ticlopidine has been researched along with Agranulocytosis in 27 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Agranulocytosis is a rare complication of ticlopidine and can be life-threatening." | 7.74 | Necrotizing gingivitis: a possible oral manifestation of ticlopidine-induced agranulocytosis. ( Fun, LC; Karim, F; Rahman, RA; Rajandram, RK; Ramli, R, 2007) |
| "Ticlopidine is associated with a relatively high incidence of agranulocytosis and aplastic anemia." | 7.70 | Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis. ( Liu, ZC; Uetrecht, JP, 2000) |
| "A 75-year-old female patient with agranulocytosis caused by ticlopidine is reported." | 7.68 | Agranulocytosis caused by ticlopidine and its mechanism. ( Kurohara, K; Ono, K; Shimamoto, Y; Yamaguchi, M; Yoshihara, M, 1991) |
| "Ticlopidine is an oral antiplatelet agent frequently utilized in the treatment of cerebrovascular disease." | 5.31 | Ticlopidine-induced severe agranulocytosis after the placement of coronary artery stent--a case report. ( Buyukberber, S; Sari, R; Sevinc, A, 2000) |
| "Agranulocytosis is a rare complication of ticlopidine and can be life-threatening." | 3.74 | Necrotizing gingivitis: a possible oral manifestation of ticlopidine-induced agranulocytosis. ( Fun, LC; Karim, F; Rahman, RA; Rajandram, RK; Ramli, R, 2007) |
| "Ticlopidine is associated with a relatively high incidence of agranulocytosis and aplastic anemia." | 3.70 | Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis. ( Liu, ZC; Uetrecht, JP, 2000) |
| " We report a patient with long-standing psoriasis vulgaris who showed rapid improvement during agranulocytosis caused by ticlopidine." | 3.70 | Rapid improvement of psoriasis vulgaris during drug-induced agranulocytosis. ( Furukawa, F; Tachibana, T; Toichi, E, 2000) |
| "G-CSF was applied in three patients with acute, iatrogenic, immunological agranulocytosis (after ticlopidine, thimazol and aminoglutethimide) complicated by severe infections." | 3.69 | [Treatment of drug induced agranulocytosis with granulocyte-macrophage colony stimulating factor (G-CSF)]. ( Kotlarek-Haus, S; Podolak-Dawidziak, M; Wróbel, T, 1994) |
| "Four cases of bone marrow aplasia, with temporary agranulocytosis (one of them fatal) are described in patients treated with Ticlopidine, an anti-aggregating drug prescribed for prevention of thromboembolic disease." | 3.66 | [Hematological toxicity of ticlopidine? (author's transl)]. ( Bauters, F; Canuel, C; de Gramont, A; Degos, L; Krulik, M; Marty, M; Najean, Y, 1982) |
| "Idiosyncratic drug-induced agranulocytosis is characterized by a neutrophil count <0." | 2.43 | [Idiosyncratic drug-induced agranulocytosis]. ( Andrès, E; Maloisel, F, 2006) |
| "Ticlopidine-induced aplastic anemia (TIAA) is considered very uncommon." | 2.41 | Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases. ( Fragopanagou, E; Galani, A; Giannakoulas, N; Kouraklis-Symeonidis, A; Matsouka, P; Seimeni, U; Symeonidis, A; Tiniakou, M; Zoumbos, N, 2002) |
| "Drug-induced agranulocytosis is a rare but life-threatening side effect which is possibly based on immunogenetic mechanisms." | 1.33 | Drug-induced agranulocytosis: impact of different fcgamma receptor polymorphisms? ( Cascorbi, I; Dettling, M; Krüger, T; Mosyagin, I; Schaub, R, 2005) |
| "Ticlopidine is an oral antiplatelet agent frequently utilized in the treatment of cerebrovascular disease." | 1.31 | Ticlopidine-induced severe agranulocytosis after the placement of coronary artery stent--a case report. ( Buyukberber, S; Sari, R; Sevinc, A, 2000) |
| "Agranulocytosis is one of the most serious side effects to drugs." | 1.30 | [Drug-induced agranulocytosis: clinical study of 19 cases]. ( Alvarez, C; Amutio, E; Cortés, C; Márquez, JA; Pardo, C; Piñán, MA, 1998) |
| "The few cases of reversible agranulocytosis reported in the literature might be due to the inhibition of myelopoiesis in patients with medullary reserves already impaired." | 1.27 | [Bone marrow culture in patients treated with Ticlopidine]. ( Charbonnier, R; Pistone, MA; Resegotti, L; Testa, D; Toselli, P; Vivalda, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 11 (40.74) | 18.2507 |
| 2000's | 10 (37.04) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Symeonidis, A | 1 |
| Kouraklis-Symeonidis, A | 1 |
| Seimeni, U | 1 |
| Galani, A | 1 |
| Giannakoulas, N | 1 |
| Fragopanagou, E | 1 |
| Tiniakou, M | 1 |
| Matsouka, P | 1 |
| Zoumbos, N | 1 |
| Andrès, E | 1 |
| Maloisel, F | 1 |
| Mosyagin, I | 1 |
| Cascorbi, I | 1 |
| Schaub, R | 1 |
| Krüger, T | 1 |
| Dettling, M | 1 |
| Kummer, O | 1 |
| Haschke, M | 1 |
| Tuchscherer, D | 1 |
| Lampert, M | 1 |
| Martius, F | 1 |
| Krähenbühl, S | 1 |
| Rajandram, RK | 1 |
| Ramli, R | 1 |
| Karim, F | 1 |
| Rahman, RA | 1 |
| Fun, LC | 1 |
| de Fraiture, WH | 1 |
| Claas, FH | 1 |
| Meyboom, RH | 1 |
| de Gramont, A | 1 |
| Canuel, C | 1 |
| Krulik, M | 1 |
| Bauters, F | 1 |
| Degos, L | 1 |
| Marty, M | 1 |
| Najean, Y | 1 |
| Kotlarek-Haus, S | 1 |
| Podolak-Dawidziak, M | 1 |
| Wróbel, T | 1 |
| Legarra, G | 1 |
| Beltrán de Heredia, JM | 1 |
| Olabarría, I | 1 |
| Menoyo, MV | 1 |
| Villarreal, JJ | 1 |
| Shear, NH | 1 |
| Appel, C | 1 |
| Lesesve, JF | 1 |
| Callat, MP | 1 |
| Lenormand, B | 1 |
| Monconduit, M | 1 |
| Noblet, C | 1 |
| Moore, N | 1 |
| Caron, F | 1 |
| Humbert, G | 1 |
| Stamatoullas, A | 1 |
| Tilly, H | 1 |
| Schneider, AW | 1 |
| Fechler, L | 1 |
| Gilfrich, HJ | 1 |
| Johanning, RJ | 1 |
| Tschida, SJ | 1 |
| Haushofer, A | 1 |
| Halbmayer, WM | 1 |
| Prachar, H | 1 |
| Sánchez Ayuso, J | 1 |
| Fernández González, F | 1 |
| Fernández Rodríguez, E | 1 |
| Márquez, JA | 1 |
| Pardo, C | 1 |
| Amutio, E | 1 |
| Cortés, C | 1 |
| Piñán, MA | 1 |
| Alvarez, C | 1 |
| Liu, ZC | 1 |
| Uetrecht, JP | 1 |
| Toichi, E | 1 |
| Tachibana, T | 1 |
| Furukawa, F | 1 |
| Sari, R | 1 |
| Sevinc, A | 1 |
| Buyukberber, S | 1 |
| Alter, P | 1 |
| Schaefer, JR | 1 |
| Maisch, B | 1 |
| Fernández Esteban, V | 1 |
| Cuevas Ruiz, B | 1 |
| Cuevas Ruiz, MV | 1 |
| Saralegui Reta, I | 1 |
| Ochoa Gómez, J | 1 |
| del Rey Moreno, J | 1 |
| López Cortés, LF | 1 |
| Gómez Mateos, JM | 1 |
| Lozano de León, F | 1 |
| Ono, K | 1 |
| Kurohara, K | 1 |
| Yoshihara, M | 1 |
| Shimamoto, Y | 1 |
| Yamaguchi, M | 1 |
| Montanari, G | 1 |
| Mussida, M | 1 |
| Scarabelli, C | 1 |
| Zinzalini, G | 1 |
| Guerciolini, R | 1 |
| Giordano, G | 1 |
| Aversa, F | 1 |
| Del Favero, A | 1 |
| Marmont, AM | 1 |
| Lotti, G | 1 |
| Nati, S | 1 |
| Martinengo, M | 1 |
| Morgano, A | 1 |
| Resegotti, L | 1 |
| Pistone, MA | 1 |
| Testa, D | 1 |
| Charbonnier, R | 1 |
| Toselli, P | 1 |
| Vivalda, S | 1 |
2 reviews available for ticlopidine and Agranulocytosis
| Article | Year |
|---|---|
Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases.
Topics: Age Distribution; Aged; Aged, 80 and over; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; | 2002 |
[Idiosyncratic drug-induced agranulocytosis].
Topics: Agranulocytosis; Anti-Bacterial Agents; Antithyroid Agents; Diagnosis, Differential; Fever; Fibrinol | 2006 |
25 other studies available for ticlopidine and Agranulocytosis
| Article | Year |
|---|---|
Drug-induced agranulocytosis: impact of different fcgamma receptor polymorphisms?
Topics: Adult; Agranulocytosis; Antipsychotic Agents; Antithyroid Agents; Clozapine; DNA; Female; Fibrinolyt | 2005 |
[Agranulocytosis in a patient treated with metamizole and clopidogrel].
Topics: Aged; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow; Cerebral Infarction; Cl | 2006 |
Necrotizing gingivitis: a possible oral manifestation of ticlopidine-induced agranulocytosis.
Topics: Agranulocytosis; Biopsy, Needle; Diagnosis, Differential; Female; Follow-Up Studies; Gingivitis, Nec | 2007 |
[Side effects of ticlopidine; clinical observation and immunological study].
Topics: Aged; Agranulocytosis; Antibodies; Drug Eruptions; Female; Humans; Male; Middle Aged; Purpura, Throm | 1982 |
[Hematological toxicity of ticlopidine? (author's transl)].
Topics: Aged; Agranulocytosis; Female; Humans; Male; Middle Aged; Pancytopenia; Platelet Aggregation; Thioph | 1982 |
[Treatment of drug induced agranulocytosis with granulocyte-macrophage colony stimulating factor (G-CSF)].
Topics: Adult; Agranulocytosis; Aminoglutethimide; Female; Granulocyte Colony-Stimulating Factor; Humans; Le | 1994 |
[Agranulocytosis caused by ticlopidine].
Topics: Agranulocytosis; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Middle | 1994 |
Prevention of ischemic stroke.
Topics: Aged; Aged, 80 and over; Agranulocytosis; Anemia, Aplastic; Cerebrovascular Disorders; Female; Human | 1995 |
Hematological toxicity of ticlopidine.
Topics: Aged; Agranulocytosis; Anemia, Aplastic; Humans; Incidence; Male; Middle Aged; Ticlopidine | 1994 |
[Ticlopidine-induced pancytopenia: therapy of agranulocytosis with granulocyte colony stimulating factor].
Topics: Aged; Agranulocytosis; Biopsy, Needle; Bone Marrow; Dose-Response Relationship, Drug; Drug Administr | 1996 |
Comment: Pseudomonas bacteremia secondary to ticlopidine-induced agranulocytosis.
Topics: Aged; Aged, 80 and over; Agranulocytosis; Female; Humans; Pseudomonas Infections; Ticlopidine | 1996 |
Neutropenia with ticlopidine plus aspirin.
Topics: Agranulocytosis; Aspirin; Coronary Disease; Humans; Monitoring, Physiologic; Neutropenia; Platelet A | 1997 |
[Ticlopidine and bone marrow aplasia].
Topics: Adverse Drug Reaction Reporting Systems; Agranulocytosis; Anemia, Aplastic; Fibrinolytic Agents; Hum | 1997 |
[Drug-induced agranulocytosis: clinical study of 19 cases].
Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Dipyrone; Female; Granulocyte Colony-Stimulating Fa | 1998 |
Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis.
Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Glutathione; Humans; Hypochlorous Acid; Ne | 2000 |
Rapid improvement of psoriasis vulgaris during drug-induced agranulocytosis.
Topics: Aged; Agranulocytosis; Biopsy; Cerebral Infarction; Humans; Leukocyte Count; Male; Neutrophils; Plat | 2000 |
Ticlopidine-induced severe agranulocytosis after the placement of coronary artery stent--a case report.
Topics: Agranulocytosis; Coronary Disease; Female; Granulocyte Colony-Stimulating Factor; Humans; Middle Age | 2000 |
[Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis].
Topics: Agranulocytosis; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Clarithromycin; Coronary Dis | 2000 |
[Agranulocytosis and ticlopidine].
Topics: Aged; Agranulocytosis; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
[Agranulocytosis caused by ticlopidine].
Topics: Agranulocytosis; Humans; Hyperlipoproteinemia Type IV; Male; Middle Aged; Ticlopidine | 1992 |
Agranulocytosis caused by ticlopidine and its mechanism.
Topics: Aged; Agranulocytosis; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Female; Humans; L | 1991 |
[Mainly neutropenic pancytopenia caused by acute bone marrow depression during ticlopidine treatment].
Topics: Aged; Agranulocytosis; Anemia, Aplastic; Bone Marrow; Female; Humans; Neutropenia; Ticlopidine | 1987 |
Anaemia and agranulocytosis associated with ticlopidine therapy.
Topics: Agranulocytosis; Anemia; Blood Protein Electrophoresis; Bone Marrow Examination; Cells, Cultured; Fe | 1985 |
[Agranulocytosis caused by ticlopidine].
Topics: Aged; Agranulocytosis; Anticoagulants; Bone Marrow; Female; Humans; Male; Middle Aged; Thiophenes; T | 1985 |
[Bone marrow culture in patients treated with Ticlopidine].
Topics: Adult; Aged; Agranulocytosis; Alprostadil; Anticoagulants; Bone Marrow; Cells, Cultured; Colony-Form | 1985 |