusion: Protect-Expand-Aspiration-Revascularization-Stent (PEARS) Technique.
    World neurosurgery, 2018, Volume: 113

    Topics: Acute Disease; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Cerebral Revascul

2018

Other Studies

20 other studies available for ticlopidine and Carotid Artery Thrombosis

ArticleYear
Antithrombotic Activity of DAB-15, a Novel Diazepinobenzimidazole Compound.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Azepines; Benzimidazoles; Carotid Artery Thrombosis; Drug Ev

2017
The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adenosine Diphosphate; Animals; Antidepressive Agents; Blotting, Western; Calcium; Carotid Artery Th

2014
Acute Carotid Artery Stent Thrombosis Due to Dual Antiplatelet Resistance.
    Cardiovascular and interventional radiology, 2015, Volume: 38, Issue:4

    Topics: Acute Disease; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Clopidogrel; Drug

2015
Is Acute Carotid Artery Stent Thrombosis an Avoidable Complication?
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:10

    Topics: Aged; Aged, 80 and over; Aspirin; Carotid Artery Thrombosis; Cerebral Angiography; Clopidogrel; Fema

2015
A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:9

    Topics: Animals; Aspirin; Carotid Artery Thrombosis; Chlorides; Clopidogrel; Disease Models, Animal; Drug Ev

2016
Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:10

    Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Clopidogrel; Drug Therapy, Combination;

2008
Stent-assisted thrombolysis in acute tandem carotid and middle cerebral arteries occlusion.
    The Israel Medical Association journal : IMAJ, 2010, Volume: 12, Issue:12

    Topics: Acute Disease; Carotid Artery Thrombosis; Carotid Artery, Internal; Carotid Artery, Internal, Dissec

2010
In vivo comparative antithrombotic effects of ioxaglate and iohexol and interaction with the platelet antiaggregant clopidogrel.
    Investigative radiology, 2003, Volume: 38, Issue:1

    Topics: Animals; Carotid Artery Thrombosis; Clopidogrel; Contrast Media; Drug Synergism; Iohexol; Ioxaglic A

2003
Effects of SanOrg123781A, a synthetic hexadecasaccharide, in a mouse model of electrically induced carotid artery injury: synergism with the antiplatelet agent clopidogrel.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1

    Topics: Animals; Carotid Artery Injuries; Carotid Artery Thrombosis; Clopidogrel; Drug Synergism; Electric I

2004
The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study).
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4

    Topics: Animals; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Flow Velocity; Blood Pressure; Caro

2005
Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:5

    Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Aspirin; Biomarkers; Bleeding Time; Blood Plat

2007
Carotid artery in-stent restenosis in a patient with contralateral total occlusion, resolved with drug-eluting stenting.
    The Journal of invasive cardiology, 2007, Volume: 19, Issue:6

    Topics: Aged; Angioplasty, Balloon; Carotid Arteries; Carotid Artery Thrombosis; Carotid Stenosis; Catheteri

2007
Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:4

    Topics: Administration, Oral; Animals; Aspirin; Bleeding Time; Blood Coagulation; Carotid Artery Injuries; C

2008
Effect of various antiplatelet agents on acute arterial thrombosis in the rat.
    Thrombosis and haemostasis, 1993, Nov-15, Volume: 70, Issue:5

    Topics: Acute Disease; Amino Acid Sequence; Animals; Aspirin; Carotid Artery Thrombosis; Clopidogrel; Electr

1993
Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model.
    Research communications in chemical pathology and pharmacology, 1994, Volume: 83, Issue:2

    Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Disease Models, Animal; Male; Platelet A

1994
Effects of antithrombotic drugs in a rat model of aspirin-insensitive arterial thrombosis.
    Thrombosis and haemostasis, 1993, May-03, Volume: 69, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Animals; Aspirin; Azepines; Bridged Bicyclo Compounds, Heterocyclic

1993
Experimental thrombosis on a collagen coated arterioarterial shunt in rats: a pharmacological model to study antithrombotic agents inhibiting thrombin formation and platelet deposition.
    Thrombosis and haemostasis, 1993, May-03, Volume: 69, Issue:5

    Topics: Animals; Anticoagulants; Arterio-Arterial Fistula; Aspirin; Carotid Artery Thrombosis; Clopidogrel;

1993
Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits.
    Thrombosis research, 1993, May-01, Volume: 70, Issue:3

    Topics: Animals; Aspirin; Carotid Artery Thrombosis; Carotid Stenosis; Cerebral Infarction; Disease Models,

1993
Pharmacological control of intimal hyperplasia in small diameter polytetrafluoroethylene grafts. An experimental study.
    International angiology : a journal of the International Union of Angiology, 1996, Volume: 15, Issue:1

    Topics: Animals; Blood Vessel Prosthesis; Carotid Arteries; Carotid Artery Thrombosis; Endothelium, Vascular

1996
Arachidonic acid metabolites, ADP and thrombin modulate occlusive thrombus formation over extensive arterial injury in the rat.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1990, Volume: 1, Issue:3

    Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Coagulati

1990