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ticlopidine and Cardiac Death

ticlopidine has been researched along with Cardiac Death in 12 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"Aspirin resistance may increase the risk of major adverse cardiac events (MACE) more than threefold in patients with stable coronary artery disease (CAD)."9.12Clinical relevance of aspirin resistance in patients with stable coronary artery disease: a prospective follow-up study (PROSPECTAR). ( Mercanoglu, F; Meric, M; Nisanci, Y; Oflaz, H; Oncul, A; Onur, I; Ozcan, M; Pamukcu, B; Umman, B, 2007)
"To test the hypothesis that HRPR after clopidogrel loading is an independent prognostic marker of risk of long-term thrombotic events in patients with acute coronary syndromes (ACS) undergoing an invasive procedure and antithrombotic treatment adjusted according to the results of platelet function tests."7.77High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI. ( Abbate, R; Antoniucci, D; Buonamici, P; Gensini, GF; Giusti, B; Gori, AM; Marcucci, R; Migliorini, A; Parodi, G; Valenti, R, 2011)
" The elderly have an increased risk of (temporary) discontinuation of clopidogrel, which is associated with a higher risk of developing stent thrombosis (ST)."5.15Coronary stenting with the Genous™ Bio-Engineered R Stent™ in elderly patients. ( Beijk, M; Damman, P; de Winter, RJ; Iñiguez, A; Klomp, M; Ribeiro, EE; Silber, S; Sim, KH; Suryapranata, H; Tijssen, JG; Woudstra, P, 2011)
"Aspirin resistance may increase the risk of major adverse cardiac events (MACE) more than threefold in patients with stable coronary artery disease (CAD)."5.12Clinical relevance of aspirin resistance in patients with stable coronary artery disease: a prospective follow-up study (PROSPECTAR). ( Mercanoglu, F; Meric, M; Nisanci, Y; Oflaz, H; Oncul, A; Onur, I; Ozcan, M; Pamukcu, B; Umman, B, 2007)
" Meta-analyses evaluated effectiveness and adverse side effects for one-month administrations of aspirin plus cilostazol or aspirin plus ticlopidine therapy after coronary stenting."3.81Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting. ( Hashiguchi, M; Kishino, S; Mochizuki, M; Nakazawa, R; Ohno, K; Shiga, T, 2004)
"To test the hypothesis that HRPR after clopidogrel loading is an independent prognostic marker of risk of long-term thrombotic events in patients with acute coronary syndromes (ACS) undergoing an invasive procedure and antithrombotic treatment adjusted according to the results of platelet function tests."3.77High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI. ( Abbate, R; Antoniucci, D; Buonamici, P; Gensini, GF; Giusti, B; Gori, AM; Marcucci, R; Migliorini, A; Parodi, G; Valenti, R, 2011)
"The primary endpoint was a composite of cardiac death, non-fatal myocardial infarction and ischemic stroke at 6 months after PCI."2.76Inhibitory interaction between calcium channel blocker and clopidogrel. -Efficacy of cilostazol to overcome it-. ( Bae, JH; Bae, JW; Chae, IH; Cho, MC; Kim, HS; Lee, SP; Park, KW; Rha, SW; Suh, JW, 2011)
"CABG had similar rates of cardiac death compared with PCI group (HR=0."1.42Clinical outcomes of multiple chronic total occlusions in coronary arteries according to three therapeutic strategies: Bypass surgery, percutaneous intervention and medication. ( Choi, JH; Choi, SH; Gwon, HC; Hahn, JY; Jang, WJ; Kim, BS; Kim, WS; Lee, SH; Lee, YT; Song, YB; Yang, JH, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, BS1
Yang, JH1
Jang, WJ1
Song, YB1
Hahn, JY1
Choi, JH1
Kim, WS1
Lee, YT1
Gwon, HC1
Lee, SH1
Choi, SH1
Gori, AM2
Grifoni, E1
Valenti, R2
Giusti, B2
Paniccia, R1
Parodi, G2
Migliorini, A2
Antoniucci, D2
Abbate, R2
Gensini, GF2
Marcucci, R2
Massie, BM1
Collins, JF1
Ammon, SE1
Armstrong, PW1
Cleland, JG1
Ezekowitz, M1
Jafri, SM1
Krol, WF1
O'Connor, CM1
Schulman, KA1
Teo, K1
Warren, SR1
Kan, LP1
Chu, KM1
Lin, GM1
Lee, SP1
Bae, JW1
Park, KW1
Rha, SW1
Bae, JH1
Suh, JW1
Chae, IH1
Cho, MC1
Kim, HS1
Damman, P1
Iñiguez, A1
Klomp, M1
Beijk, M1
Woudstra, P1
Silber, S1
Ribeiro, EE1
Suryapranata, H1
Sim, KH1
Tijssen, JG1
de Winter, RJ1
Buonamici, P1
Angiolillo, DJ1
Gerson, LB1
McMahon, D1
Olkin, I1
Stave, C1
Rockson, SG1
Hashiguchi, M1
Ohno, K1
Nakazawa, R1
Kishino, S1
Mochizuki, M1
Shiga, T1
Pamukcu, B1
Oflaz, H1
Onur, I1
Oncul, A1
Ozcan, M1
Umman, B1
Mercanoglu, F1
Meric, M1
Nisanci, Y1
Unverdorben, M1
Degenhardt, R1
Wiemer, M1
Horstkotte, D1
Schneider, H1
Nienaber, C1
Bocksch, W1
Gross, M1
Boxberger, M1
Vallbracht, C1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CSP #442 - Warfarin and Antiplatelet Therapy Study in Patients With Congestive Heart Failure (WATCH)[NCT00007683]Phase 31,587 participants (Anticipated)Interventional1998-10-31Completed
REsponsiveness to CLOpidogrel and Stent-related Events in Acute Coronary. Reclose 2-ACS Registry[NCT01231035]1,789 participants (Actual)Observational2008-09-30Completed
EValuation of REsidual Platelet REactivity After Acute Coronary Syndrome in HIV-infected Patients. The EVERE2ST-HIV Study.[NCT02380391]260 participants (Actual)Observational2013-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ticlopidine and Cardiac Death

ArticleYear
Lack of significant interactions between clopidogrel and proton pump inhibitor therapy: meta-analysis of existing literature.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:5

    Topics: Cardiovascular Diseases; Clopidogrel; Death; Drug Interactions; Drug Therapy, Combination; Humans; O

2012
Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:3

    Topics: Administration, Oral; Aspirin; Cilostazol; Coronary Restenosis; Coronary Stenosis; Coronary Vessels;

2004

Trials

6 trials available for ticlopidine and Cardiac Death

ArticleYear
Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial.
    Circulation, 2009, Mar-31, Volume: 119, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chronic Disease; Clopidogrel; Death; Double-Blind Method; F

2009
Inhibitory interaction between calcium channel blocker and clopidogrel. -Efficacy of cilostazol to overcome it-.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:11

    Topics: Aged; Brain Ischemia; Calcium Channel Blockers; Cilostazol; Clopidogrel; Death; Drug Antagonism; Dru

2011
Coronary stenting with the Genous™ Bio-Engineered R Stent™ in elderly patients.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:11

    Topics: Age Factors; Aged; Angioplasty, Balloon, Coronary; Blood Vessel Prosthesis; Clopidogrel; Death; Fema

2011
Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:3

    Topics: Administration, Oral; Aspirin; Cilostazol; Coronary Restenosis; Coronary Stenosis; Coronary Vessels;

2004
Clinical relevance of aspirin resistance in patients with stable coronary artery disease: a prospective follow-up study (PROSPECTAR).
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:2

    Topics: Aged; Angina Pectoris; Aspirin; Clopidogrel; Coronary Artery Disease; Death; Drug Resistance; Female

2007
The paclitaxel-eluting Coroflex Please stent pilot study (PECOPS I) : the one-year clinical follow-up.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2007, Volume: 96, Issue:11

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Death; Drug-Eluting Stents; Female;

2007

Other Studies

5 other studies available for ticlopidine and Cardiac Death

ArticleYear
Clinical outcomes of multiple chronic total occlusions in coronary arteries according to three therapeutic strategies: Bypass surgery, percutaneous intervention and medication.
    International journal of cardiology, 2015, Oct-15, Volume: 197

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Bypass;

2015
High on-aspirin platelet reactivity predicts cardiac death in acute coronary syndrome patients undergoing PCI.
    European journal of internal medicine, 2016, Volume: 30

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Death; Drug

2016
Letter by Kan et al regarding Article, "randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart failure (WATCH) trial".
    Circulation, 2009, Nov-17, Volume: 120, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chronic Disease; Clopidogrel; Death; Double-Blind Method; F

2009
High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI.
    JAMA, 2011, Sep-21, Volume: 306, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Clopidogrel; Death; Fema

2011
High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI.
    JAMA, 2011, Sep-21, Volume: 306, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Clopidogrel; Death; Fema

2011
High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI.
    JAMA, 2011, Sep-21, Volume: 306, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Clopidogrel; Death; Fema

2011
High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI.
    JAMA, 2011, Sep-21, Volume: 306, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Clopidogrel; Death; Fema

2011
Applying platelet function testing in clinical practice: what are the unmet needs?
    JAMA, 2011, Sep-21, Volume: 306, Issue:11

    Topics: Acute Coronary Syndrome; Clopidogrel; Cohort Studies; Death; Humans; Myocardial Infarction; Platelet

2011