Page last updated: 2024-11-06

thyroxine and Venous Thrombosis

thyroxine has been researched along with Venous Thrombosis in 10 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
" We determined the associations of levels of free thyroxine (FT4), thyroid-stimulating hormone (TSH) and anti-thyroid peroxidase antibodies (antiTPO) with levels of coagulation factors and the risk of venous thrombosis."7.80High levels of procoagulant factors mediate the association between free thyroxine and the risk of venous thrombosis: the MEGA study. ( Brandjes, DP; Büller, HR; Cannegieter, SC; Debeij, J; Dekkers, OM; Doggen, CJ; Gerdes, VE; Rosendaal, FR; Smit, JW; van Zaane, B; van Zanten, AP, 2014)
"Relative and absolute risks for venous thrombosis were calculated for different cut-off levels of thyroid hormones on the basis of percentiles in the controls and different times between blood sampling and thombosis."5.38Increased levels of free thyroxine and risk of venous thrombosis in a large population-based prospective study. ( Asvold, BO; Cannegieter, SC; Christiansen, SC; Debeij, J; Dekkers, OM; Hammerstrom, J; Naess, IA; Rosendaal, FR, 2012)
" We determined the associations of levels of free thyroxine (FT4), thyroid-stimulating hormone (TSH) and anti-thyroid peroxidase antibodies (antiTPO) with levels of coagulation factors and the risk of venous thrombosis."3.80High levels of procoagulant factors mediate the association between free thyroxine and the risk of venous thrombosis: the MEGA study. ( Brandjes, DP; Büller, HR; Cannegieter, SC; Debeij, J; Dekkers, OM; Doggen, CJ; Gerdes, VE; Rosendaal, FR; Smit, JW; van Zaane, B; van Zanten, AP, 2014)
" We present a case of primary hypothyroidism who presented with euvolemic hyponatremia and DVT that required thyroxine replacement and correction of hyponatremia."3.77Deep vein thrombosis and euvolemic hyponatremia in a hypothyroid patient. ( Kumar, SS; Prasad, CV; Rajesh, J; Shakir, RM; Umadevi, V; Vijayashankar, C, 2011)
"This implies an increased risk of venous thrombosis during hyperthyroidism."2.76Alterations in coagulation and fibrinolysis after levothyroxine exposure in healthy volunteers: a controlled randomized crossover study. ( Brandjes, DP; Büller, HR; Cannegieter, SC; Debeij, J; Dekkers, OM; Gerdes, VE; Meijers, JC; Squizzato, A; Van Zaane, B; Van Zanten, AP, 2011)
"Hypothyroidism is associated with an increased bleeding risk, whereas hyperthyroidism leads to an increased risk of venous thrombosis."2.58Thyroid Disorders and Hemostasis. ( Elbers, LPB; Gerdes, VEA; Squizzato, A, 2018)
"A personal history of malignancy and type 2 diabetes increase the risk of PMVT."1.48Assessing risk factors, presentation, and management of portomesenteric vein thrombosis after sleeve gastrectomy: a multicenter case-control study. ( Blanco, DG; Boyce, SG; De La Cruz-Munoz, N; Domkowski, P; Funes, DR; Ghanem, M; Jawad, MA; Menzo, EL; Moon, RC; Radecke, J; Rosenthal, R; Teixeira, AF; Young, MK, 2018)
"Relative and absolute risks for venous thrombosis were calculated for different cut-off levels of thyroid hormones on the basis of percentiles in the controls and different times between blood sampling and thombosis."1.38Increased levels of free thyroxine and risk of venous thrombosis in a large population-based prospective study. ( Asvold, BO; Cannegieter, SC; Christiansen, SC; Debeij, J; Dekkers, OM; Hammerstrom, J; Naess, IA; Rosendaal, FR, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moon, RC1
Ghanem, M1
Teixeira, AF1
De La Cruz-Munoz, N1
Young, MK1
Domkowski, P1
Radecke, J1
Boyce, SG1
Rosenthal, R1
Menzo, EL1
Blanco, DG1
Funes, DR1
Jawad, MA1
Elbers, LPB1
Squizzato, A3
Gerdes, VEA1
Raps, M1
Curvers, J1
Helmerhorst, FM1
Ballieux, BE1
Rosing, J1
Thomassen, S1
Rosendaal, FR3
van Vliet, HA1
Debeij, J3
van Zaane, B3
Dekkers, OM3
Doggen, CJ1
Smit, JW1
van Zanten, AP3
Brandjes, DP3
Büller, HR3
Gerdes, VE3
Cannegieter, SC4
Huijgen, R1
Fliers, E1
Meijers, JC1
Umadevi, V1
Rajesh, J1
Kumar, SS1
Shakir, RM1
Vijayashankar, C1
Prasad, CV1
Asvold, BO1
Christiansen, SC1
Naess, IA1
Hammerstrom, J1
Füessl, HS1
Vaidya, B1
Coulthard, A1
Goonetilleke, A1
Burn, DJ1
James, RA1
Kendall-Taylor, P1

Reviews

1 review available for thyroxine and Venous Thrombosis

ArticleYear
Thyroid Disorders and Hemostasis.
    Seminars in thrombosis and hemostasis, 2018, Volume: 44, Issue:7

    Topics: Goiter; Hemostasis; Humans; Hypothyroidism; Risk Factors; Thrombophilia; Thyroxine; Venous Thrombosi

2018

Trials

1 trial available for thyroxine and Venous Thrombosis

ArticleYear
Alterations in coagulation and fibrinolysis after levothyroxine exposure in healthy volunteers: a controlled randomized crossover study.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:9

    Topics: Adult; Blood Coagulation; Blood Coagulation Factors; Cross-Over Studies; Female; Fibrinolysis; Human

2011

Other Studies

8 other studies available for thyroxine and Venous Thrombosis

ArticleYear
Assessing risk factors, presentation, and management of portomesenteric vein thrombosis after sleeve gastrectomy: a multicenter case-control study.
    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2018, Volume: 14, Issue:4

    Topics: Adult; Aged; Anticoagulants; Bariatric Surgery; Drug Therapy, Combination; Enoxaparin; Epidemiologic

2018
Thyroid function, activated protein C resistance and the risk of venous thrombosis in users of hormonal contraceptives.
    Thrombosis research, 2014, Volume: 133, Issue:4

    Topics: Activated Protein C Resistance; Adolescent; Adult; Contraceptive Devices, Female; Contraceptives, Or

2014
High levels of procoagulant factors mediate the association between free thyroxine and the risk of venous thrombosis: the MEGA study.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Coagulation; Blood Coagulation Factors; Case-Control Stud

2014
Increasing levels of free thyroxine as a risk factor for a first venous thrombosis: a case-control study.
    Blood, 2010, Jun-03, Volume: 115, Issue:22

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Case-Control Studies; Conf

2010
Deep vein thrombosis and euvolemic hyponatremia in a hypothyroid patient.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Diagnosis, Differential; Female; Fibrinolytic Agents; Heparin; Humans; Hyponatremia; Hypothyroidism;

2011
Increased levels of free thyroxine and risk of venous thrombosis in a large population-based prospective study.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Biomarkers; Case-Control Studies; Female; Humans; Lo

2012
[Also in pregnancy the family practitioner is consulted].
    MMW Fortschritte der Medizin, 2007, Oct-25, Volume: 149, Issue:43

    Topics: Anti-Bacterial Agents; Anticoagulants; Antithyroid Agents; Bacterial Infections; Family Practice; Fe

2007
Cerebral venous sinus thrombosis: a late sequel of invasive fibrous thyroiditis.
    Thyroid : official journal of the American Thyroid Association, 1998, Volume: 8, Issue:9

    Topics: Cerebral Veins; Female; Fibrosis; Heparin; Humans; Jugular Veins; Magnetic Resonance Angiography; Ma

1998