Page last updated: 2024-11-06

thyroxine and Shock, Septic

thyroxine has been researched along with Shock, Septic in 16 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Research Excerpts

ExcerptRelevanceReference
"Most patients with septic shock have low serum thyroid hormone levels, a condition known as non-thyroidal illness syndrome."2.94Non-thyroidal illness syndrome, the hidden player in the septic shock induced myocardial contractile depression. ( Lado-Abeal, J, 2020)
"Patients with septic shock were enrolled from August 2017 to July 2019."1.56Predictive value of thyroxine for prognosis in pediatric septic shock: a prospective observational study. ( Cui, Y; Dou, J; Miao, H; Song, J; Wang, C; Xiong, X; Zhang, Y, 2020)
"After sepsis was cured, there was no hormonal change, except in 3 NT."1.42Nonthyroidal illnesses syndrome in full-term newborns with sepsis. ( Araujo, MC; Carvalho, WB; Ceccon, ME; Diniz, EM; Silva, MH, 2015)
"Twenty-four children (13 boys) with septic shock and 25 children (14 boys) with sepsis were enrolled."1.34Thyroid function in children with sepsis and septic shock. ( Arun, S; Kabra, SK; Lodha, R; Sarthi, M; Vivekanandhan, S, 2007)
"Septic shock is the reason of human body organs dysfunctions including the hormonal system."1.33[Assessment of the release of thyroid hormones in septic shock--prognostic significance]. ( Borkowski, J; Czaban, SL; Jedynak, M; Siemiatkowski, A; Wołczyński, S, 2005)
"One hour of hemorrhagic shock in the dog produces alterations in thyroid hormone metabolism far exceeding those seen after elective surgery or thermal injury."1.27Thyroid hormone responses in hemorrhagic shock: study in dogs and preliminary findings in humans. ( Cowley, RA; Lang, DJ; Shatney, CH; Vitek, V, 1983)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's1 (6.25)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Song, J1
Cui, Y1
Wang, C1
Dou, J1
Miao, H1
Xiong, X1
Zhang, Y1
Lado-Abeal, J1
Silva, MH1
Araujo, MC1
Diniz, EM1
Ceccon, ME1
Carvalho, WB1
Meyer, S1
Schuetz, P1
Wieland, M1
Nusbaumer, C1
Mueller, B1
Christ-Crain, M1
Le Toux, AL1
Marliot, C1
Ramakers, M1
Hazera, P1
Yildizdaş, D1
Onenli-Mungan, N1
Yapicioğlu, H1
Topaloğlu, AK1
Sertdemir, Y1
Yüksel, B1
Borkowski, J1
Siemiatkowski, A1
Wołczyński, S1
Czaban, SL1
Jedynak, M1
Lodha, R1
Vivekanandhan, S1
Sarthi, M1
Arun, S1
Kabra, SK1
Müller, MJ1
Hesch, RD1
Zouaghi, H1
Savu, L1
Delorme, J1
Kleinknecht, D1
Nunez, EA1
Nagy, SU1
Csaba, G1
Bertók, L2
Vitek, V1
Shatney, CH1
Lang, DJ1
Cowley, RA1
Dennhardt, R1
Gramm, HJ1
Meinhold, K1
Voigt, K1
Hadjikostova, H1
Nicolov, NA1
Cryer, PE1
Herman, CM1
Sode, J1

Reviews

2 reviews available for thyroxine and Shock, Septic

ArticleYear
Syndromes related to defective iodothyronine metabolism.
    Hormone and metabolic research. Supplement series, 1984, Volume: 14

    Topics: Body Temperature Regulation; Catecholamines; Glucose; Humans; Infant, Newborn; Iodide Peroxidase; Ke

1984
Endotoxins and endocrine system.
    Domestic animal endocrinology, 1998, Volume: 15, Issue:5

    Topics: Animals; Bile Acids and Salts; Endotoxins; Humans; Immune System; Lipopolysaccharides; Neurosecretor

1998

Trials

2 trials available for thyroxine and Shock, Septic

ArticleYear
Non-thyroidal illness syndrome, the hidden player in the septic shock induced myocardial contractile depression.
    Medical hypotheses, 2020, Volume: 142

    Topics: Euthyroid Sick Syndromes; Humans; Prospective Studies; Sepsis; Shock, Septic; Thyroxine

2020
Thyroid hormone levels and their relationship to survival in children with bacterial sepsis and septic shock.
    Journal of pediatric endocrinology & metabolism : JPEM, 2004, Volume: 17, Issue:10

    Topics: Bacteremia; Child; Child, Preschool; Female; Humans; Male; Matched-Pair Analysis; Predictive Value o

2004

Other Studies

12 other studies available for thyroxine and Shock, Septic

ArticleYear
Predictive value of thyroxine for prognosis in pediatric septic shock: a prospective observational study.
    Journal of pediatric endocrinology & metabolism : JPEM, 2020, May-26, Volume: 33, Issue:5

    Topics: Child; Hospital Mortality; Humans; Intensive Care Units, Pediatric; Predictive Value of Tests; Progn

2020
Nonthyroidal illnesses syndrome in full-term newborns with sepsis.
    Archives of endocrinology and metabolism, 2015, Volume: 59, Issue:6

    Topics: Disease Progression; Euthyroid Sick Syndromes; Humans; Infant; Infant, Newborn; Sepsis; Shock, Septi

2015
Low triiodothyronine syndrome: a prognostic marker for outcome in sepsis?
    Endocrine, 2011, Volume: 39, Issue:2

    Topics: Aged; Biomarkers; Critical Care; Euthyroid Sick Syndromes; Female; Health Status Indicators; Humans;

2011
[Iode poisoning after several bandages].
    Annales francaises d'anesthesie et de reanimation, 2012, Volume: 31, Issue:10

    Topics: Anti-Infective Agents, Local; Bandages; Electroencephalography; Humans; Hydrocarbons, Iodinated; Hyp

2012
[Assessment of the release of thyroid hormones in septic shock--prognostic significance].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2005, Volume: 18, Issue:103

    Topics: Adult; Aged; Case-Control Studies; Euthyroid Sick Syndromes; Humans; Male; Middle Aged; Predictive V

2005
Thyroid function in children with sepsis and septic shock.
    Acta paediatrica (Oslo, Norway : 1992), 2007, Volume: 96, Issue:3

    Topics: Child; Female; Humans; Male; Prospective Studies; Sepsis; Shock, Septic; Thyroid Hormones; Thyrotrop

2007
Loss of serum transcortin in human shock associated with severe infection by candida albicans.
    Acta endocrinologica, 1983, Volume: 102, Issue:2

    Topics: Adult; Candidiasis; Female; Haptoglobins; Humans; Hydrocortisone; Male; Prealbumin; Progesterone; Se

1983
Effect of thyrotropin (TSH) treatment on the responsiveness of the thyroid gland during endotoxin shock in adult rats.
    Acta physiologica Hungarica, 1983, Volume: 62, Issue:3-4

    Topics: Animals; Female; Male; Rats; Rats, Inbred Strains; Shock, Septic; Thyroid Gland; Thyrotropin; Thyrox

1983
Thyroid hormone responses in hemorrhagic shock: study in dogs and preliminary findings in humans.
    Surgery, 1983, Volume: 93, Issue:6

    Topics: Adult; Animals; Dogs; Female; Humans; Male; Pilot Projects; Shock, Hemorrhagic; Shock, Septic; Thyro

1983
Patterns of endocrine secretion during sepsis.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Diiodothyronines; Hormones; Humans; Hyd

1989
Changes in thyrotropic hormone, triiodothyronine and thyroxine level in endotoxin shock in rats.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1985, Volume: 26, Issue:3

    Topics: Animals; Male; Rats; Rats, Inbred Strains; Shock, Septic; Thyrotropin; Thyroxine; Triiodothyronine

1985
Carbohydrate metabolism in the baboon subjected to gram-negative (E. coli) septicemia. I. Hyperglycemia with depressed plasma insulin concentrations.
    Annals of surgery, 1971, Volume: 174, Issue:1

    Topics: 17-Hydroxycorticosteroids; Animals; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen

1971