Page last updated: 2024-11-06

thyroxine and Vitamin D Deficiency

thyroxine has been researched along with Vitamin D Deficiency in 23 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Vitamin D Deficiency: A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406)

Research Excerpts

ExcerptRelevanceReference
"This study deals with the relationship between the occurrence of hypercalcemia and the administration of prophylactic doses of vitamin D in children with hypothyroidism, before and during L-thyroxine (LT4) treatment."5.06[Prophylaxis of vitamin D deficiency in hypothyroidism in the newborn infant]. ( Czernichow, P; Farriaux, JP; Garabedian, M; Leger, J; Tau, C, 1989)
" The presence of primary autoimmune hypothyroidism makes this case specific, since the inability for optimal substitution therapy with a high daily dose of levothyroxine provoked the suspicion of celiac disease."3.81Osteoporosis reversibility in a patient with celiac disease and primary autoimmune hypothyroidism on gluten free diet--a case report. ( Bajkin, I; Ičin, T; Kovačev-Zavišić, B; Medić-Stojanoska, M; Novaković-Paro, J, 2015)
" Vitamin D25 and D1,25 levels were lower in subjects with larger burns or inhalation injury, as well as those treated with thyroxine or oxandrolone."3.72Hypovitaminosis D in acutely injured pediatric burn patients. ( Gottschlich, MM; Khoury, J; Mayes, T; Warden, GD, 2004)
"StatPearls [Internet]."3.30A Prospective Study to Evaluate the Possible Role of Cholecalciferol Supplementation on Autoimmunity in Hashimoto's Thyroiditis. ( Bhakat, B; Charaborty, SK; Das, S; Pal, J; SircarMedical, NR, 2023)
"Vitamin D deficiency is widespread worldwide and associated with negative effects on maternal and neonatal health."1.91The impact of vitamin D deficiency on some biochemical parameters and clinical outcome in Palestinian pregnant women during the first trimester. ( Abed El-Nabi, SR; Laqqan, MM; Mwafy, SN; Yassin, MM, 2023)
"Vitamin D deficiency was defined as 25(OH)D < 20 ng/mL."1.91Vitamin D Deficiency Is Associated with Impaired Sensitivity to Thyroid Hormones in Euthyroid Adults. ( An, Y; Liu, J; Su, J; Wang, G; Wang, Y; Zhou, L, 2023)
"Vitamin D deficiency was defined as serum concentrations of the main circulating vitamin D, 25-hydroxy vitamin D [25(OH)D], below 50 nmol/L."1.91Relationship between serum vitamin D and thyroid hormone profiles in male patients with alcohol dependence. ( Liu, Y; Pang, L; Wang, Y; Xu, Y; Zhang, X, 2023)
"Vitamin D deficiency has been identified as a risk factor for a number of autoimmune diseases including type 1 diabetes and multiple sclerosis."1.38Vitamin D deficiency is not associated with early stages of thyroid autoimmunity. ( Badenhoop, K; Effraimidis, G; Tijssen, JG; Wiersinga, WM, 2012)
"An ectopic supernumerary parathyroid adenoma was identified and removed from the right tracheoesophageal groove during bilateral exploration of neck and the patient was completely cured after surgery."1.38A unique ca(u)se of quadriparesis. ( Balachandran, K; Chandra, S; Halanaik, D; Kamalanathan, S, 2012)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's11 (47.83)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Mwafy, SN1
Abed El-Nabi, SR1
Laqqan, MM1
Yassin, MM1
Bhakat, B1
Pal, J1
Das, S1
Charaborty, SK1
SircarMedical, NR1
Zhou, L1
Wang, Y2
Su, J1
An, Y1
Liu, J1
Wang, G1
Liu, Y1
Xu, Y1
Pang, L1
Zhang, X1
Kuroda, K1
Matsumura, Y1
Ikemoto, Y1
Segawa, T1
Hashimoto, T1
Fukuda, J1
Nakagawa, K1
Uchida, T1
Ochiai, A1
Horimoto, Y1
Arakawa, A1
Nojiri, S1
Itakura, A1
Sugiyama, R1
Cohen, PR1
Kurzrock, R1
Kovačev-Zavišić, B1
Ičin, T1
Novaković-Paro, J1
Medić-Stojanoska, M1
Bajkin, I1
Krysiak, R1
Kowalcze, K1
Okopien, B1
Şıklar, Z1
Karataş, D1
Doğu, F1
Hacıhamdioğlu, B1
İkincioğulları, A1
Berberoğlu, M1
Kim, D1
Muscogiuri, G1
Mari, D1
Prolo, S1
Fatti, LM1
Cantone, MC1
Garagnani, P1
Arosio, B1
Di Somma, C1
Vitale, G1
Goswami, R1
Marwaha, RK1
Gupta, N1
Tandon, N1
Sreenivas, V1
Tomar, N1
Ray, D1
Kanwar, R1
Agarwal, R1
Effraimidis, G1
Badenhoop, K1
Tijssen, JG1
Wiersinga, WM1
Yasuda, T1
Okamoto, Y1
Hamada, N1
Miyashita, K1
Takahara, M1
Sakamoto, F1
Miyatsuka, T1
Kitamura, T1
Katakami, N1
Kawamori, D1
Otsuki, M1
Matsuoka, TA1
Kaneto, H1
Shimomura, I1
Kamalanathan, S1
Balachandran, K1
Halanaik, D1
Chandra, S1
Camurdan, OM1
Döğer, E1
Bideci, A1
Celik, N1
Cinaz, P1
Gottschlich, MM1
Mayes, T1
Khoury, J1
Warden, GD1
Mohan, HK1
Groves, AM1
Fogelman, I1
Clarke, SE1
Mellanby, RJ1
Mellor, P1
Villiers, EJ1
Herrtage, ME1
Halsall, D1
O'Rahilly, S1
McNeil, PE1
Mee, AP1
Berry, JL1
Smotkin-Tangorra, M1
Purushothaman, R1
Gupta, A1
Nejati, G1
Anhalt, H1
Ten, S1
Leger, J1
Tau, C1
Garabedian, M1
Farriaux, JP1
Czernichow, P1
Jacob, M1
Forbes, RM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vitamin D Deficiency in Acutely Injured Pediatric Burn Patients: Incidence, Etiology, Metabolic Sequelae and Prevention[NCT00536276]Phase 150 participants (Actual)Interventional2003-03-31Completed
Vitamin D Concentrations and Their Effect on Glucose Metabolism in Pediatrics[NCT01386736]Phase 4110 participants (Anticipated)Interventional2011-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for thyroxine and Vitamin D Deficiency

ArticleYear
A Prospective Study to Evaluate the Possible Role of Cholecalciferol Supplementation on Autoimmunity in Hashimoto's Thyroiditis.
    The Journal of the Association of Physicians of India, 2023, Volume: 71, Issue:1

    Topics: Adult; Autoimmunity; Cholecalciferol; Dietary Supplements; Female; Graves Disease; Hashimoto Disease

2023
[Prophylaxis of vitamin D deficiency in hypothyroidism in the newborn infant].
    Archives francaises de pediatrie, 1989, Volume: 46, Issue:8

    Topics: Calcifediol; Drug Administration Schedule; Humans; Hypercalcemia; Hypothyroidism; Infant, Newborn; T

1989

Other Studies

21 other studies available for thyroxine and Vitamin D Deficiency

ArticleYear
The impact of vitamin D deficiency on some biochemical parameters and clinical outcome in Palestinian pregnant women during the first trimester.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Arabs; Autoantibodies; Case-Control Studies; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy T

2023
Vitamin D Deficiency Is Associated with Impaired Sensitivity to Thyroid Hormones in Euthyroid Adults.
    Nutrients, 2023, Aug-24, Volume: 15, Issue:17

    Topics: Adult; Humans; Thyroid Hormones; Thyrotropin; Thyroxine; Vitamin D; Vitamin D Deficiency; Vitamins

2023
Relationship between serum vitamin D and thyroid hormone profiles in male patients with alcohol dependence.
    BMC psychiatry, 2023, 10-24, Volume: 23, Issue:1

    Topics: Alcoholism; Humans; Male; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin D; Vit

2023
Analysis of the risk factors and treatment for repeated implantation failure: OPtimization of Thyroid function, IMmunity, and Uterine Milieu (OPTIMUM) treatment strategy.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2021, Volume: 85, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anticoagulants; Aspirin; Autoantibodies; Embryo Implantation; Endometr

2021
Anakinra-responsive lichen planus in a woman with Erdheim-Chester disease: a therapeutic enigma.
    Dermatology online journal, 2014, Jan-15, Volume: 20, Issue:1

    Topics: Adult; Cetirizine; Deamino Arginine Vasopressin; Diabetes Insipidus; Drug Eruptions; Erdheim-Chester

2014
4 important blood tests for women--and what the results mean. Here's why every woman needs to know her numbers.
    Harvard women's health watch, 2014, Volume: 21, Issue:6

    Topics: Blood Glucose; Female; Health Knowledge, Attitudes, Practice; Humans; Lipids; Thyroid Function Tests

2014
Osteoporosis reversibility in a patient with celiac disease and primary autoimmune hypothyroidism on gluten free diet--a case report.
    Vojnosanitetski pregled, 2015, Volume: 72, Issue:1

    Topics: Calcium; Celiac Disease; Cholecalciferol; Diet, Gluten-Free; Female; Humans; Hyperparathyroidism, Se

2015
The effect of vitamin D on thyroid autoimmunity in non-lactating women with postpartum thyroiditis.
    European journal of clinical nutrition, 2016, Volume: 70, Issue:5

    Topics: Adult; Autoantibodies; Case-Control Studies; Dietary Supplements; Female; Humans; Iodide Peroxidase;

2016
Regulatory T Cells and Vitamin D Status in Children with Chronic Autoimmune Thyroiditis.
    Journal of clinical research in pediatric endocrinology, 2016, Sep-01, Volume: 8, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Female; Flow Cytometry; Forkhead Transcription

2016
Low vitamin D status is associated with hypothyroid Hashimoto's thyroiditis.
    Hormones (Athens, Greece), 2016, Volume: 15, Issue:3

    Topics: Adult; Autoantibodies; Biomarkers; Cross-Sectional Studies; Female; Graves Disease; Hashimoto Diseas

2016
25 Hydroxyvitamin D Deficiency and Its Relationship to Autoimmune Thyroid Disease in the Elderly.
    International journal of environmental research and public health, 2016, 08-26, Volume: 13, Issue:9

    Topics: Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Female; Humans; Iodide Peroxidase; Iron-Bindi

2016
Prevalence of vitamin D deficiency and its relationship with thyroid autoimmunity in Asian Indians: a community-based survey.
    The British journal of nutrition, 2009, Volume: 102, Issue:3

    Topics: Adolescent; Adult; Asian People; Autoantibodies; Autoimmune Diseases; Chi-Square Distribution; Femal

2009
Vitamin D deficiency is not associated with early stages of thyroid autoimmunity.
    European journal of endocrinology, 2012, Volume: 167, Issue:1

    Topics: Adult; Autoantibodies; Case-Control Studies; Cross-Sectional Studies; Female; Humans; Iodide Peroxid

2012
Serum vitamin D levels are decreased and associated with thyroid volume in female patients with newly onset Graves' disease.
    Endocrine, 2012, Volume: 42, Issue:3

    Topics: Adult; Body Mass Index; Calcifediol; Calcium; Female; Graves Disease; Humans; Immunoenzyme Technique

2012
A unique ca(u)se of quadriparesis.
    BMJ case reports, 2012, Jun-21, Volume: 2012

    Topics: Adenoma; Adult; Cholecalciferol; Female; Humans; Hyperparathyroidism, Primary; Parathyroid Neoplasms

2012
Vitamin D status in children with Hashimoto thyroiditis.
    Journal of pediatric endocrinology & metabolism : JPEM, 2012, Volume: 25, Issue:5-6

    Topics: Adolescent; Alkaline Phosphatase; Calcium; Child; Female; Hashimoto Disease; Humans; Male; Parathyro

2012
Hypovitaminosis D in acutely injured pediatric burn patients.
    Journal of the American Dietetic Association, 2004, Volume: 104, Issue:6

    Topics: Adolescent; Anabolic Agents; Burns; Child; Child, Preschool; Ergocalciferols; Growth Hormone; Humans

2004
Thyroid hormone and parathyroid hormone competing to maintain calcium levels in the presence of vitamin D deficiency.
    Thyroid : official journal of the American Thyroid Association, 2004, Volume: 14, Issue:9

    Topics: Calcium; Female; Homeostasis; Humans; Middle Aged; Parathyroid Hormone; Thyrotoxicosis; Thyroxine; V

2004
Hypercalcaemia associated with granulomatous lymphadenitis and elevated 1,25 dihydroxyvitamin D concentration in a dog.
    The Journal of small animal practice, 2006, Volume: 47, Issue:4

    Topics: Animals; Biopsy, Fine-Needle; Calcitriol; Dog Diseases; Dogs; Female; Granuloma; Hypercalcemia; Immu

2006
Prevalence of vitamin D insufficiency in obese children and adolescents.
    Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:7

    Topics: Adolescent; Aspartate Aminotransferases; Blood Glucose; CD13 Antigens; Child; Cholesterol; Female; H

2007
Effect of vitamin D deficiency and the role of citrate in kidney calcification of magnesium-deficient rats.
    The Journal of nutrition, 1970, Volume: 100, Issue:2

    Topics: Animals; Calcinosis; Calcium; Citrates; Depression, Chemical; Diet; Feces; Galactose; Kidney Disease

1970