Compounds > ticlopidine
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ticlopidine and Bile Duct Obstruction

ticlopidine has been researched along with Bile Duct Obstruction in 38 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"We report a case of ticlopidine-induced prolonged cholestasis in a 60-year-old man with no previous hepatobiliary disease who presented with sudden right upper abdominal pain, jaundice and pruritus three months after starting ticlopidine therapy."7.70Ticlopidine-induced prolonged cholestasis: a case report. ( Amaro, P; Baranda, J; Cipriano, A; Donato, A; Freitas, D; Maçôas, F; Martins, I; Ministro, P; Nunes, A; Pimenta, I; Rosa, A, 1999)
"The case of a 56-years-old male with cholestasis associated with ticlopidine is presented."7.69[Cholestasis associated with ticlopidine]. ( Avagnina, A; Díaz Fuenzalida, A; Findor, JA; Laudano, O; Valdés Socín, H, 1997)
"We report a case of ticlopidine-induced prolonged cholestasis in a 60-year-old man with no previous hepatobiliary disease who presented with sudden right upper abdominal pain, jaundice and pruritus three months after starting ticlopidine therapy."3.70Ticlopidine-induced prolonged cholestasis: a case report. ( Amaro, P; Baranda, J; Cipriano, A; Donato, A; Freitas, D; Maçôas, F; Martins, I; Ministro, P; Nunes, A; Pimenta, I; Rosa, A, 1999)
"The case of a 56-years-old male with cholestasis associated with ticlopidine is presented."3.69[Cholestasis associated with ticlopidine]. ( Avagnina, A; Díaz Fuenzalida, A; Findor, JA; Laudano, O; Valdés Socín, H, 1997)
"Six years later after a left cerebral transient ischemic attack aspirin was replaced by ticlopidine."2.41[Cholestatic hepatitis as a rare side effect of therapy with ticlopidine]. ( Auer, J; Berent, R; Haidenthaler, A; Hinterholzer, G; Höbling, W; Knoflach, P, 2000)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's21 (55.26)18.2507
2000's12 (31.58)29.6817
2010's3 (7.89)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Dawson, S1
Stahl, S1
Paul, N1
Barber, J1
Kenna, JG1
Gabbi, C1
Bertolotti, M1
Joshi, N1
Kopec, AK1
Ray, JL1
Luyendyk, JP1
Yoshikado, T1
Takada, T1
Yamamoto, H1
Tan, JK1
Ito, K1
Santa, T1
Suzuki, H1
Skurnik, YD1
Tcherniak, A1
Edlan, K1
Sthoeger, Z1
Lee, JY1
Park, EB1
Ahn, JH1
Suh, SJ1
Jung, YK1
Kim, JH1
Shin, BK1
Yang, JH1
Yeon, JE1
Byun, KS1
Eugene, C1
Lefebvre, JF1
Gury, B1
Quevauvilliers, J1
Miras Parra, FJ1
Gómez Jiménez, FJ1
García Contreras, T1
Valverde Romera, M1
Naschitz, JE1
Khamessi, R1
Elias, N1
Yeshurun, D1
Cassidy, LJ1
Schuster, BG1
Halparin, LS1
Weber, E1
Donckier, J1
Yoder, JD1
Algozzine, GJ1
Hill, GW1
Nurhussein, MA1
Greany, JJ1
Hess, DA1
Mahoney, CD1
López, P1
Castiella, A1
Bujanda, L1
Arenas, JI1
Pascual, S1
Sarrión, JV1
Jarque, I1
Argüello, L1
Berenguer, J1
Díaz Fuenzalida, A1
Valdés Socín, H1
Laudano, O1
Avagnina, A1
Findor, JA1
Bruguera, M1
Guzzini, F1
Banfi, L1
Gomitoni, A1
Marchegiani, C1
Novati, P1
Mesina, M1
Frigerio, B1
Yim, HB1
Lieu, PK1
Choo, PW1
San Juan Portugal, F1
Jiménez Saez, J1
Naya Manchado, J1
Fuentes Solsona, F1
Wegmann, C1
Münzenmaier, R1
Dormann, AJ1
Huchzermeyer, H1
Iqbal, M1
Goenka, P1
Young, MF1
Thomas, E1
Borthwick, TR1
Amaro, P1
Nunes, A1
Maçôas, F1
Ministro, P1
Baranda, J1
Cipriano, A1
Martins, I1
Rosa, A1
Pimenta, I1
Donato, A1
Freitas, D1
Torrano Larrión, F1
Kubin, CJ1
Sherman, O1
Hussain, KB1
Feinman, L1
Meyer, MI1
Kuhn, M1
Bühler, H1
Bertschinger, P1
Berent, R1
Hinterholzer, G1
Höbling, W1
Auer, J1
Haidenthaler, A1
Knoflach, P1
Wu, MS1
Chan, P1
Lien, GS1
Cheng, YS1
Pan, S1
Wengrower, D1
de la Iglesia Martínez, F1
Trinidad Sanjosé, JC1
Nicolás Miguel, R1
Ramos Polledo, V1
Pellicer Vázquez, C1
Diz-Lois Martínez, F1
Tsai, MH1
Tsai, SL1
Chen, TC1
Liaw, YF1
García Ortega, P1
José Navarro, J1
Carvajal, A1
García del Pozo, J1
Willens, HJ1
López López, M1
Martín López, A1
Moreno Feliu, R1
Alberti, L1
Alberti-Flor, JJ1
Adams, L1
Jeffrey, GP1
Deboer, B1
Garas, G1
Mammarella, A1
Paoletti, V1
Moroni, C1
Cassone, R1

Reviews

3 reviews available for ticlopidine and Bile Duct Obstruction

ArticleYear
Ticlopidine induced cholestatic jaundice.
    Singapore medical journal, 1997, Volume: 38, Issue:3

    Topics: Aged; Cerebrovascular Disorders; Cholestasis; Fatal Outcome; Female; Humans; Platelet Aggregation In

1997
Ticlopidine-induced cholestatic hepatitis: report of three cases and review of the literature.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:10

    Topics: Aged; Aged, 80 and over; Cerebrovascular Disorders; Chemical and Drug Induced Liver Injury; Cholesta

1998
[Cholestatic hepatitis as a rare side effect of therapy with ticlopidine].
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:7

    Topics: Aged; Atrial Fibrillation; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Cholestasis; Chro

2000

Other Studies

35 other studies available for ticlopidine and Bile Duct Obstruction

ArticleYear
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
Reduced multidrug resistance-associated protein 2 in ticlopidine-induced cholestatic liver injury.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020, Volume: 52, Issue:2

    Topics: Aged, 80 and over; Biomarkers; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans;

2020
Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease.
    Toxicology, 2016, 07-15, Volume: 365

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Clopidogrel;

2016
Ticlopidine, a cholestatic liver injury-inducible drug, causes dysfunction of bile formation via diminished biliary secretion of phospholipids: involvement of biliary-excreted glutathione-conjugated ticlopidine metabolites.
    Molecular pharmacology, 2013, Volume: 83, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Bil

2013
Ticlopidine-induced cholestatic hepatitis.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:3

    Topics: Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Platelet

2003
[A case of ticlopidine induced acute cholestatic hepatitis and pure red cell aplasia].
    The Korean journal of hepatology, 2008, Volume: 14, Issue:1

    Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Liver Function T

2008
[Cholestatic hepatitis. Presumptive role of ticlopidine].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Nov-17, Volume: 59, Issue:42

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Thiophenes; Ticlopidine

1983
[Ticlopidine-induced cholestatic hepatitis].
    Revista espanola de enfermedades digestivas, 1995, Volume: 87, Issue:5

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Thrombophlebitis; Ticlopi

1995
Ticlopidine-induced prolonged cholestasis.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:4

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Female; Humans; Tic

1995
Probable ticlopidine-induced cholestatic hepatitis.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:1

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Ticlopidine

1995
[Cholestatic jaundice due to ticlopidine: a new case].
    Acta clinica Belgica, 1994, Volume: 49, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Coronary Disease; Diagnosis, Differential; Huma

1994
More ticlopidine-induced cholestatic jaundice.
    American journal of hospital pharmacy, 1994, Jul-15, Volume: 51, Issue:14

    Topics: Aged; Aged, 80 and over; Cholestasis; Female; Humans; Liver Function Tests; Ticlopidine

1994
Ticlopidine-induced prolonged cholestasis.
    Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:12

    Topics: Aged; Aged, 80 and over; Cholestasis; Humans; Ischemic Attack, Transient; Male; Ticlopidine

1993
Ticlopidine-induced cholestatic jaundice.
    Clinical pharmacy, 1993, Volume: 12, Issue:6

    Topics: Aged; Cholestasis; Female; Humans; Ticlopidine

1993
[Ticlopidine-induced cholestatic hepatitis. A case report].
    Revista espanola de enfermedades digestivas, 1995, Volume: 87, Issue:10

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Fibrinolytic Agents; Humans; Male; Ticlop

1995
[Cholestatic hepatitis and anemia induced by ticlopidine].
    Gastroenterologia y hepatologia, 1996, Volume: 19, Issue:4

    Topics: Acute Disease; Aged; Anemia; Cerebrovascular Disorders; Chemical and Drug Induced Liver Injury; Chol

1996
[Cholestasis associated with ticlopidine].
    Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:3

    Topics: Biopsy; Cholestasis; Humans; Liver; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine;

1997
[Cholestatic hepatitis associated with ticlopidine].
    Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:3

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Middle Aged; Platelet Agg

1997
[2 cases of acute cholestasis caused by ticlopidine].
    Recenti progressi in medicina, 1997, Volume: 88, Issue:3

    Topics: Acute Disease; Adult; Aged; Biopsy; Cholestasis; Female; Humans; Liver; Platelet Aggregation Inhibit

1997
[Cholestatic hepatitis due to ticlopidine: a report of a new case].
    Anales de medicina interna (Madrid, Spain : 1984), 1997, Volume: 14, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Middle Aged; Platelet Aggregation

1997
[Ticlopidine-induced acute cholestatic hepatitis].
    Deutsche medizinische Wochenschrift (1946), 1998, Feb-06, Volume: 123, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cerebell

1998
Ticlopidine-induced prolonged cholestasis: a case report.
    European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:6

    Topics: Cholestasis; Humans; Liver Function Tests; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlo

1999
[Cholestatic hepatitis from ticlopidine].
    Atencion primaria, 1999, Jun-30, Volume: 24, Issue:2

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Fibrinolytic Agents; Humans; Ticl

1999
Delayed-onset ticlopidine-induced cholestatic jaundice.
    Pharmacotherapy, 1999, Volume: 19, Issue:8

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Liver Function Tests; Male; Plate

1999
[Ticlopidine-induced cholestasis].
    Schweizerische medizinische Wochenschrift, 1999, Oct-02, Volume: 129, Issue:39

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestas

1999
Ticlopidine-induced severe cholestatic hepatitis.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 2000, Volume: 63, Issue:8

    Topics: Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Platel

2000
Possible ticlopidine-induced cholestatic jaundice.
    American family physician, 2000, Sep-15, Volume: 62, Issue:6

    Topics: Aged; Cholestasis; Coronary Disease; Female; Follow-Up Studies; Humans; Liver Function Tests; Male;

2000
[Ticlopidine induced cholestatic hepatitis].
    Anales de medicina interna (Madrid, Spain : 1984), 2000, Volume: 17, Issue:9

    Topics: Aged; Cholestasis; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine

2000
Ticlopidine-induced cholestatic hepatitis with anti-nuclear antibody in serum.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:11

    Topics: Antibodies, Antinuclear; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Liver; Male; M

2000
[Cholestatic hepatitis by ticlopidin].
    Medicina clinica, 2001, Jan-27, Volume: 116, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Middle Aged; Platelet Aggregation

2001
Clopidogrel-induced mixed hepatocellular and cholestatic liver injury.
    American journal of therapeutics, 2000, Volume: 7, Issue:5

    Topics: Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Hepatocytes; H

2000
[Ticlopidine, cholestasis and hepatic nodules].
    Medicina clinica, 2001, Oct-20, Volume: 117, Issue:12

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Middle Aged; Ticlopidine

2001
Ticlopidine-induced cholestatic hepatitis successfully treated with corticosteroids.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:4

    Topics: Aged; Cholestasis; Female; Glucocorticoids; Hepatitis; Humans; Methylprednisolone; Platelet Aggregat

2002
Ticlopidine-associated cholestatic hepatitis.
    Internal medicine journal, 2002, Volume: 32, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Diagnosis, Differential; Humans; Male; Middle A

2002
[Ticlopidine-induced cholestatic jaundice].
    La Clinica terapeutica, 1991, Jul-15, Volume: 138, Issue:1

    Topics: Aged; Bilirubin; Cholestasis; Humans; Male; Ticlopidine

1991