Page last updated: 2024-08-16

ticlopidine and Cardiovascular Diseases

ticlopidine has been researched along with Cardiovascular Diseases in 535 studies

Research

Studies (535)

TimeframeStudies, this research(%)All Research%
pre-19903 (0.56)18.7374
1990's18 (3.36)18.2507
2000's193 (36.07)29.6817
2010's317 (59.25)24.3611
2020's4 (0.75)2.80

Authors

AuthorsStudies
Lyu, SQ; Shao, XH; Wang, J; Wu, S; Yang, YM; Zhang, H; Zhu, J1
Doran, T; Keles, EC; Kirac, D; Mihmanli, M; Yaman, AE1
Ahmad, FS; Anderson, RD; Benziger, CP; Effron, MB; Farrehi, P; Girotra, S; Gupta, K; Harrington, RA; Hernandez, AF; Jain, SK; Jones, WS; Kripalani, S; Marquis-Gravel, G; Muñoz, D; Polonsky, TS; Roe, MT; Rothman, RL; Stebbins, A; Whittle, J; Wruck, L1
Ahn, CM; Cho, DK; Cho, JY; Cho, S; Cho, YH; Choi, D; Her, AY; Hong, BK; Hong, MK; Hong, SJ; Jang, Y; Jeon, DW; Kim, BK; Kim, JS; Kim, YH; Ko, YG; Kwon, H; Nam, CM; Shin, DH; Suh, Y; Yoo, SY; Yun, KH1
Andreev, DN; Kazjulin, AN; Kochetkov, AI; Kravchenko, EV; Ostroumova, OD; Pavleeva, EE; Pereverzev, AP1
Cai, LL; Cong, YL; Deng, XL; Guan, J; Li, YR; Liu, QY; Tian, KP; Zheng, BX1
Alexopoulos, D; Davlouros, P; Deftereos, S; Goudevenos, J; Hamilos, M; Kanakakis, I; Lekakis, J; Sitafidis, G; Vavouranakis, M; Xanthopoulou, I1
Alexopoulos, D; Lekakis, J1
Ariotti, S; Baldo, A; Franzone, A; Gargiulo, G; Moschovitis, A; Piccolo, R; Santucci, A; Tumscitz, C; Valgimigli, M; Windecker, S1
Chang, S; Chang, Y; Lu, S; Sun, Q; Zhang, Y1
Bertoldi Franco, J; Buhatem Medeiros, F; Gallottini, M; Itagiba Neves, IL; Ortega, KL; Pepe Medeiros de Rezende, N; Porrio de Andrade, AC; Timerman, L1
Buckley, CE; Duconge, J; Hernandez-Suarez, DF; Lopez-Candales, A; Melin, K; Scott, SA; Tomey, MI1
Asri, S; Cham, YL; Chin, FYY; Fong, AYY; Gerunsin, J; Khiew, NZ; Koh, KT; Kong, KL; Lim, MSH; Mejin, M; Mohd Amin, NH; Ong, TK; Oon, YY; Tan, SSN; Tiong, LL; Voon, CY1
Anuwatworn, A; Kumar, V; Petrasko, M; Stys, A; Yee, J1
Baber, U; Badimon, JJ; Contreras, J; Escolar, G; Fuster, V; Linares-Koloffon, CA; Mehran, R; Rey-Mendoza, J; Sartori, S; Smith, DA; Zafar, MU1
Chen, X; Liu, Z; Ren, J; Sun, T; Wang, J; Wang, X; Zhang, J1
Byun, JK; Choi, BG; Choi, CU; Choi, SY; Kim, EJ; Kim, JB; Na, JO; Oh, DJ; Park, CG; Rha, SW; Seo, HS1
Chantzichristos, V; Giannakis, D; Kalantzi, K; Milionis, H; Papadopoulos, G; Petrou, A; Sofikitis, N; Tselepis, A; Tsoumani, M; Tzimas, P1
Bellesini, M; Donadini, MP; Middeldorp, S; Squizzato, A; Takeda, A1
Bonello, L; Frere, C; Laine, M1
Lader, E1
Bayliss, M; Fontana, V; Pirmohamed, M; Santoyo Castelazo, A; Turner, RM; Whalley, S1
Berry, C; Dawson, J; Mazlan-Kepli, W; Walters, M1
Bellesini, M; Donadini, MP; Squizzato, A1
Gremmel, T; Panzer, S; Pultar, J; Wadowski, PP1
Kioufis, S; Kokkou, E; Maniatis, K; Oikonomou, E; Papavassiliou, AG; Siasos, G; Stefanadis, C; Tousoulis, D; Zaromitidou, M1
Agewall, S; Andreotti, F; Atar, D; Cattaneo, M; Collet, JP; Grove, EL; Huber, K; Husted, S; Kjeldsen, K; Lip, GY; Morais, J; Pathak, A; Rosano, G; Storey, RF; Verheugt, FW; Wassmann, S1
Janušicová, A; Remko, M; Remková, A1
Li, J; Li, W; Liu, N; Liu, Y; Shao, H; Zhi, H1
Asai, S; Hayasaka, M; Hidaka, S; Nishida, Y; Takahashi, Y; Yoshida, Y1
Chen, J; Chen, SY; Lian, JJ; Luo, TC; Zeng, XQ1
Boyanova, D; Dandekar, T; Dittrich, M; Geiger, J; Hubertus, K; Mischnik, M; Philippi, N; Timmer, J; Wangorsch, G1
Capodanno, D; Capranzano, P1
Stiefelhagen, P2
Batista, MJ; Gomes, RV; Helmuth, B; Macedo, LA; Mesquita, ET; Villacorta Junior, H; Villacorta, AS1
Bazargan, A; Douglas, G; McKenzie, JL1
Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Seidinger, D; Steiner, S5
Polasek, TM; Sorich, MJ; Wiese, MD1
Cavallari, LH; Johnson, JA1
Roden, DM; Weeke, P2
Gerson, LB1
Chai, H; Chen, M; Huang, DJ; Li, Q; Liu, W; Luo, XL; Peng, Y; Ren, X; Wang, XQ; Zhang, C; Zhao, ZG1
Armstrong, PW; Fu, Y; Harrington, RA; James, S; Katus, H; Storey, RF; Wallentin, L; Westerhout, CM1
Grove, EL; Lordkipanidzé, M; Würtz, M1
Chang, K; Cho, JS; Chung, WS; Her, SH; Jeong, SH; Kim, CJ; Kim, PJ; Park, MW; Seung, KB; Yim, HW1
Avanzas, P; Callejo, F; Hernández-Vaquero, D; Llosa, JC; López, J; Morales, C1
Jilma, B; Siller-Matula, JM1
Goudevenos, IA; Kalantzi, KI; Tselepis, AD; Tsoumani, ME1
Biondi-Zoccai, G; Chatterjee, S; D'Ascenzo, F; DiNicolantonio, JJ; Niazi, AK; Tomek, A1
Gladding, PA1
Post, S; Wilhelm, TJ1
Moertl, D; Steiner, S1
Coory, M; Pekarsky, BA; Sorich, MJ1
Chua, D; Nishi, C1
Gus'kova, EV; Knauér, NIu; Koleda, NV; Lifshits, GI; Voronina, EN1
Fischer, C; Lümmen, G1
Burchardt, P; Danielak, D; Główka, F; Karaźniewicz-Łada, M; Komosa, A; Kruszyna, L; Lesiak, M1
Lip, G; Marìn, F; Oldgren, J; Rubboli, A1
Bae, JH; Bae, JW; Cha, MJ; Chae, IH; Cho, MC; Kim, HS; Kwon, TG; Lee, SP; Rha, SW; Suh, JW1
Andreev, DN; Dicheva, DT; Godilo-Godlevskiĭ, VA; Maev, IV; Samsonov, AA1
Chen, Y; Huang, X; Tang, Y; Xie, Y; Zhang, Y1
Brittenden, J; Ford, I; Herd, V; Mitchell, LR; Scott, NW; Williams, DJ1
Pirmohamed, M; Turner, RM1
Bliden, KP; Gurbel, PA; Jeong, YH; Shuldiner, AR; Tantry, US1
Barrios Alonso, V; del Castillo-Carnevali, H; Zamorano Gómez, JL1
Ho, HK; Ong, HY; Tan, DS; Wee, HL; Yeo, AH1
Ay, C; Gremmel, T; Koppensteiner, R; Panzer, S1
Otto, CM1
Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Steiner, S; Xhelili, E1
Akasaka, T; Arima, Y; Hokimoto, S; Kaikita, K; Mizobe, M; Nakagawa, K; Ogawa, H1
Asselbergs, FW; de Borst, GJ; de Groot, PG; Moll, FL; Roest, M; van der Graaf, Y; Wisman, PP1
Lagergren, J; Ljung, R; Lu, Y; Wang, Q1
Burchardt, P; Danielak, D; Główka, F; Karaźniewicz-Łada, M; Oszkinis, G; Rubiś, B1
Maggioni, AP1
Gurbel, PA; Hwang, JY; Hwang, SJ; Jeong, YH; Jung, JM; Kim, K; Kim, S; Koh, JS; Kwak, CH; Park, JR; Park, Y; Tantry, US1
Fernández, A; Fluixa, C; Fornós-Garrigós, A; Gil-Guillén, VF; Orozco-Beltrán, D; Puig-Barberà, J1
Blicher, TM; Hommel, K; Kamper, AL; Kristensen, SL; Madsen, M; Olesen, JB; Torp-Pedersen, C1
Daels, FP; de la Rosette, JJ; Erkan, E; Gaizauskas, A; Melekos, M; Ozgok, Y; Rioja, J; Varshney, AK1
Axelrod, D; Dzebisashvili, N; Lentine, KL; Mogal, H; Schnitzler, M; Tuttle-Newhall, JE; Williams, JM; Xiao, H1
Musunuru, K1
Galuszka, J; Hlusi, A; Hutyra, M; Indrak, K; Indrakova, J; Krcova, V; Slavik, L; Ulehlova, J1
Fleisher, LA; Patel, PA1
Chan, PS; Chen, J; Cohen, DJ; Fang, MC; Goldsweig, AM; Gosch, K; Maddox, TM; Reid, KJ; Tang, F1
Agabiti, N; Autore, C; Bauleo, L; Belleudi, V; Davoli, M; Di Martino, M; Fusco, D; Kirchmayer, U; Mayer, F; Perucci, CA; Pinnarelli, L; Ricci, R; Violini, R1
Davila, CD; Dimou, A; Figueredo, VM; Huang, KH; Monaco, T; Rangaswami, J; Vargas, F1
Huynh, K1
Kullo, IJ; Loftus, EV; Pardi, DS; Singh, S1
Patai, Á; Patai, ÁV; Solymosi, N1
Kopylov, FIu; Lomakin, OV; Mesitskaia, DF; Nikitina, IuM; Shchekochikhin, DIu1
Gargallo, CJ; Lanas, A1
Liu, J; Qi, Y; Sun, J; Wang, W; Wang, Y; Zhao, D1
Chen, L; Gong, Z; Li, H; Wang, B; Wang, J; Yang, J; Zhao, X1
Amsterdam, EA; Anderson, DR; Armstrong, EJ; Bang, H; Freischlag, JA; Laird, JR; Singh, GD; Yeo, KK1
Akasaka, T; Arima, Y; Hokimoto, S; Kaikita, K; Kumagae, N; Morita, K; Nakagawa, K; Ogawa, H; Oniki, K; Sakamoto, K; Tabata, N; Tsujita, K; Yamamoto, E1
Farkouh, ME; Pereira, NL; Rihal, CS; Sargent, DJ1
Huffman, MD; Kishore, SP; Patel, A; Vedanthan, R; Vidula, M1
Aksenova, MG; Dobrovol'skiĭ, AV; Kirillov, MIu; Kopylov, FIu; Mesitskaia, DF; Nikitina, IuM; Syrkin, AL1
Capranzano, P; Castiglioni, B1
Hulot, JS; Lewis, JP; Scott, SA; Yang, Y1
Bouatou, Y; Daali, Y; Desmeules, J; Fontana, P; Samer, CF1
Frelinger, AL; Gremmel, T; Michelson, AD1
Khatri, S; Pierce, T1
Angiolillo, DJ; Gaudio, C; Greco, C; Marazzi, G; Pelliccia, F; Rollini, F1
Asher, E; Atar, S; Beigel, R; Fefer, P; Hammerman, H; Herscovici, R; Matetzky, S; Mazin, I; Polak, A; Regev, E; Sabbag, A; Shlomo, N; Zahger, D1
Chandrasekhar, J; Froeschl, M; Hibbert, B; May, ML; Mehran, R; So, D1
Choi, JL; Goh, RY; Guo, LZ; Han, JY; Kim, BR; Kim, MH; Li, S; Woo, KS1
Ahmed, O; Daniel, E; Grunwald, JE; Maguire, MG; Martin, DF; Ying, GS1
Alessi, MC; Angiolillo, DJ; Aradi, D; Beigel, R; Berdagué, P; Campo, G; Combescure, C; Cuisset, T; Fontana, P; Gawaz, M; Geisler, T; Gori, AM; Gurbel, PA; Hochholzer, W; Janssen, PW; Marcucci, R; Neumann, FJ; Reny, JL; Ten Berg, J; Yong, G1
Dobesh, PP; Doyle, M; Varnado, S1
Bell, DS1
Boost, KA; Gandorfer, A; Haritoglou, C; Heinicke, N; Hintschich, C; Huebert, I; Kampik, A; Kook, D; Mayer, WJ; Miller, CV; Wolf, A1
Al-Mesallamy, HO; El-Hammady, WA; Gong, Y; Hamdy, NM; Hammad, LN; Johnson, JA; Khalil, BM; Langaee, T; Schaalan, MF; Shahin, MH; Solayman, MH1
Bolek, T; Fedor, M; Galajda, P; Kovář, F; Kubisz, P; Mokáň, M; Samoš, M1
Berger, JS; Smilowitz, NR1
Cavallari, LH; Mason, DL1
Ayub, A; Hamid, S; Jafri, W; Khan, AH; Murtaza, D; Naeem, B; Parkash, O1
Chen, J; Hu, XW; Li, CJ; Li, JM; Xu, K; Xu, L; Zhang, SH; Zhu, H1
Bourdakis, A; Charmpas, C; Christogiannis, Z; Dimoulis, N; Draganigos, A; Efthimiadis, I; Giannakoulas, G; Giatrakos, I; Giogiakas, V; Goudevenos, JA; Goumas, G; Hatziathanasiou, G; Kalantzi, KI; Kazakos, E; Kipouridis, N; Konstantinou, S; Milionis, H; Nikolopoulos, D; Ntalas, IV; Panagiotakos, DB; Peltekis, L; Prokopakis, N; Sinteles, I; Stroumbis, C; Terzoudi, K; Thoma, M; Tselepis, AD; Tsilias, K; Tsoumani, ME; Vakalis, I; Vardakis, K; Vasilakopoulos, V; Vemmos, K; Voukelatou, M; Xaraktsis, I1
Dillinger, JG; Drouet, L; Henry, P; Saeed, A; Sideris, G; Silberman, SM; Sollier, CB; Spagnoli, V; Voicu, S1
Bansilal, S; Becker, RC; Cannon, CP; Harrington, RA; Himmelmann, A; Husted, S; James, SK; Katus, HA; Lopes, RD; Neely, B; Shimada, YJ; Steg, PG; Storey, RF; Wallentin, L; Wiviott, SD1
Lordkipanidzé, M; So, D; Tanguay, JF1
García Rodríguez, LA; Hennekens, CH; Lanas, A; Martín-Pérez, M; Rothwell, PM1
Sasaki, K; Ueno, T1
Cavallari, LH; Duarte, JD1
Grove, EL; Würtz, M2
Kiss, RG1
El Amri, H; Zaiou, M1
Baker, BA; Cohen, DJ; Effron, MB; Faries, DE; Jackson, LR; Ju, C; McCoy, LA; Messenger, JC; Peterson, ED; Wang, TY; Zettler, M1
Baber, U; Dangas, GD; Giustino, G; Guimarães, AH; Hemmrich, M; Mehran, R; Thomitzek, K; Tijssen, J; Valgimigli, M; van Es, GA; Volkl, AA; Vranckx, P; Welsh, RC; Wildgoose, P; Windecker, S; Zazula, A1
García Rodríguez, LA; González-Pérez, A; Johansson, S; Nagy, P; Sáez, ME1
Baumgartner, I; Berger, JS; Blomster, J; Fowkes, FG; Heizer, G; Held, P; Hiatt, WR; Jones, WS; Katona, BG; Mahaffey, KW; Millegård, M; Norgren, L; Patel, MR; Reist, C1
Anstrom, KJ; Baker, BA; Cohen, DJ; Effron, MB; Henry, TD; McCoy, LA; Messenger, JC; Peterson, ED; Wang, TY; Zettler, ME1
Bhurtu, A; Bundhun, PK; Huang, WQ; Teeluck, AR1
Artesiani, ML; Bazzoli, F; Eusebi, LH; Gelli, D; Montagnani, M; Rabitti, S; Zagari, RM1
Fort, JG; Han, Y; Schofield, D; Tursi, JP; Zhang, W1
Monte, SV; Norgard, NB1
Amarshi, N; Sullivan, J1
Alberts, MJ; Hanley, DF; Serebruany, VL1
Talbert, RL1
Petty, DR; Silcock, J1
Barillà, F; Donato, L; Petrini, N; Pulcinelli, FM; Riondino, S; Tanzilli, G; Torromeo, C1
Dieplinger, B; Haltmayer, M; Mueller, T; Poelz, W1
Bond, SP; Buerke, M; Faerber, J; Maegdefessel, L; Messow, CM; Muenzel, T; Raaz, U; Schlitt, A; Weiss, C; Werdan, K1
Butler, KL; Fortuna, GR; James, LE; Mueller, EW; Shutter, LA1
Ang, L; Bromberg-Marin, G; Clopton, P; Idrees, Z; Keramati, S; Khalid, A; Mahmud, E; Palakodeti, V; Tran, P; Tsimikas, S; Zafar, N1
Rokkas, CK; Tourmousoglou, CE1
Erdmann, E; Müller-Ehmsen, J1
Eikelboom, JW; Hirsh, J; Raju, NC1
Bonello, L; De Labriolle, A; Kent, KM; Lemesle, G; Lindsay, J; Pichard, AD; Pinto Slottow, TL; Roy, P; Satler, LF; Steinberg, DH; Suddath, WO; Torguson, R; Waksman, R; Xue, Z1
de Moerloose, P; Fontana, P; Reny, JL1
Lurie, F; Wong, DK; Wong, LL1
Angiolillo, DJ; Bass, TA; Capranzano, P; Guzman, LA; Suryadevara, S; Zenni, MZ1
Antman, EM; Brandt, JT; Braunwald, E; Close, SL; Hockett, RD; Macias, W; Mega, JL; Sabatine, MS; Shen, L; Walker, JR; Wiviott, SD1
Kopyleva, O; Serebruany, V; Shalito, I1
Calatzis, A1
Curzen, N; Hobson, A1
Bhatt, DL; Cacoub, PP; Creager, MA; Steg, PG; Topol, EJ1
Akram, F; Akram, S; Postuła, M1
Freedman, JE; Hylek, EM1
Campbell, CL; Oestreich, JH; Smyth, SS1
Fowler, A; Nappi, JM; Pallares, MJ; Powers, ER; Reeves, R; Zwerner, PL1
Bonello, L; De Labriolle, A; Kent, KM; Lemesle, G; Pichard, AD; Roy, P; Satler, LF; Steinberg, DH; Suddath, WO; Torguson, R; Waksman, R1
Milani, RV1
Schwartz, LM; Welch, HG; Woloshin, S1
Siasos, G; Stefanadis, C; Tousoulis, D2
Berger, PB; Bhatt, DL; Brennan, DM; Eikelboom, JW; Hankey, GJ; Montalescot, G; Steinhubl, SR; Topol, EJ1
Conti, CR1
Gawaz, M; Giannitsis, E; Ibrahim, H; Ivandic, BT; Katus, HA; Sausemuth, M1
Berger, PB; Bhatt, DL; Dasgupta, A; Dimas, AP; Fox, KA; Haffner, SM; Mak, KH; Montalescot, G; Shao, M; Steg, PG; Steinhubl, SR; Topol, EJ; Weber, MA1
Fox, SC; Heptinstall, S; May, JA; Neubert, U; Shah, A1
Apostolakis, S; Lip, GY; Shantsila, E1
Bass, TA1
Batyraliev, TA; Fettser, DV; Pataraia, SA; Preobrazhenskiĭ, DV; Sidorenko, BA1
Alessi, MC; Bali, L; Bonnet, JL; Cuisset, T; Frere, C; Lambert, M; Morange, PE; Moro, PJ; Mouret, JP; Quilici, J1
Broekman, MJ; Fung, CY; Mahaut-Smith, MP; Marcus, AJ1
Cohen, M1
Bhatt, DL; Caro, JJ; Chen, J; Cohen, DJ; Dunn, ES; Gabriel, S; Jackson, JD; Mahoney, EM; Shi, C; Topol, EJ1
Hoppe, UC1
Gomes, T; Juurlink, DN; Mamdani, MM1
Spinler, SA1
Antonino, MJ; Gurbel, PA; Tantry, US1
Hödl, R; Kainz, J; Metzler, H; Münch, A; Primus, G; Prüller, F; Rehak, P1
Elalamy, I; Samama, MM1
Cheng, WJ; Guo, YH; Li, YP; Liu, T; Liu, YY; Ma, HY; Shi, DM; Xie, Y; Zhao, YX; Zhou, YJ1
Hayden, EC1
Alberts, P; Bounameaux, H; Fontana, P; Mann, J; Sakariassen, KS; Sorensen, AS1
Antman, EM; Bates, ER; Braunwald, E; Close, SL; Hautvast, RW; Mega, JL; Michelson, AD; Murphy, SA; O'Donoghue, ML; Rozenman, Y; Sabatine, MS; Shen, L; Ver Lee, PN; Wiviott, SD1
Hessen, SE; Joy, PS; Karalis, DG; Nkonde, C; Watson, PD1
Hankey, GJ; Mason, G; Maurice, JB; Sudlow, CL; Wedderburn, CJ1
Chang, PY; Chen, PF; Hsiao, FY; Huang, WF; Kuo, KN; Tsai, YW; Wen, YW1
Avsar, O; Batyraliev, TA; Islek, M; Preobrazhenskiĭ, DV; Sidorenko, BA; Vural, A1
Antonino, MJ; Bliden, KP; Gurbel, PA; Singla, A; Tantry, US1
Chen, CP; Seet, RC1
Helft, G1
Hennekens, C; Laine, L1
Berger, JS; Berger, PB; Bhatt, DL; Cannon, CP; Chen, Z; Jiang, L; Jones, JB; Mehta, SR; Sabatine, MS; Steinhubl, SR; Topol, EJ1
Faxon, DP1
Last, EJ; Sheehan, AH1
Avorn, J; Choudhry, NK; Rassen, JA; Schneeweiss, S1
Berger, JS; Berger, PB; Bhatt, DL; Fox, KA; Hacke, W; Lincoff, AM; Montalescot, G; Shao, M; Steg, PG; Steinhubl, SR; Topol, EJ1
Kremneva, LV; Shalaev, SV1
Lanas, A1
Grove, EL; Storey, RF1
Spectre, G; Varon, D1
Avsar, O; Batyraliev, TA; Fettser, DV; Islek, M; Preobrazhenskiĭ, DV; Sidorenko, BA; Vural, A1
Shai, E; Spectre, G; Varon, D1
Kwok, CS; Loke, YK1
Hasford, J; Lehmacher, W1
Anderson, SD; Epstein, BJ; Shah, NK; Yim, J1
Abbate, R; Gensini, GF; Giusti, B; Gori, AM; Marcucci, R; Sofi, F2
Chong, BH; Gemmell, R; Kidson-Gerber, G; Prasan, AM; Weaver, J1
Barazer, I; Berdague, P; Combescure, C; Fabbro-Peray, P; Fontana, P; Gris, JC; Labruyere, C; Laporte, S; Mallouk, N; Reny, JL1
Campo, G; Cangiano, E; Cavazza, C; Ferrari, R; Fileti, L; Marchesini, J; Tebaldi, M; Valgimigli, M1
Bramlage, P; Einhäupl, K; Hasford, J; Koch, G; Lehmacher, W; Rothwell, PM1
Böhm, M; Dichgans, M; Diener, HC; Endres, M; Grond, M; Hacke, W; Hoppe, UC; Kirchhof, P; Laufs, U; Meinertz, T; Ringelstein, EB; Rosenkranz, S; Röther, J1
Jezovnik, MK; Poredos, P1
Chung, CP; Daugherty, JR; Griffin, MR; Hall, K; Kaltenbach, LA; Murray, KT; Ray, WA; Smalley, WE; Stein, CM1
Griswold, ME; Localio, AR; Mulrow, C1
Gebel, JM1
Gladding, P; Webster, M; White, H1
Carroll, NM; DeFor, TA; Go, AS; Ho, PM; Jackevicius, C; Maddox, TM; Magid, DJ; Margolis, KL; Powers, JD; Rumsfeld, JS; Tsai, TT1
Gasparyan, AY1
Eikelboom, JW; Sobieraj-Teague, M1
Mourad, JJ1
Alessi, MC; Cuisset, T; Dutour, A; Frère, C; Gaborit, B1
Kummer, O; Mach, F; Marti, G; Roffi, M1
Dehmer, GJ; Holmes, DR; Kaul, S; Leifer, D; O'Gara, PT; Stein, CM1
Alegre-del Rey, EJ; Castaño-Lara, R; Díaz-Alersi, R; Sierra-Sánchez, J1
Leibundgut, G; Tsimikas, S1
Bareiss, P; Chauvin, M; El Ghannudi, S; Gachet, C; Meyer, N; Morel, O; Ohlmann, P; Radulescu, B; Wiesel, ML1
Aboyans, V; Lacroix, P; Le Guyader, A1
Aubert, R; Breall, JA; Desta, Z; Epstein, RS; Flockhart, DA; Frueh, FW; Kreutz, RP; Skaar, TC; Stanek, EJ; Teagarden, JR; Yao, J1
Aichele, S; Bigalke, B; Fateh-Moghadam, S; Flather, M; Gawaz, M; Geisler, T; Herkommer, M; Htun, P; May, AE; Müller, K; Stellos, K1
Hagenaars, MP; Siersema, PD; Smout, AJ; van Boxel, OS; van Oijen, MG1
Curtin, RJ; Dineen, PF; Harty, JA1
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Bennett, JS1
Ellis, SG; Lincoff, AM; Steinhubl, SR; Topol, EJ; Wolski, K1
Plehn, JF; Solet, DJ; Zacharski, LR1
Chrolavicius, S; Fox, KK; Mehta, SR; Tognoni, G; Yusuf, S; Zhao, F1
Owen, A1
Cohn, PF1
Boissel, JP; Destors, JM; Peyrieux, JC1
Harker, LA1

Reviews

192 review(s) available for ticlopidine and Cardiovascular Diseases

ArticleYear
[The relationship between the combined use of various proton pump inhibitors with antiplatelet drugs and the risk of cardiovascular complications].
    Terapevticheskii arkhiv, 2019, Aug-15, Volume: 91, Issue:8

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome

2019
The Efficacy and Safety of 3 Types of Interventions for Stroke Prevention in Patients With Cardiovascular and Cerebrovascular Diseases: A Network Meta-analysis.
    Clinical therapeutics, 2017, Volume: 39, Issue:7

    Topics: Anticoagulants; Aspirin; Bayes Theorem; Cardiovascular Diseases; Clopidogrel; Dabigatran; Dipyridamole; Hemorrhage; Humans; Odds Ratio; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Thiazoles; Ticlopidine; Treatment Outcome; Warfarin

2017
A Primer on Bleeding Risk and Management Strategies of Newer Oral Anti Platelet Agents in Cardiovascular Disease.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2016, Volume: 69, Issue:10

    Topics: Adenosine; Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Thrombosis; Ticagrelor; Ticlopidine

2016
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events.
    The Cochrane database of systematic reviews, 2017, 12-14, Volume: 12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2017
Oral antiplatelet agents in cardiovascular disease.
    VASA. Zeitschrift fur Gefasskrankheiten, 2019, Volume: 48, Issue:4

    Topics: Adenosine; Administration, Oral; Cardiovascular Diseases; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticlopidine

2019
Expert position paper on the use of proton pump inhibitors in patients with cardiovascular disease and antithrombotic therapy.
    European heart journal, 2013, Volume: 34, Issue:23

    Topics: Adenosine; Aspirin; Benzimidazoles; beta-Alanine; Cardiovascular Diseases; Clopidogrel; Dabigatran; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine; Warfarin

2013
Pharmacodynamic impacts of proton pump inhibitors on the efficacy of clopidogrel in vivo--a systematic review.
    Clinical cardiology, 2013, Volume: 36, Issue:4

    Topics: Adenosine Diphosphate; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Resistance; Gastrointestinal Diseases; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Receptors, Purinergic P2Y12; Ticlopidine

2013
Dual antiplatelet therapy in patients with diabetes mellitus: special considerations.
    Expert review of cardiovascular therapy, 2013, Volume: 11, Issue:3

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2013
Perioperative management of anticoagulation in elective surgery.
    ANZ journal of surgery, 2013, Volume: 83, Issue:11

    Topics: Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Cardiovascular Diseases; Clopidogrel; Dabigatran; Elective Surgical Procedures; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Assessment; Thromboembolism; Ticlopidine; Withholding Treatment

2013
Challenges and limitations in the interpretation of systematic reviews: making sense of clopidogrel and CYP2C19 pharmacogenetics.
    Clinical pharmacology and therapeutics, 2013, Volume: 94, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Cytochrome P-450 CYP2C19; Endpoint Determination; Genotype; Humans; Meta-Analysis as Topic; Models, Statistical; Patient Selection; Platelet Aggregation Inhibitors; Publication Bias; Research Design; Review Literature as Topic; Ticlopidine

2013
Pharmacogenetics and cardiovascular disease--implications for personalized medicine.
    Pharmacological reviews, 2013, Volume: 65, Issue:3

    Topics: Animals; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cardiovascular Agents; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Mixed Function Oxygenases; Organic Anion Transporters; Patient Selection; Pharmacogenetics; Phenotype; Platelet Aggregation Inhibitors; Precision Medicine; Risk Assessment; Risk Factors; Ticlopidine; Vitamin K Epoxide Reductases; Warfarin

2013
Pharmacogenomics and cardiovascular disease.
    Current cardiology reports, 2013, Volume: 15, Issue:7

    Topics: Adrenergic beta-Antagonists; Cardiovascular Agents; Cardiovascular Diseases; Clopidogrel; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Polymorphism, Genetic; Practice Guidelines as Topic; Ticlopidine; Warfarin

2013
Proton pump inhibitors and potential interactions with clopidogrel: an update.
    Current gastroenterology reports, 2013, Volume: 15, Issue:6

    Topics: Cardiovascular Diseases; Clopidogrel; Confounding Factors, Epidemiologic; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2013
The impact of smoking on clinical efficacy and pharmacodynamic effects of clopidogrel: a systematic review and meta-analysis.
    Heart (British Cardiac Society), 2014, Volume: 100, Issue:3

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Smoking; Ticlopidine; Treatment Outcome

2014
Clopidogrel generic formulations in the era of new antiplatelets: a systematic review.
    Current vascular pharmacology, 2014, Volume: 12, Issue:5

    Topics: Animals; Cardiovascular Diseases; Chemistry, Pharmaceutical; Clinical Trials as Topic; Clopidogrel; Drugs, Generic; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2014
[The most important aspects of risk assessment].
    Zentralblatt fur Chirurgie, 2013, Volume: 138, Issue:3

    Topics: Algorithms; Aspirin; Cardiovascular Diseases; Clopidogrel; Digestive System Surgical Procedures; Drug Substitution; Drug Therapy, Combination; Health Status Indicators; Hemorrhage; Heparin; Humans; Perioperative Period; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Thromboembolism; Ticlopidine; Viscera

2013
Platelet reactivity tests for assessing antiplatelet drug response: what the clinician needs to know.
    Expert review of cardiovascular therapy, 2013, Volume: 11, Issue:8

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Humans; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Precision Medicine; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2013
New antiplatelet agents for cardiovascular disease.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, Nov-05, Volume: 185, Issue:16

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2013
Applied pharmacogenomics in cardiovascular medicine.
    Annual review of medicine, 2014, Volume: 65

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Antithrombins; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; Precision Medicine; Ticlopidine; Vitamin K Epoxide Reductases; Warfarin

2014
Combination of a new oral anticoagulant, aspirin and clopidogrel after acute coronary syndrome: new therapeutic standard?
    Internal and emergency medicine, 2013, Volume: 8, Issue:8

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Combinations; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2013
[Drug interaction of proton pump inhibitors and clopidogrel taken together].
    Klinicheskaia meditsina, 2013, Volume: 91, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2013
High-maintenance-dose clopidogrel in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Endpoint Determination; Humans; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2013
Cardiovascular pharmacogenomics: expectations and practical benefits.
    Clinical pharmacology and therapeutics, 2014, Volume: 95, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Anticoagulants; Cardiovascular Diseases; Clopidogrel; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pharmacogenetics; Platelet Aggregation Inhibitors; Renin-Angiotensin System; Ticlopidine; Warfarin

2014
[Antiplatelet therapy: resistance to traditional antiaggregation drugs and role of new antiplatelet agents].
    Medicina clinica, 2014, Sep-09, Volume: 143, Issue:5

    Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine

2014
Platelet-reactivity tests identify patients at risk of secondary cardiovascular events: a systematic review and meta-analysis.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:5

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticlopidine

2014
Personalized genomes and cardiovascular disease.
    Cold Spring Harbor perspectives in medicine, 2014, Sep-25, Volume: 5, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Genome-Wide Association Study; Genome, Human; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pharmacogenetics; Platelet Aggregation Inhibitors; Precision Medicine; Risk Assessment; Ticlopidine

2014
Aspirin, clopidogrel, and the surgeon.
    Advances in surgery, 2014, Volume: 48

    Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Practice Guidelines as Topic; Preoperative Care; Risk Assessment; Thienopyridines; Ticlopidine; Time Factors; Withholding Treatment

2014
Epidemiology, risk factors and management of cardiovascular diseases in IBD.
    Nature reviews. Gastroenterology & hepatology, 2015, Volume: 12, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammatory Bowel Diseases; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2015
Management of low-dose aspirin and clopidogrel in clinical practice: a gastrointestinal perspective.
    Journal of gastroenterology, 2015, Volume: 50, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine

2015
Genotype-based clinical trials in cardiovascular disease.
    Nature reviews. Cardiology, 2015, Volume: 12, Issue:8

    Topics: Adrenergic beta-Antagonists; Anticoagulants; Biomarkers; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Forecasting; Genetic Markers; Genomics; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pharmacogenetics; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Sequence Analysis, DNA; Ticlopidine; Warfarin

2015
Building the Case for Clopidogrel as a World Health Organization Essential Medicine.
    Circulation. Cardiovascular quality and outcomes, 2015, Volume: 8, Issue:4

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Utilization; Drugs, Essential; Health Policy; Humans; Platelet Aggregation Inhibitors; Public Health; Ticlopidine; World Health Organization

2015
The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19.
    Expert opinion on drug metabolism & toxicology, 2015, Volume: 11, Issue:10

    Topics: Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Ticlopidine

2015
Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review.
    Current drug metabolism, 2015, Volume: 16, Issue:2

    Topics: Adenosine; Animals; Cardiovascular Diseases; Clopidogrel; Humans; Kidney Failure, Chronic; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2015
Drug-drug interactions between clopidogrel and novel cardiovascular drugs.
    European journal of pharmacology, 2015, Oct-15, Volume: 765

    Topics: Animals; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Ticlopidine

2015
The impact of switching P2Y12 receptor inhibitor therapy during index hospitalization: a systematic review.
    European journal of clinical pharmacology, 2016, Volume: 72, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Hemorrhage; Hospitalization; Humans; Purinergic P2Y Receptor Antagonists; Ticlopidine

2016
Vascular risk levels affect the predictive value of platelet reactivity for the occurrence of MACE in patients on clopidogrel. Systematic review and meta-analysis of individual patient data.
    Thrombosis and haemostasis, 2016, Volume: 115, Issue:4

    Topics: Age Factors; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Risk; Ticlopidine

2016
Antiplatelet Agents in Cardiology: A Report on Aspirin, Clopidogrel, Prasugrel, and Ticagrelor.
    Current pharmaceutical design, 2016, Volume: 22, Issue:13

    Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticagrelor; Ticlopidine; Transcatheter Aortic Valve Replacement

2016
Type 2 Diabetes and ADP Receptor Blocker Therapy.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Adenosine; Adenosine Monophosphate; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome

2016
Perioperative Management to Reduce Cardiovascular Events.
    Circulation, 2016, Mar-15, Volume: 133, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Anesthesia; Anticoagulants; Arthroplasty, Replacement, Knee; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Contraindications; Coronary Disease; Disease Susceptibility; Heparin, Low-Molecular-Weight; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Perioperative Care; Postoperative Complications; Postoperative Hemorrhage; Preanesthetic Medication; Risk Factors; Risk Reduction Behavior; Stress, Physiological; Surgical Procedures, Operative; Thrombophilia; Ticlopidine

2016
Cardiovascular Pharmacogenomics--Implications for Patients With CKD.
    Advances in chronic kidney disease, 2016, Volume: 23, Issue:2

    Topics: Adrenergic beta-Antagonists; Anticoagulants; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Pharmacogenetics; Phenotype; Platelet Aggregation Inhibitors; Precision Medicine; Purinergic P2Y Receptor Antagonists; Renal Insufficiency, Chronic; Solute Carrier Proteins; Ticlopidine; Vitamin K Epoxide Reductases; Warfarin

2016
Intensified Antiplatelet Treatment Reduces Major Cardiac Events in Patients with Clopidogrel Low Response: A Meta-analysis of Randomized Controlled Trials.
    Chinese medical journal, 2016, Apr-20, Volume: 129, Issue:8

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine

2016
Platelet function testing as a biomarker for efficacy of antiplatelet drugs.
    Biomarkers in medicine, 2016, Volume: 10, Issue:8

    Topics: Biomarkers; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Purinergic P2Y Receptor Antagonists; Ticlopidine

2016
Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Databases, Factual; Gastrointestinal Hemorrhage; Humans; Incidence; Intracranial Hemorrhages; Observational Studies as Topic; Odds Ratio; Risk; Ticlopidine

2016
Proton Pump Inhibitors in Cardiovascular Disease: Drug Interactions with Antiplatelet Drugs.
    Advances in experimental medicine and biology, 2017, Volume: 906

    Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Dosage Calculations; Drug Interactions; Esomeprazole; Gastrointestinal Hemorrhage; Gene Expression; Humans; Hydrogen-Ion Concentration; Peptic Ulcer; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine

2017
[Direct oral anticoagulants in cardiology].
    Orvosi hetilap, 2016, Volume: 157, Issue:38

    Topics: Administration, Oral; Anticoagulants; Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Heparin; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin

2016
Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.
    Clinical genetics, 2017, Volume: 91, Issue:3

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Genetic Predisposition to Disease; Genetic Variation; Genome, Human; Genomics; Humans; Pharmacogenetics; Precision Medicine; Ticlopidine; Warfarin

2017
Is the concomitant use of clopidogrel and Proton Pump Inhibitors still associated with increased adverse cardiovascular outcomes following coronary angioplasty?: a systematic review and meta-analysis of recently published studies (2012 - 2016).
    BMC cardiovascular disorders, 2017, 01-05, Volume: 17, Issue:1

    Topics: Aged; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Drug Interactions; Female; Humans; Male; Middle Aged; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2017
Proton pump inhibitors: Risks of long-term use.
    Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:7

    Topics: Calcium; Cardiovascular Diseases; Clopidogrel; Dementia; Drug Interactions; Fractures, Bone; Gastrointestinal Neoplasms; Humans; Intestinal Absorption; Kidney Diseases; Pneumonia; Proton Pump Inhibitors; Risk; Ticlopidine; Time Factors; Vitamins

2017
Obesity and Inflammation and Altered Clopidogrel Pharmacokinetics and Pharmacodynamics.
    Drug metabolism letters, 2017, 11-17, Volume: 11, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Inflammation; Obesity; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2017
Dual antiplatelet therapy with clopidogrel and aspirin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Jun-15, Volume: 65, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Contraindications; Coronary Artery Bypass; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Polypharmacy; Ticlopidine

2008
Clopidogrel and aspirin in cardiovascular medicine: responders or not--current best available evidence.
    Cardiovascular & hematological agents in medicinal chemistry, 2008, Volume: 6, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2008
Platelet ADP-receptor antagonists for cardiovascular disease: past, present and future.
    Nature clinical practice. Cardiovascular medicine, 2008, Volume: 5, Issue:12

    Topics: Adenosine; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; History, 20th Century; History, 21st Century; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2008
Antiplatelet drug response variability and the role of platelet function testing: a practical guide for interventional cardiologists.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Jan-01, Volume: 73, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial Ischemia; Patient Compliance; Patient Selection; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Practice Guidelines as Topic; Predictive Value of Tests; Recurrence; Risk Assessment; Stents; Ticlopidine; Treatment Failure; Treatment Outcome

2009
PPI interactions with clopidogrel.
    The Medical letter on drugs and therapeutics, 2009, Jan-12, Volume: 51, Issue:1303

    Topics: Anti-Ulcer Agents; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastroesophageal Reflux; Humans; Incidence; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Stents; Ticlopidine

2009
Prasugrel development - claims and achievements.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:1

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Administration Schedule; Drug Discovery; Drug Resistance; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Research Design; Risk Assessment; Stents; Thiophenes; Ticlopidine; Treatment Outcome

2009
Current problems, new opportunities and future directions of anti-platelet therapy - increasing role of novel antiplatelet agents in cardiovascular diseases.
    Recent patents on cardiovascular drug discovery, 2009, Volume: 4, Issue:1

    Topics: Adenosine; Adenosine Monophosphate; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Imines; Lactones; Patents as Topic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, PAR-1; Receptors, Purinergic P2Y12; Receptors, Thrombin; Thiophenes; Ticagrelor; Ticlopidine

2009
Antiplatelet therapy after endovascular intervention: does combination therapy really work and what is the optimum duration of therapy?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Jul-01, Volume: 74 Suppl 1

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Graft Occlusion, Vascular; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency

2009
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part I. Ticlopidine].
    Kardiologiia, 2009, Volume: 49, Issue:4

    Topics: Cardiovascular Diseases; Humans; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Treatment Outcome

2009
P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic window.
    Trends in cardiovascular medicine, 2009, Volume: 19, Issue:1

    Topics: Adenosine Triphosphate; Antigens, CD; Apyrase; Aspirin; Biomedical Research; Cardiovascular Diseases; Cerebral Hemorrhage; Clinical Trials as Topic; Clopidogrel; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Endothelium, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2009
Antiplatelet therapy in percutaneous coronary intervention: a critical review of the 2007 AHA/ACC/SCAI guidelines and beyond.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Oct-01, Volume: 74, Issue:4

    Topics: American Heart Association; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Evidence-Based Medicine; Humans; Medication Adherence; Metals; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Prosthesis Design; Risk Assessment; Stents; Ticlopidine; Treatment Outcome; United States

2009
Safety and tolerability of antiplatelet therapies for the secondary prevention of atherothrombotic disease.
    Pharmacotherapy, 2009, Volume: 29, Issue:7

    Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2009
Recent developments in clopidogrel pharmacology and their relation to clinical outcomes.
    Expert opinion on drug metabolism & toxicology, 2009, Volume: 5, Issue:8

    Topics: Animals; Body Weight; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2009
[Study of variability in response to aspirin and clopidogrel: clinical and/or biological resistance?].
    Annales pharmaceutiques francaises, 2009, Volume: 67, Issue:4

    Topics: Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2009
Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases.
    Future cardiology, 2009, Volume: 5, Issue:5

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Humans; Kidney Diseases; Platelet Aggregation Inhibitors; Proteinuria; Receptors, Thrombin; Thrombosis; Thromboxane A2; Thromboxane-A Synthase; Ticlopidine

2009
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials.
    Lancet (London, England), 2009, Sep-19, Volume: 374, Issue:9694

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Proton Pump Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticlopidine; Treatment Outcome

2009
Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients.
    The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine

2009
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part II. Clinical pharmacology of clopidogrel].
    Kardiologiia, 2009, Volume: 49, Issue:10

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Treatment Outcome

2009
Optimizing antiplatelet therapy in high-risk patients with atrial fibrillation: insights from Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE A).
    Stroke, 2009, Volume: 40, Issue:12

    Topics: Antihypertensive Agents; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Contraindications; Humans; Irbesartan; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Tetrazoles; Ticlopidine; Treatment Outcome

2009
[Long-term use of oral antiplatelet therapy: from studies to practice].
    Presse medicale (Paris, France : 1983), 2010, Volume: 39, Issue:4

    Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine

2010
Proton pump inhibitor and clopidogrel interaction: fact or fiction?
    The American journal of gastroenterology, 2010, Volume: 105, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine

2010
The relative efficacy and safety of clopidogrel in women and men a sex-specific collaborative meta-analysis.
    Journal of the American College of Cardiology, 2009, Nov-17, Volume: 54, Issue:21

    Topics: Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Prevalence; Secondary Prevention; Sex Distribution; Sex Factors; Ticlopidine; Treatment Outcome

2009
Review of recent evidence: potential interaction between clopidogrel and proton pump inhibitors.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Dec-01, Volume: 66, Issue:23

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk; Ticlopidine; Time Factors

2009
[Acute coronary syndrome in patients with carbohydrate metabolic disturbances (a review)].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:10

    Topics: Acute Coronary Syndrome; Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2009
Antiplatelet agents.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistance; Drug Therapy, Combination; Forecasting; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine

2009
[Thienopyridines in the treatment and prevention of cardiovascular diseases. III. therapeutic application of clopidogrel as monotherapy (without acetylsalicylic acid)].
    Kardiologiia, 2009, Volume: 49, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Ticlopidine; Ulcer

2009
Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel.
    Alimentary pharmacology & therapeutics, 2010, Volume: 31, Issue:8

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; Treatment Outcome

2010
Efficacy and safety of ticagrelor: a reversible P2Y12 receptor antagonist.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Animals; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine

2010
Clopidogrel non-responsiveness and risk of cardiovascular morbidity. An updated meta-analysis.
    Thrombosis and haemostasis, 2010, Volume: 103, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Evidence-Based Medicine; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Publication Bias; Recurrence; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2010
Clinical implications of clopidogrel non-response in cardiovascular patients: a systematic review and meta-analysis.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2010
Poor response to clopidogrel: current and future options for its management.
    Journal of thrombosis and thrombolysis, 2010, Volume: 30, Issue:3

    Topics: Cardiovascular Diseases; Clopidogrel; Disease Management; Forecasting; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Failure

2010
Antiplatelet and antithrombotic treatment of patients with peripheral arterial disease.
    International angiology : a journal of the International Union of Angiology, 2010, Volume: 29, Issue:1

    Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Treatment Outcome

2010
Heterogeneity of efficacy and safety of antiplatelet therapy in cardiovascular and cerebrovascular disease.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2010, Volume: 10, Issue:2

    Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2010
Cytochrome P450 2C19*2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysis.
    The pharmacogenomics journal, 2011, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genetic Association Studies; Genotype; Humans; Middle Aged; Polymorphism, Genetic; Recurrence; Risk Factors; Thrombosis; Ticlopidine; United States

2011
Aspirin and clopidogrel resistance: methodological challenges and opportunities.
    Vascular health and risk management, 2010, Mar-24, Volume: 6

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2010
Point-of-care testing for assessment of adequacy of oral antiplatelet therapy in patients with cardiovascular disease.
    Future cardiology, 2010, Volume: 6, Issue:3

    Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Point-of-Care Systems; Ticlopidine

2010
A review of the use of common antiplatelet agents in orthopaedic practice.
    The Journal of bone and joint surgery. British volume, 2010, Volume: 92, Issue:9

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Orthopedics; Perioperative Care; Platelet Aggregation Inhibitors; Preoperative Care; Stents; Thrombosis; Ticlopidine

2010
Prognostic significance of high on-clopidogrel platelet reactivity after percutaneous coronary intervention: systematic review and meta-analysis.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Intention to Treat Analysis; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Prognosis; Stents; Thrombosis; Ticlopidine

2010
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part V. Combination of clopidogrel and acetylsalicylic acid in the treatment of stable patients with atherothrombotic cardiovascular diseases].
    Kardiologiia, 2010, Volume: 50, Issue:5

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arteriosclerosis; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Circulation; Death, Sudden, Cardiac; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Streptokinase; Stroke; Thrombosis; Ticlopidine; Time Factors

2010
Effect of proton pump inhibitors on clinical outcome in patients treated with clopidogrel: a systematic review and meta-analysis.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:12

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prognosis; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome

2010
Review article: combination of clopidogrel and proton pump inhibitors: implications for clinicians.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Humans; Myocardial Infarction; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Stroke; Ticlopidine; Treatment Outcome

2010
NSAID-induced gastrointestinal and cardiovascular injury.
    Current opinion in gastroenterology, 2010, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 2 Inhibitors; Drug Interactions; Gastrointestinal Diseases; Histamine H2 Antagonists; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Ticlopidine

2010
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis.
    JAMA, 2010, Oct-27, Volume: 304, Issue:16

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation Inhibitors; Risk; Stents; Thrombosis; Ticlopidine; Treatment Outcome

2010
ACCF/ACG/AHA 2010 Expert Consensus Document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID
    Circulation, 2010, Dec-14, Volume: 122, Issue:24

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Factors; Thienopyridines; Thiophenes; Ticlopidine

2010
Outcomes of patients receiving clopidogrel prior to cardiac surgery.
    International journal of cardiology, 2012, Apr-05, Volume: 156, Issue:1

    Topics: Cardiac Surgical Procedures; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Preoperative Care; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome

2012
[Efficacy and safety of various doses of acetylsalicylic Acid in prevention of complications of atherothrombosis].
    Kardiologiia, 2010, Volume: 50, Issue:10

    Topics: Aspirin; Blood Platelets; Blood Vessels; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Drug Dosage Calculations; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Assessment; Secondary Prevention; Stomach Ulcer; Thrombosis; Ticlopidine; Treatment Outcome

2010
ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID
    The American journal of gastroenterology, 2010, Volume: 105, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Factors; Thienopyridines; Thiophenes; Ticlopidine

2010
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2011
Platelet function and antiplatelet therapy in cardiovascular disease: implications of genetic polymorphisms.
    Current vascular pharmacology, 2011, Jul-01, Volume: 9, Issue:4

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Genetic Variation; Genotype; Haplotypes; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Ticlopidine

2011
Antiplatelet agents in cardiovascular disease.
    Journal of thrombosis and thrombolysis, 2011, Volume: 31, Issue:3

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Time Factors; United States

2011
[Strategy to manage low dose aspirin-induced gastrointestinal injury].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:2

    Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Famotidine; Gastric Mucosa; Humans; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Proton Pump Inhibitors; Ticlopidine

2011
Clopidogrel and proton pump inhibitors: influence of pharmacological interactions on clinical outcomes and mechanistic explanations.
    JACC. Cardiovascular interventions, 2011, Volume: 4, Issue:4

    Topics: Animals; Biotransformation; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Evidence-Based Medicine; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Practice Guidelines as Topic; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine

2011
Recent developments in the use of antiplatelet agents to prevent cardiovascular events.
    Future cardiology, 2011, Volume: 7, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Genetic Predisposition to Disease; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2011
Clopidogrel with proton pump inhibitors: safe or not?
    Clinical cardiology, 2011, Volume: 34, Issue:9

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Ticlopidine

2011
[Interaction between clopidogrel and proton pump inhibitors].
    Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155, Issue:28

    Topics: Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2011
Clopidogrel resistance: identifying and overcoming a barrier to effective antiplatelet treatment.
    Cardiovascular therapeutics, 2011, Volume: 29, Issue:6

    Topics: Animals; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2Y Receptor Antagonists; Ticlopidine; Treatment Failure

2011
The interaction between proton pump inhibitors and clopidogrel and upper gastrointestinal bleeding.
    Gastrointestinal endoscopy clinics of North America, 2011, Volume: 21, Issue:4

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Upper Gastrointestinal Tract

2011
Latest clinical data on testing for high on-treatment platelet reactivity.
    Reviews in cardiovascular medicine, 2011, Volume: 12 Suppl 1

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Monitoring; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2011
P2Y12 platelet inhibition in clinical practice.
    Journal of thrombosis and thrombolysis, 2012, Volume: 33, Issue:2

    Topics: Adenosine; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Ticlopidine

2012
Lack of significant interactions between clopidogrel and proton pump inhibitor therapy: meta-analysis of existing literature.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Death; Drug Interactions; Drug Therapy, Combination; Humans; Outcome and Process Assessment, Health Care; Patient Readmission; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Adjustment; Risk Assessment; Ticlopidine

2012
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis.
    JAMA, 2011, Dec-28, Volume: 306, Issue:24

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Randomized Controlled Trials as Topic; Risk; Thrombosis; Ticlopidine

2011
Quantitative comparison of clopidogrel 600 mg, prasugrel and ticagrelor, against clopidogrel 300 mg on major adverse cardiovascular events and bleeding in coronary stenting: synthesis of CURRENT-OASIS-7, TRITON-TIMI-38 and PLATO.
    International journal of cardiology, 2012, Jul-12, Volume: 158, Issue:2

    Topics: Adenosine; Animals; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Piperazines; Prasugrel Hydrochloride; Thiophenes; Ticagrelor; Ticlopidine

2012
Effects of combined aspirin and clopidogrel therapy on cardiovascular outcomes: a systematic review and meta-analysis.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome

2012
Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation.
    Pharmacogenomics, 2012, Volume: 13, Issue:4

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Biomarkers, Pharmacological; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Genotype; Humans; Polymorphism, Genetic; Ticlopidine; Warfarin

2012
Optimal drug therapy after aspirin-induced upper gastrointestinal bleeding.
    European journal of internal medicine, 2012, Volume: 23, Issue:3

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine

2012
Genetic and non-genetic factors affecting the response to clopidogrel therapy.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2012
No consistent evidence of differential cardiovascular risk amongst proton-pump inhibitors when used with clopidogrel: meta-analysis.
    International journal of cardiology, 2013, Aug-10, Volume: 167, Issue:3

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Humans; Observational Studies as Topic; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Registries; Risk Factors; Ticlopidine

2013
Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:7

    Topics: Aryldialkylphosphatase; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine

2012
Comparative pharmacokinetics and pharmacodynamics of platelet adenosine diphosphate receptor antagonists and their clinical implications.
    Clinical pharmacokinetics, 2012, Jul-01, Volume: 51, Issue:7

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine

2012
Clopidogrel and proton pump inhibitors--where do we stand in 2012?
    World journal of gastroenterology, 2012, May-14, Volume: 18, Issue:18

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine

2012
Network meta-analysis of prasugrel, ticagrelor, high- and standard-dose clopidogrel in patients scheduled for percutaneous coronary interventions.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine; Angioplasty; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Odds Ratio; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Risk; Stents; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2012
Personalized medicine: hope or hype?
    European heart journal, 2012, Volume: 33, Issue:13

    Topics: Anticoagulants; Cardiovascular Diseases; Clopidogrel; Genetic Predisposition to Disease; Genetic Testing; Genetic Variation; Genome, Human; Humans; Mutation; Neoplasms; Pharmacogenetics; Platelet Aggregation Inhibitors; Precision Medicine; Risk Adjustment; Ticlopidine; Warfarin

2012
Interindividual variability in the efficacy of oral antiplatelet drugs: definitions, mechanisms and clinical importance.
    Current pharmaceutical design, 2012, Volume: 18, Issue:33

    Topics: Administration, Oral; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Comorbidity; Drug Interactions; Drug Resistance; Genotype; Humans; Medication Adherence; Patient Selection; Phenotype; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticlopidine; Treatment Outcome

2012
Clinical use of clopidogrel.
    Current pharmaceutical design, 2012, Volume: 18, Issue:33

    Topics: Blood Platelets; Calcium Channel Blockers; Cardiovascular Diseases; Clopidogrel; Drug Design; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Patient Selection; Platelet Aggregation Inhibitors; Platelet Function Tests; Practice Guidelines as Topic; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Ticlopidine; Treatment Outcome

2012
Cilostazol added to aspirin and clopidogrel reduces revascularization without increases in major adverse events in patients with drug-eluting stents: a meta-analysis of randomized controlled trials.
    International journal of cardiology, 2013, Sep-01, Volume: 167, Issue:5

    Topics: Aspirin; Cardiovascular Diseases; Cilostazol; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Tetrazoles; Ticlopidine

2013
Concomitant use of clopidogrel and proton pump inhibitors: impact on platelet function and clinical outcome- a systematic review.
    Heart (British Cardiac Society), 2013, Volume: 99, Issue:8

    Topics: Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Odds Ratio; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2013
Advances in the monitoring of anti-P2Y12 therapy.
    Platelets, 2012, Volume: 23, Issue:7

    Topics: Adenosine; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Precision Medicine; Prodrugs; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Ticlopidine

2012
Primary prevention of ischaemic cardiovascular disorders with antiplatelet agents.
    Handbook of experimental pharmacology, 2012, Issue:210

    Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Ischemia; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Thrombosis; Ticlopidine

2012
Clinical importance of antiplatelet drugs in cardiovascular diseases.
    Clinical hemorheology and microcirculation, 2013, Volume: 53, Issue:1-2

    Topics: Acute Coronary Syndrome; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase Inhibitors; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine

2013
New anti-platelet agents: the end of resistance?
    Thrombosis research, 2012, Volume: 130 Suppl 1

    Topics: Adenosine; Animals; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Design; Drug Resistance; Drug Therapy, Combination; Evidence-Based Medicine; Hemorrhage; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine

2012
Dual antiplatelet therapy for primary and secondary prevention.
    Minerva cardioangiologica, 2012, Volume: 60, Issue:6

    Topics: Acute Coronary Syndrome; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Secondary Prevention; Ticlopidine

2012
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Ticlopidine

2012
Branded versus generic clopidogrel in cardiovascular diseases: a systematic review.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:4

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drugs, Generic; Humans; Patents as Topic; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome; United States

2013
Dual antiplatelet therapy with prasugrel or ticagrelor versus clopidogrel in interventional cardiology.
    Cardiovascular drugs and therapy, 2013, Volume: 27, Issue:3

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Humans; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Stents; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2013
Clopidogrel: potential in the prevention of cardiovascular events in patients with acute coronary syndromes.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2001, Volume: 1, Issue:6

    Topics: Angioplasty, Balloon; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2001
[Interactions of statins with antithrombotic drugs].
    Medizinische Klinik (Munich, Germany : 1983), 2004, Feb-15, Volume: 99, Issue:2

    Topics: Animals; Anticholesteremic Agents; Aspirin; Atorvastatin; Cardiovascular Diseases; Clopidogrel; Controlled Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Follow-Up Studies; Hemostasis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Pravastatin; Primary Prevention; Pyrroles; Rats; Ticlopidine; Time Factors

2004
Peripheral arterial disease. A systemic disease extending beyond the affected extremity.
    Geriatrics, 2004, Volume: 59, Issue:4

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Exercise; Geriatrics; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Smoking Cessation; Ticlopidine

2004
Hypothesis: atorvastatin has pleiotropic effects that translate into early clinical benefits on cardiovascular disease.
    Journal of cardiovascular pharmacology and therapeutics, 2004, Volume: 9, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Heptanoic Acids; Humans; Lipid Peroxidation; Platelet Aggregation Inhibitors; Pyrroles; Randomized Controlled Trials as Topic; Ticlopidine

2004
CD40 ligand: a novel target in the fight against cardiovascular disease.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:9

    Topics: Cardiovascular Agents; Cardiovascular Diseases; CD40 Ligand; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thiazolidinediones; Ticlopidine

2004
Platelet function testing in cardiovascular diseases.
    Circulation, 2004, Nov-09, Volume: 110, Issue:19

    Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Case Management; Clopidogrel; Drug Resistance; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine; Treatment Outcome

2004
[Cardiovascular risk in diabetes--diagnostic and therapeutic aspects].
    MMW Fortschritte der Medizin, 2004, Sep-02, Volume: 146, Issue:35-36

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal; Aspirin; Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypolipidemic Agents; Immunoglobulin Fab Fragments; Insulin; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Primary Prevention; Risk; Risk Factors; Stents; Ticlopidine; Time Factors

2004
Prevention of cardiovascular events in diabetes.
    Clinical evidence, 2003, Issue:10

    Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Diabetic Angiopathies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation; Ticlopidine

2003
[Aspirin: recent advances in cardiovascular prevention].
    Revue medicale de Liege, 2004, Volume: 59, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Ticlopidine

2004
Combination antiplatelet agents in ischemic cerebrovascular disease.
    The Mount Sinai journal of medicine, New York, 2005, Volume: 72, Issue:1

    Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2005
Aspirin and clopidogrel: a sweeping combination in cardiology.
    Current medicinal chemistry. Cardiovascular and hematological agents, 2005, Volume: 3, Issue:3

    Topics: Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Humans; Ticlopidine

2005
Female-specific aspects in the pharmacotherapy of chronic cardiovascular diseases.
    European heart journal, 2005, Volume: 26, Issue:16

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Digitalis Glycosides; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Sex Factors; Ticlopidine; Women's Health

2005
Balancing the benefit and risk of oral antiplatelet agents in coronary artery bypass surgery.
    The Annals of thoracic surgery, 2005, Volume: 80, Issue:2

    Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Graft Occlusion, Vascular; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Assessment; Ticlopidine

2005
[Place of ticlopidine in antiplatelet treatment].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2005, Volume: 19, Issue:110

    Topics: Animals; Cardiovascular Diseases; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2005
Aspirin and clopidogrel resistance: an emerging clinical entity.
    European heart journal, 2006, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2006
Combination of clopidogrel and statins: a hypothetical interaction or therapeutic dilemma?
    Pharmacotherapy, 2006, Volume: 26, Issue:3

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Ticlopidine

2006
[Cardiological (pharmaco)therapy and dental practice].
    Nederlands tijdschrift voor tandheelkunde, 2006, Volume: 113, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Thrombosis; Defibrillators, Implantable; Heart Valve Prosthesis; Humans; Oral Surgical Procedures; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Ticlopidine

2006
Aspirin and clopidogrel resistance.
    Mayo Clinic proceedings, 2006, Volume: 81, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance, Multiple; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2006
Aspirin resistance: does it exist and is it an important clinical problem?
    Clinical advances in hematology & oncology : H&O, 2006, Volume: 4, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Resistance; Humans; Myeloproliferative Disorders; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine

2006
Prevention of cardiovascular events in diabetes.
    Clinical evidence, 2006, Issue:15

    Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Clopidogrel; Diabetic Angiopathies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation; Ticlopidine

2006
Does a coxib-associated thrombotic risk limit the clinical use of the compounds as analgesic, antiinflammatory drugs? Arguments against.
    Thrombosis and haemostasis, 2006, Volume: 96, Issue:4

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 2 Inhibitors; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Patient Selection; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Thrombosis; Ticlopidine

2006
Possible mechanisms of drug-induced aspirin and clopidogrel resistance.
    Journal of thrombosis and thrombolysis, 2006, Volume: 22, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Resistance; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Ticlopidine

2006
[Tiklopidin--30 years of clinical application].
    Terapevticheskii arkhiv, 2006, Volume: 78, Issue:8

    Topics: Cardiovascular Diseases; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2006
[Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:9 Spec No

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cyclooxygenase Inhibitors; Drug Interactions; Follow-Up Studies; Humans; Ibuprofen; MEDLINE; Middle Aged; Multivariate Analysis; Naproxen; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Thromboxane B2; Ticlopidine; Time Factors

2006
Clopidogrel resistance?
    Thrombosis research, 2007, Volume: 120, Issue:3

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Membrane Proteins; Models, Biological; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine

2007
Impact of chronic kidney disease and diabetes on percutaneous coronary intervention outcomes.
    Reviews in cardiovascular medicine, 2006, Volume: 7 Suppl 4

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Drug-Eluting Stents; Glucose; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2006
Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI).
    Vascular health and risk management, 2006, Volume: 2, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Drug Resistance; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; Treatment Outcome

2006
Thienopyridines in cardiovascular disease: focus on clopidogrel resistance.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:3

    Topics: Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Design; Drug Resistance; Drugs, Investigational; Humans; Membrane Proteins; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2007
[The best of interventional cardiology in 2006].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100 Spec No 1

    Topics: Angioplasty, Balloon, Coronary; Cardiology; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Coronary Restenosis; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2007
Antiplatelet therapy in the treatment of atherothrombotic disease: considering the evidence.
    Geriatrics, 2007, Volume: 62, Issue:4

    Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Comorbidity; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Male; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine

2007
Variable platelet response to aspirin and clopidogrel in atherothrombotic disease.
    Circulation, 2007, Apr-24, Volume: 115, Issue:16

    Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Biomarkers; Biotransformation; Blood Coagulation Tests; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resistance; Hemorrhage; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Thromboxane A2; Thromboxane B2; Ticlopidine; Treatment Failure

2007
The cost of new therapies in cardiovascular care. Time for hope or despair for developing countries.
    Saudi medical journal, 2007, Volume: 28, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Developing Countries; Heart Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2007
Clinical aspects of platelet inhibitors and thrombus formation.
    Circulation research, 2007, May-11, Volume: 100, Issue:9

    Topics: Aspirin; Atherosclerosis; Blood Platelets; Cardiovascular Diseases; Cilostazol; Clopidogrel; Dipyridamole; Drug Resistance; Humans; Pentanoic Acids; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, PAR-1; Stents; Tetrazoles; Thrombosis; Thromboxanes; Ticlopidine

2007
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2007
Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis.
    American heart journal, 2007, Volume: 154, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Prevalence; Stents; Ticlopidine

2007
Incremental effect of clopidogrel on important outcomes in patients with cardiovascular disease: a meta-analysis of randomized trials.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Stroke; Ticlopidine

2007
Upper GI risks of NSAIDs and antiplatelet agents: key issues for the cardiologist.
    Reviews in cardiovascular medicine, 2005, Volume: 6 Suppl 4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Health Care Costs; Helicobacter Infections; Helicobacter pylori; Humans; Patient Selection; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stomach Ulcer; Ticlopidine

2005
Clopidogrel: who, when, and how?
    Reviews in cardiovascular medicine, 2007, Volume: 8 Suppl 3

    Topics: Acute Disease; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Ischemia; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Secondary Prevention; Syndrome; Ticlopidine; Treatment Outcome

2007
Clopidogrel and risk for acute coronary events.
    Current atherosclerosis reports, 2007, Volume: 9, Issue:5

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2007
Antiplatelet therapy with clopidogrel and aspirin in vascular diseases: clinical evidence for and against the combination.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:3

    Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine

2008
[Platelet response to aspirin and clopidogrel. Biochemical evaluation, clinical impact, and pharmacological modulation].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Flow Cytometry; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine

2007
[Frequently asked questions on clopidogrel treatment: indications, resistance, and biological evaluation in vascular patients].
    Revue medicale suisse, 2008, Feb-06, Volume: 4, Issue:143

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2008
[Ticlopidine].
    Terapevticheskii arkhiv, 1994, Volume: 66, Issue:10

    Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Platelet Aggregation; Ticlopidine

1994
Clinical pharmacokinetics of ticlopidine.
    Clinical pharmacokinetics, 1994, Volume: 26, Issue:5

    Topics: Adult; Aged; Aging; Animals; Bleeding Time; Blood Platelets; Cardiovascular Diseases; Drug Interactions; Humans; Rats; Ticlopidine

1994
Ticlopidine and antiplatelet therapy.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:9

    Topics: Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Interactions; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Ticlopidine

1993
Antiplatelet therapy in the treatment of cerebrovascular disease.
    Clinical cardiology, 1993, Volume: 16, Issue:10

    Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine

1993
The antiplatelet effects of ticlopidine and clopidogrel.
    Annals of internal medicine, 1998, Sep-01, Volume: 129, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Costs; Female; Humans; Male; Neutropenia; Platelet Aggregation Inhibitors; Ticlopidine

1998
Antiplatelet drugs.
    The Medical journal of Australia, 1999, Apr-19, Volume: 170, Issue:8

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Cardiovascular Diseases; Dipyridamole; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Ticlopidine

1999
Therapeutic benefit. Aspirin revisited in light of the introduction of clopidogrel.
    Stroke, 1999, Volume: 30, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Decision Making; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Treatment Outcome

1999
Antiplatelet agents in the prevention of cardiovascular morbidity and mortality in older patients with vascular disease.
    Drugs & aging, 1999, Volume: 15, Issue:2

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Diseases

1999
Ticlopidine and clopidogrel.
    Circulation, 1999, Oct-12, Volume: 100, Issue:15

    Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angina, Unstable; Aspirin; Bone Marrow Diseases; Carbamazepine; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug Interactions; Hemorrhage; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Phenytoin; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Safety; Stents; Theophylline; Thrombolytic Therapy; Ticlopidine

1999
Clopidogrel and [symbol: see text] ticlopidine--improvements on aspirin?
    Drug and therapeutics bulletin, 1999, Volume: 37, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Contraindications; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine

1999
Aspirin, ticlopidine and clopidogrel in and out of the catheterization laboratory.
    The Journal of invasive cardiology, 1999, Volume: 11 Suppl A

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

1999
Thienopyridine derivatives (ticlopidine, clopidogrel) versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2000
[Platelet antiaggregants].
    Medicina clinica, 2000, Jul-08, Volume: 115, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Dipyridamole; Drug Utilization; Fibrinolytic Agents; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Risk Factors; Spain; Ticlopidine

2000
Novel platelet inhibitors.
    Annual review of medicine, 2001, Volume: 52

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome

2001
The role of adenosine 5'-diphosphate receptor blockade in patients with cardiovascular disease.
    The American journal of medicine, 2001, Volume: 111, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Ticlopidine

2001
Role of antiplatelet agents in cardioprotection.
    The American journal of managed care, 2002, Volume: 8, Issue:9 Suppl

    Topics: Arteriosclerosis; Aspirin; Cardiotonic Agents; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; United States

2002
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Female; Glomerulonephritis; Graft Occlusion, Vascular; Heart Valve Prosthesis; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Postoperative Complications; Random Allocation; Sulfinpyrazone; Thiophenes; Ticlopidine

1986

Trials

67 trial(s) available for ticlopidine and Cardiovascular Diseases

ArticleYear
Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Patients Treated With P2Y12 Inhibitors.
    Journal of the American Heart Association, 2023, 10-17, Volume: 12, Issue:20

    Topics: Acute Coronary Syndrome; Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Secondary Prevention; Ticlopidine

2023
Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome: The TICO Randomized Clinical Trial.
    JAMA, 2020, 06-16, Volume: 323, Issue:23

    Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Sirolimus; Ticlopidine

2020
Use of the Dual-Antiplatelet Therapy Score to Guide Treatment Duration After Percutaneous Coronary Intervention.
    Annals of internal medicine, 2017, Jul-04, Volume: 167, Issue:1

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome

2017
Antithrombotic potency of ticagrelor versus clopidogrel in type-2 diabetic patients with cardiovascular disease.
    Thrombosis and haemostasis, 2017, 10-05, Volume: 117, Issue:10

    Topics: Adenosine; Aged; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Thrombosis; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome

2017
Clopidogrel Therapy in Patients with Cardiovascular Disease Undergoing Transurethral Resection of the Prostate: A Step Towards Individualization.
    Drugs & aging, 2017, Volume: 34, Issue:12

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Humans; Male; P-Selectin; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Prostatic Hyperplasia; Ticlopidine; Transurethral Resection of Prostate

2017
Development, validation and application of a novel HPLC-MS/MS method for the quantification of atorvastatin, bisoprolol and clopidogrel in a large cardiovascular patient cohort.
    Journal of pharmaceutical and biomedical analysis, 2018, Sep-10, Volume: 159

    Topics: Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Bisoprolol; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Clopidogrel; Cohort Studies; Female; Humans; Male; Mass Spectrometry; Platelet Aggregation Inhibitors; Prospective Studies; Reproducibility of Results; Tandem Mass Spectrometry; Ticlopidine

2018
Relationship of CYP2C19*2 and CYP2C19*3 gene polymorphism with clopidogrel response variability and recurrent cardiovascular events in Chinese patients undergoing percutaneous coronary intervention.
    Pharmacology, 2013, Volume: 91, Issue:3-4

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Asian People; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2Y Receptor Antagonists; Ticlopidine; Treatment Outcome

2013
Quantitative ST-depression in acute coronary syndromes: the PLATO electrocardiographic substudy.
    The American journal of medicine, 2013, Volume: 126, Issue:8

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Electrocardiography; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Prognosis; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome

2013
Clinical pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases.
    Clinical pharmacokinetics, 2014, Volume: 53, Issue:2

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2014
Relationship between statin type and responsiveness to clopidogrel in patients treated with percutaneous coronary intervention: a subgroup analysis of the CILON-T trial.
    Journal of atherosclerosis and thrombosis, 2014, Volume: 21, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Atorvastatin; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Combined Modality Therapy; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Fluorobenzenes; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prognosis; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Ticlopidine

2014
A randomized controlled trial of platelet activity before and after cessation of clopidogrel therapy in patients with stable cardiovascular disease.
    Journal of the American College of Cardiology, 2014, Jan-28, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Treatment Outcome; Withholding Treatment

2014
The influence of genetic polymorphism of Cyp2c19 isoenzyme on the pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:8

    Topics: Area Under Curve; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Isoenzymes; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2014
Pharmacodynamic effects of cilostazol versus clopidogrel in stented patients under proton pump inhibitor co-administration: the ACCEL-PARAZOL study.
    Journal of atherosclerosis and thrombosis, 2014, Volume: 21, Issue:11

    Topics: Cardiovascular Diseases; Cilostazol; Clopidogrel; Female; Follow-Up Studies; Humans; Lansoprazole; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Prospective Studies; Proton Pump Inhibitors; Renal Insufficiency, Chronic; Stents; Tetrazoles; Ticlopidine

2014
Does rectal indomethacin given for prevention of post-ERCP pancreatitis increase bleeding after biliary endoscopic sphincterotomy or cardiovascular mortality?: Post hoc analysis using prospective clinical trial data.
    Medicine, 2014, Volume: 93, Issue:26

    Topics: Administration, Rectal; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cholangiopancreatography, Endoscopic Retrograde; Clopidogrel; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Pancreatitis; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Sphincterotomy, Endoscopic; Ticlopidine

2014
Association between Antiplatelet or Anticoagulant Drugs and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials.
    Ophthalmology, 2016, Volume: 123, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anticoagulants; Aspirin; Bevacizumab; Cardiovascular Diseases; Clopidogrel; Female; Fluorescein Angiography; Humans; Hypertension; Intravitreal Injections; Male; Odds Ratio; Platelet Aggregation Inhibitors; Ranibizumab; Retinal Hemorrhage; Risk Factors; Ticlopidine; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Warfarin; Wet Macular Degeneration

2016
Salts of Clopidogrel: Investigation to Ensure Clinical Equivalence: A 12-Month Randomized Clinical Trial.
    Journal of cardiovascular pharmacology and therapeutics, 2016, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Drug Compounding; Drugs, Generic; Female; Greece; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Secondary Prevention; Stroke; Therapeutic Equivalency; Ticlopidine; Time Factors; Treatment Outcome

2016
Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
    American heart journal, 2016, Volume: 177

    Topics: Abciximab; Acute Coronary Syndrome; Adenosine; Aged; Antibodies, Monoclonal; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Eptifibatide; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Peptides; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2Y Receptor Antagonists; Stroke; Thrombosis; Ticagrelor; Ticlopidine; Tirofiban; Tyrosine

2016
Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study.
    American heart journal, 2017, Volume: 184

    Topics: Aortic Valve Stenosis; Aspirin; Cardiovascular Diseases; Cause of Death; Clopidogrel; Drug Therapy, Combination; Embolism; Factor Xa Inhibitors; Heart Valve Diseases; Humans; Mortality; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Pulmonary Embolism; Rivaroxaban; Stroke; Thrombosis; Ticlopidine; Transcatheter Aortic Valve Replacement; Venous Thrombosis

2017
Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease.
    The New England journal of medicine, 2017, 01-05, Volume: 376, Issue:1

    Topics: Adenosine; Aged; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Female; Hemorrhage; Humans; Intermittent Claudication; Ischemia; Kaplan-Meier Estimate; Leg; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2017
Prasugrel in the poststroke cohort of the TRITON Trial: the clear and present danger.
    Cerebrovascular diseases (Basel, Switzerland), 2008, Volume: 26, Issue:1

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Hemorrhage; Humans; Ischemic Attack, Transient; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Secondary Prevention; Stents; Stroke; Thiophenes; Ticlopidine; Treatment Outcome

2008
Patients with peripheral arterial disease in the CHARISMA trial.
    European heart journal, 2009, Volume: 30, Issue:2

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine

2009
Comparison of methods to evaluate clopidogrel-mediated platelet inhibition after percutaneous intervention with stent implantation.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:2

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reproducibility of Results; Sensitivity and Specificity; Stents; Ticlopidine

2009
Using a drug facts box to communicate drug benefits and harms: two randomized trials.
    Annals of internal medicine, 2009, Apr-21, Volume: 150, Issue:8

    Topics: Adult; Advertising; Aged; Cardiovascular Diseases; Clopidogrel; Consumer Health Information; Female; Heartburn; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Patient Education as Topic; Platelet Aggregation Inhibitors; Prescription Drugs; Proton Pump Inhibitors; Ticlopidine

2009
Clinical outcomes of patients with diabetic nephropathy randomized to clopidogrel plus aspirin versus aspirin alone (a post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance [CHARISMA] tri
    The American journal of cardiology, 2009, May-15, Volume: 103, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Survival Analysis; Ticlopidine; Treatment Outcome

2009
Glycoprotein IIb/IIIa inhibitors improve outcome after coronary stenting in clopidogrel nonresponders: a prospective, randomized study.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Drug Resistance; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Risk Assessment; Stents; Ticlopidine; Time Factors; Treatment Outcome

2008
[Effects of upstream tirofiban versus downstream tirofiban on platelet aggregation and clinical outcomes in patients with high-risk acute coronary syndromes undergoing percutaneous coronary interventions].
    Zhonghua xin xue guan bing za zhi, 2009, Volume: 37, Issue:1

    Topics: Acute Coronary Syndrome; Adult; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine

2009
Smoking, clopidogrel, and mortality in patients with established cardiovascular disease.
    Circulation, 2009, Dec-08, Volume: 120, Issue:23

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Prospective Studies; Smoking; Ticlopidine

2009
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
    Circulation, 2010, Sep-14, Volume: 122, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Kidney Diseases; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome

2010
Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial.
    Lancet (London, England), 2010, Oct-09, Volume: 376, Issue:9748

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2010
Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.
    The New England journal of medicine, 2010, Sep-02, Volume: 363, Issue:10

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Artery Bypass; Double-Blind Method; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Research Design; Stroke; Ticlopidine

2010
Clopidogrel with or without omeprazole in coronary artery disease.
    The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2010
The EFFect of hIgh-dose ClopIdogrel treatmENT in patients with clopidogrel resistance (the EFFICIENT trial).
    International journal of cardiology, 2012, Jun-14, Volume: 157, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Treatment Outcome

2012
Separate dosing of clopidogrel and omeprazole may improve platelet inhibition on dual antiplatelet therapy.
    International journal of cardiology, 2011, May-19, Volume: 149, Issue:1

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Omeprazole; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine

2011
Cilostazol attenuates on-treatment platelet reactivity in patients with CYP2C19 loss of function alleles receiving dual antiplatelet therapy: a genetic substudy of the CILON-T randomised controlled trial.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:8

    Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Cilostazol; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Drug-Eluting Stents; Epidemiologic Methods; Female; Humans; Korea; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Tetrazoles; Ticlopidine; Treatment Outcome

2011
High-sensitivity C-reactive protein and clopidogrel treatment in patients at high risk of cardiovascular events: a substudy from the CHARISMA trial.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:8

    Topics: Aged; Aspirin; Atherosclerosis; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2011
Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial.
    JAMA, 2011, Mar-16, Volume: 305, Issue:11

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk; Thrombosis; Ticlopidine

2011
Modifying clopidogrel maintenance doses according to vasodilator-stimulated phosphoprotein phosphorylation index improves clinical outcome in patients with clopidogrel resistance.
    Clinical cardiology, 2011, Volume: 34, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Drug Resistance; Female; Humans; Kaplan-Meier Estimate; Male; Microfilament Proteins; Phosphoproteins; Platelet Aggregation Inhibitors; Statistics as Topic; Ticlopidine; Treatment Outcome; Vasodilation

2011
Association of cytochrome P450 2C19*2 polymorphism with clopidogrel response variability and cardiovascular events in Koreans treated with drug-eluting stents.
    Heart (British Cardiac Society), 2012, Volume: 98, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Registries; Republic of Korea; Ticlopidine; Treatment Outcome

2012
Combined clopidogrel and proton pump inhibitor therapy is associated with higher cardiovascular event rates after percutaneous coronary intervention: a report from the BASKET trial.
    Journal of internal medicine, 2012, Volume: 271, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine

2012
Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:4

    Topics: Adult; Aged; Aryldialkylphosphatase; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Genetic Association Studies; Genetic Variation; Humans; Male; Middle Aged; Survival Rate; Ticlopidine; Treatment Outcome

2011
Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease.
    JAMA, 2011, Nov-23, Volume: 306, Issue:20

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Double-Blind Method; Female; Genotype; Heterozygote; Homozygote; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome

2011
Combination therapy with warfarin plus clopidogrel improves outcomes in femoropopliteal bypass surgery patients.
    Journal of vascular surgery, 2012, Volume: 56, Issue:1

    Topics: Administration, Oral; Aged; Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Comorbidity; Drug Therapy, Combination; Female; Femoral Artery; Graft Occlusion, Vascular; Humans; Logistic Models; Male; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Popliteal Artery; Proportional Hazards Models; Prospective Studies; Ticlopidine; Treatment Outcome; Vascular Patency; Warfarin

2012
Perioperative assessment of platelet function by Thromboelastograph Platelet Mapping in cardiovascular patients undergoing non-cardiac surgery.
    Journal of thrombosis and thrombolysis, 2013, Volume: 35, Issue:1

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombelastography; Ticlopidine

2013
Dual antiplatelet therapy in patients with aspirin resistance following coronary artery bypass grafting: study protocol for a randomized controlled trial [NCT01159639].
    Trials, 2012, Aug-25, Volume: 13

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Croatia; Drug Resistance; Drug Therapy, Combination; Hemorrhage; Humans; Patient Readmission; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Ticlopidine; Time Factors; Treatment Outcome

2012
Prasugrel versus clopidogrel for acute coronary syndromes without revascularization.
    The New England journal of medicine, 2012, Oct-04, Volume: 367, Issue:14

    Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Stroke; Thiophenes; Ticlopidine

2012
Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: a substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial.
    Circulation. Cardiovascular quality and outcomes, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Acute Coronary Syndrome; Adenosine; Age Factors; Aged; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Double-Blind Method; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Patient Safety; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Stents; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome

2012
Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet f
    Journal of the American College of Cardiology, 2013, Feb-26, Volume: 61, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Coagulation; Cardiovascular Diseases; Clopidogrel; Confounding Factors, Epidemiologic; Cross-Over Studies; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Proton Pump Inhibitors; Smoking; Ticlopidine

2013
Long term prognosis in patients with peripheral arterial disease treated with antiplatelet agents.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2003, Volume: 26, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cause of Death; Female; Follow-Up Studies; Humans; Intermittent Claudication; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Ticlopidine

2003
Clopidogrel: potential in the prevention of cardiovascular events in patients with acute coronary syndromes.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2001, Volume: 1, Issue:6

    Topics: Angioplasty, Balloon; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2001
Clopidogrel added to aspirin versus aspirin alone in secondary prevention and high-risk primary prevention: rationale and design of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial.
    American heart journal, 2004, Volume: 148, Issue:2

    Topics: Arteriosclerosis; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Thrombosis; Ticlopidine

2004
Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding.
    The New England journal of medicine, 2005, Jan-20, Volume: 352, Issue:3

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine

2005
Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial.
    Circulation, 2005, Jun-28, Volume: 111, Issue:25

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemorrhage; Humans; Incidence; Male; Membrane Proteins; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2005
A global view of atherothrombosis: baseline characteristics in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial.
    American heart journal, 2005, Volume: 150, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Coronary Disease; Female; Humans; Ischemia; Leg; Male; Middle Aged; Myocardial Infarction; Risk Factors; Ticlopidine

2005
Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events.
    The New England journal of medicine, 2006, Apr-20, Volume: 354, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Thrombosis; Ticlopidine

2006
Cardiac events after low osmolar ionic or isosmolar nonionic contrast media utilization in the current era of coronary angioplasty.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 67, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Contrast Media; Coronary Angiography; Drug Delivery Systems; Enoxaparin; Female; Humans; Incidence; Ioxaglic Acid; Male; Middle Aged; Osmolar Concentration; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Risk Factors; Stents; Thrombosis; Ticlopidine; Triiodobenzoic Acids

2006
Overcoming aspirin resistance: increased platelet inhibition with combination aspirin and clopidogrel and high dose aspirin therapy in aspirin resistant patients with peripheral vascular disease.
    Thrombosis and haemostasis, 2006, Volume: 95, Issue:6

    Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2006
Response to aspirin and clopidogrel in patients scheduled to undergo cardiovascular surgery.
    Journal of thrombosis and thrombolysis, 2007, Volume: 24, Issue:1

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Preoperative Care; Ticlopidine; Treatment Outcome

2007
Oral anticoagulant and antiplatelet therapy and peripheral arterial disease.
    The New England journal of medicine, 2007, Jul-19, Volume: 357, Issue:3

    Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin

2007
Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial.
    Journal of the American College of Cardiology, 2007, Jul-24, Volume: 50, Issue:4

    Topics: Atorvastatin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Pravastatin; Prospective Studies; Pyrroles; Ticlopidine

2007
An analysis of mortality rates with dual-antiplatelet therapy in the primary prevention population of the CHARISMA trial.
    European heart journal, 2007, Volume: 28, Issue:18

    Topics: Aged; Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Disease-Free Survival; Drug Therapy, Combination; Epidemiologic Methods; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2007
Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:1

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Atorvastatin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Coronary Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Female; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrroles; Simvastatin; Stents; Ticlopidine; Time Factors; Treatment Outcome

2008
Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study.
    Journal of the American College of Cardiology, 2008, Apr-08, Volume: 51, Issue:14

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Female; Humans; Male; Microfilament Proteins; Myocardial Infarction; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Vasodilation

2008
Major benefit from antiplatelet therapy for patients at high risk for adverse cardiac events after coronary Palmaz-Schatz stent placement: analysis of a prospective risk stratification protocol in the Intracoronary Stenting and Antithrombotic Regimen (ISA
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Diseases; Combined Modality Therapy; Coronary Disease; Death, Sudden, Cardiac; Fibrinolytic Agents; Heparin; Humans; Incidence; Myocardial Infarction; Phenprocoumon; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Recurrence; Reoperation; Risk Factors; Stents; Ticlopidine

1997
Ticlopidine pretreatment before coronary stenting is associated with sustained decrease in adverse cardiac events: data from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting (EPISTENT) Trial.
    Circulation, 2001, Mar-13, Volume: 103, Issue:10

    Topics: Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Models, Statistical; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine

2001
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.
    The New England journal of medicine, 2001, Aug-16, Volume: 345, Issue:7

    Topics: Acute Disease; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2001
Is it possible to reduce the risk of cardiovascular events in subjects suffering from intermittent claudication of the lower limbs?
    Thrombosis and haemostasis, 1989, Sep-29, Volume: 62, Issue:2

    Topics: Cardiovascular Diseases; Double-Blind Method; Female; Follow-Up Studies; Humans; Intermittent Claudication; Leg; Male; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine

1989
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Female; Glomerulonephritis; Graft Occlusion, Vascular; Heart Valve Prosthesis; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Postoperative Complications; Random Allocation; Sulfinpyrazone; Thiophenes; Ticlopidine

1986

Other Studies

278 other study(ies) available for ticlopidine and Cardiovascular Diseases

ArticleYear
Utility of a pharmacogenetic-driven algorithm in guiding dual antiplatelet therapy for patients undergoing coronary drug-eluting stent implantation in China.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:2

    Topics: Aged; Algorithms; Asian People; Aspirin; Cardiovascular Diseases; China; Clopidogrel; Comorbidity; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Health Behavior; Hemorrhage; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Assessment; Risk Factors; Sociodemographic Factors; Ticagrelor; Ticlopidine

2022
COX-1, COX-2 and CYP2C19 variations may be related to cardiovascular events due to acetylsalicylic acid resistance.
    Molecular biology reports, 2022, Volume: 49, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase 2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Resistance; Genotype; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2022
[Evaluation of PFA P2Y assay in monitoring platelet function in elderly patients with cardiovascular disease receiving clopidogrel treatment].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016, Apr-20, Volume: 37, Issue:4

    Topics: Biological Assay; Blood Coagulation Tests; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Ticlopidine

2016
Gender-related differences in antiplatelet treatment patterns and outcome: Insights from the GReekAntiPlatElet Registry.
    Cardiovascular therapeutics, 2017, Volume: 35, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Female; Greece; Hemorrhage; Humans; Ischemia; Male; Middle Aged; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Registries; Risk Factors; Sex Characteristics; Stents; Ticlopidine; Treatment Outcome

2017
Dyspnea Attributed to Ticagrelor: Variable Tolerability in Different Clinical Settings.
    The Canadian journal of cardiology, 2017, Volume: 33, Issue:6

    Topics: Aged; Cardiovascular Diseases; Drug Tolerance; Dyspnea; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2017
Quantification of bleeding during dental extraction in patients on dual antiplatelet therapy.
    International journal of oral and maxillofacial surgery, 2017, Volume: 46, Issue:9

    Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Dental Care for Chronically Ill; Female; Hemorrhage; Hemostasis, Surgical; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Tooth Extraction

2017
Clinical determinants of clopidogrel responsiveness in a heterogeneous cohort of Puerto Rican Hispanics.
    Therapeutic advances in cardiovascular disease, 2017, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Blood Platelets; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Cross-Sectional Studies; Drug Resistance; Female; Hispanic or Latino; Humans; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Puerto Rico; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2017
Association of CYP2C19*2 polymorphism with clopidogrel response and 1-year major adverse cardiovascular events in a multiethnic population with drug-eluting stents.
    Pharmacogenomics, 2017, Volume: 18, Issue:13

    Topics: Alleles; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Drug-Related Side Effects and Adverse Reactions; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Risk Factors; Ticlopidine

2017
Poor prognosis after surgery for intertrochanteric fracture in elderly patients with clopidogrel treatment: A cohort study.
    Medicine, 2017, Volume: 96, Issue:39

    Topics: Aged; Blood Loss, Surgical; Blood Transfusion; Cardiovascular Diseases; China; Clopidogrel; Cohort Studies; Female; Fracture Fixation, Intramedullary; Hip Fractures; Humans; Intraoperative Complications; Length of Stay; Male; Operative Time; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Ticlopidine; Treatment Outcome

2017
Clinical characteristics and outcomes of patients with coronary artery spasm who initially presented with acute myocardial infarction.
    Coronary artery disease, 2018, Volume: 29, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Coronary Vasospasm; Female; Follow-Up Studies; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Propensity Score; Proportional Hazards Models; Recurrence; Retrospective Studies; Ticlopidine

2018
To Have and Have Not: Intrinsic Platelet Hyperreactivity?
    Journal of the American Heart Association, 2018, 03-03, Volume: 7, Issue:5

    Topics: Adenosine Diphosphate; Blood Platelets; Cardiovascular Diseases; Humans; Longitudinal Studies; Ticlopidine

2018
Review: Adding clopidogrel to ASA reduces CV morbidity but increases bleeding in patients at high risk for CV events.
    Annals of internal medicine, 2018, 04-17, Volume: 168, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2018
Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome.
    Heart (British Cardiac Society), 2019, Volume: 105, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Assessment; Scotland; Stroke; Ticlopidine; Time Factors; Withholding Treatment

2019
Aspirin Plus Clopidogrel vs Aspirin Alone for Preventing Cardiovascular Events Among Patients at High Risk for Cardiovascular Events.
    JAMA, 2018, 08-14, Volume: 320, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Review Literature as Topic; Stroke; Ticlopidine

2018
The impact of CYP2C19 genotype on cardiovascular events and platelet reactivity in patients with coronary artery disease receiving clopidogrel.
    International journal of cardiology, 2013, Sep-30, Volume: 168, Issue:2

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2013
[Is antiplatelet therapy always effective?].
    Vnitrni lekarstvi, 2012, Volume: 58, Issue:12

    Topics: Adult; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome

2012
Comparative effect of clopidogrel plus aspirin and aspirin monotherapy on hematological parameters using propensity score matching.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Humans; Leukocyte Count; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Propensity Score; Risk Factors; Ticlopidine; Treatment Outcome

2013
A Boolean view separates platelet activatory and inhibitory signalling as verified by phosphorylation monitoring including threshold behaviour and integrin modulation.
    Molecular bioSystems, 2013, Volume: 9, Issue:6

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Iloprost; Integrins; Milrinone; Models, Biological; Molecular Dynamics Simulation; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Ticlopidine

2013
[Your patient needs antithrombotics, 2. What do the new substances offer? (interview by Dr. med. Peter Stiefelhagen)].
    MMW Fortschritte der Medizin, 2013, Feb-21, Volume: 155, Issue:3

    Topics: Adenosine; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cardiovascular Diseases; Clopidogrel; Dabigatran; Fibrinolytic Agents; Guideline Adherence; Humans; Morpholines; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyrazoles; Pyridones; Rivaroxaban; Thiophenes; Thromboembolism; Ticagrelor; Ticlopidine; Treatment Outcome

2013
High on-treatment platelet reactivity predicts cardiac events in patients with drug-eluting stents.
    Arquivos brasileiros de cardiologia, 2013, Volume: 100, Issue:3

    Topics: Aged; Brazil; Cardiovascular Diseases; Clopidogrel; Drug-Eluting Stents; Epidemiologic Methods; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reference Standards; Risk Factors; Ticlopidine

2013
Preserved thrombin-inducible platelet activation in thienopyridine-treated patients.
    European journal of clinical investigation, 2013, Volume: 43, Issue:7

    Topics: Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Female; Humans; Integrin beta3; Male; Middle Aged; P-Selectin; Peptide Fragments; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thiophenes; Thrombin; Ticlopidine

2013
Pharmacogenomics in cardiovascular disease: focus on aspirin and ADP receptor antagonists.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:9

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Pharmacogenetics; Purinergic P2Y Receptor Antagonists; Ticlopidine

2013
Comparison of clinical efficacy and safety of clopidogrel resinate with clopidogrel bisulfate in patients undergoing percutaneous coronary intervention.
    Cardiovascular drugs and therapy, 2013, Volume: 27, Issue:5

    Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Treatment Outcome

2013
Long-term effect of dual antiplatelet treatment after off-pump coronary artery bypass grafting.
    Journal of cardiac surgery, 2013, Volume: 28, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Coronary Artery Bypass, Off-Pump; Drug Therapy, Combination; Endpoint Determination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Complications; Prognosis; Retrospective Studies; Ticlopidine; Time Factors

2013
Why have studies of tailored anti-platelet therapy failed so far?
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Ischemia; Platelet Activation; Platelet Aggregation Inhibitors; Precision Medicine; Randomized Controlled Trials as Topic; Research Design; Ticlopidine; Treatment Failure

2013
Clopidogrel is safer than ticagrelor in regard to bleeds: a closer look at the PLATO trial.
    International journal of cardiology, 2013, Oct-03, Volume: 168, Issue:3

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Hemorrhage; Humans; Incidence; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2013
Clinical applications of pharmacogenetics: present and near future.
    Cleveland Clinic journal of medicine, 2013, Volume: 80, Issue:8

    Topics: Anticoagulants; Cardiovascular Diseases; Clopidogrel; Genetic Testing; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Precision Medicine; Ticlopidine; Warfarin

2013
Indirect estimation of the comparative treatment effect in pharmacogenomic subgroups.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Cytochrome P-450 CYP2C19; Genetic Association Studies; Humans; Models, Statistical; Pharmacogenetics; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome

2013
[Informativeness of genetic factors for optimization of personalized therapy with clopidogrel].
    Kardiologiia, 2013, Volume: 53, Issue:8

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Precision Medicine; Siberia; Ticlopidine

2013
[ASA and clopidogrel for urological operations. Perioperative management].
    Der Urologe. Ausg. A, 2013, Volume: 52, Issue:11

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Ticlopidine; Urologic Surgical Procedures

2013
Thrombin-induced platelet-fibrin clot strength: relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes.
    Thrombosis and haemostasis, 2014, Apr-01, Volume: 111, Issue:4

    Topics: Aged; Aspirin; Blood Coagulation; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Fibrin; Genetic Testing; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Polymorphism, Genetic; Predictive Value of Tests; Prognosis; Thrombelastography; Thrombin; Ticlopidine; Treatment Outcome

2014
Asian study of clopidogrel (ASCLOP) responsiveness: the contributions of genetic and non-genetic factors.
    International journal of cardiology, 2014, Feb-01, Volume: 171, Issue:2

    Topics: Adult; Aged; Asian People; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Precision Medicine; Ticlopidine

2014
Residual thrombin generation potential is inversely linked to the occurrence of atherothrombotic events in patients with peripheral arterial disease.
    European journal of clinical investigation, 2014, Volume: 44, Issue:3

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Myocardial Infarction; P-Selectin; Peptide Fragments; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation Inhibitors; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, PAR-1; Recurrence; Stents; Stroke; Thrombin; Ticlopidine

2014
Highlights from the issue.
    Heart (British Cardiac Society), 2014, Volume: 100, Issue:3

    Topics: Angiotensin Receptor Antagonists; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Smoking; Socioeconomic Factors; Survival Rate; Ticlopidine

2014
Response to antiplatelet therapy and platelet reactivity to thrombin receptor activating peptide-6 in cardiovascular interventions: Differences between peripheral and coronary angioplasty.
    Atherosclerosis, 2014, Volume: 232, Issue:1

    Topics: Adenosine Diphosphate; Aged; Angioplasty; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Stents; Ticlopidine

2014
Impact of CYP2C19 polymorphism and proton pump inhibitors on platelet reactivity to clopidogrel and clinical outcomes following stent implantation.
    Thrombosis research, 2014, Volume: 133, Issue:4

    Topics: Aged; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Polymorphism, Genetic; Rabeprazole; Stents; Ticlopidine

2014
Prognosis of concomitant users of clopidogrel and proton-pump inhibitors in a high-risk population for upper gastrointestinal bleeding.
    BMC pharmacology & toxicology, 2014, Apr-15, Volume: 15

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Prognosis; Proton Pump Inhibitors; Risk; Sweden; Ticlopidine

2014
[Multination clinical trials: what is the relevance and what are the lessons from across-country differences?].
    Giornale italiano di cardiologia (2006), 2014, Volume: 15, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Americas; Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Ethnicity; Europe; Female; Georgia (Republic); Heart Failure; Humans; Internationality; Male; Metoprolol; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Russia; Sample Size; Spironolactone; Ticagrelor; Ticlopidine; Tolvaptan

2014
Appropriateness of clopidogrel use according to current recommendations.
    Family practice, 2014, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clinical Audit; Clopidogrel; Electronic Health Records; Female; Guideline Adherence; Health Care Costs; Humans; Male; Middle Aged; Nervous System Diseases; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prescription Drug Misuse; Retrospective Studies; Spain; Ticlopidine; Time Factors

2014
Benefit of clopidogrel therapy in patients with myocardial infarction and chronic kidney disease-a Danish nation-wide cohort study.
    Journal of the American Heart Association, 2014, Aug-21, Volume: 3, Issue:4

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Cohort Studies; Data Collection; Denmark; Female; Hemorrhage; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Renal Dialysis; Renal Insufficiency, Chronic; Ticlopidine; Treatment Outcome

2014
Age-related prevalence of diabetes mellitus, cardiovascular disease and anticoagulation therapy use in a urolithiasis population and their effect on outcomes: the Clinical Research Office of the Endourological Society Ureteroscopy Global Study.
    World journal of urology, 2015, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Comorbidity; Coumarins; Diabetes Mellitus; Female; Humans; Hypertension; Kidney Calculi; Male; Middle Aged; Obesity; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Prevalence; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome; Ureteral Calculi; Ureteroscopy; Urolithiasis; Young Adult

2015
Clopidogrel use as a risk factor for poor outcomes after kidney transplantation.
    American journal of surgery, 2014, Volume: 208, Issue:4

    Topics: Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Period; Prognosis; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; Ticlopidine; Tissue Donors; Transplantation, Homologous; United States

2014
Detection of clopidogrel resistance using ADP induced aggregometry with specific inhibitor PGE1.
    Clinical laboratory, 2014, Volume: 60, Issue:9

    Topics: Adenosine Diphosphate; Adult; Aged; Alprostadil; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Ticlopidine; Treatment Outcome

2014
Contemporary use of dual antiplatelet therapy for preventing cardiovascular events.
    The American journal of managed care, 2014, Volume: 20, Issue:8

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Retrospective Studies; Risk Factors; Secondary Prevention; Ticlopidine

2014
Adherence to antiplatelet therapy after percutaneous coronary intervention: a population study in a region of Italy.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2015, Volume: 16, Issue:3

    Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Italy; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine

2015
Dipstick proteinuria is an independent predictor of high on treatment platelet reactivity in patients on clopidogrel, but not aspirin, admitted for major adverse cardiovascular events.
    Platelets, 2015, Volume: 26, Issue:7

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Odds Ratio; Patient Admission; Patient Outcome Assessment; Platelet Function Tests; Proteinuria; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine

2015
Antiplatelet therapy: risks and benefits of extended DAPT after stenting.
    Nature reviews. Cardiology, 2015, Volume: 12, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Thrombosis; Ticlopidine

2015
[Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms].
    Terapevticheskii arkhiv, 2014, Volume: 86, Issue:9

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Monitoring; Drug Resistance; Drug Substitution; Drugs, Generic; Female; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Prognosis; Therapeutic Equivalency; Ticlopidine; Treatment Outcome

2014
[Changes in the diagnosis and treatment of hospitalized patients with acute coronary syndrome from 2006 to 2012 in China].
    Zhonghua xin xue guan bing za zhi, 2014, Volume: 42, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; China; Clopidogrel; Female; Hospitalization; Hospitals; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Ticlopidine

2014
Clopidogrel reduces apoptosis and promotes proliferation of human vascular endothelial cells induced by palmitic acid via suppression of the long non-coding RNA HIF1A-AS1 in vitro.
    Molecular and cellular biochemistry, 2015, Volume: 404, Issue:1-2

    Topics: Apoptosis; Cardiovascular Diseases; Cell Proliferation; China; Clopidogrel; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Palmitic Acid; RNA, Antisense; RNA, Long Noncoding; RNA, Small Interfering; Ticlopidine

2015
Association of dual-antiplatelet therapy with reduced major adverse cardiovascular events in patients with symptomatic peripheral arterial disease.
    Journal of vascular surgery, 2015, Volume: 62, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amputation, Surgical; Aspirin; California; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Critical Illness; Drug Therapy, Combination; Female; Humans; Intermittent Claudication; Ischemia; Kaplan-Meier Estimate; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Propensity Score; Proportional Hazards Models; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2015
Impact of esomeprazole on platelet reactivity and clinical outcome according to CYP2C19 genotype in coronary heart disease patients during dual antiplatelet therapy.
    Thrombosis research, 2015, Volume: 135, Issue:6

    Topics: Aged; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Esomeprazole; Ethnicity; Female; Follow-Up Studies; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome

2015
[CLINICAL AND PHARMACOLOGICAL FACTORS INFLUENCING RESISTANCE TO CLOPIDOGREL IN PATIENTS WITH CARDIOVASCULAR DISEASES].
    Klinicheskaia meditsina, 2015, Volume: 93, Issue:2

    Topics: Alleles; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; DNA; Drug Resistance; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Retrospective Studies; Thromboxane-A Synthase; Ticlopidine

2015
[The ISAR-SAFE study].
    Giornale italiano di cardiologia (2006), 2015, Volume: 16, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Disease; Coronary Restenosis; Drug Administration Schedule; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Research Design; Risk; Thrombosis; Ticlopidine

2015
Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Aspirin; Cardiac Catheterization; Cardiovascular Diseases; CD40 Ligand; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2015
Comparing prasugrel to twice daily clopidogrel post percutaneous coronary intervention in a Veterans Affairs population.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Sep-01, Volume: 72, Issue:17 Suppl 2

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Retrospective Studies; Stroke; Ticlopidine; United States; United States Department of Veterans Affairs

2015
Prior chronic clopidogrel therapy is associated with increased adverse events and early stent thrombosis.
    Thrombosis and haemostasis, 2016, Volume: 115, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Clopidogrel; Comorbidity; Coronary Artery Bypass; Female; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Stents; Stroke; Surveys and Questionnaires; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2016
Correlation between the CYP2C19 phenotype status and the results of three different platelet function tests in cardiovascular disease patients receiving antiplatelet therapy: an emphasis on newly introduced platelet function analyzer-200 P2Y test.
    Annals of laboratory medicine, 2016, Volume: 36, Issue:1

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Ticlopidine

2016
Aspirin in the prevention of cardiovascular events in patients with diabetes.
    Postgraduate medicine, 2016, Volume: 128, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Drug Administration Schedule; Half-Life; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2016
Dual platelet inhibition in cases of severe retrobulbar hemorrhage following retrobulbar and peribulbar anesthesia.
    Journal of cataract and refractive surgery, 2015, Volume: 41, Issue:10

    Topics: Aged; Anesthesia, Local; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cardiac Surgical Procedures; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Female; Humans; Lens Implantation, Intraocular; Male; Phacoemulsification; Platelet Aggregation Inhibitors; Retrobulbar Hemorrhage; Retrospective Studies; Risk Factors; Ticlopidine; Warfarin

2015
Genetic and Nongenetic Factors Affecting Clopidogrel Response in the Egyptian Population.
    Clinical and translational science, 2016, Volume: 9, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Demography; Egypt; Ethnicity; Female; Gene Frequency; Humans; Logistic Models; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Ticlopidine; Treatment Outcome

2016
Proton pump inhibitors and other disease-based factors in the recurrence of adverse cardiovascular events following percutaneous coronary angiography: A long-term cohort.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2016, Volume: 35, Issue:2

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Combinations; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Retrospective Studies; Risk; Ticlopidine; Time Factors

2016
High platelet reactivity on aspirin in patients with acute ST elevation myocardial infarction.
    Thrombosis research, 2016, Volume: 144

    Topics: Acute Disease; Adenosine; Aspirin; Blood Platelets; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; ST Elevation Myocardial Infarction; Survival Analysis; Ticagrelor; Ticlopidine

2016
[CHARISMA study].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Jun-20, Volume: 74 Suppl 4 Pt 1

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Embolism; Female; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Ticlopidine

2016
Clopidogrel pharmacogenetics: from evidence to implementation.
    Future cardiology, 2016, Volume: 12, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2016
Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acu
    Journal of the American Heart Association, 2016, 10-21, Volume: 5, Issue:10

    Topics: Acute Coronary Syndrome; Aftercare; Aged; Cardiovascular Diseases; Clopidogrel; Comparative Effectiveness Research; Female; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Recurrence; Stroke; Ticlopidine; Treatment Outcome

2016
Mortality in patients who discontinue low-dose acetylsalicylic acid therapy after upper gastrointestinal bleeding.
    Pharmacoepidemiology and drug safety, 2017, Volume: 26, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Health Care; Proportional Hazards Models; Retrospective Studies; Risk Factors; Sex Factors; Ticlopidine; Time Factors; United Kingdom

2017
Switching of adenosine diphosphate receptor inhibitor after hospital discharge among myocardial infarction patients: Insights from the Treatment with Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after
    American heart journal, 2017, Volume: 183

    Topics: Adenosine; Adenosine Diphosphate; Aged; Cardiovascular Diseases; Clopidogrel; Drug Substitution; Female; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Patient Preference; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P1 Receptor Antagonists; Ticagrelor; Ticlopidine

2017
The budget impact of using enteric-coated aspirin 325 mg + immediate-release omeprazole 40 mg to prevent recurrent cardiovascular events.
    Journal of medical economics, 2017, Volume: 20, Issue:6

    Topics: Adult; Aged; Aspirin; Budgets; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Markov Chains; Medication Adherence; Middle Aged; Models, Econometric; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine

2017
Overview of advances in cardiovascular disease treatment and prevention: the evolving role of antiplatelet therapy.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Jul-01, Volume: 65, Issue:13 Suppl 5

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clinical Protocols; Clopidogrel; Drug Therapy; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; United States

2008
Explanations for variations in clopidogrel prescribing in England.
    Journal of public health (Oxford, England), 2008, Volume: 30, Issue:4

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Prescriptions; England; Health Expenditures; Humans; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Primary Health Care; Regression Analysis; State Medicine; Ticlopidine

2008
Effects of rosuvastatin on platelet inhibition by clopidogrel in cardiovascular patients.
    Journal of thrombosis and thrombolysis, 2009, Volume: 28, Issue:2

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Pyrimidines; Retrospective Studies; Rosuvastatin Calcium; Sulfonamides; Ticlopidine

2009
Utility of the PFA-100 instrument and the novel multiplate analyzer for the assessment of aspirin and clopidogrel effects on platelet function in patients with cardiovascular disease.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2009, Volume: 15, Issue:6

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Collagen; Electric Impedance; Epinephrine; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Activation; Platelet Function Tests; Sensitivity and Specificity; Ticlopidine

2009
Anticoagulant and/or antiplatelet treatment in patients with atrial fibrillation after percutaneous coronary intervention. A single-center experience.
    Medizinische Klinik (Munich, Germany : 1983), 2008, Sep-15, Volume: 103, Issue:9

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk; Stents; Ticlopidine; Time Factors; Treatment Outcome

2008
The impact of preinjury antiplatelet and anticoagulant pharmacotherapy on outcomes in elderly patients with hemorrhagic brain injury.
    Surgery, 2008, Volume: 144, Issue:4

    Topics: Age Factors; Aged; Anticoagulants; Aspirin; Brain Hemorrhage, Traumatic; Cardiovascular Diseases; Cause of Death; Clopidogrel; Cohort Studies; Comorbidity; Female; Follow-Up Studies; Geriatric Assessment; Hospital Mortality; Humans; Injury Severity Score; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Retrospective Studies; Risk Assessment; Sex Factors; Survival Analysis; Ticlopidine; Trauma Centers; Treatment Outcome; Warfarin; Wounds, Nonpenetrating

2008
Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel.
    Journal of the American College of Cardiology, 2008, Sep-23, Volume: 52, Issue:13

    Topics: Aged; Body Mass Index; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine

2008
[Thrombocyte aggregation inhibitor after surgery for an abdominal aortic aneurysm].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:43

    Topics: Aortic Aneurysm, Abdominal; Arteriosclerosis; Aspirin; Blood Vessel Prosthesis Implantation; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Postoperative Care; Risk Factors; Thrombosis; Ticlopidine

2008
Impact of a 600-mg loading dose of clopidogrel on 30-day outcome in unselected patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2008, Nov-15, Volume: 102, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors

2008
Platelet hyperreactivity and dual antiplatelet therapy: can biases be avoided?
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:2

    Topics: Bias; Biomedical Research; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2009
The effects of clopidogrel on elderly traumatic brain injured patients.
    The Journal of trauma, 2008, Volume: 65, Issue:6

    Topics: Aged; Aspirin; Brain Damage, Chronic; Brain Injuries; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Disability Evaluation; Female; Glasgow Coma Scale; Humans; Length of Stay; Male; Platelet Aggregation Inhibitors; Prognosis; Registries; Retrospective Studies; Ticlopidine; Warfarin

2008
Cytochrome p-450 polymorphisms and response to clopidogrel.
    The New England journal of medicine, 2009, Jan-22, Volume: 360, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Angioplasty, Balloon, Coronary; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Cytochrome P-450 CYP2C19; Female; Genotype; Heterozygote; Humans; Male; Mutation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine

2009
Another view on prasugrel.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:1

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Administration Schedule; Drug Resistance; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Research Design; Risk Assessment; Stents; Thiophenes; Ticlopidine; Treatment Outcome

2009
Improving outcomes with antiplatelet therapies in percutaneous coronary intervention and stenting.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug-Eluting Stents; Hemorrhage; Humans; Patient Selection; Platelet Aggregation Inhibitors; Platelet Function Tests; Practice Guidelines as Topic; Prosthesis Design; Risk Assessment; Stents; Thrombelastography; Ticlopidine; Treatment Outcome

2009
Clopidogrel, genetics, and drug responsiveness.
    The New England journal of medicine, 2009, Jan-22, Volume: 360, Issue:4

    Topics: Acute Coronary Syndrome; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Humans; Mutation; Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2009
Platelet function analysis: at the edge of meaning.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:2

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Humans; Microfilament Proteins; Patient Selection; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reproducibility of Results; Stents; Ticlopidine

2009
Barriers to clopidogrel adherence following placement of drug-eluting stents.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:2

    Topics: Adult; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug-Eluting Stents; Exanthema; Female; Humans; Male; Medication Adherence; Platelet Aggregation Inhibitors; Ticlopidine

2009
Prognosis of patients suffering an acute coronary syndrome while already under chronic clopidogrel therapy.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Jun-01, Volume: 73, Issue:7

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2009
Multiple mechanisms affect the clopidogrel response.
    Journal of the American College of Cardiology, 2009, Mar-10, Volume: 53, Issue:10

    Topics: Biomarkers; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Diabetes Complications; Fibrinogen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2009
Summaries for patients. What aspirin dose is safest and most effective for preventing heart disease?
    Annals of internal medicine, 2009, Mar-17, Volume: 150, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Risk Factors; Thrombosis; Ticlopidine

2009
Summaries for patients. Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement.
    Annals of internal medicine, 2009, Mar-17, Volume: 150, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Risk Factors; Thrombosis; Ticlopidine

2009
Aspirin to prevent cardiovascular disease: the association of aspirin dose and clopidogrel with thrombosis and bleeding.
    Annals of internal medicine, 2009, Mar-17, Volume: 150, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Observation; Platelet Aggregation Inhibitors; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Thrombosis; Ticlopidine

2009
PCI, stents, clopidogrel and non-cardiac surgery.
    Clinical cardiology, 2009, Volume: 32, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stents; Surgical Procedures, Operative; Ticlopidine

2009
Dual antiplatelet drug resistance is a risk factor for cardiovascular events after percutaneous coronary intervention.
    Clinical chemistry, 2009, Volume: 55, Issue:6

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2009
Measurement of platelet P-selectin for remote testing of platelet function during treatment with clopidogrel and/or aspirin.
    Platelets, 2009, Volume: 20, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aspirin; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Drug Monitoring; Female; Flow Cytometry; Humans; Male; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Tissue Fixation

2009
Evidence guided antiplatelet treatment: time to move from bench to bedside.
    Thrombosis research, 2009, Volume: 124, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Drug Therapy; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine

2009
Acknowledging a failed strategy.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Jun-01, Volume: 73, Issue:7

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Hospital Mortality; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Failure; Treatment Outcome

2009
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone for secondary prevention of cardiovascular events: results from the CHARISMA trial.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2009, Volume: 12, Issue:6

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Databases, Factual; Drug Therapy, Combination; Female; Health Care Costs; Hospitalization; Humans; Life Expectancy; Male; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Saskatchewan; Secondary Prevention; Survival Analysis; Ticlopidine; United States

2009
[Cardiology 2009].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:25-26

    Topics: Aryl Hydrocarbon Hydroxylases; Atrial Fibrillation; Cardiology; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Exercise; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stroke Volume; Ticlopidine

2009
New findings highlight potential risks of common drug combination in cardiac patients.
    Healthcare quarterly (Toronto, Ont.), 2009, Volume: 12, Issue:3

    Topics: Cardiovascular Diseases; Clopidogrel; Contraindications; Drug Interactions; Drug Therapy, Combination; Humans; Proton Pump Inhibitors; Ticlopidine

2009
Premature preoperative discontinuation of antiplatelet drug therapy in cardiovascular risk patients: a preliminary study on the role of P2Y12 receptor monitoring.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:2

    Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Function Tests; Preoperative Care; Prospective Studies; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Time Factors

2010
Calcium-channel blockers decrease clopidogrel-mediated platelet inhibition.
    Heart (British Cardiac Society), 2010, Volume: 96, Issue:3

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine

2010
Cardiovascular disease gets personal.
    Nature, 2009, Aug-20, Volume: 460, Issue:7258

    Topics: Anticoagulants; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Female; Genetic Predisposition to Disease; Genetic Testing; Genetic Variation; Genome-Wide Association Study; Genomics; Humans; Pharmacogenetics; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Warfarin

2009
Comparison of bleeding complications with omega-3 fatty acids + aspirin + clopidogrel--versus--aspirin + clopidogrel in patients with cardiovascular disease.
    The American journal of cardiology, 2009, Oct-15, Volume: 104, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; United States

2009
Adenosine diphosphate-inducible platelet reactivity shows a pronounced age dependency in the initial phase of antiplatelet therapy with clopidogrel.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:1

    Topics: Adenosine Diphosphate; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon; Blood Platelets; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Female; Humans; Linear Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Stents; Ticlopidine

2010
A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding.
    Clinical therapeutics, 2009, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Databases, Factual; Drug Costs; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Patient Readmission; Peptic Ulcer; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Secondary Prevention; Taiwan; Ticlopidine

2009
The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy.
    American heart journal, 2009, Volume: 158, Issue:5

    Topics: Adult; Aged; Aspirin; Blood Glucose; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2009
Prasugrel: new drug. After angioplasty and stenting: continue to use aspirin + clopidogrel.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Europe; Hemorrhage; Humans; Ischemic Attack, Transient; Myocardial Infarction; Neoplasms; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Recurrence; Stents; Stroke; Thiophenes; Ticlopidine; Treatment Outcome

2009
Women are like men ... Sometimes.
    Journal of the American College of Cardiology, 2009, Nov-17, Volume: 54, Issue:21

    Topics: Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Prevalence; Sex Factors; Ticlopidine; Treatment Outcome

2009
Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome.
    Circulation, 2009, Dec-08, Volume: 120, Issue:23

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Databases, Factual; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Proton Pump Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome

2009
[Proton pump inhibitors and clopidogrel in a patient with cardiovascular risk factors: Cardiovascular versus gastrointestinal risk?].
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:1

    Topics: Algorithms; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Diseases; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine

2010
The right oral antithrombotics in acute coronary syndromes.
    Lancet (London, England), 2009, Dec-12, Volume: 374, Issue:9706

    Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Vitamin K

2009
Frontiers in platelet inhibition.
    Discovery medicine, 2009, Volume: 8, Issue:43

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Models, Biological; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Ticlopidine

2009
Benefit assessment in Germany.
    The New England journal of medicine, 2010, Jan-28, Volume: 362, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Comparative Effectiveness Research; Germany; Government Agencies; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; National Health Programs; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2010
Serum thromboxane B2 compared to five other platelet function tests for the evaluation of aspirin effect in stable cardiovascular disease.
    Heart, lung & circulation, 2010, Volume: 19, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Female; Fish Oils; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Statistics as Topic; Statistics, Nonparametric; Surveys and Questionnaires; Thromboxane B2; Ticlopidine

2010
Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are needed.
    Journal of clinical epidemiology, 2010, Volume: 63, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; England; Evidence-Based Medicine; Germany; Humans; Intention to Treat Analysis; Randomized Controlled Trials as Topic; Research Design; Ticlopidine

2010
[Cardiac workup after cerebral ischemia. Consensus paper of the Working Group on Heart and Brain of the German Cardiac Society and German Stroke Society].
    Der Nervenarzt, 2010, Volume: 81, Issue:4

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Embolism; Exercise Test; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Warfarin

2010
Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study.
    Annals of internal medicine, 2010, Mar-16, Volume: 152, Issue:6

    Topics: Adult; Aged; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2010
Propensity score adjustment with multilevel data: setting your sites on decreasing selection bias.
    Annals of internal medicine, 2010, Mar-16, Volume: 152, Issue:6

    Topics: Cardiovascular Diseases; Clopidogrel; Data Interpretation, Statistical; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Proton Pump Inhibitors; Selection Bias; Ticlopidine

2010
Prasugrel, Māori, and personalised medicine in New Zealand.
    The New Zealand medical journal, 2010, Mar-05, Volume: 123, Issue:1310

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genetic Markers; Genetic Testing; Humans; Native Hawaiian or Other Pacific Islander; Pharmacogenetics; Piperazines; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Precision Medicine; Stents; Thiophenes; Thrombosis; Ticlopidine; Vascular Diseases

2010
Delays in filling clopidogrel prescription after hospital discharge and adverse outcomes after drug-eluting stent implantation: implications for transitions of care.
    Circulation. Cardiovascular quality and outcomes, 2010, Volume: 3, Issue:3

    Topics: Cardiovascular Diseases; Chemotherapy, Adjuvant; Clopidogrel; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Medication Therapy Management; Myocardial Infarction; Patient Compliance; Patient Discharge; Platelet Aggregation Inhibitors; Postoperative Complications; Prescriptions; Prosthesis Implantation; Retrospective Studies; Risk Factors; Survival Analysis; Ticlopidine; United States

2010
Withdrawal of clopidogrel in active gastric bleeding.
    Annals of internal medicine, 2010, May-18, Volume: 152, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platelet Aggregation Inhibitors; Research Design; Ticlopidine

2010
Glycemic control and clopidogrel response.
    American heart journal, 2010, Volume: 159, Issue:6

    Topics: Blood Glucose; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus; Glycated Hemoglobin; Glycemic Index; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine

2010
[Clopidogrel and its salts: any clnical implication?].
    Revue medicale suisse, 2010, Jun-02, Volume: 6, Issue:251

    Topics: Atracurium; Cardiovascular Diseases; Chloral Hydrate; Clinical Trials as Topic; Clopidogrel; Humans; Hypnotics and Sedatives; Nicotinic Agonists; Platelet Aggregation; Platelet Aggregation Inhibitors; Therapeutic Equivalency; Ticlopidine

2010
ACCF/AHA Clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association.
    Circulation, 2010, Aug-03, Volume: 122, Issue:5

    Topics: American Heart Association; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Contraindications; Cytochrome P-450 CYP2C19; Drug Labeling; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Ticlopidine; United States

2010
Peptic disease: a confounding factor for proton pump inhibitor-clopidogrel interaction?
    The American journal of cardiology, 2010, Jul-15, Volume: 106, Issue:2

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2010
Post-thienopyridine platelet response, cardiovascular outcomes, and personalized therapy: En attendant Godot.
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Biomarkers; Blood Platelets; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Drug-Eluting Stents; Flow Cytometry; Humans; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Precision Medicine; Predictive Value of Tests; Prosthesis Design; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2010
Impact of P2Y12 inhibition by clopidogrel on cardiovascular mortality in unselected patients treated by percutaneous coronary angioplasty: a prospective registry.
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; Blood Platelets; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Drug-Eluting Stents; Female; Flow Cytometry; France; Humans; Kaplan-Meier Estimate; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Registries; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2010
Letter by Aboyans et al regarding article, "Smoking, clopidogrel, and mortality in patients with established cardiovascular disease".
    Circulation, 2010, Jul-20, Volume: 122, Issue:3

    Topics: Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Smoking; Ticlopidine

2010
Impact of proton pump inhibitors on the effectiveness of clopidogrel after coronary stent placement: the clopidogrel Medco outcomes study.
    Pharmacotherapy, 2010, Volume: 30, Issue:8

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Synergism; Drug Therapy, Combination; Female; Hospitalization; Humans; Male; Middle Aged; Proton Pump Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome

2010
Impact of inflammatory markers on platelet inhibition and cardiovascular outcome including stent thrombosis in patients with symptomatic coronary artery disease.
    Atherosclerosis, 2010, Volume: 213, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon; Aspirin; Blood Platelets; C-Reactive Protein; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Inflammation; Male; Pilot Projects; Platelet Activation; Stents; Ticlopidine; Treatment Outcome

2010
The influence of proton pump inhibitors on the antiplatelet potency of clopidogrel evaluated by 5 different platelet function tests.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine

2010
Cardiovascular and gastrointestinal outcomes in clopidogrel users on proton pump inhibitors: results of a large Dutch cohort study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:11

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Databases, Factual; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Netherlands; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome

2010
Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis.
    Lancet (London, England), 2010, Oct-16, Volume: 376, Issue:9749

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genetic Variation; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Thiophenes; Ticlopidine

2010
Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial.
    Lancet (London, England), 2010, Oct-16, Volume: 376, Issue:9749

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Pharmacogenetics; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Randomized Controlled Trials as Topic; Ticagrelor; Ticlopidine

2010
Cardiovascular and gastrointestinal events of three antiplatelet therapies: clopidogrel, clopidogrel plus proton-pump inhibitors, and aspirin plus proton-pump inhibitors in patients with previous gastrointestinal bleeding.
    Journal of gastroenterology, 2011, Volume: 46, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Agents; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk; Taiwan; Ticlopidine; Treatment Outcome

2011
Fine-tuning therapy for acute coronary syndromes.
    The New England journal of medicine, 2010, Sep-02, Volume: 363, Issue:10

    Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Angiography; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2010
Protective effect of the CYP2C19 *17 polymorphism with increased activation of clopidogrel on cardiovascular events.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Aged; Alleles; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cardiovascular Diseases; Clopidogrel; Coronary Angiography; Coronary Restenosis; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Recurrence; Reoperation; Stents; Stroke; Ticlopidine

2010
Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:6

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; C-Reactive Protein; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinogen; Germany; Humans; Inflammation Mediators; Leukocyte Count; Linear Models; Logistic Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2010
Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use: a nationwide cohort study.
    Annals of internal medicine, 2010, Sep-21, Volume: 153, Issue:6

    Topics: Adult; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Interactions; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Recurrence; Regression Analysis; Risk Factors; Ticlopidine; Time Factors

2010
Conflicting evidence: what's a clinician to do?
    Annals of internal medicine, 2010, Sep-21, Volume: 153, Issue:6

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine

2010
[The PLATO study].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:5

    Topics: Acute Coronary Syndrome; Adenosine; Cardiovascular Diseases; Clopidogrel; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticagrelor; Ticlopidine

2010
Clinical predictors of dual aspirin and clopidogrel poor responsiveness in stable cardiovascular patients from the ADRIE study.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:12

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Purinergic P2Y Receptor Antagonists; Ticlopidine

2010
Increased use of acid-suppressing drugs before the occurrence of ischemic events: a potential source of confounding in recent observational studies.
    Pharmacotherapy, 2010, Volume: 30, Issue:10

    Topics: Adult; Aged; Angina, Unstable; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Confounding Factors, Epidemiologic; Drug Therapy, Combination; Epidemiologic Studies; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Research Design; Risk Factors; Ticlopidine; Time Factors

2010
Use of genetics and transcriptomics in the diagnosis and treatment of coronary artery disease.
    Revista espanola de cardiologia, 2010, Volume: 63, Issue:10

    Topics: Anticoagulants; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Gene Expression Profiling; Genetic Testing; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin

2010
Comparison of hemorrhagic complications of warfarin and clopidogrel bisulfate in 25-gauge vitrectomy versus a control group.
    Ophthalmology, 2011, Volume: 118, Issue:3

    Topics: Aged; Anticoagulants; Cardiovascular Diseases; Choroid Hemorrhage; Clopidogrel; Humans; Incidence; Intraocular Pressure; Intraoperative Complications; Microsurgery; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Retinal Diseases; Retrobulbar Hemorrhage; Retrospective Studies; Risk Factors; Ticlopidine; Visual Acuity; Vitrectomy; Vitreous Hemorrhage; Warfarin

2011
No inconsistent trial assessments by NICE and IQWiG: different assessment goals may lead to different assessment results regarding subgroup analyses.
    Journal of clinical epidemiology, 2010, Volume: 63, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; England; Evidence-Based Medicine; Germany; Humans; Prescription Drugs; Randomized Controlled Trials as Topic; Research Design; Ticlopidine

2010
Impact of concomitant treatment with proton pump inhibitors and clopidogrel on clinical outcome in patients after coronary stent implantation.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Patient Readmission; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Proton Pump Inhibitors; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2010
Clopidogrel and the reduced-function CYP2C19 genetic variant: a limited piece of the overall therapeutic puzzle.
    JAMA, 2010, Oct-27, Volume: 304, Issue:16

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Humans; Patient Selection; Pharmacogenetics; Platelet Aggregation Inhibitors; Risk; Stents; Ticlopidine

2010
Resistance to aspirin and clopidogrel therapy.
    International journal of laboratory hematology, 2011, Volume: 33, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2011
Interaction of clopidogrel and omeprazole.
    The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20

    Topics: Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2010
Impact of CYP2C19 polymorphism on residual platelet reactivity in patients with coronary heart disease during antiplatelet therapy.
    Journal of cardiology, 2011, Volume: 57, Issue:2

    Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Asian People; Cardiovascular Diseases; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Endovascular Procedures; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stents; Ticlopidine

2011
[Better understanding of combination use of clopidogrel and proton pump inhibitor].
    Zhonghua nei ke za zhi, 2010, Volume: 49, Issue:12

    Topics: Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Proton Pump Inhibitors; Ticlopidine

2010
[Renal artery stenosis: angioplasty or drug treatment?].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:3

    Topics: Aged; Angioplasty; Anticoagulants; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Combined Modality Therapy; Creatinine; Diagnostic Imaging; Female; Follow-Up Studies; Germany; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Renovascular; Male; Middle Aged; Renal Artery Obstruction; Renal Dialysis; Retrospective Studies; Risk Factors; Survival Rate; Ticlopidine

2011
[Antiplatelet agents and diabetes mellitus].
    Annales de cardiologie et d'angeiologie, 2010, Volume: 59 Suppl 2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2010
Double-dose clopidogrel in patients undergoing PCI for ACS.
    Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2011
Double-dose clopidogrel in patients undergoing PCI for ACS.
    Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2011
Carriage of reduced-function CYP2C19 allele among patients treated with clopidogrel.
    JAMA, 2011, Feb-02, Volume: 305, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Bias; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Publication Bias; Reproducibility of Results; Ticlopidine

2011
Clopidogrel with or without omeprazole in coronary disease.
    The New England journal of medicine, 2011, 02-17, Volume: 364, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Cardiovascular Diseases; Chemistry, Pharmaceutical; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Pantoprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2011
Clopidogrel: to test or not to test? That is the question--still.
    Clinical chemistry, 2011, Volume: 57, Issue:5

    Topics: Aryl Hydrocarbon Hydroxylases; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genetic Testing; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Precision Medicine; Ticlopidine; United States; United States Food and Drug Administration

2011
An initial experiment with personalized antiplatelet therapy: the GRAVITAS trial.
    JAMA, 2011, Mar-16, Volume: 305, Issue:11

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Randomized Controlled Trials as Topic; Risk; Thrombosis; Ticlopidine

2011
[Does combination therapy of aspirin plus antiplatelet therapy increase the risk of upper gastrointestinal hemorrhage?].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, Volume: 57, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2011
[The effect of aspirin alone or aspirin plus additional antiplatelets therapy on upper gastrointestinal hemorrhage].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, Volume: 57, Issue:4

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine

2011
Optimizing of thienopyridine therapy by multiple electrode platelet aggregometry in clopidogrel low responders undergoing PCI.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2011, Volume: 100, Issue:10

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Cerebrovascular Disorders; Cilostazol; Clopidogrel; Drug Monitoring; Drug Resistance; Drug Substitution; Electrodes; Female; Germany; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; Stents; Tetrazoles; Thiophenes; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2011
[The CURRENT-OASIS 7 study].
    Giornale italiano di cardiologia (2006), 2011, Volume: 12, Issue:3

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Confidence Intervals; Drug Administration Schedule; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Salivary Ducts; Thrombosis; Ticlopidine

2011
Clopidogrel response variability and its correlation with early recurrent cardiovascular events in chinese patients undergoing percutaneous coronary intervention.
    Pharmacology, 2011, Volume: 87, Issue:5-6

    Topics: Aged; Angioplasty, Balloon, Coronary; Asian People; Cardiovascular Diseases; Clopidogrel; Female; Humans; Individuality; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Stents; Ticlopidine; Treatment Outcome

2011
Clopidogrel loading dose in patients undergoing elective percutaneous coronary intervention.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:13

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2011
Oral antiplatelet agents clopidogrel and prasugrel for the prevention of cardiovascular events.
    BMJ (Clinical research ed.), 2011, Jun-17, Volume: 342

    Topics: Administration, Oral; Cardiovascular Diseases; Clopidogrel; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2011
Standard- vs high-dose clopidogrel after percutaneous coronary intervention.
    JAMA, 2011, Jun-22, Volume: 305, Issue:24

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Reproducibility of Results; Risk; Ticlopidine

2011
The prevalence of co-administration of clopidogrel and proton pump inhibitors.
    Quality in primary care, 2011, Volume: 19, Issue:1

    Topics: Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Drug Utilization Review; Female; Gastrointestinal Hemorrhage; Humans; Male; New South Wales; Nursing Homes; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine

2011
[Clopidogrel and proton pump inhibitors: insufficient evidence of interaction].
    Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155, Issue:28

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Drug Interactions; Gastrointestinal Diseases; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2011
Non-cardiac surgery in patients with coronary stents: the RECO study.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:19

    Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; France; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Risk Assessment; Risk Factors; Stents; Surgical Procedures, Operative; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2011
Dual oral antiplatelet therapy and unplanned surgery: possible role for intravenous platelet glycoprotein receptor inhibitors.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2011, Volume: 12, Issue:9

    Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Biliary Tract Surgical Procedures; Cardiovascular Diseases; Cholangitis; Choledocholithiasis; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Humans; Infusions, Intravenous; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine

2011
Relationship between cardiovascular outcomes and proton pump inhibitor use in patients receiving dual antiplatelet therapy after acute coronary syndrome.
    Pharmacoepidemiology and drug safety, 2011, Volume: 20, Issue:10

    Topics: Acute Coronary Syndrome; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Databases, Factual; Drug Interactions; Esomeprazole; Female; Herb-Drug Interactions; Hospitalization; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Retrospective Studies; Ticlopidine; Treatment Outcome

2011
Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cardiovascular Diseases; Child; Child, Preschool; Clopidogrel; Cohort Studies; Denmark; Drug Interactions; Felodipine; Female; Humans; Infant; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk; Stents; Ticlopidine; Verapamil; Young Adult

2012
Ticagrelor (Brilinta)--better than clopidogrel (Plavix)?
    The Medical letter on drugs and therapeutics, 2011, Sep-05, Volume: 53, Issue:1372

    Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Approval; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Thiophenes; Ticagrelor; Ticlopidine; United States

2011
PON1 Q192R and clopidogrel: a case of the winner's curse or inadequate replication?
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:6

    Topics: Aryldialkylphosphatase; Cardiovascular Diseases; Female; Genetic Association Studies; Genetic Variation; Humans; Male; Myocardial Infarction; Polymorphism, Genetic; Ticlopidine

2011
Unveiling the mysteries of clopidogrel metabolism and efficacy.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:6

    Topics: Aryldialkylphosphatase; Cardiovascular Diseases; Female; Genetic Association Studies; Genetic Variation; Humans; Male; Myocardial Infarction; Polymorphism, Genetic; Ticlopidine

2011
Pharmacogenomics and clopidogrel: irrational exuberance?
    JAMA, 2011, Dec-28, Volume: 306, Issue:24

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2011
Frequency of heparin/platelet factor 4-dependent platelet antibodies in patients undergoing angioplasty and stenting for cardiovascular disease and their role for on-clopidogrel platelet reactivity.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2012, Volume: 101, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies; Anticoagulants; Cardiovascular Diseases; Clopidogrel; Enzyme-Linked Immunosorbent Assay; Heparin; Humans; Immunoassay; Immunoglobulin G; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Factor 4; Stents; Ticlopidine

2012
Concomitant use of clopidogrel and statins and risk of major adverse cardiovascular events following coronary stent implantation.
    British journal of clinical pharmacology, 2012, Volume: 74, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Denmark; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Regression Analysis; Risk Factors; Stents; Ticlopidine; Time Factors

2012
Phenotyping vs. genotyping for prediction of clopidogrel efficacy and safety: the PEGASUS-PCI study.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Austria; Blood Platelets; Cardiovascular Diseases; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Hemorrhage; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Microfilament Proteins; Middle Aged; Multivariate Analysis; Pharmacogenetics; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2012
New look at antiplatelet agent-related peptic ulcer: an update of prevention and treatment.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Peptic Ulcer; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Thiophenes; Ticlopidine

2012
Predictors and time trends in clopidogrel and proton pump inhibitor coprescription with low-dose acetylsalicylic acid.
    Pharmacoepidemiology and drug safety, 2012, Volume: 21, Issue:5

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Primary Health Care; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; United Kingdom

2012
Dual non-responsiveness to antiplatelet treatment is a stronger predictor of cardiac adverse events than isolated non-responsiveness to clopidogrel or aspirin.
    International journal of cardiology, 2013, Jul-31, Volume: 167, Issue:2

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Ticlopidine; Treatment Outcome

2013
Is there a clinically significant interaction between calcium channel antagonists and clopidogrel?: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial.
    Circulation. Cardiovascular interventions, 2012, Feb-01, Volume: 5, Issue:1

    Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Survival Analysis; Ticlopidine

2012
Clopidogrel dosing based on genotype.
    JAMA, 2012, Mar-14, Volume: 307, Issue:10

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine

2012
Adverse cardiovascular outcomes associated with concurrent use of clopidogrel or ticlopidine and proton-pump inhibitors in patients undergoing percutaneous coronary intervention.
    Heart and vessels, 2013, Volume: 28, Issue:3

    Topics: Aged; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Coronary Stenosis; Disease-Free Survival; Drug Interactions; Female; Hospitals, University; Humans; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polypharmacy; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2013
Cost-effectiveness of cytochrome P450 2C19 genotype screening for selection of antiplatelet therapy with clopidogrel or prasugrel.
    Pharmacotherapy, 2012, Volume: 32, Issue:4

    Topics: Acute Coronary Syndrome; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Cytochrome P-450 CYP2C19; Decision Trees; Drugs, Generic; Genotype; Hemorrhage; Humans; Models, Economic; Models, Statistical; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Thrombolytic Therapy; Ticlopidine

2012
CYP2C19 genotype and cardiovascular events.
    JAMA, 2012, Apr-11, Volume: 307, Issue:14

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2012
CYP2C19 genotype and cardiovascular events.
    JAMA, 2012, Apr-11, Volume: 307, Issue:14

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2012
CYP2C19 genotype and cardiovascular events.
    JAMA, 2012, Apr-11, Volume: 307, Issue:14

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2012
Pharmacokinetic interactions between clopidogrel and rosuvastatin: effects on vascular protection in subjects with coronary heart disease.
    International journal of cardiology, 2012, Jun-28, Volume: 158, Issue:1

    Topics: Cardiovascular Diseases; Clopidogrel; Coronary Disease; Drug Interactions; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Ticlopidine

2012
Major adverse cardiac events among postpercutaneous coronary intervention patients on clopidogrel and proton pump inhibitors.
    Connecticut medicine, 2012, Volume: 76, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine

2012
P2Y12 inhibitors in acute coronary syndromes: how do we choose the best drug for our patients?
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:2

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Humans; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticagrelor; Ticlopidine

2012
Effect of the clopidogrel-proton pump inhibitor drug interaction on adverse cardiovascular events in patients with acute coronary syndrome.
    Pharmacotherapy, 2012, Volume: 32, Issue:9

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Interactions; Female; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Regression Analysis; Retrospective Studies; Ticlopidine; Time Factors

2012
Clopidogrel efficacy and cigarette smoking status.
    JAMA, 2012, Jun-20, Volume: 307, Issue:23

    Topics: Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP1A2; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Smoking; Stroke; Ticlopidine; Treatment Failure

2012
Clopidogrel versus aspirin in patients with atherothrombosis: a CAPRIE-based cost-effectiveness model for Greece.
    Applied health economics and health policy, 2012, Sep-01, Volume: 10, Issue:5

    Topics: Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Greece; Humans; Models, Economic; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Secondary Prevention; Thrombosis; Ticlopidine; Treatment Outcome

2012
Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes.
    JAMA, 2012, Sep-05, Volume: 308, Issue:9

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Data Collection; Denmark; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Mortality; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Registries; Risk; Ticlopidine

2012
Antiplatelet therapy following myocardial infarction in patients with diabetes.
    JAMA, 2012, Sep-05, Volume: 308, Issue:9

    Topics: Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine

2012
Gastrointestinal events with clopidogrel: a nationwide population-based cohort study.
    Journal of general internal medicine, 2013, Volume: 28, Issue:2

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Denmark; Dose-Response Relationship, Drug; Drug Utilization; Female; Gastritis; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine

2013
Influence of smoking on treatment with clopidogrel.
    JAMA, 2012, Oct-03, Volume: 308, Issue:13

    Topics: Cardiovascular Diseases; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2012
Clinical-scientific notes.
    Internal medicine journal, 2012, Volume: 42 Suppl 5

    Topics: Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Genotype; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2012
The impact of reducing cardiovascular medication copayments on health spending and resource utilization.
    Journal of the American College of Cardiology, 2012, Oct-30, Volume: 60, Issue:18

    Topics: Aged; Cardiology; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Cost Sharing; Drug Therapy; Evidence-Based Medicine; Female; Health Care Costs; Health Care Reform; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insurance, Health; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Ticlopidine; Treatment Outcome

2012
Statements of the Malaysian Society of Gastroenterology & Hepatology and the National Heart Association of Malaysia task force 2012 working party on the use of antiplatelet therapy and proton pump inhibitors in the prevention of gastrointestinal bleeding.
    Journal of digestive diseases, 2013, Volume: 14, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Malaysia; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2013
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:8

    Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6

2012
Management and outcomes of patients on preoperative plavix (clopidogrel) undergoing general thoracic surgery.
    The Thoracic and cardiovascular surgeon, 2013, Volume: 61, Issue:6

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Substitution; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Propensity Score; Reoperation; Retrospective Studies; Risk Factors; Thoracic Surgical Procedures; Ticlopidine; Time Factors; Treatment Outcome

2013
Historical lessons in translational medicine: cyclooxygenase inhibition and P2Y12 antagonism.
    Circulation research, 2013, Jan-04, Volume: 112, Issue:1

    Topics: Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance; Evidence-Based Medicine; History, 20th Century; History, 21st Century; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine; Translational Research, Biomedical

2013
Treatment with clopidogrel after myocardial infarction.
    JAMA, 2012, Dec-19, Volume: 308, Issue:23

    Topics: Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine

2012
Treatment with clopidogrel after myocardial infarction.
    JAMA, 2012, Dec-19, Volume: 308, Issue:23

    Topics: Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine

2012
Characterization of aspirin allergies in patients with coronary artery disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013, Volume: 110, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; California; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Female; Humans; Male; Retrospective Studies; Ticlopidine

2013
Factors that contribute to clopidogrel resistance in cardiovascular disease patients: environmental and genetic approach.
    International journal of clinical pharmacology and therapeutics, 2013, Volume: 51, Issue:3

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Cardiovascular Diseases; Cholesterol, HDL; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine

2013
Comparing the safety of ticagrelor versus clopidogrel: insights from the FDA reports.
    Therapeutic advances in cardiovascular disease, 2013, Volume: 7, Issue:1

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Humans; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; United States; United States Food and Drug Administration

2013
Aspirin therapy should be first-line treatment in secondary prevention of stroke--against.
    Stroke, 2002, Volume: 33, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Stroke; Ticlopidine; Treatment Outcome

2002
Thrombotic thrombocytopenic purpura associated with ticlopidine.
    Acta haematologica, 2003, Volume: 109, Issue:1

    Topics: Cardiovascular Diseases; Female; Fibrinolytic Agents; Humans; Middle Aged; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ticlopidine; Treatment Outcome

2003
[Anticoagulation and antiaggregation in cardiac patients].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:1

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Heart Valve Prosthesis; Hemorrhage; Humans; Myocardial Infarction; Placebos; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thromboembolism; Ticlopidine

2003
[New antiaggregants and their importance for the practitioner].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:1

    Topics: Abciximab; Administration, Oral; Adult; Anesthesia, Spinal; Antibodies, Monoclonal; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Contraindications; Drug Therapy, Combination; Eptifibatide; Female; Fibrinolytic Agents; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Peptides; Placebos; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pregnancy; Ticlopidine; Tirofiban; Tyrosine

2003
Are antiplatelet effects of clopidogrel inhibited by atorvastatin? A research question formulated but not yet adequately tested.
    Circulation, 2003, Apr-01, Volume: 107, Issue:12

    Topics: Atorvastatin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Pyrroles; Research; Ticlopidine

2003
By the way, doctor. A new television ad says I should ask my doctor about Plavix, a drug that reduces the risk of heart attack and stroke. I'm 65 years old and healthy. Should I be taking Plavix preventively?
    Harvard women's health watch, 2003, Volume: 11, Issue:3

    Topics: Aged; Cardiovascular Diseases; Clopidogrel; Female; Health Status; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2003
Aspirin for cardiovascular disease prevention.
    The Medical journal of Australia, 2004, Jan-19, Volume: 180, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2004
Guidelines on the management of secondary prophylaxis of vascular events in stable patients in primary care.
    International journal of clinical practice, 2004, Volume: 58, Issue:2

    Topics: Acute Disease; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Dipyridamole; Endarterectomy, Carotid; Humans; Life Style; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stents; Ticlopidine; Treatment Outcome

2004
Aspirin or clopidogrel for secondary prevention of cardiovascular events: is there a winner?
    The American journal of medicine, 2004, Jun-15, Volume: 116, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2004
Clinical significance of the atorvastatin-clopidogrel drug-drug interaction.
    Circulation, 2004, Aug-10, Volume: 110, Issue:6

    Topics: Atorvastatin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Sample Size; Ticlopidine

2004
[Cardiovascular pharmacology].
    Der Internist, 2004, Volume: 45, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Fatty Acids, Omega-3; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine

2004
Clopidogrel (Plavix) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding.
    Platelets, 2004, Volume: 15, Issue:5

    Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Postoperative Hemorrhage; Purinergic P2 Receptor Antagonists; Retrospective Studies; Thrombelastography; Ticlopidine; Time Factors

2004
[After coronary stenting course of ticlopidine (1 month) compared with that of clopidogrel was associated with significantly lower cardiovascular mortality during 28 moths follow up].
    Kardiologiia, 2004, Volume: 44, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Data Interpretation, Statistical; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Time Factors

2004
Variability in platelet responsiveness to clopidogrel among 544 individuals.
    Journal of the American College of Cardiology, 2005, Jan-18, Volume: 45, Issue:2

    Topics: Aged; Antigens, CD; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors

2005
Reducing the risks of gastrointestinal bleeding with antiplatelet therapies.
    The New England journal of medicine, 2005, Jan-20, Volume: 352, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2005
Summaries for patients. Is it cost-effective to treat high-risk cardiac patients with clopidogrel plus aspirin as opposed to aspirin alone?
    Annals of internal medicine, 2005, Feb-15, Volume: 142, Issue:4

    Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine

2005
A cost-effectiveness analysis of combination antiplatelet therapy for high-risk acute coronary syndromes: clopidogrel plus aspirin versus aspirin alone.
    Annals of internal medicine, 2005, Feb-15, Volume: 142, Issue:4

    Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Electrocardiography; Hemorrhage; Humans; Markov Chains; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Recurrence; Risk Factors; Sensitivity and Specificity; Stroke; Ticlopidine

2005
Clopidogrel versus aspirin and esomeprazole to prevent recurrent bleeding.
    The New England journal of medicine, 2005, Apr-21, Volume: 352, Issue:16

    Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine

2005
[Aspirin and cardiovascular prevention: last minute information].
    Revue medicale de Liege, 2005, Volume: 60, Issue:3

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Ticlopidine

2005
[Highlights from the American College of Cardiology Annual Scientific Session 2005: March 5-9, 2005, Orlando, Florida].
    Revue medicale suisse, 2005, May-04, Volume: 1, Issue:18

    Topics: Aspirin; Cardiovascular Diseases; Cholesterol, LDL; Clopidogrel; Humans; Hypercholesterolemia; Obesity; Piperidines; Platelet Aggregation Inhibitors; Pyrazoles; Rimonabant; Stroke; Ticlopidine

2005
Appropriate use of antiplatelets: is prescription in daily practice influenced by the global cardiovascular risk?
    European journal of clinical pharmacology, 2005, Volume: 61, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Drug Utilization; Female; Humans; Italy; Male; Middle Aged; Physicians, Family; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Primary Prevention; Risk Assessment; Ticlopidine

2005
Clopidogrel linking evaluation of platelet response variability to mechanism of action.
    Journal of the American College of Cardiology, 2005, Aug-16, Volume: 46, Issue:4

    Topics: Blood Platelets; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Time Factors; Treatment Outcome

2005
Clopidogrel "resistance" and statin cotreatment - significant for cardiocoronary prevention in real life?
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:2

    Topics: Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2005
Molecular mechanism of Clopidogrel and Aspirin therapy-induced bleeding episodes.
    Medical hypotheses, 2006, Volume: 66, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Eicosanoids; Hemorrhage; Humans; Ticlopidine

2006
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone.
    Annals of internal medicine, 2005, Sep-20, Volume: 143, Issue:6

    Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2005
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone.
    Annals of internal medicine, 2005, Sep-20, Volume: 143, Issue:6

    Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2005
[ASS or clopidogrel plus esomeprazole after bleeding from an ulcer].
    Der Internist, 2005, Volume: 46, Issue:12

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine

2005
The charisma of subgroups and the subgroups of CHARISMA.
    The New England journal of medicine, 2006, Apr-20, Volume: 354, Issue:16

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Confidence Intervals; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2006
Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril and enalapril.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95, Issue:4

    Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Cardiovascular Diseases; Clopidogrel; Collagen; Coronary Artery Disease; Electric Impedance; Enalapril; Female; Fibrinolytic Agents; Germany; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ramipril; Ticlopidine; Treatment Outcome

2006
Clopidogrel (Plavix) revisited.
    The Medical letter on drugs and therapeutics, 2006, Apr-10, Volume: 48, Issue:1232

    Topics: Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2006
Aspirin and clopidogrel resistance: an emerging clinical entity.
    European heart journal, 2006, Volume: 27, Issue:14

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2006
Sub-Tenon's anesthesia with aspirin, warfarin, and clopidogrel.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anticoagulants; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Conjunctival Diseases; Connective Tissue; Eye Hemorrhage; Female; Humans; Lens Implantation, Intraocular; Male; Medical Audit; Middle Aged; Phacoemulsification; Prospective Studies; Risk Factors; Ticlopidine; Warfarin

2006
Aspirin and clopidogrel resistance.
    Mayo Clinic proceedings, 2006, Volume: 81, Issue:7

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance, Multiple; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2006
Clopidogrel for the prevention of atherothrombotic events.
    The New England journal of medicine, 2006, Jul-27, Volume: 355, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Research Design; Ticlopidine

2006
Clopidogrel for the prevention of atherothrombotic events.
    The New England journal of medicine, 2006, Jul-27, Volume: 355, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2006
Clopidogrel for the prevention of atherothrombotic events.
    The New England journal of medicine, 2006, Jul-27, Volume: 355, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Incidence; Platelet Aggregation Inhibitors; Ticlopidine

2006
Clopidogrel for the prevention of atherothrombotic events.
    The New England journal of medicine, 2006, Jul-27, Volume: 355, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2006
A pharmacoepidemiology study of the interaction between atorvastatin and clopidogrel after percutaneous coronary intervention.
    American heart journal, 2006, Volume: 152, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Heptanoic Acids; Humans; Logistic Models; Male; Middle Aged; Pharmacoepidemiology; Platelet Aggregation Inhibitors; Pyrroles; Quebec; Retrospective Studies; Stents; Ticlopidine

2006
End-stage renal disease and drug-eluting stents: one small step forward.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:9

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Coronary Restenosis; Humans; Infusion Pumps, Implantable; Kidney Failure, Chronic; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Prevalence; Renal Dialysis; Stents; Ticlopidine; Treatment Outcome

2006
[Cost-effectiveness of clopidogrel vs. aspirin treatment in high-risk acute coronary syndrome patients in Denmark].
    Ugeskrift for laeger, 2006, Aug-28, Volume: 168, Issue:35

    Topics: Acute Disease; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Cost-Benefit Analysis; Humans; Ischemia; Leg; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Syndrome; Ticlopidine

2006
Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement.
    Journal of the American College of Cardiology, 2006, Nov-07, Volume: 48, Issue:9

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Follow-Up Studies; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Treatment Outcome

2006
[The CHARISMA study: in search of the best antiplatelet strategy for cardiovascular prevention].
    Revue medicale de Liege, 2006, Volume: 61, Issue:9

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Ticlopidine

2006
Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:8

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Platelets; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Ticlopidine; Vasodilator Agents

2007
Comparison of drug-eluting stents with bare metal stents in unselected patients with acute myocardial infarction.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Jul-01, Volume: 70, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Cardiovascular Diseases; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Feasibility Studies; Female; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Metals; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Risk Assessment; Secondary Prevention; Sirolimus; Stents; Ticlopidine; Time Factors; Treatment Outcome

2007
Clopidogrel-statin interaction: myth or reality?
    Journal of the American College of Cardiology, 2007, Jul-24, Volume: 50, Issue:4

    Topics: Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Ticlopidine

2007
Aggressive antiplatelet strategies: time to reconsider?
    European heart journal, 2007, Volume: 28, Issue:18

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2007
Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness.
    Thrombosis research, 2008, Volume: 121, Issue:4

    Topics: Adult; Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Outpatients; Platelet Aggregation Inhibitors; Ticlopidine

2008
Clopidogrel resistance: a diagnostic challenge.
    International journal of cardiology, 2009, Jan-09, Volume: 131, Issue:2

    Topics: Cardiovascular Diseases; Clopidogrel; Diagnosis, Differential; Drug Resistance; Humans; Platelet Function Tests; Point-of-Care Systems; Ticlopidine

2009
An economic analysis of aspirin desensitization in aspirin-exacerbated respiratory disease.
    The Journal of allergy and clinical immunology, 2008, Volume: 121, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Markov Chains; Middle Aged; Models, Biological; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Respiration Disorders; Ticlopidine

2008
The "clopidogrel resistance" trap.
    The American journal of cardiology, 2007, Sep-15, Volume: 100, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Patient Compliance; Platelet Aggregation Inhibitors; Ticlopidine

2007
Platelet function testing and cardiovascular outcomes: steps forward in identifying the best predictive measure.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:4

    Topics: Adenosine Diphosphate; Cardiovascular Diseases; Clopidogrel; Flow Cytometry; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prognosis; Pyridines; ROC Curve; Sensitivity and Specificity; Ticlopidine; Treatment Outcome

2007
How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:2

    Topics: Adenosine Diphosphate; Aged; Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Drug Resistance; Feasibility Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Ticlopidine

2008
Evidence for prolonged prescribing of aspirin-clopidogrel combination in Scottish primary care.
    Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:4

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Population Surveillance; Primary Health Care; Retrospective Studies; Scotland; Ticlopidine

2008
What anti-thrombotic therapy is best with primary PCI for acute ST elevation myocardial infarction: how should the HORIZONS trial change current practice?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, May-01, Volume: 71, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Myocardial Infarction; Patient Selection; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Recombinant Proteins; Research Design; Stents; Thrombin; Thrombosis; Ticlopidine; Treatment Outcome

2008
Single antiplatelet therapy for patients with previous gastrointestinal bleeds.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:6

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Ticlopidine

2008
[Media and ethics: misunderstood requirement?].
    Journal des maladies vasculaires, 2008, Volume: 33, Issue:2

    Topics: Cardiovascular Diseases; Clopidogrel; Communications Media; Drug Industry; Drug Prescriptions; France; Platelet Aggregation Inhibitors; Ticlopidine

2008
[Evaluation of platelet aggregation in patients treated with ticlopidine].
    La Clinica terapeutica, 1984, Nov-15, Volume: 111, Issue:3

    Topics: Adult; Aged; Anticoagulants; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thiophenes; Thromboembolism; Ticlopidine

1984
Platelet activation in the cerebral circulation in different subtypes of ischemic stroke and Binswanger's disease.
    Stroke, 1995, Volume: 26, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cardiovascular Diseases; Cerebral Angiography; Cerebrovascular Circulation; Dementia, Vascular; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Thrombomodulin; Ticlopidine

1995
[Use of ticlopidine in primary care].
    Atencion primaria, 1996, Mar-31, Volume: 17, Issue:5

    Topics: Cardiovascular Diseases; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Primary Health Care; Ticlopidine

1996
Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Drug Resistance; Fatal Outcome; Female; Humans; Middle Aged; Neutropenia; Pancytopenia; Platelet Aggregation Inhibitors; Pneumonia; Respiratory Distress Syndrome; Ticlopidine

1997
Cardiovascular and Renal Advisory Panel of the FDA.
    Circulation, 1998, Mar-31, Volume: 97, Issue:12

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Kidney; Platelet Aggregation Inhibitors; Ticlopidine; United States; United States Food and Drug Administration

1998
[Cardiovascular secondary prevention. Convincing results with Clopidogrel].
    Zeitschrift fur Kardiologie, 1998, Volume: 87, Issue:7 Suppl Ub

    Topics: Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine

1998
[Prevention in the 21st century. Athero-thrombosis and ischemic events].
    Zeitschrift fur Kardiologie, 1998, Volume: 87, Issue:11 Suppl A

    Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Female; Forecasting; Humans; Male; Myocardial Ischemia; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine

1998
Antiplatelet drugs in cardiovascular prevention: take adverse effects and costs into account.
    Prescrire international, 2000, Volume: 9, Issue:47

    Topics: Aspirin; Cardiovascular Diseases; Cost-Benefit Analysis; Dipyridamole; Drug Costs; Flurbiprofen; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2000
Antiplatelet drugs in cardiovascular prevention: coronary events: acute phase and secondary prevention.
    Prescrire international, 2000, Volume: 9, Issue:47

    Topics: Angina, Unstable; Angioplasty; Anticoagulants; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Artery Bypass; Drug Therapy, Combination; Enoxaparin; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome

2000
Treatment of acute coronary syndromes.
    The New England journal of medicine, 2002, Jan-17, Volume: 346, Issue:3

    Topics: Acute Disease; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Meta-Analysis as Topic; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk; Ticlopidine

2002