ticlopidine has been researched along with Acute Lung Injury in 4 studies
Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
ticlopidine : A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral reversible platelet P2Y12 receptor inhibitors (ticagrelor and elinogrel) cause double-digit rates of dyspnea, while irreversible oral antiplatelet drugs (aspirin, ticlopidoine, clopidogrel, and prasugrel) or intravenous glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, or tirofiban) do not increase the incidence of dyspnea in randomized trials." | 8.90 | Dyspnea and reversibility of antiplatelet agents: ticagrelor, elinogrel, cangrelor, and beyond. ( DiNicolantonio, JJ; Serebruany, VL; Sibbing, D, 2014) |
| "Pretreatment with isoflurane abrogated ALI as measured by both BAL fluid protein and pulmonary immunofluorescence (P < ." | 5.38 | Isoflurane prevents acute lung injury through ADP-mediated platelet inhibition. ( Banerjee, A; Fragoso, M; Gamboni, F; Harr, JN; Jones, WL; Moore, EE; Silliman, CC; Stringham, J; Wohlauer, MV, 2012) |
| "Oral reversible platelet P2Y12 receptor inhibitors (ticagrelor and elinogrel) cause double-digit rates of dyspnea, while irreversible oral antiplatelet drugs (aspirin, ticlopidoine, clopidogrel, and prasugrel) or intravenous glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, or tirofiban) do not increase the incidence of dyspnea in randomized trials." | 4.90 | Dyspnea and reversibility of antiplatelet agents: ticagrelor, elinogrel, cangrelor, and beyond. ( DiNicolantonio, JJ; Serebruany, VL; Sibbing, D, 2014) |
| "Using a mouse model of intra-abdominal sepsis and acute lung injury, we investigated the role of the P2Y12 receptor in neutrophil migration and lung inflammation in P2Y12 null mice and in mice pretreated with the P2Y12 antagonist clopidogrel." | 3.83 | P2Y12 Receptor Modulates Sepsis-Induced Inflammation. ( Kilpatrick, LE; Kunapuli, SP; Liverani, E; Rico, MC; Tsygankov, AY, 2016) |
| "Use of aspirin (acetylsalicylic acid [ASA]) was found to improve outcome in animal models of acute lung injury (ALI) or its more severe form, acute respiratory distress syndrome." | 3.79 | High-dose acetylsalicylic acid is superior to low-dose as well as to clopidogrel in preventing lipopolysaccharide-induced lung injury in mice. ( Hegeman, MA; Jongsma, G; Juffermans, NP; Müller, MC; Tuinman, PR, 2013) |
| "Pretreatment with isoflurane abrogated ALI as measured by both BAL fluid protein and pulmonary immunofluorescence (P < ." | 1.38 | Isoflurane prevents acute lung injury through ADP-mediated platelet inhibition. ( Banerjee, A; Fragoso, M; Gamboni, F; Harr, JN; Jones, WL; Moore, EE; Silliman, CC; Stringham, J; Wohlauer, MV, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tuinman, PR | 1 |
| Müller, MC | 1 |
| Jongsma, G | 1 |
| Hegeman, MA | 1 |
| Juffermans, NP | 1 |
| Serebruany, VL | 1 |
| Sibbing, D | 1 |
| DiNicolantonio, JJ | 1 |
| Liverani, E | 1 |
| Rico, MC | 1 |
| Tsygankov, AY | 1 |
| Kilpatrick, LE | 1 |
| Kunapuli, SP | 1 |
| Harr, JN | 1 |
| Moore, EE | 1 |
| Stringham, J | 1 |
| Wohlauer, MV | 1 |
| Fragoso, M | 1 |
| Jones, WL | 1 |
| Gamboni, F | 1 |
| Silliman, CC | 1 |
| Banerjee, A | 1 |
1 review available for ticlopidine and Acute Lung Injury
| Article | Year |
|---|---|
Dyspnea and reversibility of antiplatelet agents: ticagrelor, elinogrel, cangrelor, and beyond.
Topics: Acute Lung Injury; Adenosine; Adenosine Monophosphate; Administration, Oral; Clopidogrel; Dyspnea; H | 2014 |
3 other studies available for ticlopidine and Acute Lung Injury
| Article | Year |
|---|---|
High-dose acetylsalicylic acid is superior to low-dose as well as to clopidogrel in preventing lipopolysaccharide-induced lung injury in mice.
Topics: Acute Lung Injury; Animals; Aspirin; Blood Platelets; Bronchoalveolar Lavage Fluid; Clopidogrel; Lip | 2013 |
P2Y12 Receptor Modulates Sepsis-Induced Inflammation.
Topics: Acute Lung Injury; Animals; Blood Platelets; Clopidogrel; Cytokines; Genetic Predisposition to Disea | 2016 |
Isoflurane prevents acute lung injury through ADP-mediated platelet inhibition.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Blood Platelets; Clopidogrel; Fluorescent Antib | 2012 |