tiagabine has been researched along with Disease Models, Animal in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 14 (41.18) | 29.6817 |
| 2010's | 11 (32.35) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Chuang, SH; Reddy, DS | 1 |
| Bulaj, KK; Grussendorf, E; Grussendorf, J; Handy, LJ; Hunt, M; Krumin, RK; Pruess, TH; Smith, MD; Vanegas, F; White, K; Wilcox, KS; Woodhead, JH | 1 |
| Celani, MVB; Dos Santos, WF; Gobbo-Neto, L; Godoy, LD; Liberato, JL; Lopes, NP | 1 |
| Andres-Mach, M; Chmielewski, J; Florek-Luszczki, M; Kondrat-Wrobel, MW; Luszczki, JJ; Patrzylas, P; Szpringer, M; Zagaja, M; Zaluska, K | 1 |
| Dunn, R; Forcelli, PA; Pak, DTS; Queenan, BN | 1 |
| Choubey, PK; Seth, A; Sharma, PA; Shrivastava, SK; Srivastava, P; Tripathi, A; Tripathi, PN | 1 |
| Nieoczym, D; Socała, K; Szafarz, M; Wlaź, P; Wyska, E | 1 |
| Amador-Arjona, A; D'Amico, D; Dierssen, M; Santos, M; Spadoni, O; Stork, O | 1 |
| Cull-Candy, SG; Dupree, JL; Edwards, J; Farrant, M; Gallo, V; Harvey, L; Hübner, CA; Li, P; McEllin, B; Scafidi, J; Sun, D; Zonouzi, M | 1 |
| Dziubina, A; Filipek, B; Kowalczyk, P; Kulig, K; Librowski, T; Podkowa, A; Sałat, K | 1 |
| Bai, X; Fei, J; Huang, D; Huang, F; Huang, L; Liu, J; Ma, Y; Suo, H; Tong, J; Wang, P; Wang, Z; Xu, J; Yang, Y; Yu, M | 1 |
| Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sielski, M | 1 |
| Marsh, AD; Marsh, DR; Meisner, JG | 1 |
| Draguhn, A; Frahm, C; Stief, F; Zuschratter, W | 1 |
| Danhof, M; Jonker, DM; Voskuyl, RA | 1 |
| Fueta, Y; Kunugita, N; Schwarz, W | 1 |
| Czuczwar, SJ; Luszczki, JJ | 2 |
| Tolmacheva, EA; van Luijtelaar, G | 1 |
| Borowicz, KK; Czuczwar, SJ; Luszczki, JJ; Zadrozniak, M | 1 |
| Akula, KK; Dhir, A; Kulkarni, SK | 1 |
| Clausen, RP; Frølund, B; Krogsgaard-Larsen, P; Larsson, OM; Saunders, GW; Schousboe, A; Smith, MD; White, HS; Wilcox, KS | 1 |
| Duan, W; Jiang, M; Li, Q; Liang, Y; Masuda, N; Peng, Q; Ross, CA; Wang, W; Wang, X; Zhao, M | 1 |
| Blezer, EH; Coenen, AM; van Luijtelaar, EL | 1 |
| Friedman, MB; Gao, XM; Kakigi, T; Tamminga, CA | 1 |
| Blum, D; Fisher, R | 1 |
| Andreasen, M; Fueta, Y; Lambert, JD; Roepstorff, A | 1 |
| Hosford, DA; Wang, Y | 1 |
| Dalby, NO; Nielsen, EB | 1 |
| White, HS | 1 |
| Brodie, MJ; Butler, E; Sills, GJ; Thompson, GG | 1 |
| Jeerakathil, T; Li, Q; Shuaib, A; Wang, CX; Yang, Y | 1 |
| Haugvicová, R; Kubová, H; Mares, P; Skutová, M; Suchomelová, L | 1 |
| Bauer, CA; Brozoski, TJ | 1 |
2 review(s) available for tiagabine and Disease Models, Animal
| Article | Year |
|---|---|
Clobazam, oxcarbazepine, tiagabine, topiramate, and other new antiepileptic drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clinical Trials as Topic; Clobazam; Disease Models, Animal; Epilepsy; Fructose; Humans; Nipecotic Acids; Oxcarbazepine; Rats; Tiagabine; Topiramate | 1995 |
Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsies, Partial; Felbamate; Fructose; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Receptors, GABA; Sodium Channels; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1999 |
32 other study(ies) available for tiagabine and Disease Models, Animal
| Article | Year |
|---|---|
Isobolographic Analysis of Antiseizure Activity of the GABA Type A Receptor-Modulating Synthetic Neurosteroids Brexanolone and Ganaxolone with Tiagabine and Midazolam.
Topics: Animals; Anticonvulsants; beta-Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Midazolam; Neurosteroids; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Seizures; Tiagabine | 2020 |
Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain.
Topics: Analgesics; Animals; Anticonvulsants; Antidepressive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Neuralgia; Nipecotic Acids; Pain Measurement; Rats; Rats, Sprague-Dawley; Rodentia; Tiagabine | 2017 |
Disease Modifying Effects of the Spider Toxin Parawixin2 in the Experimental Epilepsy Model.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Male; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Pilocarpine; Rats, Wistar; Spider Venoms; Tiagabine; Urea | 2017 |
Effects of arachidonyl-2'-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice.
Topics: Acetamides; Animals; Anticonvulsants; Arachidonic Acids; Avoidance Learning; Benzodiazepines; Clobazam; Cornea; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy, Complex Partial; Lacosamide; Levetiracetam; Male; Mice; Muscle Strength; Nipecotic Acids; Phenobarbital; Phenylmethylsulfonyl Fluoride; Piracetam; Psychomotor Performance; Receptor, Cannabinoid, CB1; Tiagabine; Valproic Acid | 2017 |
Divergent effects of levetiracetam and tiagabine against spontaneous seizures in adult rats following neonatal hypoxia.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Hypoxia; Levetiracetam; Male; Phenobarbital; Prohibitins; Rats, Long-Evans; Seizures; Tiagabine | 2018 |
Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Disease Models, Animal; Drosophila; Drug Design; Epilepsy; Female; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Male; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naphthalenes; Nipecotic Acids; Tiagabine | 2018 |
Acute effect of cannabidiol on the activity of various novel antiepileptic drugs in the maximal electroshock- and 6 Hz-induced seizures in mice: Pharmacodynamic and pharmacokinetic studies.
Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Drug Resistant Epilepsy; Electric Stimulation; Gabapentin; Lacosamide; Lamotrigine; Levetiracetam; Male; Mice; Oxcarbazepine; Pregabalin; Seizures; Tiagabine; Topiramate | 2019 |
Hippocampal hyperexcitability underlies enhanced fear memories in TgNTRK3, a panic disorder mouse model.
Topics: Analysis of Variance; Animals; Bacterial Proteins; Conditioning, Classical; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Exploratory Behavior; Extinction, Psychological; Fear; GABA Agonists; Generalization, Psychological; Glutamate Decarboxylase; Guanylate Kinases; Hippocampus; Luminescent Proteins; Maze Learning; Membrane Proteins; Memory; Mice; Mice, Transgenic; Nipecotic Acids; Panic Disorder; Piperidines; Proto-Oncogene Proteins c-fos; Receptor, trkC; Tiagabine; Vesicular Glutamate Transport Proteins | 2013 |
GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury.
Topics: Action Potentials; Animals; Animals, Newborn; Asphyxia Neonatorum; Carbachol; Cell Count; Cells, Cultured; Cerebellum; Demyelinating Diseases; Disease Models, Animal; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypoxia, Brain; Interneurons; Male; Mice; Mice, Knockout; Mice, Transgenic; Neural Stem Cells; Neurogenesis; Nipecotic Acids; Oligodendroglia; Purkinje Cells; Receptors, GABA-A; Solute Carrier Family 12, Member 2; Tiagabine; Vigabatrin; White Matter | 2015 |
Anticonvulsant active inhibitor of GABA transporter subtype 1, tiagabine, with activity in mouse models of anxiety, pain and depression.
Topics: Animals; Anticonvulsants; Anxiety; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Male; Mice; Nipecotic Acids; Pain; Seizures; Tiagabine | 2015 |
Tiagabine Protects Dopaminergic Neurons against Neurotoxins by Inhibiting Microglial Activation.
Topics: Animals; Baclofen; Cell Line, Tumor; Disease Models, Animal; Dopaminergic Neurons; GABA Plasma Membrane Transport Proteins; Inflammation Mediators; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; MPTP Poisoning; Muscimol; Neuroprotective Agents; Neurotoxins; NF-kappa B; Nipecotic Acids; Tiagabine | 2015 |
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin | 2009 |
Loss of GABAergic interneurons in laminae I-III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury.
Topics: Animals; Apoptosis; Caspase 3; Cell Count; Disease Models, Animal; Down-Regulation; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Interneurons; Male; Mice; Mice, Transgenic; Nerve Degeneration; Neural Inhibition; Neuralgia; Nipecotic Acids; Pain Measurement; Pain Threshold; Posterior Horn Cells; Promoter Regions, Genetic; Spinal Cord Injuries; Tiagabine | 2010 |
Unaltered control of extracellular GABA-concentration through GAT-1 in the hippocampus of rats after pilocarpine-induced status epilepticus.
Topics: Animals; Disease Models, Animal; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Muscarinic Agonists; Nipecotic Acids; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Tiagabine | 2003 |
Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroencephalography; Electroshock; Epilepsy; Humans; Lamotrigine; Male; Nipecotic Acids; Rats; Rats, Wistar; Seizures; Tiagabine; Triazines | 2004 |
Antiepileptic action induced by a combination of vigabatrin and tiagabine.
Topics: Action Potentials; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Mice; Nipecotic Acids; Oocytes; Patch-Clamp Techniques; Potassium Chloride; Seizures; Tiagabine; Time Factors; Vigabatrin; Xenopus laevis | 2005 |
Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.
Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Nipecotic Acids; Oxcarbazepine; Pentylenetetrazole; Seizures; Tiagabine | 2005 |
Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Reaction Time; Statistics as Topic; Tiagabine; Vigabatrin | 2007 |
Absence seizures are reduced by the enhancement of GABA-ergic inhibition in the hippocampus in WAG/Rij rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy, Absence; gamma-Aminobutyric Acid; Hippocampus; Male; Microinjections; Neural Inhibition; Nipecotic Acids; Progesterone; Rats; Rats, Inbred Strains; Synaptic Transmission; Tiagabine | 2007 |
Interactions between tiagabine and conventional antiepileptic drugs in the rat model of complex partial seizures.
Topics: Amygdala; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsies, Partial; Male; Nipecotic Acids; Rats; Rats, Wistar; Severity of Illness Index; Tiagabine | 2008 |
Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; Glutathione; Huntington Disease; Lipid Peroxidation; Male; Memory Disorders; Motor Activity; Nipecotic Acids; Nitro Compounds; Nitroprusside; Propionates; Rats; Rats, Wistar; RNA; Rotarod Performance Test; Tiagabine | 2008 |
Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC).
Topics: Animals; Carrier Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Evoked Potentials; GABA Agonists; GABA Plasma Membrane Transport Proteins; In Vitro Techniques; Isoxazoles; Kainic Acid; Male; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tiagabine | 2008 |
Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.
Topics: Animals; Arginine; Asparagine; Disease Models, Animal; Female; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Mice, Transgenic; Neuroprotective Agents; Nipecotic Acids; PC12 Cells; Rats; Tiagabine | 2008 |
Effects of the GABA-uptake inhibitor tiagabine on electroencephalogram, spike-wave discharges and behaviour of rats.
Topics: Action Potentials; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Electroencephalography; Epilepsy, Generalized; gamma-Aminobutyric Acid; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Rats; Rats, Inbred Strains; Tiagabine | 1995 |
Tiagabine inhibits haloperidol-induced oral dyskinesias in rats.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Haloperidol; Male; Mastication; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Single-Blind Method; Tiagabine | 1994 |
Analysis of the kinetics of synaptic inhibition points to a reduction in GABA release in area CA1 of the genetically epileptic mouse, El.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Mice; Mice, Mutant Strains; Neural Inhibition; Nipecotic Acids; Receptors, GABA; Species Specificity; Synaptic Transmission; Tiagabine | 1996 |
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Mice; Nipecotic Acids; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Mice; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine; Triazines; Vigabatrin | 1997 |
Vigabatrin and tiagabine are pharmacologically different drugs. A pre-clinical study.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Evaluation Studies as Topic; Male; Mice; Mice, Inbred Strains; Nipecotic Acids; Tiagabine; Vigabatrin | 1999 |
Dose-dependent neuroprotection with tiagabine in a focal cerebral ischemia model in rat.
Topics: Animals; Brain; Cerebral Infarction; Disease Models, Animal; GABA Agonists; Intracranial Embolism; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Neuroprotective Agents; Nipecotic Acids; Rats; Rats, Wistar; Tiagabine | 2000 |
Two different anticonvulsant actions of tiagabine in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Tiagabine | 2000 |
Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Deafness; Diagnosis, Differential; Disease Models, Animal; Ear; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Noise; Pitch Perception; Psychophysics; Rats; Rats, Long-Evans; Tiagabine; Tinnitus; Wounds and Injuries | 2001 |