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ticlopidine and Cancer of Lung

ticlopidine has been researched along with Cancer of Lung in 16 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"To report a case of metastatic leiomyosarcoma, in which a patient developed chest pain accompanied by acute left bundle-branch block (LBBB) after gemcitabine infusion."3.75Gemcitabine-induced acute coronary syndrome: a case report. ( Benekli, M; Buyukberber, S; Coskun, U; Kaya, AO; Ozdemir, M; Ozturk, B; Sahin, G; Tacoy, G; Topal, S; Yaman, E; Yildiz, R, 2009)
"A new platelet aggregation inhibitor compound, 5-(2-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-C]pyridine hydrochloride (ticlopidine), was examined for its inhibitory effects on blood-borne metastasis using three different rodent tumors (B16 melanoma, Lewis lung carcinoma, and rat ascites hepatoma, AH130)."3.66Effects of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (Ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis. ( Ishihara, M; Kinjo, M; Kohga, S; Ogawa, H; Tanaka, K; Tanaka, N, 1981)
"However, the number and size of lung metastases were reduced in treated animals when examined at the time of sacrifice."1.31Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model. ( Bergerat, JP; Cazenave, JP; Céraline, J; Chenard, MP; Deplanque, G; Klein-Soyer, C; Mah-Becherel, MC, 2002)
" Nineteen out of them were treated with warfarin plus ticlopidine at a dosage enough to prolong the thrombo-test time to approximately 20% of normal value."1.27[Abnormalities of blood coagulation and effect of anticoagulant therapy in postoperative patients with lung cancer]. ( Inoue, H; Kawada, S; Koide, S; Ogawa, J; Shohtsu, A; Tsurumi, T, 1986)
"Pulmonary metastases with CT26 cells could be inhibited by induction of thrombocytopenia, and reconstituted by infusion of either murine or human platelets."1.27Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. ( Ambrogio, C; Coller, BS; Karpatkin, S; Pearlstein, E, 1988)
"Ticlopidine was administered orally at the selected dose (200 mg/kg/day), to the rodents using different dose schedules and the inhibitory effects on spontaneous lung metastases of the Lewis lung carcinoma were studied."1.27Effects of ticlopidine on metastasis production in mice bearing Lewis lung carcinoma. ( Carretero, F; de Castellarnau, C; Fabra, A; Martínez, E; Rutllant, ML; Sancho, MJ, 1987)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atay, SM1
Correa, AM1
Hofstetter, WL1
Mehran, RJ1
Rice, DC1
Roth, JA1
Sepesi, B1
Swisher, SG1
Vaporciyan, AA1
Walsh, G1
Antonoff, MB1
Ochmański, W1
Ozturk, B1
Tacoy, G1
Coskun, U1
Yaman, E1
Sahin, G1
Buyukberber, S1
Yildiz, R1
Kaya, AO1
Topal, S1
Ozdemir, M1
Benekli, M1
Stather, DR1
MacEachern, P1
Chee, A1
Tremblay, A1
Controtto, F1
Scacciatella, P1
Cristofori, R1
Grasso, C1
D'Amico, M1
Pennone, M1
Marra, S1
Serebruany, VL1
Dinicolantonio, JJ1
Can, MM1
Goto, S1
Mychaskiw, G1
Vaughn, C1
Maslow, A1
Bert, A1
Ng, T1
Bando, H1
Yamashita, T1
Tsubura, E1
Kohga, S1
Kinjo, M1
Tanaka, K1
Ogawa, H1
Ishihara, M1
Tanaka, N1
Mah-Becherel, MC1
Céraline, J1
Deplanque, G1
Chenard, MP1
Bergerat, JP1
Cazenave, JP1
Klein-Soyer, C1
Ogawa, J3
Tsurumi, T2
Inoue, H5
Koide, S3
Kawada, S3
Shohtsu, A3
Karpatkin, S1
Pearlstein, E1
Ambrogio, C1
Coller, BS1
Fabra, A1
de Castellarnau, C1
Carretero, F1
Martínez, E1
Sancho, MJ1
Rutllant, ML1

Trials

1 trial available for ticlopidine and Cancer of Lung

ArticleYear
[Influence of antiplatelet drugs (AD) on the efectiveness of combined therapy in patients with small cell lung cancer. Part I. Influence of AD on the haemostatic system].
    Przeglad lekarski, 2008, Volume: 65, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Blood Coagulation; Carcinoma,

2008

Other Studies

15 other studies available for ticlopidine and Cancer of Lung

ArticleYear
Perioperative Outcomes of Patients Undergoing Lobectomy on Clopidogrel.
    The Annals of thoracic surgery, 2017, Volume: 104, Issue:6

    Topics: Aged; Aged, 80 and over; Clopidogrel; Databases, Factual; Drug Administration Schedule; Female; Huma

2017
Gemcitabine-induced acute coronary syndrome: a case report.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2009, Volume: 18, Issue:1

    Topics: Antimetabolites, Antineoplastic; Aspirin; Bundle-Branch Block; Clopidogrel; Coronary Artery Disease;

2009
Safety of endobronchial ultrasound-guided transbronchial needle aspiration for patients taking clopidogrel: a report of 12 consecutive cases.
    Respiration; international review of thoracic diseases, 2012, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Biopsy, Fine-Needle; Bronchoscopy; Clopidogrel; Endosonography; Female; Fol

2012
Double interruption of antiplatelet therapy and tirofiban "bridging" for lung cancer resection.
    Minerva medica, 2012, Volume: 103, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Biopsy, Needle; Clopidogrel; Coronary Restenosis; Drug Administration

2012
Unclassified pleomorphic and spindle cell pulmonary neoplasm with brain metastases after prasugrel.
    Cardiology, 2013, Volume: 124, Issue:2

    Topics: Aged; Aspirin; Brain Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Clopidogrel; Colonic

2013
Massive hemorrhage during radiofrequency ablation of a pulmonary neoplasm.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:4

    Topics: Catheter Ablation; Clopidogrel; Hemorrhage; Humans; Intraoperative Complications; Lung Neoplasms; Pl

2003
Case 6-2005 thoracotomy after myocardial infarction and intracoronary stenting: a balance between myocardial recovery and procedural risk.
    Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:6

    Topics: Clopidogrel; Coronary Disease; Exercise Test; Female; Humans; Lung; Lung Neoplasms; Middle Aged; Myo

2005
Effects of antiplatelet agents on pulmonary metastases.
    Gan, 1984, Volume: 75, Issue:3

    Topics: Adenosine Diphosphate; Animals; Depression, Chemical; Diltiazem; Dipyridamole; Dose-Response Relatio

1984
Effects of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (Ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Animals; Cell Line; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Mic

1981
Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model.
    British journal of cancer, 2002, Mar-04, Volume: 86, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Aorta; Cell Division; Clopidogrel; Disease Models, Animal; Foot; G

2002
[Abnormalities of blood coagulation and effect of anticoagulant therapy in postoperative patients with lung cancer].
    Nihon Geka Gakkai zasshi, 1986, Volume: 87, Issue:6

    Topics: Adult; Aged; Anticoagulants; beta-Thromboglobulin; Blood Coagulation Disorders; Female; Humans; Lung

1986
Interactions between UFT and anticoagulants in lung cancer patients.
    The Japanese journal of surgery, 1988, Volume: 18, Issue:3

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Drug Interactions; Drug Therap

1988
[Experimental and clinical study of interactions between fluorinated pyrimidine derivatives and anticoagulants].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8

    Topics: Animals; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug

1988
Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Humans; Immunologic Techniques; Lung Neop

1988
Effects of ticlopidine on metastasis production in mice bearing Lewis lung carcinoma.
    Invasion & metastasis, 1987, Volume: 7, Issue:1

    Topics: Animals; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Platelet Aggregation; Ticlop

1987