ticlopidine has been researched along with Angiogenesis, Pathologic in 5 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stroke is the major cause of death and decrease in the activities of daily living." | 5.40 | Neurovascular protection of cilostazol in stroke-prone spontaneous hypertensive rats associated with angiogenesis and pericyte proliferation. ( Abe, K; Deguchi, K; Ikeda, Y; Kono, S; Kurata, T; Liu, N; Liu, W; Omote, Y; Yamashita, T, 2014) |
| "Although full platelet inhibition with aspirin and thienopyridines before coronary stenting has significantly reduced the risk of acute stent thrombosis, peri-procedural myonecrosis still occurs frequently and is associated with increased death rate." | 5.11 | Does pre-treatment with aspirin and loading dose clopidogrel obviate the need for glycoprotein IIb/IIIa antagonists during elective coronary stenting? A focus on peri-procedural myonecrosis. ( Bosmans, JM; Claeys, MJ; Michiels, JJ; Van Der Goten, P; Van der Planken, MG; Vertessen, F; Vrints, CJ; Wuyts, FL, 2005) |
| "Stroke is the major cause of death and decrease in the activities of daily living." | 1.40 | Neurovascular protection of cilostazol in stroke-prone spontaneous hypertensive rats associated with angiogenesis and pericyte proliferation. ( Abe, K; Deguchi, K; Ikeda, Y; Kono, S; Kurata, T; Liu, N; Liu, W; Omote, Y; Yamashita, T, 2014) |
| "Ticlopidine treatment resulted in increased platelet endostatin content and release." | 1.31 | Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release. ( Buret, A; Cirino, G; Elliott, SN; Ignarro, LJ; Ma, L; Wallace, JL, 2001) |
| "However, the number and size of lung metastases were reduced in treated animals when examined at the time of sacrifice." | 1.31 | Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model. ( Bergerat, JP; Cazenave, JP; Céraline, J; Chenard, MP; Deplanque, G; Klein-Soyer, C; Mah-Becherel, MC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omote, Y | 1 |
| Deguchi, K | 1 |
| Kono, S | 1 |
| Liu, N | 1 |
| Liu, W | 1 |
| Kurata, T | 1 |
| Yamashita, T | 1 |
| Ikeda, Y | 1 |
| Abe, K | 1 |
| Claeys, MJ | 1 |
| Van der Planken, MG | 1 |
| Bosmans, JM | 1 |
| Michiels, JJ | 1 |
| Vertessen, F | 1 |
| Van Der Goten, P | 1 |
| Wuyts, FL | 1 |
| Vrints, CJ | 1 |
| Klein-Soyer, C | 2 |
| Cazenave, JP | 2 |
| Herbert, JM | 1 |
| Maffrand, JP | 1 |
| Ma, L | 1 |
| Elliott, SN | 1 |
| Cirino, G | 1 |
| Buret, A | 1 |
| Ignarro, LJ | 1 |
| Wallace, JL | 1 |
| Mah-Becherel, MC | 1 |
| Céraline, J | 1 |
| Deplanque, G | 1 |
| Chenard, MP | 1 |
| Bergerat, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gastrointestinal Ulceration in Patients on Dual Antiplatelet Therapy After Percutaneous Coronary Intervention[NCT00413309] | 30 participants (Anticipated) | Interventional | 2006-04-30 | Completed | |||
| Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer[NCT02418312] | 228 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| Pantoprazole Versus Famotidine for the Prevention of Recurrent Peptic Ulcers in Thienopyridine Users - a Double-blind Randomized Controlled Trial[NCT02551744] | 101 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Follow-up endoscopy was performed at the end of the 6th month (NCT02418312)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Histamine-2 Receptor Antagonist Group | 106 |
| Placebo Group | 101 |
Follow-up endoscopy was performed at the end of the 6th month (NCT02551744)
Timeframe: six month
| Intervention | participants (Number) |
|---|---|
| Proton Pump Inhibitor Group | 1 |
| Histamine-2 Receptor Antagonist Group | 7 |
1 trial available for ticlopidine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Does pre-treatment with aspirin and loading dose clopidogrel obviate the need for glycoprotein IIb/IIIa antagonists during elective coronary stenting? A focus on peri-procedural myonecrosis.
Topics: Abciximab; Aged; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Diseas | 2005 |
4 other studies available for ticlopidine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Neurovascular protection of cilostazol in stroke-prone spontaneous hypertensive rats associated with angiogenesis and pericyte proliferation.
Topics: Animals; Antigens; Aspirin; Cerebrovascular Circulation; Cilostazol; Clopidogrel; Disease Models, An | 2014 |
SR 25989 inhibits healing of a mechanical wound of confluent human saphenous vein endothelial cells which is modulated by standard heparin and growth factors.
Topics: Cell Division; Cells, Cultured; Clopidogrel; Culture Media; Endothelium, Vascular; Fibroblast Growth | 1994 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood | 2001 |
Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Cell Division; Clopidogrel; Disease Models, Animal; Foot; G | 2002 |