thyroxine and Sleep Apnea, Obstructive
thyroxine has been researched along with Sleep Apnea, Obstructive in 13 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study shows that subclinical hypothyroidism and treatment with levothyroxine do not influence the prevalence and severity of OSA, while sleep propensity is increased by untreated subclinical hypothyroidism." | 5.11 | Influence of subclinical hypothyroidism and T4 treatment on the prevalence and severity of obstructive sleep apnoea syndrome (OSAS). ( Carpagnano, GE; Carratù, P; De Pergola, G; Di Gioia, G; Giorgino, R; Lacedonia, D; Maniscalco, M; Resta, O, 2005) |
| "Hypothyroidism probably plays a significant role in the pathogenesis of obstructive sleep apnea, the satisfactory results would be obtained by thyroxine replacement therapy, CPAP or surgical treatment can be used as adjuvant therapy in patients with this disease." | 3.72 | [Obstructive sleep apnea syndrome and hypothyroidism (a report of three cases)]. ( Jiang, G; Li, N; Sun, Y, 2004) |
| "Hypothyroidism can directly cause obstructive sleep apnea (OSA) but may also contribute to it through its impact on the metabolic syndrome." | 1.51 | Prevalence of newly established thyroid disorders in patients with moderate-to-severe obstructive sleep apnea syndrome. ( Bruyneel, M; Poppe, K; Veltri, F, 2019) |
| "Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA)." | 1.51 | Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus. ( Anothaisintawee, T; Chailurkit, LO; Chirakalwasan, N; Manodpitipong, A; Nimitphong, H; Pinyopodjanard, S; Reutrakul, S; Saetang, S; Siwasaranond, N; Sriphrapradang, C; Suntornlohanakul, O, 2019) |
| "Primary hypothyroidism is a common disorder often associated with depression." | 1.38 | "Myxedema madness" associated with newly diagnosed hypothyroidism and obstructive sleep apnea. ( Neal, JM; Yuhico, RJ, 2012) |
| "The relation between snoring and obstructive sleep apnea as well as hypothyroidism is the object of interest of many authors." | 1.34 | Sleep apnea syndrome and snoring in patients with hypothyroidism with relation to overweight. ( Kajdaniuk, D; Kazmierczak-Zagorska, Z; Marek, B; Misiolek, H; Misiolek, M; Namyslowski, G; Scierski, W; Zwirska-Korczala, K, 2007) |
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chiang, KY | 1 |
| Ma, TSK | 1 |
| Ip, MSM | 1 |
| Lui, MMS | 1 |
| Zhang, H | 1 |
| Yuan, J | 1 |
| Zhang, Y | 1 |
| Wei, Y | 1 |
| Xu, L | 1 |
| Zhou, F | 1 |
| Fan, X | 1 |
| Kang, C | 1 |
| Yang, J | 1 |
| Bruyneel, M | 1 |
| Veltri, F | 1 |
| Poppe, K | 1 |
| Sriphrapradang, C | 1 |
| Pinyopodjanard, S | 1 |
| Suntornlohanakul, O | 1 |
| Nimitphong, H | 1 |
| Chirakalwasan, N | 1 |
| Saetang, S | 1 |
| Anothaisintawee, T | 1 |
| Siwasaranond, N | 1 |
| Manodpitipong, A | 1 |
| Chailurkit, LO | 1 |
| Reutrakul, S | 1 |
| Takeuchi, S | 1 |
| Kitamura, T | 1 |
| Ohbuchi, T | 1 |
| Koizumi, H | 1 |
| Takahashi, R | 1 |
| Hohchi, N | 1 |
| Suzuki, H | 1 |
| Petrone, A | 1 |
| Mormile, F | 1 |
| Bruni, G | 1 |
| Quartieri, M | 1 |
| Bonsignore, MR | 1 |
| Marrone, O | 1 |
| Rosen, D | 1 |
| Bahammam, SA | 1 |
| Sharif, MM | 1 |
| Jammah, AA | 1 |
| Bahammam, AS | 1 |
| Koehler, C | 1 |
| Ginzkey, C | 1 |
| Kleinsasser, NH | 1 |
| Hagen, R | 1 |
| Reiners, C | 1 |
| Verburg, FA | 1 |
| Neal, JM | 1 |
| Yuhico, RJ | 1 |
| Jiang, G | 1 |
| Li, N | 1 |
| Sun, Y | 1 |
| Resta, O | 1 |
| Carratù, P | 1 |
| Carpagnano, GE | 1 |
| Maniscalco, M | 1 |
| Di Gioia, G | 1 |
| Lacedonia, D | 1 |
| Giorgino, R | 1 |
| De Pergola, G | 1 |
| Misiolek, M | 1 |
| Marek, B | 1 |
| Namyslowski, G | 1 |
| Scierski, W | 1 |
| Zwirska-Korczala, K | 1 |
| Kazmierczak-Zagorska, Z | 1 |
| Kajdaniuk, D | 1 |
| Misiolek, H | 1 |
Trials
1 trial available for thyroxine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Influence of subclinical hypothyroidism and T4 treatment on the prevalence and severity of obstructive sleep apnoea syndrome (OSAS).
Topics: Adult; Aged; Body Mass Index; Female; Humans; Hypothyroidism; Male; Middle Aged; Neck; Prevalence; S | 2005 |
Other Studies
12 other studies available for thyroxine and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Respiratory arrest requiring resuscitation as a rare presentation of obstructive sleep apnoea and hypothyroidism.
Topics: Aged; Cardiopulmonary Resuscitation; Continuous Positive Airway Pressure; Diagnosis, Differential; H | 2019 |
Neuroendocrine abnormalities associated with untreated first episode patients of major depressive disorder with comorbid obstructive sleep apnea.
Topics: Adrenocorticotropic Hormone; Adult; Biomarkers; Cohort Studies; Comorbidity; Cross-Sectional Studies | 2020 |
Prevalence of newly established thyroid disorders in patients with moderate-to-severe obstructive sleep apnea syndrome.
Topics: Adult; Aged; Body Mass Index; Continuous Positive Airway Pressure; Correlation of Data; Female; Huma | 2019 |
Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Male; Middle Aged; Prediabetic Sta | 2019 |
Relationship between sleep apnea and thyroid function.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Humans; Hypothyroidism; Japan; Male | 2015 |
Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment.
Topics: Case-Control Studies; Continuous Positive Airway Pressure; Euthyroid Sick Syndromes; Female; Humans; | 2016 |
Severe hypothyroidism presenting as obstructive sleep apnea.
Topics: Child, Preschool; Diagnosis, Differential; Down Syndrome; Female; Humans; Hypothyroidism; Severity o | 2010 |
Prevalence of thyroid disease in patients with obstructive sleep apnea.
Topics: Arabs; Body Mass Index; Female; Humans; Hypothyroidism; Male; Middle Aged; Polysomnography; Prevalen | 2011 |
Short-term severe thyroid hormone deficiency does not influence sleep parameters.
Topics: Adult; Aged; Arousal; Disorders of Excessive Somnolence; Female; Humans; Hypothyroidism; Iodine Radi | 2013 |
"Myxedema madness" associated with newly diagnosed hypothyroidism and obstructive sleep apnea.
Topics: Adult; Continuous Positive Airway Pressure; Humans; Hypothyroidism; Male; Myxedema; Psychotic Disord | 2012 |
[Obstructive sleep apnea syndrome and hypothyroidism (a report of three cases)].
Topics: Humans; Hypothyroidism; Male; Middle Aged; Positive-Pressure Respiration; Sleep Apnea, Obstructive; | 2004 |
Sleep apnea syndrome and snoring in patients with hypothyroidism with relation to overweight.
Topics: Adult; Aged; Body Mass Index; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Male; Mid | 2007 |