thyroxine has been researched along with Sleep Initiation and Maintenance Disorders in 7 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Old studies in animals and unblinded studies in a few hyperthyroid patients suggested that L -carnitine is a periferal antagonist of thyroid hormone action at least in some tissues." | 9.09 | Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. ( Benvenga, S; Campenni, A; Lapa, D; Ruggeri, RM; Russo, A; Trimarchi, F, 2001) |
| "To evaluate the long-term safety and subjective sleep effects of ramelteon in adults with chronic insomnia." | 5.14 | Safety and subjective sleep effects of ramelteon administration in adults and older adults with chronic primary insomnia: a 1-year, open-label study. ( Richardson, GS; Wang-Weigand, S; Zammit, G; Zhang, J, 2009) |
| "Old studies in animals and unblinded studies in a few hyperthyroid patients suggested that L -carnitine is a periferal antagonist of thyroid hormone action at least in some tissues." | 5.09 | Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. ( Benvenga, S; Campenni, A; Lapa, D; Ruggeri, RM; Russo, A; Trimarchi, F, 2001) |
| "Further, the relapse and recurrence rates within 3 months after respective treatments were also measured." | 2.78 | Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia. ( Gao, D; Jiang, CG; Yi, ML; Yue, FG; Zhang, T, 2013) |
| "This study included 30 patients with primary insomnia (PI), 30 patients with depression-comorbid insomnia (DCI), and 30 healthy controls for exploring the alterations in the hypothalamus-pituitary-adrenal/thyroid axes' hormones and gonadotropin-releasing hormone (GnRH)." | 1.39 | Alterations in hypothalamus-pituitary-adrenal/thyroid axes and gonadotropin-releasing hormone in the patients with primary insomnia: a clinical research. ( Chen, GH; Jiang, S; Li, ZH; Shen, J; Xia, L, 2013) |
| "Prednisone was started 1 d after RAI and withdrawn after 6 wk." | 1.36 | Lower dose prednisone prevents radioiodine-associated exacerbation of initially mild or absent graves' orbitopathy: a retrospective cohort study. ( Bartalena, L; Compri, E; Lai, A; Marino, F; Piantanida, E; Sassi, L; Sivelli, P; Tanda, ML, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, CG | 1 |
| Zhang, T | 1 |
| Yue, FG | 1 |
| Yi, ML | 1 |
| Gao, D | 1 |
| Xia, L | 1 |
| Chen, GH | 1 |
| Li, ZH | 1 |
| Jiang, S | 1 |
| Shen, J | 1 |
| Carney, RM | 1 |
| Freedland, KE | 1 |
| Steinmeyer, B | 1 |
| Rubin, EH | 1 |
| Mann, DL | 1 |
| Rich, MW | 1 |
| Richardson, GS | 1 |
| Zammit, G | 1 |
| Wang-Weigand, S | 1 |
| Zhang, J | 1 |
| Lai, A | 1 |
| Sassi, L | 1 |
| Compri, E | 1 |
| Marino, F | 1 |
| Sivelli, P | 1 |
| Piantanida, E | 1 |
| Tanda, ML | 1 |
| Bartalena, L | 1 |
| Mazur, A | 1 |
| Benvenga, S | 1 |
| Ruggeri, RM | 1 |
| Russo, A | 1 |
| Lapa, D | 1 |
| Campenni, A | 1 |
| Trimarchi, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 3, Open-label, Fixed-dose Study to Determine the Safety of Long-term Administration of TAK-375 in Subjects With Chronic Insomnia[NCT00671086] | Phase 3 | 1,213 participants (Actual) | Interventional | 2003-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for thyroxine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia.
Topics: Adrenocorticotropic Hormone; Adult; Anti-Anxiety Agents; Chronic Disease; Estazolam; Female; Humans; | 2013 |
Cardiac Risk Markers and Response to Depression Treatment in Patients With Coronary Heart Disease.
Topics: Antidepressive Agents; Biomarkers; C-Reactive Protein; Causality; Cognitive Behavioral Therapy; Comb | 2016 |
Safety and subjective sleep effects of ramelteon administration in adults and older adults with chronic primary insomnia: a 1-year, open-label study.
Topics: Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Indenes; | 2009 |
Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Administration, Oral; Adult; Asthenia; Biomarkers; Body Weight; Bone Density; Carnitine; Double-Blin | 2001 |
3 other studies available for thyroxine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Alterations in hypothalamus-pituitary-adrenal/thyroid axes and gonadotropin-releasing hormone in the patients with primary insomnia: a clinical research.
Topics: Adrenocorticotropic Hormone; Adult; Case-Control Studies; Corticotropin-Releasing Hormone; Female; G | 2013 |
Lower dose prednisone prevents radioiodine-associated exacerbation of initially mild or absent graves' orbitopathy: a retrospective cohort study.
Topics: Adult; Aged; Chi-Square Distribution; Female; Glucocorticoids; Graves Disease; Graves Ophthalmopathy | 2010 |
Do cortisol and thyroxin correlate with nervousness and depression among male army veterans?
Topics: Adult; Anxiety; Arousal; Depression; Fatigue; Humans; Hydrocortisone; Male; Middle Aged; Sleep Initi | 1994 |