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ticlopidine and Arterial Diseases, Carotid

ticlopidine has been researched along with Arterial Diseases, Carotid in 32 studies

Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.

Research Excerpts

ExcerptRelevanceReference
"End-pouch ECA aneurysms were created in adult rats and were then embedded with either platinum or HydroCoils."7.83Aspirin and Clopidogrel Inhibit Aneurysm Healing after HydroCoil Implantation in External Carotid Artery Aneurysm Model. ( Chaudhary, N; Gemmete, JJ; Li, P; Pandey, AS; Thompson, BG; Xi, G; Zhang, C, 2016)
"The objective of this study was to compare nonresponders (NR) and responders (R) to clopidogrel with respect to presence of microvascular and macrovascular pathology in a cohort of patients with recent minor ischemic stroke (IS) or transient ischemic attack (TIA)."7.81Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease. ( Gigante, B; Höeg Dembrower, K; Jörneskog, G; Laska, AC; Laurencikas, E; Lundström, A; von Arbin, M; Wallén, H, 2015)
"9 years) with ischemic stroke or carotid artery stenting who received clopidogrel (75 mg) for >7 days at our hospital between October 2009 and March 2010."7.77Clopidogrel resistance and the effect of combination cilostazol in patients with ischemic stroke or carotid artery stenting using the VerifyNow P2Y12 Assay. ( Deguchi, I; Dembo, T; Fukuoka, T; Horiuchi, Y; Kato, Y; Maruyama, H; Nagoya, H; Takeda, H; Tanahashi, N, 2011)
"Ferric chloride has been widely used to induce arterial thrombosis in a variety of species."5.33An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. ( Wang, X; Xu, L, 2005)
"The purpose of this review is to update our current knowledge and understanding of the pharmacogenetic basis for poor clopidogrel responsiveness in patients undergoing CAS and endovascular interventions as well as to explore usefulness of genotyping to reduce the rate of procedure-related thrombosis that results in ischemic complications."4.95Potential Usefulness of Clopidogrel Pharmacogenetics in Cerebral Endovascular Procedures and Carotid Artery Stenting. ( Duconge, J; Hernandez-Suarez, DF, 2017)
" Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in addition to regular 75 mg aspirin which virtually abolished post-operative thromboembolic stroke and may also have contributed towards a decline in stroke/death following major cardiac events; and (iii) the provision of written guidance for managing post-CEA hypertension which was associated with virtual abolition of intracranial haemorrhage and stroke as a result of hyperperfusion syndrome."4.89Closing the loop: a 21-year audit of strategies for preventing stroke and death following carotid endarterectomy. ( Bell, PR; Bown, MJ; Dennis, MJ; London, NJ; McCarthy, MJ; Nasim, A; Naylor, AR; Sayers, RD, 2013)
"End-pouch ECA aneurysms were created in adult rats and were then embedded with either platinum or HydroCoils."3.83Aspirin and Clopidogrel Inhibit Aneurysm Healing after HydroCoil Implantation in External Carotid Artery Aneurysm Model. ( Chaudhary, N; Gemmete, JJ; Li, P; Pandey, AS; Thompson, BG; Xi, G; Zhang, C, 2016)
"The objective of this study was to compare nonresponders (NR) and responders (R) to clopidogrel with respect to presence of microvascular and macrovascular pathology in a cohort of patients with recent minor ischemic stroke (IS) or transient ischemic attack (TIA)."3.81Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease. ( Gigante, B; Höeg Dembrower, K; Jörneskog, G; Laska, AC; Laurencikas, E; Lundström, A; von Arbin, M; Wallén, H, 2015)
"9 years) with ischemic stroke or carotid artery stenting who received clopidogrel (75 mg) for >7 days at our hospital between October 2009 and March 2010."3.77Clopidogrel resistance and the effect of combination cilostazol in patients with ischemic stroke or carotid artery stenting using the VerifyNow P2Y12 Assay. ( Deguchi, I; Dembo, T; Fukuoka, T; Horiuchi, Y; Kato, Y; Maruyama, H; Nagoya, H; Takeda, H; Tanahashi, N, 2011)
" Preoperative treatment with clopidogrel, particularly when it is continued to the day before surgery, and postoperative arterial hypertension seem to be associated with a higher risk of neck bleeding after CEA, requiring re-exploration in most cases."3.77Predictors of neck bleeding after eversion carotid endarterectomy. ( Ballotta, E; Baracchini, C; Gruppo, M; Lorenzetti, R; Mazzalai, F; Meneghetti, G, 2011)
"The incidences of transient ischemic attack, stroke, or death at up to 30 days after CAS in the high-OTR patients were similar between groups 1 and 2 (P = ."2.79Antiplatelet effects of clopidogrel dose adjustment (75 mg/d vs 150 mg/d) after carotid stenting. ( Cayuela, A; González, A; Gonzalez-Marcos, JR; Mayol, A; Moniche, F; Montaner, J, 2014)
"Onyx HD-500 is a liquid embolic used to treat intracranial aneurysms."1.39Continued concern about parent vessel steno-occlusive progression with Onyx HD-500 and the utility of quantitative magnetic resonance imaging in serial assessment. ( Alaraj, A; Aletich, VA; Amin-Hanjani, S; Carlson, AP; Charbel, FT, 2013)
"8 patients with 9 spontaneous dissecting aneurysms of the cervical carotid artery--5 of which were symptomatic--plus one patient with ofthalmoplegia due to an aneurysm of the cavernous carotid artery were studied."1.34[Treatment of carotid artery aneurysms with covered stents]. ( Alfke, K; Bartsch, T; Dörner, L; Jansen, O; Rohr, A; Stingele, R, 2007)
"Ferric chloride has been widely used to induce arterial thrombosis in a variety of species."1.33An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. ( Wang, X; Xu, L, 2005)
"However, their effects on thrombus formation have rarely been evaluated in experimental animals in vivo."1.29In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis. ( Iwamoto, Y; Naritomi, H; Nishimura, H; Sugita, M; Tachibana, H, 1996)
"Ticlopidine was more effective in patients without carotid stenosis."1.28Prevention of stroke with ticlopidine: who benefits most? TASS Baseline and Angiographic Data Subgroup. ( Grotta, JC; Kamm, B; Norris, JW, 1992)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.38)18.2507
2000's6 (18.75)29.6817
2010's23 (71.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cvjetko, I1
Dovžak Bajs, I1
Bezjak, M1
Patti, G1
Tomai, F1
Melfi, R1
Ricottini, E1
Macrì, M1
Sedati, P1
Giardina, A1
Aurigemma, C1
Leporace, M1
D'Ambrosio, A1
Di Sciascio, G1
Thapar, A1
Jenkins, IH1
Mehta, A1
Davies, AH1
De Smit, E1
O'Sullivan, E1
Naylor, AR1
Sayers, RD1
McCarthy, MJ1
Bown, MJ1
Nasim, A1
Dennis, MJ1
London, NJ1
Bell, PR1
Brown, MM1
Mendiz, OA1
Fava, CM1
Lev, GA1
Valdivieso, LR1
Caponi, G1
Hidalgo Alava, GF1
Favaloro, RR1
Chalouhi, N1
Zanaty, M1
Tjoumakaris, S1
Gonzalez, LF1
Hasan, D1
Kung, D1
Rosenwasser, RH1
Jabbour, P1
González, A2
Moniche, F2
Cayuela, A2
Gonzalez-Marcos, JR2
Mayol, A2
Montaner, J2
Lundström, A1
Wallén, H1
von Arbin, M1
Jörneskog, G1
Gigante, B1
Höeg Dembrower, K1
Laurencikas, E1
Laska, AC1
García-Lozano, JR1
Torrecillas, F1
Escudero-Martínez, I1
Jones, DW1
Goodney, PP1
Conrad, MF1
Nolan, BW2
Rzucidlo, EM1
Powell, RJ1
Cronenwett, JL1
Stone, DH2
Furlong, CE1
Marsillach, J1
Jarvik, GP1
Costa, LG1
Zhang, C1
Li, P1
Xi, G1
Gemmete, JJ1
Chaudhary, N1
Thompson, BG1
Pandey, AS1
Duconge, J1
Hernandez-Suarez, DF1
Versaci, F1
Reimers, B1
Del Giudice, C1
Schofer, J1
Giacomin, A1
Saccà, S1
Gandini, R1
Albiero, R1
Pellegrino, A1
Bertoldo, F1
Simonetti, G1
Chiariello, L1
Hanna, EB1
Abu-Fadel, MS1
Maruyama, H1
Takeda, H1
Dembo, T1
Nagoya, H1
Kato, Y1
Fukuoka, T1
Deguchi, I1
Horiuchi, Y1
Tanahashi, N1
Baracchini, C1
Gruppo, M1
Mazzalai, F1
Lorenzetti, R1
Meneghetti, G1
Ballotta, E1
Jaberi, A1
Lum, C1
Stefanski, P1
Thornhill, RE1
Dowlatshahi, D1
Chechik, O1
Goldstein, Y1
Behrbalk, E1
Kaufman, E1
Rabinovich, Y1
Fang, YB1
Li, Q1
Yang, PF1
Huang, QH1
Zhao, WY1
Xu, Y1
Hong, B1
Liu, JM1
Carlson, AP1
Alaraj, A1
Amin-Hanjani, S1
Charbel, FT1
Aletich, VA1
Junghans, U1
Siebler, M1
Conforto, AB1
Puglia, P1
Yamamoto, FI1
Scaff, M1
Wang, X1
Xu, L1
Rohr, A1
Alfke, K1
Dörner, L1
Bartsch, T1
Stingele, R1
Jansen, O1
Weinberger, J1
Nishimura, H1
Naritomi, H1
Iwamoto, Y1
Tachibana, H1
Sugita, M1
Eachempati, SR1
Sebastian, MW1
Reed, RL1
Grotta, JC1
Norris, JW1
Kamm, B1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Two Different Pre-Intervention Therapeutic Strategies With Clopidogrel and Atorvastatin for the Prevention of Cerebral Damage During Carotid Artery Stenting. Armyda-Caro Randomized Trial.[NCT01572623]Phase 4150 participants (Anticipated)Interventional2011-07-31Recruiting
Prospective Evaluation for Hybrid Cardiac Procedures[NCT05143671]111 participants (Anticipated)Observational2021-05-13Recruiting
A Prospective, Nonrandomized, Study Comparing the Use of Aspirin and Intraoperative Blood Loss and Postoperative Complications Following Open Inguinal Hernia Repair.[NCT02084615]300 participants (Anticipated)Interventional2014-08-31Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for ticlopidine and Arterial Diseases, Carotid

ArticleYear
Diagnosis and management of carotid atherosclerosis.
    BMJ (Clinical research ed.), 2013, Mar-18, Volume: 346

    Topics: Carotid Artery Diseases; Carotid Artery, Common; Clopidogrel; Endarterectomy, Carotid; Female; Human

2013
Closing the loop: a 21-year audit of strategies for preventing stroke and death following carotid endarterectomy.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2013, Volume: 46, Issue:2

    Topics: Angioscopy; Aspirin; Carotid Artery Diseases; Clinical Protocols; Clopidogrel; Drug Therapy, Combina

2013
Aggressive medical therapy alone is not adequate in certain patients with severe symptomatic carotid stenosis.
    Stroke, 2013, Volume: 44, Issue:10

    Topics: Aspirin; Atorvastatin; Carotid Artery Diseases; Clopidogrel; Constriction, Pathologic; Endovascular

2013
Potential Usefulness of Clopidogrel Pharmacogenetics in Cerebral Endovascular Procedures and Carotid Artery Stenting.
    Current clinical pharmacology, 2017, Volume: 12, Issue:1

    Topics: Carotid Artery Diseases; Cerebrovascular Disorders; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resi

2017
Posttraumatic bilateral carotid artery and right vertebral artery dissections in a patient with fibromuscular dysplasia: case report and review of the literature.
    The Journal of trauma, 1998, Volume: 44, Issue:2

    Topics: Accidents, Traffic; Adult; Aortic Dissection; Aspirin; Carotid Artery Diseases; Female; Fibromuscula

1998

Trials

4 trials available for ticlopidine and Arterial Diseases, Carotid

ArticleYear
Strategies of clopidogrel load and atorvastatin reload to prevent ischemic cerebral events in patients undergoing protected carotid stenting. Results of the randomized ARMYDA-9 CAROTID (Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting
    Journal of the American College of Cardiology, 2013, Apr-02, Volume: 61, Issue:13

    Topics: Aged; Angioplasty, Balloon; Anticholesteremic Agents; Atorvastatin; Brain Ischemia; Carotid Artery D

2013
Aggressive medical therapy alone is not adequate in certain patients with severe symptomatic carotid stenosis.
    Stroke, 2013, Volume: 44, Issue:10

    Topics: Aspirin; Atorvastatin; Carotid Artery Diseases; Clopidogrel; Constriction, Pathologic; Endovascular

2013
Antiplatelet effects of clopidogrel dose adjustment (75 mg/d vs 150 mg/d) after carotid stenting.
    Journal of vascular surgery, 2014, Volume: 60, Issue:2

    Topics: Aged; Angioplasty; Blood Platelets; Carotid Artery Diseases; Clopidogrel; Female; Humans; Ischemic A

2014
Cerebral microembolism is blocked by tirofiban, a selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist.
    Circulation, 2003, Jun-03, Volume: 107, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carotid Artery Diseases; Clopidogrel; Female; Humans; Infus

2003

Other Studies

24 other studies available for ticlopidine and Arterial Diseases, Carotid

ArticleYear
[Carotid Endarterectomy in Patients with Antiaggregation Therapy].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2016, Volume: 70, Issue:2

    Topics: Aged; Anticoagulants; Carotid Artery Diseases; Clopidogrel; Croatia; Drug Therapy, Combination; Enda

2016
Giant cell arteritis can occur in the absence of a raised ESR.
    BMJ (Clinical research ed.), 2013, Apr-16, Volume: 346

    Topics: Carotid Artery Diseases; Endarterectomy, Carotid; Female; Humans; Magnetic Resonance Angiography; Ma

2013
Hybrid strategy for unstable patients with severe carotid and cardiac disease requiring surgery.
    Cardiology journal, 2015, Volume: 22, Issue:1

    Topics: Aged; Angioplasty, Balloon; Anticoagulants; Aspirin; Cardiac Surgical Procedures; Carotid Artery Dis

2015
Treatment of blister-like aneurysms with the pipeline embolization device.
    Neurosurgery, 2014, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty; Aspirin; Basilar Artery; Carotid Ar

2014
Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:10

    Topics: Aged; Blood Glucose; Carotid Artery Diseases; Cerebral Small Vessel Diseases; Clopidogrel; Cohort St

2015
Effect of CYP2C19 Polymorphisms on the Platelet Response to Clopidogrel and Influence on the Effect of High Versus Standard Dose Clopidogrel in Carotid Artery Stenting.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2016, Volume: 51, Issue:2

    Topics: Aged; Angioplasty; Blood Platelets; Carotid Artery Diseases; Clopidogrel; Cytochrome P-450 CYP2C19;

2016
Dual antiplatelet therapy reduces stroke but increases bleeding at the time of carotid endarterectomy.
    Journal of vascular surgery, 2016, Volume: 63, Issue:5

    Topics: Aged; Aspirin; Asymptomatic Diseases; Carotid Artery Diseases; Chi-Square Distribution; Clopidogrel;

2016
Paraoxonases-1, -2 and -3: What are their functions?
    Chemico-biological interactions, 2016, Nov-25, Volume: 259, Issue:Pt B

    Topics: Animals; Aryldialkylphosphatase; Astrocytes; Carotid Artery Diseases; Cells, Cultured; Clopidogrel;

2016
Aspirin and Clopidogrel Inhibit Aneurysm Healing after HydroCoil Implantation in External Carotid Artery Aneurysm Model.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:11

    Topics: Aneurysm; Animals; Aspirin; Carotid Artery Diseases; Carotid Artery, External; Cell Movement; Clopid

2016
Simultaneous hybrid revascularization by carotid stenting and coronary artery bypass grafting: the SHARP study.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Carotid Arteries; Carotid Artery Diseases; Clopidogrel; Corona

2009
Comment on "variations in the pharmacological management of patients treated with carotid endarterectomy: a survey of European vascular surgeons".
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2010, Volume: 39, Issue:6

    Topics: Aspirin; Carotid Artery Diseases; Clopidogrel; Endarterectomy, Carotid; Europe; Humans; Incidence; P

2010
Management of severe bilateral carotid artery stenosis concomitant to severely symptomatic coronary arterial disease requiring coronary artery bypass grafting: a case-based review.
    The Journal of invasive cardiology, 2010, Volume: 22, Issue:10

    Topics: Carotid Artery Diseases; Carotid Stenosis; Clopidogrel; Coronary Artery Bypass; Endarterectomy, Caro

2010
Clopidogrel resistance and the effect of combination cilostazol in patients with ischemic stroke or carotid artery stenting using the VerifyNow P2Y12 Assay.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:7

    Topics: Aged; Blood Coagulation Tests; Blood Platelets; Carotid Artery Diseases; Cilostazol; Clopidogrel; Dr

2011
Predictors of neck bleeding after eversion carotid endarterectomy.
    Journal of vascular surgery, 2011, Volume: 54, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carotid Artery Diseases; Chi-Square Distribution; Clopidogrel; Drug

2011
Computed tomography angiography evaluation of internal carotid artery free-floating thrombus--single-center diagnosis, false-positives, and follow-up.
    Emergency radiology, 2012, Volume: 19, Issue:4

    Topics: Aged; Anticoagulants; Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Clopidogrel; Diagn

2012
Blood loss and complications following carotid endarterectomy in patients treated with clopidogrel.
    Vascular, 2012, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Artery Diseases; Clopidogrel; Drug T

2012
Treatment of blood blister-like aneurysms of the internal carotid artery with stent-assisted coil embolization.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:7

    Topics: Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiography; Clopidogrel; Embol

2013
Continued concern about parent vessel steno-occlusive progression with Onyx HD-500 and the utility of quantitative magnetic resonance imaging in serial assessment.
    Neurosurgery, 2013, Volume: 72, Issue:3

    Topics: Angioplasty; Aspirin; Carotid Artery Diseases; Carotid Stenosis; Clopidogrel; Constriction, Patholog

2013
Progressive cervicocranial arteriopathy with dilatations and stenoses: case report.
    Arquivos de neuro-psiquiatria, 2004, Volume: 62, Issue:3B

    Topics: Adult; Arterial Occlusive Diseases; Aspirin; Basilar Artery; Carotid Artery Diseases; Carotid Artery

2004
An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research.
    Thrombosis research, 2005, Volume: 115, Issue:1-2

    Topics: Animals; Arterial Occlusive Diseases; Carotid Artery Diseases; Chlorides; Clopidogrel; Disease Model

2005
[Treatment of carotid artery aneurysms with covered stents].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2007, Volume: 179, Issue:10

    Topics: Adult; Alloys; Angiography, Digital Subtraction; Angioplasty; Aortic Dissection; Aspirin; Carotid Ar

2007
Antiplatelet agents for stroke prevention following transient ischemic attack.
    Southern medical journal, 2008, Volume: 101, Issue:1

    Topics: Angioplasty, Balloon; Aspirin; Carotid Artery Diseases; Clopidogrel; Dipyridamole; Drug Therapy, Com

2008
In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis.
    Stroke, 1996, Volume: 27, Issue:6

    Topics: Animals; Aspirin; Carotid Artery Diseases; Carotid Artery Injuries; Carotid Artery, Common; Cerebrov

1996
Prevention of stroke with ticlopidine: who benefits most? TASS Baseline and Angiographic Data Subgroup.
    Neurology, 1992, Volume: 42, Issue:1

    Topics: Aspirin; Carotid Artery Diseases; Cerebral Angiography; Cerebrovascular Disorders; Female; Humans; L

1992