Page last updated: 2024-08-25

tianeptine and Disease Models, Animal

tianeptine has been researched along with Disease Models, Animal in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (8.82)18.2507
2000's8 (23.53)29.6817
2010's20 (58.82)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Borgwardt, S; Costina, V; Djordjević, S; Filipović, D; Findeisen, P; Gass, P; Inta, D; Perić, I1
Estill, M; Javitch, JA; Pekarskaya, EA; Sakloth, F; Serafini, RA; Shen, L; Zachariou, V1
Barski, JJ; Bielecka-Wajdman, AM; Kasprowska, D; Małecki, A; Nowacka-Chmielewska, MM; Obuchowicz, E; Paul-Samojedny, M1
Han, SM; Jo, HU; Kim, YH; Kwak, JA; Park, HJ1
Benstaali, C; Cho, Y; Choquet, D; Coussen, F; Daburon, S; David, DJ; Grillo-Bosch, D; Humeau, Y; Sainlos, M; Saudou, F; Vincent, J; Zala, D; Zhang, C; Zhang, H1
Kim, BJ; Kim, CW; Kim, DH; Kim, HM; Kim, MY; Lee, MS; Lim, YY; Mun, SK; Park, SR; Seo, SK; Son, IP1
Banach, M; Borowicz, KK; Czuczwar, SJ; Piskorska, B1
Almeida, OF; Alves, ND; Beckers, J; Bessa, JM; Correia, JS; Irmler, M; Korostynski, M; Machado-Santos, AR; Mateus-Pinheiro, A; Morais, M; Patrício, P; Piechota, M; Pinto, L; Sousa, N; Stoffel, R1
Dudka, J; Kasperek, R; Nowak, G; Poleszak, E; Serefko, A; Wlaź, A; Wlaź, P; Wośko, S; Wróbel, A1
Cavalla, D; Chianelli, F; Gourine, AV; Hosford, PS; Korsak, A; Marina, N1
Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E1
Baek, JH; Cho, HY; Kim, GM; Kim, YH; Lee, CH; Lee, JG; Mansur, RB; McIntyre, RS; Park, SW; Seo, MK; Woo, YS1
Chattarji, S; Diamond, DM; Fuchs, E; Jay, TM; McEwen, BS; Reagan, LP; Svenningsson, P1
Chen, JY; Chu, CC; Ho, ST; Hsing, CH; Shieh, JP; Shui, HA; Tzeng, JI; Wang, JJ1
Ai, YX; Chen, FY; Li, YG; Liu, LJ; Liu, W; Shu, XJ; Sun, XH; Zhao, H; Zhu, C1
Choi, JI; Jeong, HJ; Kim, WM; Lee, HG; Lee, SH; Yoon, MH1
Bilge, SS; Bozkurt, A; Ciftcioğlu, E; Ilkaya, F; Kesim, Y; Uzbay, TI1
Delagrange, P; Elizalde, N; García-García, AL; Tordera, RM; Venzala, E1
Aigner, L; Gaburro, S; Irschick, R; Kandasamy, M; Klimaschewski, L; Landgraf, R; Sah, A; Sartori, SB; Schmuckermair, C; Singewald, N1
Akar, F; Celikyurt, IK; Erden, F; Gumuslu, E; Kır, HM; Kokturk, S; Mutlu, O; Ulak, G1
Fadel, JR; Grillo, CA; Hagar, JM; Piroli, GG; Reagan, LP; Reznikov, LR1
Diamond, DM; Fleshner, M; Zoladz, PR1
Casolini, P; Darnaudery, M; Koehl, M; Maccari, S; Morley-Fletcher, S; Van Reeth, O1
Czéh, B; Fuchs, E; Lucassen, PJ1
Czéh, B; de Biurrun, G; Frahm, J; Fuchs, E; Michaelis, T; Watanabe, T1
Celik, T; Kayir, H; Uzbay, T; Yüksel, N1
Besson, G; Chritin, M; Savasta, M1
Breivik, T; Fonnum, F; Gjermo, P; Gundersen, Y; Murison, R; Myhrer, T; Opstad, PK; Osmundsen, H; von Hörsten, S1
Ceyhan, M; Kayir, H; Uzbay, TI1
Campbell, AM; Diamond, DM; Fleshner, M; Muñoz, C; Park, CR; Zoladz, PR1
Martin, P; Puech, AJ; Thiébot, MH1
Curzon, G; Kennett, GA; Sarna, GS; Whitton, PS1
Curzon, G; Datla, KP; Sarna, GS; Whitton, PS1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1

Reviews

2 review(s) available for tianeptine and Disease Models, Animal

ArticleYear
The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation.
    Molecular psychiatry, 2010, Volume: 15, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; Brain; Cognition Disorders; Depression; Disease Models, Animal; Glutamic Acid; Humans; Neuronal Plasticity; Stress, Psychological; Thiazepines

2010
Animal behavioural studies in the evaluation of antidepressant drugs.
    The British journal of psychiatry. Supplement, 1992, Issue:15

    Topics: Animals; Antidepressive Agents, Tricyclic; Arousal; Brain; Depression; Disease Models, Animal; Helplessness, Learned; Impulsive Behavior; Neurotransmitter Agents; Restraint, Physical; Stress, Physiological; Thiazepines

1992

Other Studies

32 other study(ies) available for tianeptine and Disease Models, Animal

ArticleYear
Tianeptine modulates synaptic vesicle dynamics and favors synaptic mitochondria processes in socially isolated rats.
    Scientific reports, 2021, 09-07, Volume: 11, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Drug Evaluation, Preclinical; Gene Expression Regulation; Hippocampus; Male; Mitochondria; Nerve Tissue Proteins; Nootropic Agents; Protein Interaction Mapping; Proteome; Rats; Rats, Wistar; Signal Transduction; Social Isolation; Synaptic Vesicles; Thiazepines

2021
Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:11

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Disease Models, Animal; Humans; Hyperalgesia; Mice; Neuralgia

2023
The effects of desipramine, fluoxetine, or tianeptine on changes in bulbar BDNF levels induced by chronic social instability stress and inflammation.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:3

    Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Desipramine; Disease Models, Animal; Female; Fluoxetine; Inflammation; Lipopolysaccharides; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Thiazepines

2017
Tianeptine Reduces Mechanical Allodynia in Spinal Nerve-ligated and Chemotherapy-induced Neuropathic Mice.
    Pain physician, 2017, Volume: 20, Issue:4

    Topics: Activating Transcription Factor 3; Analgesics; Animals; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Rats, Sprague-Dawley; Spinal Nerves; Thiazepines; Vincristine

2017
Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models.
    Nature communications, 2018, 10-15, Volume: 9, Issue:1

    Topics: Animals; Brain-Derived Neurotrophic Factor; Diffusion; Disease Models, Animal; Hippocampus; Huntington Disease; Long-Term Potentiation; Memory; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Neuronal Plasticity; Protein Transport; Receptor, trkB; Receptors, AMPA; Signal Transduction; Synapses; Thiazepines

2018
Inhibitory effect of tianeptine on catagen induction in alopecia areata-like lesions induced by ultrasonic wave stress in mice.
    Clinical and experimental dermatology, 2013, Volume: 38, Issue:7

    Topics: Alopecia Areata; Animals; Antidepressive Agents, Tricyclic; Cell Cycle; Disease Models, Animal; Female; Hair Follicle; Immunohistochemistry; Mice; Mice, Inbred C57BL; Stress, Psychological; Thiazepines

2013
Effect of acute and chronic tianeptine on the action of classical antiepileptics in the mouse maximal electroshock model.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:2

    Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Avoidance Learning; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroshock; Epilepsy; Fluorescence Polarization; Male; Memory; Memory Disorders; Mice; Thiazepines; Tissue Distribution

2013
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:2

    Topics: Acetamides; Animals; Antidepressive Agents; Chronic Disease; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Fluoxetine; Gene Expression; Imipramine; Male; Neurons; Random Allocation; Rats, Wistar; Stress, Psychological; Thiazepines; Uncertainty

2015
The effects of ifenprodil on the activity of antidepressant drugs in the forced swim test in mice.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:6

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drug Synergism; Fluoxetine; Imipramine; Mice; Morpholines; Piperidines; Reboxetine; Swimming; Thiazepines

2014
Tianeptine prevents respiratory depression without affecting analgesic effect of opiates in conscious rats.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Animals; Dioxanes; Dioxoles; Disease Models, Animal; Excitatory Amino Acid Agonists; Lung; Male; Morphine; Pain Threshold; Phosphorylation; Piperidines; Plethysmography, Whole Body; Rats, Sprague-Dawley; Receptors, AMPA; Respiration; Respiratory Insufficiency; Thiazepines; Time Factors

2015
The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Anxiety; Behavior, Animal; Brain; Depression; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Female; Hippocampus; Imipramine; Mitochondria; Mitochondrial Proteins; Pregnancy; Prenatal Exposure Delayed Effects; Proteome; Rats, Sprague-Dawley; Thiazepines

2016
Tianeptine induces mTORC1 activation in rat hippocampal neurons under toxic conditions.
    Psychopharmacology, 2016, Volume: 233, Issue:13

    Topics: Animals; Antidepressive Agents, Tricyclic; Dendrites; Disease Models, Animal; Hippocampus; Mechanistic Target of Rapamycin Complex 1; Neurites; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Synapses; Synaptophysin; Thiazepines; TOR Serine-Threonine Kinases

2016
Tianeptine reduces morphine antinociceptive tolerance and physical dependence.
    Behavioural pharmacology, 2010, Volume: 21, Issue:5-6

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Thiazepines

2010
Tianeptine reverses stress-induced asymmetrical hippocampal volume and N-acetylaspartate loss in rats: an in vivo study.
    Psychiatry research, 2011, Dec-30, Volume: 194, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Aspartic Acid; Choline; Chromatography, High Pressure Liquid; Corticosterone; Creatine; Disease Models, Animal; Exploratory Behavior; Hippocampus; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Sprague-Dawley; Statistics as Topic; Stress, Psychological; Thiazepines

2011
The analgesic activity of intrathecal tianeptine, an atypical antidepressant, in a rat model of inflammatory pain.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:3

    Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Disease Models, Animal; Inflammation Mediators; Injections, Spinal; Male; Pain; Random Allocation; Rats; Rats, Sprague-Dawley; Thiazepines

2012
The antinociceptive effects of intravenous tianeptine in colorectal distension-induced visceral pain in rats: the role of 5-HT₃ receptors.
    European journal of pharmacology, 2012, Apr-15, Volume: 681, Issue:1-3

    Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Thiazepines; Time Factors; Visceral Pain

2012
Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factors.
    Psychopharmacology, 2012, Volume: 224, Issue:2

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Cyclohexanols; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Risk Factors; RNA, Messenger; Social Behavior; Stress, Psychological; Thiazepines; Venlafaxine Hydrochloride; Vesicular Glutamate Transport Protein 1

2012
Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior.
    Translational psychiatry, 2012, Oct-16, Volume: 2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Biomarkers; Dentate Gyrus; Depression; Disease Models, Animal; Female; Fluoxetine; Mice; Neurogenesis; Piperidines; Recurrence; Remission Induction; Thiazepines

2012
Effects of fluoxetine, tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice.
    Life sciences, 2012, Dec-17, Volume: 91, Issue:25-26

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Depression; Disease Models, Animal; Fluoxetine; Injections, Intraperitoneal; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Olanzapine; Stress, Psychological; Thiazepines

2012
Tianeptine modulates amygdalar glutamate neurochemistry and synaptic proteins in rats subjected to repeated stress.
    Experimental neurology, 2013, Volume: 241

    Topics: Amygdala; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Immunoprecipitation; Male; Membrane Proteins; Microdialysis; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Stress, Psychological; Thiazepines; Time Factors

2013
Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jul-01, Volume: 44

    Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Anxiety; Blood Pressure; Cats; Clonidine; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; Hypertension; Male; Maze Learning; Memory Disorders; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Stress Disorders, Post-Traumatic; Thiazepines

2013
Prenatal stress in rats predicts immobility behavior in the forced swim test. Effects of a chronic treatment with tianeptine.
    Brain research, 2003, Nov-07, Volume: 989, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Disease Models, Animal; Female; Immobilization; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stress, Physiological; Swimming; Thiazepines; Time Factors

2003
Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex.
    Biological psychiatry, 2004, Apr-15, Volume: 55, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Apoptosis; Body Weight; Cell Count; Dentate Gyrus; Depression; Disease Models, Animal; Fluorescent Dyes; In Situ Nick-End Labeling; Male; Stilbamidines; Stress, Psychological; Temporal Lobe; Thiazepines; Time Factors; Tupaiidae

2004
Synaptic plasticity and tianeptine: structural regulation.
    European psychiatry : the journal of the Association of European Psychiatrists, 2002, Volume: 17 Suppl 3

    Topics: Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Antimetabolites; Bromodeoxyuridine; Dentate Gyrus; Depressive Disorder, Major; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Immunohistochemistry; Male; Pilot Projects; Stress, Psychological; Synaptic Transmission; Thiazepines; Tupaia

2002
Acute and chronic tianeptine treatments attenuate ethanol withdrawal syndrome in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Central Nervous System Depressants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Reflex; Ethanol; Male; Rats; Rats, Wistar; Reaction Time; Substance Withdrawal Syndrome; Thiazepines

2006
Benefit of tianeptine and morphine in a transgenic model of familial amyotrophic lateral sclerosis.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2006, Volume: 7, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Drug Combinations; Injections, Intraperitoneal; Male; Mice; Mice, Transgenic; Morphine; Recovery of Function; Superoxide Dismutase; Survival Rate; Thiazepines; Treatment Outcome

2006
Enhanced susceptibility to periodontitis in an animal model of depression: reversed by chronic treatment with the anti-depressant tianeptine.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:7

    Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Disease Susceptibility; Inflammation Mediators; Ligation; Lipopolysaccharides; Male; Neurogenic Inflammation; Neuroimmunomodulation; Olfactory Bulb; Periodontitis; Rats; Rats, Wistar; Statistics, Nonparametric; Thiazepines

2006
Effects of tianeptine on onset time of pentylenetetrazole-induced seizures in mice: possible role of adenosine A1 receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain; Caffeine; Convulsants; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Male; Mice; Pentylenetetrazole; Reaction Time; Receptor, Adenosine A1; Thiazepines; Time Factors; Xanthines

2007
Pre-training administration of tianeptine, but not propranolol, protects hippocampus-dependent memory from being impaired by predator stress.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Predatory Behavior; Propranolol; Rats; Rats, Sprague-Dawley; Stress, Psychological; Thiazepines

2008
The effects of tianeptine and other antidepressants on a rat model of depression.
    The British journal of psychiatry. Supplement, 1992, Issue:15

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arousal; Brain; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Thiazepines

1992
Effects of tianeptine on stress-induced behavioural deficits and 5-HT dependent behaviour.
    Psychopharmacology, 1991, Volume: 104, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Disease Models, Animal; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serotonin; Stress, Psychological; Thiazepines

1991
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020