Page last updated: 2024-11-06

thyroxine and Rhabdomyolysis

thyroxine has been researched along with Rhabdomyolysis in 26 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
"An 85-year-old woman with renal impairment and hypothyroidism was commenced on high dose simvastatin (80 mg) for better lipid control."7.74Simvastatin induced rhabdomyolysis and an important clinical link with hypothyroidism. ( Kiernan, TJ; McDermott, JH; Rochford, M, 2007)
"An 85-year-old woman with renal impairment and hypothyroidism was commenced on high dose simvastatin (80 mg) for better lipid control."3.74Simvastatin induced rhabdomyolysis and an important clinical link with hypothyroidism. ( Kiernan, TJ; McDermott, JH; Rochford, M, 2007)
" She had been treated for seven years with levothyroxine (T4) for hypothyroidism."3.68Rhabdomyolysis and acute renal failure in a patient with hypothyroidism. ( Enomoto, T; Hayashi, M; Kobayashi, T; Michikawa, M; Ozawa, E; Sekine, N; Yamamoto, M, 1993)
"Sheehan's syndrome is prone to be complicated by nontraumatic rhabdomyolysis, with both a chronic course and acute exacerbation."1.72Clinical analysis of the serum muscle enzyme spectrum of patients with newly diagnosed Sheehan's syndrome. ( Ba, J; Gao, H; Lan, Y; Li, J; Liu, Y; Tian, H; Xiang, Q; Yu, M, 2022)
"Hashimoto's thyroiditis (HT) or chronic lymphocytic thyroiditis is the most common form of primary hypothyroidism."1.48Rhabdomyolysis: a rare complication of Hashimoto's thyroiditis precipitated by statin therapy. ( Karadan, U; Manappallil, RG; Peringat, J, 2018)
"Hypothyroidism is an endocrine disease with various clinical manifestations."1.40Massive pericardial effusion and rhabdomyolysis secondary to untreated severe hypothyroidism: the first report. ( Akbarnia, S; Pourrajab, F; Rahmanian, M; Zare-Khormizi, MR, 2014)
"Rhabdomyolysis was diagnosed by elevated CK and serum myoglobin, and the difference between urinary blood occult reaction and red blood cell count."1.35[Rhabdomyolysis in a patient with postoperative hypothyroidism and hypoparathyroidism]. ( Kurihara, I, 2008)
"Acquired hypothyroidism is rare before age 3 years, and rhabdomyolysis due to hypothyroidism has not previously been reported as a cause of delayed gross-motor development in toddlerhood."1.33Onset of acquired autoimmune hypothyroidism in infancy: a presentation of delayed gross-motor development and rhabdomyolysis. ( Chiu, HK; Gunther, DF; Kletter, GB; Numrych, TE, 2006)
"Primary hypothyroidism is a chronic and insidious disease caused by failure of thyroid hormone production."1.32Hoffman's syndrome: muscle stiffness, pseudohypertrophy and hypothyroidism. ( Baldini, V; Mastropasqua, M; Paggi, A; Spagna, G; Tedesco, I, 2003)
"In this paper, we report a case of acute renal failure in a 35-year old male patient with myalgia."1.32Hypothyroid acute renal failure. ( Birewar, S; Oppenheimer, M; Zawada, ET, 2004)
"Hypothyroidism is a rare cause of rhabdomyolysis, but should always be considered in a patient with an unexplained increase in creatine kinase concentrations."1.31Hypothyroidism as a cause of rhabdomyolysis. ( Barahona, MJ; Mauri, A; Paredes, R; Sucunza, N; Wägner, AM, 2002)
"Hypothyroidism is a common cause of rhabomyolysis and hyper-cholesterolaemia and its association with lipid lowering drugs is an additional risk factor for rhabdomyolysis."1.29[Hypothyroidism, hypocholesteremic agents and rhabdomyolysis]. ( Gouton, M, 1993)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's10 (38.46)29.6817
2010's9 (34.62)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Gao, H1
Xiang, Q1
Li, J1
Yu, M1
Lan, Y1
Ba, J1
Liu, Y1
Tian, H1
Mohamed, MF1
Mahgoub, AB1
Sardar, S1
Elzouki, AN1
Varalakshmi, DB1
Ram, R1
Siva Kumar, V1
Abushalha, K1
Abulaimoun, S1
Silberstein, PT1
Manappallil, RG2
Muralidharan, R1
Shalu, S1
Haneef, F1
Salehi, N1
Agoston, E1
Munir, I1
Thompson, GJ1
Peringat, J1
Karadan, U1
McDonnell, P1
Pittman-Moore, S1
Zare-Khormizi, MR1
Rahmanian, M1
Pourrajab, F1
Akbarnia, S1
Ahmed, GS1
Zaid, HM1
Moloney, M1
Iyasere, CA1
Simmons, LH1
Fintelmann, FJ1
Dighe, AS1
Cimbek, EA1
Şen, Y1
Yuca, SA1
Çam, D1
Gür, C1
Peru, H1
Cann, RC1
Marks, DJ1
Hurel, SJ1
Laing, C1
Mouzouri, H1
El Omri, N1
Sekkach, Y1
Frikh, R1
Nzambe, C1
Qacif, H1
Baizri, H1
Makouar, F1
Qatni, ME1
Belmejdoub, G1
Rkiouak, F1
Ghafir, D1
Ohayon, V1
Archane, MI1
Chowta, MN1
Chowta, NK1
Mastropasqua, M1
Spagna, G1
Baldini, V1
Tedesco, I1
Paggi, A1
Barahona, MJ1
Mauri, A1
Sucunza, N1
Paredes, R1
Wägner, AM1
Polo Romero, FJ1
Beato Pérez, JL1
Kisakol, G1
Tunc, R1
Kaya, A1
Birewar, S1
Oppenheimer, M1
Zawada, ET1
Gunther, DF1
Chiu, HK1
Numrych, TE1
Kletter, GB1
Kiernan, TJ1
Rochford, M1
McDermott, JH1
Kurihara, I1
Gouton, M1
Sekine, N1
Yamamoto, M1
Michikawa, M1
Enomoto, T1
Hayashi, M1
Ozawa, E1
Kobayashi, T1
Harris, PA1
Snow, DH1
Greet, TR1
Rossdale, PD1

Other Studies

26 other studies available for thyroxine and Rhabdomyolysis

ArticleYear
Clinical analysis of the serum muscle enzyme spectrum of patients with newly diagnosed Sheehan's syndrome.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Aspartate Aminotransferases; Blood Glucose; Creatine Kinase; Electrolytes; Humans; Hypopituitarism;

2022
Acute psychosis and concurrent rhabdomyolysis unveiling diagnosis of hypothyroidism.
    BMJ case reports, 2019, Oct-05, Volume: 12, Issue:10

    Topics: Adult; Diagnosis, Differential; Humans; Hypothyroidism; Male; Psychotic Disorders; Rhabdomyolysis; T

2019
Rhabdomyolysis due to hypothyroidism without any precipitating factor.
    Tropical doctor, 2020, Volume: 50, Issue:3

    Topics: Adult; Humans; Hypothyroidism; Male; Rhabdomyolysis; Thyroxine; Treatment Outcome

2020
So slow, so fast, a case of nivolumab-induced hypothyroidism with subsequent rhabdomyolysis.
    Immunotherapy, 2020, Volume: 12, Issue:9

    Topics: Humans; Hypothyroidism; Immune Checkpoint Inhibitors; Male; Middle Aged; Nivolumab; Rhabdomyolysis;

2020
Hashimoto's thyroiditis aggravated by goitrogenic diet presenting as rhabdomyolysis worsened by alcohol intake.
    BMJ case reports, 2021, Jul-09, Volume: 14, Issue:7

    Topics: Alcohol Drinking; Diet; Hashimoto Disease; Humans; Male; Rhabdomyolysis; Thyroxine

2021
Rhabdomyolysis in a Patient with Severe Hypothyroidism.
    The American journal of case reports, 2017, Aug-22, Volume: 18

    Topics: Creatine Kinase; Female; Fluid Therapy; Humans; Hypothyroidism; Middle Aged; Rhabdomyolysis; Thyrotr

2017
Rhabdomyolysis: a rare complication of Hashimoto's thyroiditis precipitated by statin therapy.
    BMJ case reports, 2018, Feb-12, Volume: 2018

    Topics: Fluid Therapy; Hashimoto Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions,

2018
My aching muscles.
    Journal of the Mississippi State Medical Association, 2014, Volume: 55, Issue:4

    Topics: Adult; Creatine Kinase; Diagnosis, Differential; Female; Fluid Therapy; Hormone Replacement Therapy;

2014
Massive pericardial effusion and rhabdomyolysis secondary to untreated severe hypothyroidism: the first report.
    Acta clinica Belgica, 2014, Volume: 69, Issue:5

    Topics: Adult; Chest Pain; Dyspnea; Electrocardiography; Humans; Hypothyroidism; Male; Pericardial Effusion;

2014
Hashimoto's thyroiditis presenting as Hoffman's syndrome, rhabdomyolysis and acute kidney injury.
    BMJ case reports, 2014, Jul-04, Volume: 2014

    Topics: Acute Kidney Injury; Adult; Fluid Therapy; Follow-Up Studies; Hashimoto Disease; Hormone Replacement

2014
Case records of the Massachusetts General Hospital. Case 38-2014. An 87-year-old man with sore throat, hoarseness, fatigue, and dyspnea.
    The New England journal of medicine, 2014, Dec-11, Volume: 371, Issue:24

    Topics: Aged, 80 and over; Aspartate Aminotransferases; Creatine Kinase; Diagnosis, Differential; Dyspnea; F

2014
Kocher-Debré-Semelaigne syndrome with rhabdomyolysis and increased creatinine.
    Journal of pediatric endocrinology & metabolism : JPEM, 2015, Nov-01, Volume: 28, Issue:11-12

    Topics: Adolescent; Congenital Hypothyroidism; Creatine Kinase; Creatinine; Hashimoto Disease; Humans; Hyper

2015
Acute kidney injury after Chernobyl.
    Kidney international, 2015, Volume: 88, Issue:4

    Topics: Acute Kidney Injury; Chernobyl Nuclear Accident; Hormone Replacement Therapy; Humans; Hydroxymethylg

2015
[Severe rhabdomyolysis revealing a myopathy linked to autoimmune hypothyroidism].
    Annales d'endocrinologie, 2009, Volume: 70, Issue:1

    Topics: Humans; Hypothyroidism; Male; Middle Aged; Rhabdomyolysis; Thyroid Hormones; Thyroiditis, Autoimmune

2009
Hypothyroidism-associated rhabdomyolysis.
    Indian journal of medical sciences, 2008, Volume: 62, Issue:12

    Topics: Adult; Humans; Hypothyroidism; Male; Rhabdomyolysis; Risk Factors; Thyroxine

2008
Hoffman's syndrome: muscle stiffness, pseudohypertrophy and hypothyroidism.
    Hormone research, 2003, Volume: 59, Issue:2

    Topics: Adult; Creatine Kinase; Exercise; Female; Humans; Hypertrophy; Hypothyroidism; Muscle Fatigue; Muscl

2003
Hypothyroidism as a cause of rhabdomyolysis.
    Endocrine journal, 2002, Volume: 49, Issue:6

    Topics: Creatine Kinase; Hormone Replacement Therapy; Humans; Hypothyroidism; Male; Middle Aged; Rhabdomyoly

2002
[Hypercholesterolemia, rhabdomyolysis and hypothyroidism].
    Revista clinica espanola, 2003, Volume: 203, Issue:3

    Topics: Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypothyroidism

2003
Rhabdomyolysis in a patient with hypothyroidism.
    Endocrine journal, 2003, Volume: 50, Issue:2

    Topics: Adult; Electromyography; Humans; Hypothyroidism; Male; Muscle, Skeletal; Recovery of Function; Rhabd

2003
Hypothyroid acute renal failure.
    South Dakota journal of medicine, 2004, Volume: 57, Issue:3

    Topics: Acute Kidney Injury; Adult; Humans; Hypothyroidism; Male; Rhabdomyolysis; Thyroxine

2004
Onset of acquired autoimmune hypothyroidism in infancy: a presentation of delayed gross-motor development and rhabdomyolysis.
    European journal of pediatrics, 2006, Volume: 165, Issue:5

    Topics: Antibodies; Autoimmune Diseases; Creatine Kinase; Developmental Disabilities; Female; Hormone Replac

2006
Simvastatin induced rhabdomyolysis and an important clinical link with hypothyroidism.
    International journal of cardiology, 2007, Jul-31, Volume: 119, Issue:3

    Topics: Aged, 80 and over; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypothyroidism; R

2007
[Rhabdomyolysis in a patient with postoperative hypothyroidism and hypoparathyroidism].
    Nihon Jinzo Gakkai shi, 2008, Volume: 50, Issue:1

    Topics: Acute Kidney Injury; Aged, 80 and over; Female; Fluid Therapy; Graves Disease; Humans; Hydroxycholec

2008
[Hypothyroidism, hypocholesteremic agents and rhabdomyolysis].
    Archives des maladies du coeur et des vaisseaux, 1993, Volume: 86, Issue:12

    Topics: Adult; Anticholesteremic Agents; Cholesterol; Creatine Kinase; Humans; Hypercholesterolemia; Hypothy

1993
Rhabdomyolysis and acute renal failure in a patient with hypothyroidism.
    Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:3

    Topics: Acute Kidney Injury; Female; Humans; Hypothyroidism; Middle Aged; Patient Compliance; Peritoneal Dia

1993
Some factors influencing plasma AST/CK activities in thoroughbred racehorses.
    Equine veterinary journal. Supplement, 1990, Issue:9

    Topics: Aging; Animals; Aspartate Aminotransferases; Calcium, Dietary; Creatine Kinase; Diet; Female; Horse

1990