Page last updated: 2024-11-06

thyroxine and Spinal Cord Injuries

thyroxine has been researched along with Spinal Cord Injuries in 8 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Physiologically complete cervical spinal cord transection results in motor and sensory quadriplegia and interruption of the sympathetic neural pathways; this condition leads to metabolic deficiencies suggestive of abnormal endocrine function."1.26Steady state hormonal secretion in traumatic quadriplegia. ( Campos, RJ; Carter, RE; Claus-Walker, J; Scurry, M, 1977)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kimura, H1
Yoshikawa, M1
Matsuda, R1
Toriumi, H1
Nishimura, F1
Hirabayashi, H1
Nakase, H1
Kawaguchi, S1
Ishizaka, S1
Sakaki, T1
Prakash, V2
Lin, MS1
Song, CH1
Perkash, I1
Tator, CH1
van der Jagt, RH1
Huang, TS1
Wang, YH1
Chiang, HS1
Lien, YN1
Cheville, AL1
Kirshblum, SC1
Claus-Walker, J1
Scurry, M1
Carter, RE1
Campos, RJ1
Berezin, M1
Ohry, A1
Shemesh, Y1
Zeilig, G1
Brooks, ME1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Provocative Testing Using LHRH and hCG of the Pituitary-Gonadal Axis in Persons With Spinal Cord Injury[NCT00223860]100 participants (Anticipated)Interventional2001-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for thyroxine and Spinal Cord Injuries

ArticleYear
Transplantation of embryonic stem cell-derived neural stem cells for spinal cord injury in adult mice.
    Neurological research, 2005, Volume: 27, Issue:8

    Topics: Animals; Cell Differentiation; Cell Line; Combined Modality Therapy; Female; Glial Fibrillary Acidic

2005
Low serum 3,3',5-triiodothyronine (T3) and reciprocally high serum 3,3',5'-triiodothyronine (reverse T3) concentration in spinal cord injury patients.
    The Journal of the American Paraplegia Society, 1983, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Aged; Humans; Male; Middle Aged; Paraplegia; Quadriplegia; Spinal Cord Injuries;

1983
Thyroid hypofunction in spinal cord injury patients.
    Paraplegia, 1980, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Humans; Hypothyroidism; Male; Middle Aged; Paralysis; Paraplegia; Q

1980
The effect of exogenous thyroid hormones on functional recovery of the rat after acute spinal cord compression injury.
    Journal of neurosurgery, 1980, Volume: 53, Issue:3

    Topics: Acute Disease; Animals; Female; Nerve Regeneration; Rats; Spinal Cord Compression; Spinal Cord Injur

1980
Pituitary-testicular and pituitary-thyroid axes in spinal cord-injured males.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing

1993
Thyroid hormone changes in chronic spinal cord injury.
    The journal of spinal cord medicine, 1995, Volume: 18, Issue:4

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Energy Metabolism; Euthyroid Sick Syndro

1995
Steady state hormonal secretion in traumatic quadriplegia.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:3

    Topics: Calcitonin; Growth Hormone; Hormones; Humans; Male; Parathyroid Hormone; Quadriplegia; Spinal Cord I

1977
Hyperprolactinemia, galactorrhea and amenorrhea in women with a spinal cord injury.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1989, Volume: 3, Issue:2

    Topics: Adult; Amenorrhea; Female; Follicle Stimulating Hormone; Galactorrhea; Growth Hormone; Humans; Hydro

1989