Page last updated: 2024-11-06

thyroxine and Vitiligo

thyroxine has been researched along with Vitiligo in 13 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.

Research Excerpts

ExcerptRelevanceReference
"Topical tacrolimus was recently introduced as a novel therapeutic option in vitiligo."9.13Occlusive treatment enhances efficacy of tacrolimus 0.1% ointment in adult patients with vitiligo: results of a placebo-controlled 12-month prospective study. ( Bröcker, EB; Hamm, H; Hartmann, A, 2008)
"Topical tacrolimus was recently introduced as a novel therapeutic option in vitiligo."5.13Occlusive treatment enhances efficacy of tacrolimus 0.1% ointment in adult patients with vitiligo: results of a placebo-controlled 12-month prospective study. ( Bröcker, EB; Hamm, H; Hartmann, A, 2008)
"The two autoimmune diseases are not only linked by a concordance of clinical presentations and an autoimmune/oxidative stress-mediated toxicity pathogenesis but also by an apparent biochemical commonality."1.51Vitiligo and Hashimoto's thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis. ( Bellanti, JA; Calderone, R; Li, D; Liang, G, 2019)
"The prevalence of halo nevi was significantly higher (P < 0."1.46Effects of age of onset on disease characteristics in non-segmental vitiligo. ( Cosansu, NC; Dikicier, BS; Erdem, T; Solak, B, 2017)
"Vitiligo is considered to be an autoimmune disease and is known to be associated with other autoimmune diseases, particularly affecting the thyroid."1.39High prevalence of autoimmune thyroiditis in children and adolescents with vitiligo. ( Bos, JD; Chandeck, C; Geskus, RB; Kroon, MW; Luiten, RM; van der Veen, JP; van Trotsenburg, P; Vrijman, C; Wind, BS; Wolkerstorfer, A, 2013)
"Vitiligo is the most common pigmentation-related disorder worldwide."1.37Relevance of autoimmune thyroiditis in children and adolescents with vitiligo. ( Alpay, K; Bahadır, S; Okten, A; Uncu, S; Yaylı, S, 2011)
"The hydroxychloroquine dose was tapered to 200 mg daily after 12 months, then to 100 mg daily after 18 months therapy."1.33Connective tissue panniculitis in a child with vitiligo and Hashimoto's thyroiditis. ( Mirza, B; Muir, J; Peake, J; Whitehead, K, 2006)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, D1
Liang, G1
Calderone, R1
Bellanti, JA1
Kroon, MW1
Vrijman, C1
Chandeck, C1
Wind, BS1
Wolkerstorfer, A1
Luiten, RM1
Bos, JD1
Geskus, RB1
van Trotsenburg, P1
van der Veen, JP1
Xianfeng, C1
Yuegen, J1
Zhiyu, Y1
Yan, Y1
Xuesi, Z1
Fenglai, W1
Ansheng, L1
Wei, W1
Solak, B1
Dikicier, BS1
Cosansu, NC1
Erdem, T1
Keskin, M1
Savaş-Erdeve, Ş1
Özbay-Hoşnut, F1
Kurnaz, E1
Çetinkaya, S1
Aycan, Z1
Hartmann, A1
Bröcker, EB1
Hamm, H1
Uncu, S1
Yaylı, S1
Bahadır, S1
Okten, A1
Alpay, K1
Basaria, S1
de Beur, SJ1
DEMOWBRAY, RR1
Dervis, E1
Acbay, O1
Barut, G1
Karaoglu, A1
Ersoy, L1
Mirza, B1
Muir, J1
Peake, J1
Whitehead, K1
Pal, SK1
Ghosh, KK1
Banerjee, PK1
Frati, R1
Frati, C1
Sassano, PP1
Antonaci, A1

Trials

1 trial available for thyroxine and Vitiligo

ArticleYear
Occlusive treatment enhances efficacy of tacrolimus 0.1% ointment in adult patients with vitiligo: results of a placebo-controlled 12-month prospective study.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:5

    Topics: Adult; Antibodies; Antibodies, Antinuclear; Female; Humans; Immunoglobulin E; Immunosuppressive Agen

2008

Other Studies

12 other studies available for thyroxine and Vitiligo

ArticleYear
Vitiligo and Hashimoto's thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis.
    Medical hypotheses, 2019, Volume: 128

    Topics: Animals; Autoimmune Diseases; Autoimmunity; Benzoquinones; Disease Models, Animal; Hashimoto Disease

2019
High prevalence of autoimmune thyroiditis in children and adolescents with vitiligo.
    Hormone research in paediatrics, 2013, Volume: 79

    Topics: Adolescent; Autoimmune Diseases; Child; Female; Humans; Iodide Peroxidase; Male; Netherlands; Preval

2013
Pediatric Patients with Vitiligo in Eastern China: Abnormalities in 145 Cases Based on Thyroid Function Tests and Immunological Findings.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Oct-23, Volume: 21

    Topics: Adolescent; Antibodies, Antinuclear; Autoimmune Diseases; Child; Child, Preschool; China; Complement

2015
Effects of age of onset on disease characteristics in non-segmental vitiligo.
    International journal of dermatology, 2017, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Aged; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases;

2017
The first childhood case with coexisting Hashimoto thyroiditis, vitiligo and autoimmune hepatitis.
    The Turkish journal of pediatrics, 2016, Volume: 58, Issue:4

    Topics: Adolescent; Azathioprine; Glucocorticoids; Hashimoto Disease; Hepatitis, Autoimmune; Humans; Male; P

2016
Relevance of autoimmune thyroiditis in children and adolescents with vitiligo.
    International journal of dermatology, 2011, Volume: 50, Issue:2

    Topics: Adolescent; Age of Onset; Autoantibodies; Child; Child, Preschool; Comorbidity; Female; Humans; Inci

2011
The white butterfly.
    Lancet (London, England), 2002, Nov-23, Volume: 360, Issue:9346

    Topics: Female; Humans; Hypothyroidism; Middle Aged; Thyroxine; Vitiligo

2002
ADDISON'S DISEASE WITH VITILIGO, ADDISONIAN ANAEMIA, PRIMARY HYPOTHROIDISM AND DIABETES MELLITUS.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58

    Topics: Addison Disease; Adrenal Insufficiency; Anemia, Pernicious; Autoimmune Diseases; Cortisone; Diabetes

1965
Association of vitiligo, morphea, and Hashimoto's thyroiditis.
    International journal of dermatology, 2004, Volume: 43, Issue:3

    Topics: Diagnosis, Differential; Female; Humans; Middle Aged; Scleroderma, Localized; Thorax; Thyroiditis, A

2004
Connective tissue panniculitis in a child with vitiligo and Hashimoto's thyroiditis.
    The Australasian journal of dermatology, 2006, Volume: 47, Issue:1

    Topics: Biopsy, Needle; Child; Connective Tissue; Drug Therapy, Combination; Female; Follow-Up Studies; Huma

2006
Thyroid function in vitiligo.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Oct-09, Volume: 106, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Hypothyroidism; Male; Middle Aged; Thyroid Gland; Th

1980
Vitiligo, autoimmune thyroiditis: a rare thyroid cancer arising with bone metastates on maxillofacial area.
    Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Bone Neoplasms; Child; Child, Preschool;

1999