thyroxine has been researched along with Stroke in 34 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigate the relationships between free thyroxine (FT4), brain frailty and clock drawing test (CDT) performance in patients with acute minor stroke or transient ischaemic attack (TIA)." | 8.12 | Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack. ( Cao, Y; Guo, Z; Hou, J; Huang, Z; Liu, CF; Wang, H; Wang, R; Xiao, G; Xu, G; Xu, J; You, S; Yu, S, 2022) |
| "Elevated concentrations of C-reactive protein (CRP) and decreased concentrations of triiodothyronine (T3) were shown to predict poor outcomes in patients with stroke." | 7.80 | Ischemic stroke functional outcomes are independently associated with C-reactive protein concentrations and cognitive outcomes with triiodothyronine concentrations: a pilot study. ( Bunevicius, A; Bunevicius, R; Janusonis, V; Kazlauskas, H; Raskauskiene, N, 2014) |
| " Hypothyroidism or hyperthyroidism was diagnosed by free thyroxine index measurements at baseline evaluation and incident events were determined from hospital records and death certificates during follow-up." | 7.73 | Free thyroxine index and risk of stroke: results from the National Health and Nutrition Examination Survey Follow-up Study. ( Divani, AA; Giles, WH; Kirmani, JF; Nasar, A; Qureshi, AI; Suri, FK, 2006) |
| "In patients with newly treated hypothyroidism, cardiovascular event rates were similar for generic and brand L-T4." | 5.51 | Comparison of Incident Cardiovascular Event Rates Between Generic and Brand l-Thyroxine for the Treatment of Hypothyroidism. ( Bernet, V; Kusumoto, F; Mwangi, R; Sangaralingham, LR; Smallridge, RC; Van Houten, H, 2019) |
| "Subclinical hypothyroidism (SCH) is an asymptomatic condition associated with increased thyroid-stimulating hormone (TSH) >4 mIU/L with normal thyroxine (T4) and triidothyronine (T3) levels." | 5.05 | The current debate over treatment of subclinical hypothyroidism to prevent cardiovascular complications. ( Chrysant, SG, 2020) |
| " In this study, we investigate the relationships between free thyroxine (FT4), brain frailty and clock drawing test (CDT) performance in patients with acute minor stroke or transient ischaemic attack (TIA)." | 4.12 | Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack. ( Cao, Y; Guo, Z; Hou, J; Huang, Z; Liu, CF; Wang, H; Wang, R; Xiao, G; Xu, G; Xu, J; You, S; Yu, S, 2022) |
| "Mendelian randomization analyses for stroke and CAD using genetic instruments associated with normal range thyrotropin (TSH) and free thyroxine levels or Hashimoto's thyroiditis and Graves' disease." | 3.96 | Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study. ( Chaker, L; Del Greco M, F; Deloukas, P; Kus, A; Marouli, E; Medici, M; Peeters, R; Teumer, A, 2020) |
| "Serum triiodothyronine (T3) concentration was reported to be associated with the prognosis after acute ischemic stroke." | 3.91 | The prognostic value of total T3 after acute cerebral infarction is age-dependent: a retrospective study on 768 patients. ( Hu, XY; Li, LQ; Li, WY; Lv, W; Xu, XY, 2019) |
| "Elevated concentrations of C-reactive protein (CRP) and decreased concentrations of triiodothyronine (T3) were shown to predict poor outcomes in patients with stroke." | 3.80 | Ischemic stroke functional outcomes are independently associated with C-reactive protein concentrations and cognitive outcomes with triiodothyronine concentrations: a pilot study. ( Bunevicius, A; Bunevicius, R; Janusonis, V; Kazlauskas, H; Raskauskiene, N, 2014) |
| " Rates of first stroke during follow-up in thyroxine-treated patients with AIT (n = 34,907) were compared with those in matched individuals without AIT (n = 149,632) using random-effects Poisson regression models." | 3.80 | Autoimmune thyroiditis as a risk factor for stroke: a historical cohort study. ( Karch, A; Thomas, SL, 2014) |
| "The relationship between the content of serum hormones (thyrotrophic hormone, thyroxin, dehydroepiandrosterone (DHEA), DHEA sulfate, prolactin) and cognitive impairment at the acute phase of ischemic stroke in the 1(st), 7(th) and 21(st) day was investigated." | 3.79 | [Hormonal markers of cognitive impairment in patients with the first stroke]. ( Gudkova, VV; Kispaeva, TT; Kol'tsova, EA; Ostrovtsev, IV, 2013) |
| " Hypothyroidism or hyperthyroidism was diagnosed by free thyroxine index measurements at baseline evaluation and incident events were determined from hospital records and death certificates during follow-up." | 3.73 | Free thyroxine index and risk of stroke: results from the National Health and Nutrition Examination Survey Follow-up Study. ( Divani, AA; Giles, WH; Kirmani, JF; Nasar, A; Qureshi, AI; Suri, FK, 2006) |
| " This risk was increased in those who took a higher dosage of levothyroxine (HR: 1." | 1.51 | Increased cardiovascular risk in thyroid cancer patients taking levothyroxine: a nationwide cohort study in Korea. ( Cho, B; Guallar, E; Lim, H; Park, JH; Park, Y; Shin, DW; Song, SO; Suh, B; Yun, JM, 2019) |
| "In patients with newly treated hypothyroidism, cardiovascular event rates were similar for generic and brand L-T4." | 1.51 | Comparison of Incident Cardiovascular Event Rates Between Generic and Brand l-Thyroxine for the Treatment of Hypothyroidism. ( Bernet, V; Kusumoto, F; Mwangi, R; Sangaralingham, LR; Smallridge, RC; Van Houten, H, 2019) |
| "Infants and children present with seizures and stroke-like episodes with focal neurologic deficits." | 1.35 | Central hypothyroidism and Sturge-Weber syndrome. ( Bellamkonda, S; Cohen, BA; Comi, AM; Ferenc, LM; Germain-Lee, EL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 21 (61.76) | 24.3611 |
| 2020's | 7 (20.59) | 2.80 |
| Authors | Studies |
|---|---|
| Fani, L | 1 |
| Roa Dueñas, O | 1 |
| Bos, D | 1 |
| Vernooij, MW | 1 |
| Klaver, CCW | 1 |
| Ikram, MK | 1 |
| Peeters, RP | 1 |
| Ikram, MA | 1 |
| Chaker, L | 2 |
| Chubb, SAP | 1 |
| Peters, KE | 1 |
| Bruce, DG | 1 |
| Davis, WA | 1 |
| Davis, TME | 1 |
| Feng, Q | 1 |
| Li, Y | 1 |
| Zhu, Y | 1 |
| Xia, Y | 1 |
| Zhang, T | 1 |
| Hu, M | 1 |
| Li, W | 1 |
| Wu, M | 1 |
| Br, A | 1 |
| Chandra, BJS | 1 |
| Chrysant, SG | 1 |
| Marouli, E | 1 |
| Kus, A | 1 |
| Del Greco M, F | 1 |
| Peeters, R | 1 |
| Teumer, A | 1 |
| Deloukas, P | 1 |
| Medici, M | 1 |
| Guo, Z | 1 |
| Xu, G | 1 |
| Wang, R | 1 |
| Hou, J | 1 |
| Yu, S | 2 |
| Wang, H | 1 |
| Xu, J | 1 |
| You, S | 1 |
| Huang, Z | 1 |
| Xiao, G | 1 |
| Cao, Y | 1 |
| Liu, CF | 1 |
| Wändell, P | 1 |
| Carlsson, AC | 1 |
| Holzmann, MJ | 1 |
| Ärnlöv, J | 1 |
| Sundquist, J | 1 |
| Sundquist, K | 1 |
| Suda, S | 2 |
| Aoki, J | 2 |
| Shimoyama, T | 2 |
| Suzuki, K | 2 |
| Sakamoto, Y | 2 |
| Katano, T | 1 |
| Okubo, S | 2 |
| Nito, C | 2 |
| Nishiyama, Y | 1 |
| Mishina, M | 1 |
| Kimura, K | 2 |
| Jiang, X | 1 |
| Xing, H | 1 |
| Wu, J | 1 |
| Du, R | 1 |
| Liu, H | 1 |
| Chen, J | 1 |
| Wang, J | 1 |
| Wang, C | 1 |
| Wu, Y | 1 |
| Ambrosius, W | 2 |
| Rosinska, J | 1 |
| Michalak, S | 1 |
| Lukasik, M | 1 |
| Kazmierski, R | 2 |
| Kozubski, W | 1 |
| Dietlein, M | 1 |
| Drzezga, A | 1 |
| Suh, B | 1 |
| Shin, DW | 1 |
| Park, Y | 1 |
| Lim, H | 1 |
| Yun, JM | 1 |
| Song, SO | 1 |
| Park, JH | 1 |
| Cho, B | 1 |
| Guallar, E | 1 |
| Li, LQ | 1 |
| Xu, XY | 1 |
| Li, WY | 1 |
| Hu, XY | 1 |
| Lv, W | 1 |
| Smallridge, RC | 1 |
| Sangaralingham, LR | 1 |
| Mwangi, R | 1 |
| Kusumoto, F | 1 |
| Van Houten, H | 1 |
| Bernet, V | 1 |
| Bunevicius, A | 1 |
| Kazlauskas, H | 1 |
| Raskauskiene, N | 1 |
| Janusonis, V | 1 |
| Bunevicius, R | 1 |
| Watson, S | 1 |
| Raj, S | 1 |
| Eugster, E | 1 |
| Sanchez, J | 1 |
| Kispaeva, TT | 1 |
| Ostrovtsev, IV | 1 |
| Gudkova, VV | 1 |
| Kol'tsova, EA | 1 |
| Karch, A | 1 |
| Thomas, SL | 1 |
| Giri, A | 1 |
| Edwards, TL | 1 |
| LeGrys, VA | 1 |
| Lorenz, CE | 1 |
| Funk, MJ | 1 |
| Schectman, R | 1 |
| Heiss, G | 1 |
| Robinson, JG | 1 |
| Hartmann, KE | 1 |
| Forti, P | 1 |
| Maioli, F | 1 |
| Coveri, M | 1 |
| Nativio, V | 1 |
| Arnone, G | 1 |
| Loreti, A | 1 |
| Zoli, M | 1 |
| Sacquegna, T | 1 |
| Procaccianti, G | 1 |
| Liu, K | 1 |
| Khan, H | 1 |
| Geng, X | 1 |
| Zhang, J | 1 |
| Ding, Y | 1 |
| Muraga, K | 1 |
| Kanamaru, T | 1 |
| Abe, A | 1 |
| Comi, AM | 1 |
| Bellamkonda, S | 1 |
| Ferenc, LM | 1 |
| Cohen, BA | 1 |
| Germain-Lee, EL | 1 |
| Baek, JH | 1 |
| Chung, PW | 1 |
| Kim, YB | 1 |
| Moon, HS | 1 |
| Suh, BC | 1 |
| Jin, DK | 1 |
| Kim, BM | 1 |
| Rhee, EJ | 1 |
| Lee, YT | 1 |
| Park, KY | 1 |
| Jeong, SK | 1 |
| Seo, JY | 1 |
| Nam, HS | 1 |
| Park, HK | 1 |
| Gupta, V | 1 |
| Warot, AW | 1 |
| Adamczewska-Kociałkowska, D | 1 |
| Błazejewska, A | 1 |
| Ziemnicka, K | 1 |
| Nowinski, WL | 1 |
| Neidert, S | 1 |
| Katan, M | 1 |
| Schuetz, P | 1 |
| Fluri, F | 1 |
| Ernst, A | 1 |
| Bingisser, R | 1 |
| Kappos, L | 1 |
| Engelter, ST | 1 |
| Steck, A | 1 |
| Müller, B | 1 |
| Christ-Crain, M | 1 |
| Rosario, M | 1 |
| Song, SX | 1 |
| McCullough, LD | 1 |
| Huang, JS | 1 |
| Bai, JC | 1 |
| Huang, GL | 1 |
| Rekand, T | 1 |
| Vedeler, C | 1 |
| Gramstad, A | 1 |
| Bindoff, L | 1 |
| Alevizaki, M | 1 |
| Synetou, M | 1 |
| Xynos, K | 1 |
| Alevizaki, CC | 1 |
| Vemmos, KN | 1 |
| Qureshi, AI | 1 |
| Suri, FK | 1 |
| Nasar, A | 1 |
| Kirmani, JF | 1 |
| Divani, AA | 1 |
| Giles, WH | 1 |
| Doyle, KP | 1 |
| Suchland, KL | 1 |
| Ciesielski, TM | 1 |
| Lessov, NS | 1 |
| Grandy, DK | 1 |
| Scanlan, TS | 1 |
| Stenzel-Poore, MP | 1 |
3 reviews available for thyroxine and Stroke
| Article | Year |
|---|---|
The current debate over treatment of subclinical hypothyroidism to prevent cardiovascular complications.
Topics: Adult; Aged; Aged, 80 and over; Disease Management; Female; Heart Failure; Humans; Hypothyroidism; M | 2020 |
Prognostic value of thyroid hormones in acute ischemic stroke - a meta analysis.
Topics: Animals; Brain Ischemia; Humans; Odds Ratio; Stroke; Thyroid Hormones; Thyrotropin; Thyroxine | 2017 |
Pharmacological hypothermia: a potential for future stroke therapy?
Topics: Adenine Nucleotides; Adenosine; Animals; Cannabinoids; Humans; Hypothermia; Hypothermia, Induced; Ne | 2016 |
1 trial available for thyroxine and Stroke
| Article | Year |
|---|---|
The relationship between thyroid dysfunction, cardiovascular morbidity and mortality in type 2 diabetes: The Fremantle Diabetes Study Phase II.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Male; Myocardial Infarction; Stroke | 2022 |
30 other studies available for thyroxine and Stroke
| Article | Year |
|---|---|
Thyroid Status and Brain Circulation: The Rotterdam Study.
Topics: Aged; Brain; Cerebrovascular Circulation; Female; Humans; Male; Middle Aged; Netherlands; Risk Facto | 2022 |
Admission thyroid function in relation to 90-day outcome of acute ischemic stroke.
Topics: Humans; Ischemic Stroke; Stroke; Thyrotropin; Thyroxine; Triiodothyronine | 2023 |
Study of Thyroid Profi le in Patients with Ischemic Stroke at Presentation with Special Reference to Subclinical Hypothyroidism and Stroke Outcome.
Topics: Brain Ischemia; Humans; Hypothyroidism; Ischemic Stroke; Stroke; Thyrotropin; Thyroxine | 2020 |
Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study.
Topics: Adult; Atrial Fibrillation; Body Mass Index; Coronary Artery Disease; Datasets as Topic; Female; Gra | 2020 |
Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack.
Topics: Brain; Frailty; Humans; Ischemic Attack, Transient; Stroke; Thyroxine | 2022 |
Comparison of Mortality and Nonfatal Cardiovascular Events in Adults With Atrial Fibrillation With Versus Without Levothyroxine Treatment.
Topics: Age Factors; Aged; Aged, 80 and over; Atrial Fibrillation; Cause of Death; Female; Follow-Up Studies | 2017 |
Low Free Triiodothyronine at Admission Predicts Poststroke Infection.
Topics: Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Female; Humans; Japan; Logistic Models | 2018 |
Free thyroxine and TSH interact with secreted protein acidic and rich in cysteine-like 1 in ischemic stroke.
Topics: Brain Ischemia; Cysteine; Humans; Osteonectin; Stroke; Thyrotropin; Thyroxine | 2018 |
Topics: Atherosclerosis; Cognition Disorders; Drug Utilization; Heart Diseases; Humans; Hypothyroidism; Rena | 2018 |
Increased cardiovascular risk in thyroid cancer patients taking levothyroxine: a nationwide cohort study in Korea.
Topics: Adult; Brain Ischemia; Coronary Disease; Female; Health Surveys; Humans; Incidence; Male; Middle Age | 2019 |
The prognostic value of total T3 after acute cerebral infarction is age-dependent: a retrospective study on 768 patients.
Topics: Age Factors; Aged; Biomarkers; Brain Ischemia; Female; Humans; Male; Middle Aged; Odds Ratio; Progno | 2019 |
Comparison of Incident Cardiovascular Event Rates Between Generic and Brand l-Thyroxine for the Treatment of Hypothyroidism.
Topics: Adult; Aged; Atrial Fibrillation; Drugs, Generic; Female; Humans; Hypothyroidism; Insurance Claim Re | 2019 |
Ischemic stroke functional outcomes are independently associated with C-reactive protein concentrations and cognitive outcomes with triiodothyronine concentrations: a pilot study.
Topics: Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Cognition Disorders; Female; Humans; Male; | 2014 |
Acute mental status change as the presenting feature of adrenal insufficiency in a patient with autoimmune polyglandular syndrome type II and stroke.
Topics: Adolescent; Adrenal Insufficiency; Aggression; Anti-Inflammatory Agents; Confusion; Female; Humans; | 2014 |
[Hormonal markers of cognitive impairment in patients with the first stroke].
Topics: Aged; Biomarkers; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal | 2013 |
Autoimmune thyroiditis as a risk factor for stroke: a historical cohort study.
Topics: Adult; Aged; Cohort Studies; Databases, Factual; Female; Humans; Male; Middle Aged; Risk Factors; St | 2014 |
Subclinical hypothyroidism and risk for incident ischemic stroke among postmenopausal women.
Topics: Aged; Case-Control Studies; Female; Follow-Up Studies; Humans; Hypothyroidism; Ischemia; Middle Aged | 2014 |
Thyroid function tests and early outcomes of acute ischemic stroke in older euthyroid patients.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Humans; Logistic Models; Male; Stroke; Thyroid Func | 2015 |
Low free triiodothyronine predicts poor functional outcome after acute ischemic stroke.
Topics: Aged; Biomarkers; Brain; Brain Ischemia; Female; Hospitalization; Humans; Logistic Models; Male; Pro | 2016 |
Central hypothyroidism and Sturge-Weber syndrome.
Topics: Anticonvulsants; Child; Female; Glaucoma; Humans; Hypothyroidism; Magnetic Resonance Imaging; Male; | 2008 |
Favorable influence of subclinical hypothyroidism on the functional outcomes in stroke patients.
Topics: Aged; Female; Humans; Hypothyroidism; Male; Retrospective Studies; Statistics, Nonparametric; Stroke | 2010 |
Thyroid function and internal carotid artery stenosis in ischemic stroke.
Topics: Aged; Carotid Stenosis; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Multivar | 2010 |
Low free triiodothyronine levels are related to poor prognosis in acute ischemic stroke.
Topics: Aged; Aged, 80 and over; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Prospe | 2011 |
Anterior pituitary axis hormones and outcome in acute ischaemic stroke.
Topics: Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Epidemiologic Methods; Female; Human Growth Hor | 2011 |
An unusual case of stroke.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diuretics; Female; Furo | 2012 |
[Determining blood parameters FT3, FT4, T, E2 and cortisol to explore nature of cold syndrome and heat syndrome].
Topics: Adolescent; Adult; Aged; Communicable Diseases; Diagnosis, Differential; Estradiol; Female; Humans; | 2002 |
Hashimoto's encephalopathy: a treatable cause of mental impairment, stroke and seizures.
Topics: Female; Humans; Memory Disorders; Mental Disorders; Middle Aged; Seizures; Stroke; Thyroiditis, Auto | 2003 |
Hypothyroidism as a protective factor in acute stroke patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Chi-Square Distribution; Female; Humans; Hypothyroidism; Isc | 2006 |
Free thyroxine index and risk of stroke: results from the National Health and Nutrition Examination Survey Follow-up Study.
Topics: Adult; Aged; Data Collection; Female; Follow-Up Studies; Humans; Hyperthyroidism; Hypothyroidism; Ma | 2006 |
Novel thyroxine derivatives, thyronamine and 3-iodothyronamine, induce transient hypothermia and marked neuroprotection against stroke injury.
Topics: Animals; Behavior, Animal; Body Temperature; Brain Ischemia; Cells, Cultured; Humans; Hypothermia; I | 2007 |