ticlopidine has been researched along with Brain Infarction in 8 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two Phase III studies comparing the safety and efficacy of clopidogrel with ticlopidine as antiplatelet agents for the secondary prevention of vascular events in patients with prior stroke were performed in Japan." | 9.14 | The safety and efficacy of clopidogrel versus ticlopidine in Japanese stroke patients: combined results of two Phase III, multicenter, randomized clinical trials. ( Fukuuchi, Y; Uchiyama, S; Yamaguchi, T, 2009) |
| "Two Phase III studies comparing the safety and efficacy of clopidogrel with ticlopidine as antiplatelet agents for the secondary prevention of vascular events in patients with prior stroke were performed in Japan." | 5.14 | The safety and efficacy of clopidogrel versus ticlopidine in Japanese stroke patients: combined results of two Phase III, multicenter, randomized clinical trials. ( Fukuuchi, Y; Uchiyama, S; Yamaguchi, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hassan, H | 1 |
| Ehsanula, H | 1 |
| Pattanshetti, M | 1 |
| Pedersen, OH | 1 |
| Larsen, ML | 1 |
| Kristensen, SD | 1 |
| Hvas, AM | 1 |
| Grove, EL | 1 |
| Pan, Y | 1 |
| Meng, X | 1 |
| Jing, J | 1 |
| Li, H | 1 |
| Zhao, X | 1 |
| Liu, L | 1 |
| Wang, D | 1 |
| Johnston, SC | 1 |
| Wang, Y | 2 |
| Uchiyama, S | 1 |
| Fukuuchi, Y | 1 |
| Yamaguchi, T | 1 |
| Weise, J | 1 |
| Reinhöfer, M | 1 |
| Witte, OW | 1 |
| Mayer, TE | 1 |
| Larroche, C | 1 |
| Chadenat, ML | 1 |
| Chaunu, MP | 1 |
| Abad, S | 1 |
| Casassus, P | 1 |
| Dhôte, R | 1 |
| Las Herasa, G | 1 |
| Robles, B | 1 |
| Callén, A | 1 |
| Beneitez, D | 1 |
| Nielsen, AA | 1 |
| Veien, KT | 1 |
| Jørgensen, LG | 1 |
| Buck, TC | 1 |
| Brandslund, I | 1 |
| Christensen, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized,Double-blind Trial Comparing the Effects of a 3-month Clopidogrel Regimen,Combined With ASA During the First 21days,Versus ASA Alone for the Acute Treatment of TIA or Minor Stroke[NCT00979589] | Phase 3 | 5,100 participants (Actual) | Interventional | 2009-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ticlopidine and Brain Infarction
| Article | Year |
|---|---|
Association of multiple infarctions and ICAS with outcomes of minor stroke and TIA.
Topics: Aged; Aspirin; Brain; Brain Infarction; Brain Ischemia; Clopidogrel; Female; Humans; Image Processin | 2017 |
The safety and efficacy of clopidogrel versus ticlopidine in Japanese stroke patients: combined results of two Phase III, multicenter, randomized clinical trials.
Topics: Aged; Brain Infarction; Clopidogrel; Double-Blind Method; Female; Follow-Up Studies; Humans; Inciden | 2009 |
6 other studies available for ticlopidine and Brain Infarction
| Article | Year |
|---|---|
Stroke of the inferiomedial temporal lobe causing word agnosia.
Topics: Aged; Agnosia; Brain Infarction; Clopidogrel; Humans; Intelligence Tests; Magnetic Resonance Imaging | 2017 |
Recurrent Cardiovascular Events Despite Antiplatelet Therapy in a Patient with Polycythemia Vera and Accelerated Platelet Turnover.
Topics: Adenosine; Brain Infarction; Clopidogrel; Drug Therapy, Combination; Humans; Male; Middle Aged; Myoc | 2017 |
Early stent thrombosis with progressive brainstem infarction in a clopidogrel non-responder.
Topics: Aged; Brain Infarction; Brain Ischemia; Clopidogrel; Disease Progression; Humans; Magnetic Resonance | 2010 |
[Strokes associated with cervical artery dissection, and systemic mastocytosis: an unfortuitous association? A report of two cases].
Topics: Aspirin; Brain Infarction; Carotid Artery, Internal, Dissection; Carotid Stenosis; Clopidogrel; Fibr | 2005 |
[Clopidrogrel and deficiency of glucose 6 phosphate dehydrogenase].
Topics: Aged; Brain Infarction; Clopidogrel; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase | 2006 |
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin; | 2008 |