Page last updated: 2024-11-05

ticlopidine and Blood Poisoning

ticlopidine has been researched along with Blood Poisoning in 11 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"We report a case of ticlopidine-induced profound neutropenia early in the course of therapy, which was manifest as a febrile systemic illness mimicking sepsis."8.80Ticlopidine-induced neutropenia mimicking sepsis early after intracoronary stent placement. ( Lenihan, DJ; Lewis, P; Ochoa, AB; Wolfe, M, 1998)
" We analysed adverse events (AEs) consistent with either pulmonary infection or sepsis, and subsequent mortality, in 18,421 PLATO patients treated with ticagrelor or clopidogrel."6.79Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study. ( Åsenblad, N; Becker, RC; Cannon, CP; Held, C; Husted, SE; James, SK; Siegbahn, A; Steg, PG; Storey, RF; Varenhorst, C; Wallentin, L; Ycas, J, 2014)
"We report a case of ticlopidine-induced profound neutropenia early in the course of therapy, which was manifest as a febrile systemic illness mimicking sepsis."4.80Ticlopidine-induced neutropenia mimicking sepsis early after intracoronary stent placement. ( Lenihan, DJ; Lewis, P; Ochoa, AB; Wolfe, M, 1998)
"Using a mouse model of intra-abdominal sepsis and acute lung injury, we investigated the role of the P2Y12 receptor in neutrophil migration and lung inflammation in P2Y12 null mice and in mice pretreated with the P2Y12 antagonist clopidogrel."3.83P2Y12 Receptor Modulates Sepsis-Induced Inflammation. ( Kilpatrick, LE; Kunapuli, SP; Liverani, E; Rico, MC; Tsygankov, AY, 2016)
"Analyzing medical records of 979 patients with severe sepsis or septic shock provided some evidence that the use of low-dose aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) was associated with decreased hospital mortality."3.79Benefit of low-dose aspirin and non-steroidal anti-inflammatory drugs in septic patients. ( Boettel, J; Lösche, W; Otto, GP; Sossdorf, M; Winning, J, 2013)
" We analysed adverse events (AEs) consistent with either pulmonary infection or sepsis, and subsequent mortality, in 18,421 PLATO patients treated with ticagrelor or clopidogrel."2.79Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study. ( Åsenblad, N; Becker, RC; Cannon, CP; Held, C; Husted, SE; James, SK; Siegbahn, A; Steg, PG; Storey, RF; Varenhorst, C; Wallentin, L; Ycas, J, 2014)
"Ticlopidine-induced aplastic anemia (TIAA) is considered very uncommon."2.41Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases. ( Fragopanagou, E; Galani, A; Giannakoulas, N; Kouraklis-Symeonidis, A; Matsouka, P; Seimeni, U; Symeonidis, A; Tiniakou, M; Zoumbos, N, 2002)
"Atherosclerosis is considered as a moderate systemic inflammation and we hypothesise that this chronic condition could have an impact on the outcome in sepsis."1.39Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock. ( Boettel, J; Breuel, H; Kabisch, B; Lösche, W; Otto, GP; Sossdorf, M; Winning, J, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Storey, RF1
James, SK1
Siegbahn, A1
Varenhorst, C1
Held, C1
Ycas, J1
Husted, SE1
Cannon, CP1
Becker, RC1
Steg, PG1
Åsenblad, N1
Wallentin, L1
Iskandar, MZ1
Chong, V1
Hutcheon, S1
Serebruany, VL1
Liverani, E1
Rico, MC1
Tsygankov, AY1
Kilpatrick, LE1
Kunapuli, SP1
Alosh, M1
Huque, MF1
Bretz, F1
D'Agostino, RB1
Seidel, M1
Winning, J3
Claus, RA1
Bauer, M1
Lösche, W3
Otto, GP2
Sossdorf, M2
Boettel, J2
Kabisch, B1
Breuel, H1
Symeonidis, A1
Kouraklis-Symeonidis, A1
Seimeni, U1
Galani, A1
Giannakoulas, N1
Fragopanagou, E1
Tiniakou, M1
Matsouka, P1
Zoumbos, N1
Ochoa, AB1
Wolfe, M1
Lewis, P1
Lenihan, DJ1
Korkmaz, ME1
Cekin, AH1

Reviews

2 reviews available for ticlopidine and Blood Poisoning

ArticleYear
Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases.
    American journal of hematology, 2002, Volume: 71, Issue:1

    Topics: Age Distribution; Aged; Aged, 80 and over; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents;

2002
Ticlopidine-induced neutropenia mimicking sepsis early after intracoronary stent placement.
    Clinical cardiology, 1998, Volume: 21, Issue:4

    Topics: Coronary Angiography; Coronary Disease; Diagnosis, Differential; Female; Follow-Up Studies; Humans;

1998

Trials

1 trial available for ticlopidine and Blood Poisoning

ArticleYear
Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study.
    Platelets, 2014, Volume: 25, Issue:7

    Topics: Adenosine; Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet A

2014

Other Studies

8 other studies available for ticlopidine and Blood Poisoning

ArticleYear
Acute spinal cord compression: a rare complication of dual antiplatelet therapy.
    BMJ case reports, 2015, Jul-22, Volume: 2015

    Topics: Acute Disease; Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Fatal Outcome; Female; Hematom

2015
Ticagrelor shift from PLATO to PEGASUS: Vanished mortality benefit, excess cancer deaths, massive discontinuations, and overshooting target events.
    International journal of cardiology, 2015, Dec-15, Volume: 201

    Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Follow-Up Studies; Hemorrhage; Humans; Mor

2015
P2Y12 Receptor Modulates Sepsis-Induced Inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:5

    Topics: Acute Lung Injury; Animals; Blood Platelets; Clopidogrel; Cytokines; Genetic Predisposition to Disea

2016
Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials.
    Statistics in medicine, 2017, 04-15, Volume: 36, Issue:8

    Topics: Aspirin; Clopidogrel; Data Interpretation, Statistical; Humans; Models, Statistical; Myocardial Infa

2017
Beneficial effect of clopidogrel in a mouse model of polymicrobial sepsis.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:6

    Topics: Animals; Clopidogrel; Mice; Platelet Aggregation Inhibitors; Sepsis; Ticlopidine

2009
Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock.
    Platelets, 2013, Volume: 24, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Blood Coagulation; Clopidog

2013
Benefit of low-dose aspirin and non-steroidal anti-inflammatory drugs in septic patients.
    Critical care (London, England), 2013, Jan-08, Volume: 17, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Dose-Response Relationship, Dru

2013
Bone marrow suppression and klebsiella pneumonia septicemia due to ticlopidine and successful treatment with filgrastim; a case report.
    International journal of cardiology, 1998, Oct-30, Volume: 66, Issue:3

    Topics: Biopsy, Needle; Bone Marrow; Female; Filgrastim; Follow-Up Studies; Granulocyte Colony-Stimulating F

1998