tiagabine has been researched along with Epilepsy in 118 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 55 (46.61) | 18.2507 |
| 2000's | 53 (44.92) | 29.6817 |
| 2010's | 7 (5.93) | 24.3611 |
| 2020's | 3 (2.54) | 2.80 |
| Authors | Studies |
|---|---|
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Ahmad, T; Alasmari, AF; Alasmari, F; Alqahtani, F; Alqarni, SA; Anjum, SMM; Ashraf, W; Imran, I; Javaid, S; Rasool, MF | 1 |
| Fijałkowski, Ł; Grześk, G; Kowalska, M; Kubacka, M; Nowaczyk, A; Nowaczyk, J; Sałat, K | 1 |
| Clausen, RP; Frølund, B; Krogsgaard-Larsen, P; Schousboe, A; Wellendorph, P | 1 |
| Choubey, PK; Seth, A; Sharma, PA; Shrivastava, SK; Srivastava, P; Tripathi, A; Tripathi, PN | 1 |
| Abou-Khalil, BW; Arain, A; Azar, NJ; Bangalore-Vittal, N | 1 |
| Lee, CY; Liou, HH | 1 |
| Faught, E; Fix, A; French, JA; Harden, CL; Kanner, AM; Montouris, G; Morris, GL; Vossler, DG | 1 |
| Błaszczyk, B | 1 |
| Auvinen, A; Fallah, M; Keränen, T; Peltola, J; Peltola, M; Raitanen, J | 1 |
| Krzyzanowski, M; Luszczki, JJ; Swiader, MJ | 1 |
| Pellock, JM | 4 |
| Ali, F; Cavanna, AE; McCorry, D; Rickards, HE | 1 |
| Endo, Y; Fueta, Y; Mita, T; Ohno, K; Schwarz, W | 1 |
| Casas-Fernández, C; Domingo-Jiménez, R | 1 |
| Sirven, JI | 1 |
| Lawden, MC | 1 |
| Johnson, MA; Krauss, GL; Miller, NR; Sheth, S | 1 |
| Bauer, J; Bergmann, A; Genton, P; Reuber, M; Stodieck, SR | 1 |
| Danhof, M; Edelbroek, PM; Jonker, DM; Piotrovsky, VK; Vermeij, DA; Voskuyl, RA | 1 |
| Bergin, AM; Connolly, M | 1 |
| Johannessen, SI; Perucca, E | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Danhof, M; Jonker, DM; Voskuyl, RA | 1 |
| Patsalos, PN; Ratnaraj, N; Wang, X | 1 |
| Bolvig, T; Clausen, RP; Falch, E; Frølund, B; Hansen, SL; Krogsgaard-Larsen, P; Larsson, OM; Perregaard, J; Petersen, G; Sarup, A; Schousboe, A; Slough, S; Watson, WP; White, HS | 1 |
| Arroyo, S; Boothman, BR; Brodie, MJ; Calandre, EP; Crawford, PM; Duncan, JS; Duncan, R; Forcadas, I; Nieto, M | 1 |
| Cowley, M; Kilpatrick, C; Kornberg, AJ; Matkovic, Z; O'Brien, TJ; Vinton, A | 1 |
| Elger, CE; Fritz, N; Glogau, S; Helmstaedter, C; Hoffmann, J; Rademacher, M | 1 |
| Kälviäinen, R; Mäntyjärvi, M; Sorri, I | 1 |
| Feuerstein, TJ; Stefan, H | 1 |
| Johannessen, SI; Tomson, T | 1 |
| Czuczwar, SJ; Luszczki, JJ | 1 |
| Bauer, J; Chahem, J | 1 |
| Chapman, AG; Meldrum, BS; Parvez, NS; Smith, SE | 1 |
| Brodie, MJ; Leach, JP | 1 |
| Patsalos, PN; Sander, JW | 1 |
| Anderson, CA; Faingold, CL; Randall, ME | 1 |
| Gram, L | 3 |
| Duncan, JS; Patsalos, PN; Sander, JW; Sveinbjornsdottir, S; Thompson, PJ; Upton, D | 1 |
| Pierce, MW; Shu, VS | 1 |
| Ramsay, RE; Slater, JD | 1 |
| Leppik, IE | 2 |
| Brodie, MJ | 1 |
| Blum, D; Fisher, R | 1 |
| Chadwick, D; Schapel, G | 1 |
| Draguhn, A; Heinemann, U; Meierkord, H; Pfeiffer, M | 1 |
| Chadwick, DW; Kadir, ZA; Marson, AG | 1 |
| Meldrum, BS | 1 |
| Chadwick, DW; Kadir, Z; Marson, T | 1 |
| Bialer, M; Johannessen, SI; Kupferberg, HJ; Levy, RH; Loiseau, P; Perucca, E | 1 |
| Andreasen, M; Fueta, Y; Lambert, JD; Roepstorff, A | 1 |
| Cascino, GD; Graves, NM; Gustavson, LE; Leppik, IE; Pixton, GC; So, EL; Wolff, D | 1 |
| Brodie, MJ; Wilson, EA | 1 |
| Shorvon, S; Stefan, H | 1 |
| Shinnar, S | 1 |
| Bowery, NG; Richards, DA | 1 |
| Dalby, NO; Nielsen, EB | 2 |
| Herranz, JL | 2 |
| Jansen, JA; Larsen, S; Mengel, HB; Richens, A; Snel, S | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Adkins, JC; Noble, S | 1 |
| Cato, A; El-Shourbagy, T; Gustavson, LE; Kelly, EA; Qian, J | 1 |
| Arnett, JL; Dodrill, CB; Lenz, GT; Pixton, GC; Shu, V; Sommerville, KW | 1 |
| Eckardt, KM; Steinhoff, BJ | 1 |
| El-Shourbagy, T; Granneman, GR; Gustavson, LE; Locke, C; Samara, EE; Sommerville, KW | 1 |
| Bourgeois, BF | 1 |
| Luer, MS; Rhoney, DH | 1 |
| Baweja, RK; Mahmood, I; Tammara, VK | 1 |
| Wilner, AN | 1 |
| Deaton, R; Gram, L; Leppik, IE; Sommerville, KW | 1 |
| Ben-Menachem, E; Cramer, JA; Fisher, R; French, J; Mattson, RH | 1 |
| Bowery, NG; Davies, CC; Sutch, RJ | 1 |
| Appleton, R; Pellock, JM | 1 |
| Schachter, SC | 2 |
| Holden, KR; Titus, MO | 1 |
| Brodie, MJ; Butler, E; Sills, GJ; Thompson, GG | 1 |
| Chapman, AG; Meldrum, BS | 1 |
| Perucca, E | 1 |
| Crawford, PM; Datta, PK | 1 |
| Czuczwar, SJ | 1 |
| Popielarczyk, M; Sokołowska, D; Wendorff, J; Zubiel, M | 1 |
| Vajda, FJ | 1 |
| Betts, T; Crawford, PM; Rüsch, N; Trimble, MR | 1 |
| Weitz, R | 1 |
| Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW | 1 |
| Brodie, M; Elger, CE; Gram, L; Kälviäinen, R; Krämer, G; Perucca, E; Schmidt, D | 1 |
| Balslev, T; Buchholt, J; Uldall, P | 1 |
| Aarons, L; Groes, L; Ingwersen, SH; Nielsen, KK; Pedersen, PC | 1 |
| Akman, CI; Schubert, R | 1 |
| Bulteau, C; Dulac, O; Lyby, K; Pedersen, SA; Uldall, P | 1 |
| Foletti, GB | 1 |
| Jedrzejczak, J | 1 |
| Cardile, V; Maci, T; Palumbo, M; Pavone, A; Perciavalle, V; Renis, M | 1 |
| Aldenkamp, AP | 1 |
| Grabowska-Grzyb, A; Wolańczyk, T | 1 |
| Genton, P; Guerrini, R; Perucca, E | 1 |
| Kälviäinen, R | 1 |
| Pedersen, B | 1 |
| Kellinghaus, C; Loddenkemper, T; Lüdemann, P; Weitemeyer, L | 1 |
| Beran, RG | 1 |
| Kaufman, KR; Keyser, BJ; Lepore, FE | 1 |
| Hurkacz, M; Kozik, A; Orzechowska-Juzwenko, K; Unolt, J; Wiela-Hojeńska, A | 1 |
| Bilo, L; Boccella, P; Nocerino, C; Striano, P; Striano, S | 1 |
| Deaton, R; Krauss, G; Sackellares, JC; Sommerville, KW | 1 |
| Morris, GL; Ostrovskiy, D; Spanaki, MV | 1 |
| Gustavson, LE; Mant, T; McKelvy, JF; Mengel, HB; Pierce, MW; Suzdak, PD | 1 |
45 review(s) available for tiagabine and Epilepsy
| Article | Year |
|---|---|
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs.
Topics: Animals; Anticonvulsants; Astrocytes; Epilepsy; GABA Plasma Membrane Transport Proteins; Humans; Neurons; Nipecotic Acids; Synaptic Transmission; Tiagabine | 2017 |
[Tiagabine--own experience in the refractory epilepsy treatment].
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Cognition; Drug Prescriptions; Epilepsy; Humans; Neuroprotective Agents; Nipecotic Acids; Tiagabine; Treatment Outcome | 2013 |
New pharmacotherapies for pediatric seizures.
Topics: Adolescent; Amines; Animals; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Pediatrics; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 2004 |
Behavioral and cognitive effects of anti-epileptic drugs.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Neurotransmitter Agents; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Triazines; Vigabatrin | 2010 |
[Characteristics and indications of tiagabine].
Topics: Animals; Anticonvulsants; Drug Interactions; Epilepsy; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurons; Nipecotic Acids; Tiagabine | 2002 |
Antiepileptic drug therapy for adults: when to initiate and how to choose.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Recurrence; Risk Factors; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2003 |
Novel anticonvulsant drugs.
Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2007 |
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2006 |
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1994 |
Handling seizure data: special problems.
Topics: Anticonvulsants; Clinical Trials as Topic; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Tiagabine; Valproic Acid | 1993 |
Antiepileptic drugs in clinical development.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Structure-Activity Relationship; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
Tiagabine pharmacology in profile.
Topics: Aged; Animals; Anticonvulsants; Biological Availability; Delayed-Action Preparations; Drug Interactions; Epilepsy; gamma-Aminobutyric Acid; Half-Life; Hippocampus; Humans; Kindling, Neurologic; Mice; Nipecotic Acids; Rats; Receptors, GABA; Synaptic Transmission; Tiagabine | 1995 |
Clobazam, oxcarbazepine, tiagabine, topiramate, and other new antiepileptic drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clinical Trials as Topic; Clobazam; Disease Models, Animal; Epilepsy; Fructose; Humans; Nipecotic Acids; Oxcarbazepine; Rats; Tiagabine; Topiramate | 1995 |
New antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1996 |
Pharmacokinetics of new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Cyclohexanecarboxylic Acids; Enzyme Induction; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Update on the mechanism of action of antiepileptic drugs.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Membrane Potentials; Mice; Neurotransmitter Agents; Nipecotic Acids; Phenethylamines; Phenylcarbamates; Propylene Glycols; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Clinical administration of new antiepileptic drugs: an overview of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Odds Ratio; Placebos; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 1996 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Overview of the safety of newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
Tiagabine.
Topics: Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy; Humans; Nipecotic Acids; Tiagabine | 1997 |
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1997 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Tiagabine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of epilepsy.
Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Humans; Mice; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Tiagabine | 1998 |
Role of new and established antiepileptic drugs.
Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Drug Interactions; Epilepsies, Partial; Epilepsy; Felbamate; Fructose; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Teratogens; Tiagabine; Topiramate; Triazines; Vigabatrin | 1998 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Vigabatrin | 1998 |
Tiagabine: a novel antiepileptic drug.
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy; Humans; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Tiagabine | 1998 |
New medication options for patients with epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines | 1998 |
New antiepileptic drugs: comparison of key clinical trials.
Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Placebos; Research Design; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 1999 |
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Spasms, Infantile; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Tiagabine.
Topics: Anticonvulsants; Brain; Brain Chemistry; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Tiagabine; Treatment Outcome | 1999 |
Managing pediatric epilepsy syndromes with new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Basic mechanisms of gabitril (tiagabine) and future potential developments.
Topics: Animals; Anticonvulsants; Bipolar Disorder; Carrier Proteins; Epilepsy; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Kindling, Neurologic; Limbic System; Membrane Proteins; Membrane Transport Proteins; Mice; Nipecotic Acids; Organic Anion Transporters; Pain; Rats; Tiagabine | 1999 |
The clinical pharmacokinetics of the new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide | 1999 |
[GABA-ergic system and antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Binding, Competitive; Calcium Channels; Chloride Channels; Cyclohexanecarboxylic Acids; Epilepsy; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Nipecotic Acids; Receptors, GABA; Sodium Channels; Tiagabine; Vigabatrin | 2000 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
[Current data on tiagabine].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Drug Tolerance; Epilepsy; Humans; Middle Aged; Nipecotic Acids; Receptors, GABA; Tiagabine | 2000 |
[Tiagabine--a new antiepileptic drug].
Topics: Anticonvulsants; Epilepsy; Humans; Nipecotic Acids; Tiagabine | 1998 |
Tiagabine in the treatment of epilepsy--a clinical review with a guide for the prescribing physician.
Topics: Adult; Anticonvulsants; Drug Prescriptions; Epilepsy; Humans; Nipecotic Acids; Tiagabine | 2000 |
[Evaluation of tiagabine efficacy in different groups of patients with epilepsy].
Topics: Adult; Aged; Anticonvulsants; Child; Controlled Clinical Trials as Topic; Drug Interactions; Epilepsy; Female; Humans; Mental Disorders; Nipecotic Acids; Pregnancy; Pregnancy Complications; Quality of Life; Tiagabine | 2000 |
Pharmacology and clinical experience with tiagabine.
Topics: Biological Availability; Cross-Over Studies; Double-Blind Method; Epilepsy; GABA Agonists; Humans; Multicenter Studies as Topic; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine | 2001 |
Tiagabine in clinical practice.
Topics: Anticonvulsants; Confusion; Drug Administration Schedule; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Humans; Nipecotic Acids; Practice Guidelines as Topic; Tiagabine; Treatment Outcome | 2001 |
Tiagabine.
Topics: Animals; Anticonvulsants; Brain; Drugs, Investigational; Electroencephalography; Epilepsy; Evoked Potentials; Humans; Mice; Nipecotic Acids; Rats; Tiagabine | 1991 |
18 trial(s) available for tiagabine and Epilepsy
| Article | Year |
|---|---|
Tiagabine in clinical practice: effects on seizure control and behavior.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Behavioral Symptoms; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nipecotic Acids; Tiagabine; Time Factors; Treatment Outcome; Young Adult | 2013 |
A controlled study comparing visual function in patients treated with vigabatrin and tiagabine.
Topics: Adult; Aged; Anticonvulsants; Cross-Sectional Studies; Electroretinography; Epilepsy; Female; Humans; Male; Middle Aged; Nipecotic Acids; Tiagabine; Vigabatrin; Visual Acuity; Visual Fields | 2003 |
Tolerability of tiagabine: a prospective open-label study.
Topics: Adult; Anticonvulsants; Cognition Disorders; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Mental Disorders; Middle Aged; Nipecotic Acids; Prospective Studies; Status Epilepticus; Tiagabine | 2002 |
A randomised open-label study of tiagabine given two or three times daily in refractory epilepsy.
Topics: Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Tolerance; Epilepsy; Female; Humans; Male; Nipecotic Acids; Tiagabine | 2005 |
Efficacy and cognitive side effects of tiagabine and topiramate in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Cognition Disorders; Drug Evaluation; Epilepsy; Female; Fructose; Humans; Intelligence; Male; Memory, Short-Term; Middle Aged; Mood Disorders; Neuropsychological Tests; Nipecotic Acids; Tiagabine; Topiramate; Treatment Outcome; Verbal Behavior | 2005 |
Color vision and contrast sensitivity in epilepsy patients treated with initial tiagabine monotherapy.
Topics: Adult; Aged; Anticonvulsants; Color Perception; Contrast Sensitivity; Cross-Sectional Studies; Epilepsy; Female; Functional Laterality; Humans; Male; Middle Aged; Nipecotic Acids; Tiagabine; Vision Tests | 2005 |
Neuropsychological effects of tiagabine, a potential new antiepileptic drug.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Nipecotic Acids; Tiagabine | 1994 |
Tiagabine: the safety landscape.
Topics: Adolescent; Aged; Anticonvulsants; Child; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsy; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Placebos; Proportional Hazards Models; Tiagabine; Treatment Outcome | 1995 |
Pharmacokinetics of tiagabine as add-on therapy in patients taking enzyme-inducing antiepilepsy drugs.
Topics: Adolescent; Adult; Analysis of Variance; Anticonvulsants; Circadian Rhythm; Enzyme Induction; Epilepsy; Female; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Middle Aged; Nipecotic Acids; Tiagabine | 1995 |
[Tiagabine: a GABA-ergic anti-epileptic drug].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Double-Blind Method; Drug Tolerance; Epilepsy; gamma-Aminobutyric Acid; Humans; Middle Aged; Nipecotic Acids; Receptors, GABA; Synapses; Tiagabine | 1997 |
The pharmacokinetics of tiagabine in healthy elderly volunteers and elderly patients with epilepsy.
Topics: Adult; Age Factors; Aged; Anticonvulsants; Epilepsy; Female; Humans; Male; Middle Aged; Nipecotic Acids; Sex Factors; Tiagabine | 1997 |
Effect of renal impairment on the pharmacokinetics and tolerability of tiagabine.
Topics: Adult; Anticonvulsants; Blood Proteins; Chromatography, High Pressure Liquid; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Nipecotic Acids; Protein Binding; Tiagabine; Ultrafiltration | 1998 |
Effects of tiagabine monotherapy on abilities, adjustment, and mood.
Topics: Adolescent; Adult; Affect; Anticonvulsants; Brief Psychiatric Rating Scale; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsy; Female; Humans; Male; Neuropsychological Tests; Nipecotic Acids; Personality Inventory; Psychomotor Performance; Quality of Life; Social Adjustment; Tiagabine; Treatment Outcome | 1998 |
Population analysis of the pharmacokinetics of tiagabine in patients with epilepsy.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Biological Availability; Body Weight; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Liver; Male; Middle Aged; Models, Statistical; Nipecotic Acids; Regression Analysis; Retrospective Studies; Sex Factors; Smoking; Tiagabine | 1998 |
Does percent reduction in seizure frequency correlate with plasma concentration of anticonvulsant drugs? Experience with four anticonvulsant drugs.
Topics: Anticonvulsants; Double-Blind Method; Epilepsy; Flunarizine; Fructose; Humans; Lamotrigine; Linear Models; Logistic Models; Nipecotic Acids; Tiagabine; Topiramate; Triazines | 1998 |
The effect of tiagabine on spasticity in children with intractable epilepsy: a pilot study.
Topics: Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; GABA Antagonists; Humans; Infant; Male; Muscle Spasticity; Nipecotic Acids; Pilot Projects; Quadriplegia; Recovery of Function; Tiagabine; Treatment Outcome | 1999 |
Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin.
Topics: Anticonvulsants; Body Weight; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Nipecotic Acids; Phenytoin; Tiagabine; Weight Gain | 2000 |
Population pharmacokinetics of tiagabine in epileptic patients on monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Middle Aged; Nipecotic Acids; Regression Analysis; Retrospective Studies; Tiagabine | 2000 |
55 other study(ies) available for tiagabine and Epilepsy
| Article | Year |
|---|---|
Tiagabine suppresses pentylenetetrazole-induced seizures in mice and improves behavioral and cognitive parameters by modulating BDNF/TrkB expression and neuroinflammatory markers.
Topics: Animals; Anticonvulsants; Brain-Derived Neurotrophic Factor; Cognition; Epilepsy; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; RNA, Messenger; Seizures; Tiagabine | 2023 |
Antiepileptic Drug Tiagabine Does Not Directly Target Key Cardiac Ion Channels Kv11.1, Nav1.5 and Cav1.2.
Topics: Action Potentials; Animals; Anticonvulsants; Calcium Channels, L-Type; Computer Simulation; Epilepsy; ERG1 Potassium Channel; Heart; Humans; Male; Molecular Docking Simulation; NAV1.5 Voltage-Gated Sodium Channel; Rats; Rats, Wistar; Tiagabine | 2021 |
Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Disease Models, Animal; Drosophila; Drug Design; Epilepsy; Female; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Male; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naphthalenes; Nipecotic Acids; Tiagabine | 2018 |
Tiagabine-induced stupor in patients with psychogenic nonepileptic seizures: nonconvulsive status epilepticus or encephalopathy?
Topics: Adult; Anticonvulsants; Brain Waves; Conversion Disorder; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Neurotoxicity Syndromes; Nipecotic Acids; Status Epilepticus; Stupor; Tiagabine; Video Recording | 2013 |
GABAergic tonic inhibition is regulated by developmental age and epilepsy in the dentate gyrus.
Topics: Aging; Animals; Anticonvulsants; Data Interpretation, Statistical; Dentate Gyrus; Diazepam; Electrophysiological Phenomena; Epilepsy; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Patch-Clamp Techniques; Rats; Rats, Wistar; Status Epilepticus; Tiagabine | 2013 |
Retention rates of new antiepileptic drugs in localization-related epilepsy: a single-center study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Finland; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Levetiracetam; Licensure, Pharmacy; Male; Middle Aged; Nipecotic Acids; Piracetam; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Young Adult | 2009 |
Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves.
Topics: Animals; Anticonvulsants; Brain Chemistry; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Random Allocation; Seizures; Tiagabine; Valproic Acid | 2009 |
Selective suppression of hippocampal region hyperexcitability related to seizure susceptibility in epileptic El mice by the GABA-transporter inhibitor tiagabine.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Electrophysiology; Epilepsy; Female; GABA Agonists; Hippocampus; Male; Mice; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Seizures; Tiagabine | 2002 |
Vigabatrin, tiagabine, and visual fields.
Topics: Anticonvulsants; Epilepsy; Humans; Nipecotic Acids; Retina; Tiagabine; Time Factors; Vigabatrin; Visual Fields | 2003 |
Pharmacodynamic analysis of the interaction between tiagabine and midazolam with an allosteric model that incorporates signal transduction.
Topics: Allosteric Regulation; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Epilepsy; GABA Modulators; Male; Mathematics; Midazolam; Models, Biological; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Tiagabine | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroencephalography; Electroshock; Epilepsy; Humans; Lamotrigine; Male; Nipecotic Acids; Rats; Rats, Wistar; Seizures; Tiagabine; Triazines | 2004 |
The pharmacokinetic inter-relationship of tiagabine in blood, cerebrospinal fluid and brain extracellular fluid (frontal cortex and hippocampus).
Topics: Animals; Anticonvulsants; Epilepsy; Extracellular Fluid; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Microdialysis; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine | 2004 |
First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.
Topics: Acoustic Stimulation; Acyltransferases; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cells, Cultured; Cloning, Molecular; Convulsants; Drug Synergism; Epilepsy; Epilepsy, Reflex; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; N-Acetylglucosaminyltransferases; Neurons; Nipecotic Acids; Pentylenetetrazole; Pilocarpine; Psychomotor Disorders; Recombinant Proteins; Seizures; Tiagabine | 2005 |
Tiagabine-induced generalised non convulsive status epilepticus in patients with lesional focal epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Clonazepam; Electroencephalography; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Nipecotic Acids; Status Epilepticus; Tiagabine | 2005 |
Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Reaction Time; Statistics as Topic; Tiagabine; Vigabatrin | 2007 |
[Treatment of epilepsy with third-line antiepileptic drugs: felbamate, tiagabine, and sulthiame].
Topics: Adult; Anticonvulsants; Epilepsy; Felbamate; Humans; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Retrospective Studies; Thiazines; Tiagabine; Treatment Outcome | 2007 |
The gamma-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Epilepsy; Female; GABA Agents; Male; Motor Activity; Myoclonus; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Oximes; Papio; Photic Stimulation; Proline; Rats; Rats, Inbred Strains; Tiagabine | 1995 |
Synergism with GABAergic drugs in refractory epilepsy.
Topics: 4-Aminobutyrate Transaminase; Adult; Drug Synergism; Epilepsy; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nipecotic Acids; Tiagabine; Vigabatrin | 1994 |
Blockade of GABA uptake with tiagabine inhibits audiogenic seizures and reduces neuronal firing in the inferior colliculus of the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Animals; Brain Mapping; Dose-Response Relationship, Drug; Epilepsy; Female; GABA Antagonists; Inferior Colliculi; Male; Microinjections; Neurons; Nipecotic Acids; Rats; Rats, Mutant Strains; Seizures; Tiagabine; Time Factors | 1994 |
Tiagabine: a novel drug with a GABAergic mechanism of action.
Topics: Animals; Anticonvulsants; Drug Design; Drugs, Investigational; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Prodrugs; Randomized Controlled Trials as Topic; Research Design; Synaptic Transmission; Tiagabine | 1994 |
Tiagabine: The Art of Epilepsy Care. Proceedings of a satellite symposium to the 21st International Epilepsy Congress. Sydney, Australia, September 2, 1995.
Topics: Animals; Anticonvulsants; Epilepsy; Humans; Nipecotic Acids; Tiagabine | 1995 |
Epilepsy care: image of the future.
Topics: Anticonvulsants; Drug Therapy, Combination; Drugs, Investigational; Epilepsy; Forecasting; GABA Agents; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Tiagabine | 1995 |
Tiagabine and non-convulsive status epilepticus.
Topics: Adult; Anticonvulsants; Epilepsy; Humans; Male; Middle Aged; Nipecotic Acids; Tiagabine | 1996 |
Effects of gamma-aminobutyric acid (GABA) agonists and GABA uptake inhibitors on pharmacosensitive and pharmacoresistant epileptiform activity in vitro.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Entorhinal Cortex; Epilepsy; Female; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Muscimol; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Wistar; Tiagabine | 1996 |
Progress report on new antiepileptic drugs: a summary of the Third Eilat Conference.
Topics: Acetamides; Animals; Anticonvulsants; Azetidines; Carbamates; Drug Evaluation, Preclinical; Drugs, Investigational; Epilepsy; Humans; Israel; Levetiracetam; Nipecotic Acids; Phenylenediamines; Piracetam; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Thiazoles; Tiagabine; Triazoles | 1996 |
Analysis of the kinetics of synaptic inhibition points to a reduction in GABA release in area CA1 of the genetically epileptic mouse, El.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Mice; Mice, Mutant Strains; Neural Inhibition; Nipecotic Acids; Receptors, GABA; Species Specificity; Synaptic Transmission; Tiagabine | 1996 |
Comparative effects of the GABA uptake inhibitors, tiagabine and NNC-711, on extracellular GABA levels in the rat ventrolateral thalamus.
Topics: Analysis of Variance; Animals; Anticonvulsants; Basal Metabolism; Drug Evaluation, Preclinical; Epilepsy; gamma-Aminobutyric Acid; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Rats; Rats, Wistar; Thalamus; Tiagabine | 1996 |
Tiagabine exerts an anti-epileptogenic effect in amygdala kindling epileptogenesis in the rat.
Topics: Amygdala; Animals; Anticonvulsants; Epilepsy; Kindling, Neurologic; Male; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine | 1997 |
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Mice; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine; Triazines; Vigabatrin | 1997 |
Antiepileptic approved for adjunctive therapy.
Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aged; Anticonvulsants; Child; Epilepsy; Humans; Middle Aged; Nipecotic Acids; Seizures; Tiagabine; United States; United States Food and Drug Administration | 1998 |
Nonconvulsive status epilepticus in two patients receiving tiagabine treatment.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Female; Humans; Nipecotic Acids; Status Epilepticus; Tiagabine | 1998 |
Safety of tiagabine: summary of 53 trials.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Overdose; Epilepsy; Female; Humans; Incidence; Longitudinal Studies; Male; Middle Aged; Neoplasms; Nervous System; Nipecotic Acids; Osmolar Concentration; Pregnancy; Safety; Tiagabine | 1999 |
GABA release and uptake measured in crude synaptosomes from Genetic Absence Epilepsy Rats from Strasbourg (GAERS).
Topics: Aminooxyacetic Acid; Animals; Autoradiography; beta-Alanine; Cerebral Cortex; Epilepsy; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Nipecotic Acids; Oximes; Rats; Rats, Mutant Strains; Synaptosomes; Thalamus; Tiagabine; Tritium | 1999 |
Vigabatrin and tiagabine are pharmacologically different drugs. A pre-clinical study.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Evaluation Studies as Topic; Male; Mice; Mice, Inbred Strains; Nipecotic Acids; Tiagabine; Vigabatrin | 1999 |
Refractory epilepsy: treatment with new antiepileptic drugs.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Patient Dropouts; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
[Tiagabine in drug-resistant epilepsy in children: preliminary study].
Topics: Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Humans; Male; Nipecotic Acids; Tiagabine; Treatment Outcome | 2000 |
Psychiatric symptoms after therapy with new antiepileptic drugs: psychopathological and seizure related variables.
Topics: Adolescent; Adult; Anticonvulsants; Dominance, Cerebral; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Mood Disorders; Nipecotic Acids; Psychoses, Substance-Induced; Recurrence; Retrospective Studies; Tiagabine; Topiramate; United Kingdom; Vigabatrin | 2000 |
Provocation of non-convulsive status epilepticus by tiagabine in three adolescent patients.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy; Female; GABA Agonists; Humans; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Status Epilepticus; Tiagabine | 2000 |
The role of tiagabine in the treatment of intractable epilepsy of childhood with multifocal independent spikes: a case report.
Topics: Anticonvulsants; Brain; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Nipecotic Acids; Tiagabine; Valproic Acid | 2000 |
Tiagabine adjunctive therapy in children with refractory epilepsy: a single-blind dose escalating study.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy; Female; Humans; Male; Nipecotic Acids; Prospective Studies; Single-Blind Method; Tiagabine | 2000 |
[Clinical utilization of new anti-epileptic agents].
Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Visual Fields | 2000 |
Tiagabine treatment and DNA damage in rat astrocytes: an in vitro study by comet assay.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Epilepsy; GABA Agonists; Genome; Glial Fibrillary Acidic Protein; Nerve Degeneration; Nipecotic Acids; Rats; Tiagabine | 2001 |
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin | 2001 |
Transient dystonias in three patients treated with tiagabine.
Topics: Acute Disease; Adult; Anticonvulsants; Basal Ganglia Diseases; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dystonia; Epilepsy; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Female; Humans; Male; Nipecotic Acids; Tiagabine | 2001 |
Long-term safety of tiagabine.
Topics: Anticonvulsants; Clinical Trials as Topic; Cognition; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Humans; Nipecotic Acids; Psychoses, Substance-Induced; Tiagabine; Treatment Outcome; Vision Disorders; Visual Fields | 2001 |
Tiagabine (gabitril) experience in children.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Europe; Humans; Infant; Nipecotic Acids; Placebos; Tiagabine; Treatment Outcome; United States | 2001 |
Epilepsy in the elderly: the use of tiagabine.
Topics: Age Factors; Aged; Anticonvulsants; Clinical Trials as Topic; Drug Administration Schedule; Drug Approval; Epilepsy; Humans; Middle Aged; Nipecotic Acids; Tiagabine; United States | 2001 |
[Experience with tiagabine in the clinical practice; new insights as to the efficacy and safety profile].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Nipecotic Acids; Outpatients; Patient Compliance; Retrospective Studies; Status Epilepticus; Survival Analysis; Tiagabine; Treatment Outcome | 2001 |
Ethical dilemmas of potential adverse events.
Topics: Anticonvulsants; Epilepsy; Ethics, Medical; GABA Agonists; Humans; Informed Consent; Liability, Legal; Nipecotic Acids; Tiagabine; Vigabatrin; Vision Disorders | 2001 |
Visual fields and tiagabine: a quandary.
Topics: Adult; Anticonvulsants; Epilepsy; Humans; Male; Nipecotic Acids; Severity of Illness Index; Tiagabine; Vision Disorders; Visual Fields | 2001 |
[Monitoring of renal function in epileptic children and teenagers treated with valproic acid or carbamazepine in concomitant therapy with tiagabine].
Topics: Acetylglucosaminidase; Adolescent; Adult; Anticonvulsants; beta 2-Microglobulin; Carbamazepine; Case-Control Studies; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Kidney; Kidney Function Tests; Kidney Glomerulus; Kidney Tubules; Male; Nipecotic Acids; Renal Insufficiency; Statistics, Nonparametric; Tiagabine; Time Factors; Valproic Acid | 2001 |
Tiagabine in glial tumors.
Topics: Adolescent; Adult; Anticonvulsants; Astrocytoma; Child; Drug Therapy, Combination; Epilepsy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nipecotic Acids; Oligodendroglioma; Tiagabine | 2002 |
Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment.
Topics: Adolescent; Adult; Aged; Child; Double-Blind Method; Epilepsy; Female; GABA Agonists; Hallucinations; Humans; Incidence; Male; Medical Records; Middle Aged; Multicenter Studies as Topic; Nipecotic Acids; Placebos; Randomized Controlled Trials as Topic; Tiagabine | 2002 |
Tiagabine overdose can induce convulsive status epilepticus.
Topics: Adult; Dose-Response Relationship, Drug; Drug Overdose; Epilepsy; Humans; Male; Nipecotic Acids; Status Epilepticus; Suicide, Attempted; Tiagabine | 2002 |