ticlopidine has been researched along with Brain Edema in 5 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute cerebral ischemia was produced in rats by injection of arachidonic acid (AA) into the internal carotid artery." | 7.68 | Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. ( Karasawa, A; Kubo, K; Sano, J; Shirakura, S, 1992) |
| "Acute cerebral ischemia was produced in rats by injection of arachidonic acid (AA) into the internal carotid artery." | 3.68 | Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. ( Karasawa, A; Kubo, K; Sano, J; Shirakura, S, 1992) |
| "Cerebral ischemia was mechanically induced by 2-hour occlusion of the left middle cerebral artery (MCA) using an intraluminal filament followed by 24-hour reperfusion." | 1.33 | Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. ( Hong, KW; Lee, JH; Lee, WS; Park, SY, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Georgiadis, D | 1 |
| Michel, P | 1 |
| Bogousslavsky, J | 1 |
| Baumgartner, RW | 1 |
| Lee, JH | 1 |
| Park, SY | 1 |
| Lee, WS | 1 |
| Hong, KW | 1 |
| Imura, Y | 1 |
| Kiyota, Y | 1 |
| Nagai, Y | 1 |
| Nishikawa, K | 1 |
| Terashita, Z | 1 |
| Bruno, A | 1 |
| Shirakura, S | 1 |
| Sano, J | 1 |
| Karasawa, A | 1 |
| Kubo, K | 1 |
1 review available for ticlopidine and Brain Edema
| Article | Year |
|---|---|
[Treatment of acute stroke -- an overview].
Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Brain Edema; Case-Control Studies; Cereb | 2003 |
4 other studies available for ticlopidine and Brain Edema
| Article | Year |
|---|---|
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.
Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Ede | 2005 |
Beneficial effect of CV-4151 (Isbogrel), a thromboxane A2 synthase inhibitor, in a rat middle cerebral artery thrombosis model.
Topics: Animals; Aspirin; Brain Chemistry; Brain Edema; Cerebral Arteries; Cerebral Infarction; Drug Evaluat | 1995 |
Ischemic stroke, Part 2: Optimal treatment and prevention.
Topics: Aged; Aspirin; Brain Edema; Brain Ischemia; Cerebral Infarction; Heparin; Humans; Recurrence; Risk F | 1993 |
Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats.
Topics: Animals; Arachidonic Acid; Benzoquinones; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Calcium | 1992 |